Civia Z. Chen is a researcher at Altos Labs. She completed her PhD at the University of Cambridge under the supervision of Prof. Robin Franklin. Her research focuses on understanding the molecular mechanisms underlying cell fate decisions of oligodendrocyte progenitor cells (OPCs) and the potential for promoting remyelination. Civia's work is funded by the Wellcome Trust as part of their Regenerative Medicine and Stem Cell Biology program. Her skills include bioinformatics, CRISPR, RNAseq, molecular biology, and tissue culture.
Education
- PhD, University of Cambridge (2017-2021)
Research Interests
Keywords:
Oligodendrocyte Progenitor Cells Schwann Cells Remyelination Regenerative Medicine Stem Cell Biology
Topics:
Neuroscience Regenerative Medicine Stem Cell Biology Cell Fate Decisions Myelination
Professional Links
Selected Publications
Cognitive benefits of folic acid
Xu M, Zhu Y, Chen J, Li J, Qin J, et al. Effects of folic acid supplementation on cognitive impairment: A meta-analysis of randomized controlled trials. J Evid Based Med. 2024;17:134. doi:10.1111/jebm.12588
Folate metabolism and Alzheimer's
Yu Y, Chen CZ, Celardo I, Tan BWZ, Hurcomb JD, et al. Enhancing mitochondrial one-carbon metabolism is neuroprotective in Alzheimer's disease models. Cell Death Dis. 2024;15:856. doi:10.1038/s41419-024-07179-3
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