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Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B-6 (as Pyridoxine Hydrochloride)
10 mg
590%
Calcium (from Calcium Carbonate)
63 mg
4%
Melatonin
3 mg
*
The product is found useful for the following medical conditions
Back Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Relief from pain
Most Useful Review
Natrol Melatonin 3mg is a brilliant product! After enduring insomnia caused by back pain, I discovered iHerb and this melatonin. It's my best purchase yet! They're made from high-quality ingredients, are the perfect size, and taste pleasant. I take one each night with water, no chewing required! They began working from the very first night; I now sleep well without feeling pain and awaken much more refreshed. I would highly recommend these to anyone seeking a good night's sleep!
Insomnia
SCIENTIFIC SCORE
Most Likely Effective
Based on 13 Researches
8.2
USERS' SCORE
Very Good
Based on 64 Reviews
7.6
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Most Relevant Research
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
9.5
Improved sleep quality
Most Useful Review
Working well. This supplement truly aids my sleep. After struggling with insomnia, I now wake up feeling refreshed and cheerful. Before taking melatonin, I had difficulty sleeping and waking up. I no longer need an alarm clock. I recommend GABA for anyone facing similar insomnia issues.
Headache
SCIENTIFIC SCORE
Most Likely Effective
Based on 14 Researches
7.6
USERS' SCORE
Medium or Average
Based on 20 Reviews
6.7
9.5
Agomelatine relieves hypnic headaches
Case report: Hypnic headache responds to agomelatine-a potential prophylactic treatment option.
Most Relevant Research
We explored how melatonin-based treatments, particularly agomelatine, can affect headaches, focusing on hypnic headaches (HH). This form of headache typically occurs during sleep, disrupting the rest of those affected. A fascinating case of a 58-year-old woman who experienced these nocturnal headaches for three years demonstrated the potential benefits of agomelatine.
After being prescribed 25 mg of agomelatine at bedtime, she reported an impressive 80% reduction in headache frequency and severity within a month. Remarkably, her headaches completely resolved after three months, allowing her to discontinue the medication.
This case highlights the importance of exploring prophylactic treatments aimed at reducing nighttime awakenings caused by HH. Given the significant impact these headaches can have on sleep quality in older populations, treatments that target melatonin receptors could offer a promising avenue for relieving this condition.
After being prescribed 25 mg of agomelatine at bedtime, she reported an impressive 80% reduction in headache frequency and severity within a month. Remarkably, her headaches completely resolved after three months, allowing her to discontinue the medication.
This case highlights the importance of exploring prophylactic treatments aimed at reducing nighttime awakenings caused by HH. Given the significant impact these headaches can have on sleep quality in older populations, treatments that target melatonin receptors could offer a promising avenue for relieving this condition.
8.3
Good for headaches
Most Useful Review
My neurologist advised taking 3 mg nightly to alleviate symptoms of trigeminal autonomic cephalalgia. This is more effective and less taxing than other medications, which caused debilitating side effects.
Sleep Apnea
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 70 Reviews
6.6
10
Restorative sleep
Most Useful Review
Melatonin has helped me establish a normal sleeping routine after years of insomnia, which impacted my health. I began sleeping more naturally again at midnight, and it significantly relieved my sleep apnea problems. I can now sleep well.
