Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid, Acerola Cherry, Rose Hips)
1,000 mg
1,111%
The product is found useful for the following medical conditions
Reflux details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 6 Reviews
8.8
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
9
No reflux issue
Most Useful Review
3 people found this helpful
Good! Despite its size, the capsule has a coating that makes it easy to swallow. The two-stage time release allows for longer bioavailability compared to regular vitamin C. It has no flavor whatsoever and does not cause me acid reflux or any aftertaste, even when taken at bedtime. It is very beneficial for iron absorption.
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Effective for cough
Most Useful Review
4 people found this helpful
It works for chronic cough. I'm 45 and take 2000mg vitamin C and 1000mg vitamin B5 twice daily for my skin and to strengthen my immune system, along with a multivitamin in the morning. When I experience a chronic cough and burning throat, I take 2000mg to 3000mg of vitamin C and 2000mg of vitamin B5 every two hours until it stops, and it always works. I hope this helps.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
We explored how ice water vestibular stimulation affects ascorbic acid (AA) levels in the brain, particularly in relation to dizziness. Using a method called in vivo microdialysis coupled with electrochemical detection, we monitored changes in extracellular AA in the primary somatosensory area of guinea pigs. Our study included 16 guinea pigs divided into three groups: one group received ice water stimulation, while the other two were exposed to warm water and ice water without vestibular input.
The results revealed that the concentration of extracellular AA increased in the brain following the ice water stimulation. This finding suggests that there may be neurochemical responses associated with AA that play a role in managing conditions like vertigo. However, while the study shows an intriguing relationship between AA levels and vestibular stimulation, it does not establish a direct link between vitamin C's effectiveness in treating dizziness specifically.
Overall, the insights gained from this research could help pave the way for further investigations into the role of vitamin C in vertigo-related treatments, adding a layer of understanding to its neurochemical functions.
The results revealed that the concentration of extracellular AA increased in the brain following the ice water stimulation. This finding suggests that there may be neurochemical responses associated with AA that play a role in managing conditions like vertigo. However, while the study shows an intriguing relationship between AA levels and vestibular stimulation, it does not establish a direct link between vitamin C's effectiveness in treating dizziness specifically.
Overall, the insights gained from this research could help pave the way for further investigations into the role of vitamin C in vertigo-related treatments, adding a layer of understanding to its neurochemical functions.
9
Reduces dizziness
Most Useful Review
I ordered this vitamin for my mother. She appreciates her condition after taking this vitamin C, as it remains in the body for longer and yields positive results. It alleviates dizziness and mental cloudiness.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.5
9
Effective for colds
Most Useful Review
This is always in my first aid kit. During cold seasons, it rapidly gets me back on my feet.
Frozen Shoulder details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
In our controlled laboratory study, we aimed to investigate whether vitamin C could help prevent frozen shoulder, particularly the secondary type that often occurs after trauma or surgery. We created a shoulder contracture model using Sprague-Dawley rats, which involved immobilizing their right shoulder.
Our experimental group, consisting of eight rats, received vitamin C orally, while a control group of nine rats did not receive vitamin C. We primarily measured the thickness of the joint capsule at the shoulder using magnetic resonance imaging (MRI).
The results were promising, indicating that vitamin C may reduce the thickening of the joint capsule linked to secondary frozen shoulder. Although we also conducted histological examinations, we did not perform statistical analysis on those findings due to variability in our cutting techniques.
This preclinical study suggests that vitamin C could be a valuable, non-invasive way to prevent secondary frozen shoulder, particularly in situations involving surgery or immobilization. However, more research is needed to determine its effects on humans and establish proper dosage guidelines.
Our experimental group, consisting of eight rats, received vitamin C orally, while a control group of nine rats did not receive vitamin C. We primarily measured the thickness of the joint capsule at the shoulder using magnetic resonance imaging (MRI).
The results were promising, indicating that vitamin C may reduce the thickening of the joint capsule linked to secondary frozen shoulder. Although we also conducted histological examinations, we did not perform statistical analysis on those findings due to variability in our cutting techniques.
This preclinical study suggests that vitamin C could be a valuable, non-invasive way to prevent secondary frozen shoulder, particularly in situations involving surgery or immobilization. However, more research is needed to determine its effects on humans and establish proper dosage guidelines.
9
No more stiffness
Most Useful Review
I believe it is effective. After around six months of consistent consumption, I have nearly no stiffness in my shoulders, and I rarely catch colds or fall ill. Thus, I feel it has made a significant difference.
Lung Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
We explored the effects of vitamin C on lung cancer, particularly its ability to inhibit pulmonary metastasis—meaning the spread of cancer to the lungs. Using an H22 pulmonary metastasis mouse model, we observed that vitamin C administration, both intraperitoneally and orally, showed promising results.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
9
Cold prevention
Most Useful Review
I take it to prevent cancer and colds. Since starting, I can spend my days without catching a cold!
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
9
Effective daily protection
Most Useful Review
1 people found this helpful
This product provides effective, time-released protection all day.
Sore Throat details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8.4
9
Quick recovery
Most Useful Review
2 people found this helpful
I bought this product to replace my previous one, and I’m thrilled with the results. As soon as I feel a sore throat or signs of sickness, I take a capsule and rest, and my symptoms disappear rapidly. This is particularly crucial during a pandemic, so I highly recommend it!
Back Pain details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.3
USERS' SCORE
Good
Based on 2 Reviews
8.3
4
We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
7.5
Improved skin condition
Most Useful Review
I feel my skin has become beautiful. I used to take 500mg of vitamin C three times a day, but after trialling a new brand, I've noticed my skin is in better condition over two weeks. My back pain is also easing, and I plan to continue taking it as is.
Blood Clot details
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
9
Effectively thins blood
Most Useful Review
The husband had a mild form of Covid, and at over 65, it was impressive that he recovered with the help of vitamins. I administered 5000 units, 15,000 units of vitamin D, omega, and zinc for a week, then reduced the dosage. I also contracted Covid but was asymptomatic, thanks to vitamins since 2019. The dosage is excellent, with no heartburn or allergic reactions. I take it daily after breakfast and highly recommend it!
Cardiovascular Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.3
7
Vitamin C enhances NK cell proliferation
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
9
Reduces cold symptoms
Most Useful Review
2 people found this helpful
I love vitamin C, which is essential for combating cardiovascular disease and boosting immunity. It’s crucial if you experience symptoms like bleeding gums and dry skin. During my recent Covid illness, I doubled the dose and had a mild experience. I recommend keeping it in your medicine cabinet and taking it regularly.
Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.3
10
Stops coughing
Most Useful Review
4 people found this helpful
This works for coughing! I take 2000mg of vitamin C with 1000mg of vitamin B5 in the morning and evening. When I get a cough or burning throat, I increase my intake to 2000-3000mg every few hours until the cough subsides, and it always does.
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.3
7
Antioxidants tested for heart attacks
In a recent clinical trial, we examined how a combination of antioxidants, including vitamin C, affects heart attack recovery. This study involved healthy participants who received either a blend of antioxidants or a placebo through an intravenous infusion. We measured the levels of vitamin C and other components in the blood, looking for signs of oxidative stress and monitoring any adverse effects.
Our findings showed that the antioxidant combination significantly increased vitamin concentrations compared to the placebo group. Moreover, we observed that this therapy seemed safe, with only mild, non-serious side effects reported in a small number of participants.
While antioxidants like vitamin C have been linked to health benefits, this study focused primarily on their safety and levels in the blood during a heart-related procedure. Although promising, we cannot definitively say that this approach improves outcomes for heart attack patients just yet. More research will be needed to explore its effectiveness further.
Our findings showed that the antioxidant combination significantly increased vitamin concentrations compared to the placebo group. Moreover, we observed that this therapy seemed safe, with only mild, non-serious side effects reported in a small number of participants.
While antioxidants like vitamin C have been linked to health benefits, this study focused primarily on their safety and levels in the blood during a heart-related procedure. Although promising, we cannot definitively say that this approach improves outcomes for heart attack patients just yet. More research will be needed to explore its effectiveness further.
8
May lower stroke risk
Most Useful Review
Vitamin C may reduce stroke risk due to its antioxidant properties and potential role in heart health. A 2013 study, analysing 16 studies, found that those consuming high amounts of vitamin C (45 mg to 1,167 mg daily) had a lower risk of stroke. Specifically, intake of 200 mg to 550 mg per day resulted in the greatest reduction of stroke risk. Although exact mechanisms are unclear, it is believed that vitamin C lowers blood pressure and reduces inflammation.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Helps inflammation
Most Useful Review
Ascorbic acid is beneficial in the body's battle against various infections and viruses. It aids with inflamed lymph nodes, strengthens blood vessel walls, cleanses the blood, and eliminates free radicals.
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.2
9
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
9
Iron deficiency aid
Most Useful Review
I ensure I address my iron deficiency anemia by consistently taking 0.5 tablets of vitamin C with my iron supplements.
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 12 Reviews
8.2
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
9
Cold sore relief
Most Useful Review
151 people found this helpful
I took one jar of this product for three months, and during that period, I completely forgot about having any cold sores.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
9
Excellent vitamin escape
Most Useful Review
I've been taking vitamin C for three years, prompted by Dr. Tokumi Fujikawa's recommendations. Previously, I often caught colds and had a sore throat, but now I haven’t been ill for two years. This excellent vitamin has aided in alleviating my depression and functional dyspepsia, particularly relevant given my age. I comfortably take two tablets each morning and evening. Though swallowing them was tricky at first, it became easier, and now I consider it essential for immunity, especially during these times.
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.2
USERS' SCORE
Good
Based on 98 Reviews
8.2
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
9
Most effective vitamin
Most Useful Review
16 people found this helpful
I’ve tried many brands but keep coming back to this one. I take one capsule twice a day and have found it most effective against colds and the flu. If vitamin C isn’t working, adjust your dosage to bowel tolerance to see benefits. After decades of experience, it’s clear this one is the most potent for me.
Gastritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.2
8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
9
No consequences noted
Most Useful Review
For a gastritis patient – I administered this to a patient with gastritis, and everything went fine without any adverse effects.
Headache details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
9
Stomach friendly
Most Useful Review
Good! An excellent vitamin that does not irritate the stomach and effectively relieves headaches.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.2
7
We aimed to understand the role of vitamin C in heart disease and its potential cardioprotective effects. Vitamin C is renowned for its antioxidant properties, which means it fights off harmful substances in our body, potentially reducing the risk of heart issues.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
9
Stroke risk reduction
Most Useful Review
Vitamin C may play a role in reducing stroke risk. A 2013 study found that those consuming higher amounts of vitamin C had a lower stroke risk. Although the exact mechanism is unclear, it may relate to blood pressure reduction and inflammation control, ultimately affecting heart disease.
Whooping Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.2
9
Cough relief achieved
Most Useful Review
4 people found this helpful
It works well for coughing. At 45, I take 2000mg of vitamin C and 1000mg of vitamin B5 each morning and night for skin and immunity support, along with a multivitamin in the morning. When I experience coughing or a burning throat, I take 2000mg - 3000mg of vitamin C and 2000mg of vitamin B5 every two hours until the cough subsides, and it consistently works. I hope it helps others as well.
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 6 Reviews
8.1
9
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
9
Improved skin health
Most Useful Review
5 people found this helpful
Solaray is of high quality! It greatly aids sleep disorders, strengthens mucous membranes, and enhances skin complexion. I strongly believe all Solaray’s supplements are outstanding. This vitamin C's formulation, including rosehip and acerola, is effective and is gently released over 12 hours. It helped me overcome a severe sleep disorder lasting nine and a half years. Thanks to its antioxidant property, I also enjoy improved immunity and have stronger mucous membranes, resulting in fewer colds. My skin glows daily—I'm truly grateful.
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 5 Reviews
8.1
7
We aimed to explore how different measures of vitamin C might influence premenstrual symptoms, particularly bloating. In this study, we analyzed data from 555 women aged 20 to 29 years who reported on various symptoms associated with their menstrual cycles. We looked at their dietary intake of vitamin C, measured serum ascorbic acid levels, and assessed genetic factors through DNA testing.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
9
No bloating experienced
Most Useful Review
Since it contains rosehip, it is easy for the body to adapt, making it feel more natural. The time-release aspect allows for a significant absorption of vitamin C. There was no bloating or stomach pain.
Bruise details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Good
Based on 4 Reviews
8.1
8
We explored how vitamin C can impact bruising, particularly in individuals experiencing a deficiency. The research highlighted a case involving an elderly woman who faced challenges such as weakness, easy bruising, and fatigue due to a lack of this vital nutrient.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
9
Disappeared bruises
Most Useful Review
3 people found this helpful
Favourite vitamin C, helps during a cold, bruises have also vanished and my gums stopped bleeding.
Influenza details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 9 Reviews
8.1
7
We explored the relationship between vitamin C and influenza, delving into various studies conducted from 2000 to June 2021. In our analysis of the research, we found eleven studies that specifically examined the effects of vitamin C on influenza.
While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.
Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.
Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.
Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.
Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
7.5
Energy boost
Most Useful Review
5 people found this helpful
It provides energy and is effective in preventing and treating colds and influenza.
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 17 Reviews
8
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9
Skin and allergies
Most Useful Review
27 people found this helpful
I originally bought it for my weak skin and acne. I now take two tablets daily, and my skin has firmed up. Vitamin C appears beneficial for allergies and stress; I’ll continue taking it with my family.
Bacterial Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8
9
Supports immunity well
Most Useful Review
4 people found this helpful
I recommend this extended release vitamin C with a dosage of 1000 mg. It gradually releases into the bloodstream over 6-8 hours, creating stable vitamin C levels. It supports collagen synthesis, immune function, and has a beneficial effect on the nervous system. It strengthens immunity and protects against viral and bacterial infections. I take it after breakfast.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 666 Reviews
8
7
Effectiveness of Vitamin C on Colds
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
10
No more colds
Most Useful Review
151 people found this helpful
I took one jar of this drug for three months, and during this period, even after finishing the medication, I completely forgot about all colds.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8
9
Stronger bowel movements
Most Useful Review
I take Solaray sustained-release vitamin C along with Doctor's Best MSM with OptiMSM, and my bowel movements are very strong.
Adrenal Gland Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
9
Skin condition improved.
Most Useful Review
2 people found this helpful
After using iHerb's original vitamin C for ages, I switched to this, and it feels fantastic. I can sense it working in my body. My worries about spots and rough skin are fading, and I find this vitamin C beneficial for my adrenal glands and overall health. I'd like to purchase it again.
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Moderately Good
Based on 130 Reviews
7.9
8
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
7.5
Immune system boost
Most Useful Review
185 people found this helpful
Vitamin C strengthens the immune system, guarding against viruses and bacteria while speeding up wound healing. This product features an extended release formula, ensuring long-lasting availability of vitamin C. My family takes it for small courses in autumn and spring. I highly recommend it.
Kidney Stones details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
4
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
9
Supports kidney health
Most Useful Review
Good for kidneys and boosts immunity during colds.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.9
10
No issues experienced
Most Useful Review
Super vitamin C! The quality is impressive, and I didn't experience any allergies or rashes while using it.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.8
9
No stomach pain
Most Useful Review
5 people found this helpful
Good, high-quality vitamin C. My stomach problems made it hard to take vitamin C (pain begins), but with this vitamin, everything is fine. I experience no stomach discomfort and take it daily.
Eczema details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.8
7
We assessed the impact of vitamin C and other nutrients on workers suffering from skin eczema due to their job in perlite production. The study involved a group of 165 workers with eczema and a control group of 152 workers without any skin issues, allowing us to compare the effects more accurately.
Participants were included on a specialized diet featuring kissel, rich in pectin, vitamin A, vitamin E, and zinc. Notably, we saw significant improvements in several important indicators. For instance, the levels of ascorbic acid in the blood increased by 30%, while tocopherol levels rose by 36.3%. Additionally, we observed enhanced levels of carotenoids, phosphorus, and calcium.
There was a notable reduction in malondialdehyde (MDA), which can indicate oxidative stress, alongside a slight increase in catalase activity, suggesting overall improvements in the body’s ability to fight inflammation. While these findings suggest a positive trend towards reducing symptoms such as itching and redness, it’s essential to note that the study didn't isolate the effects of vitamin C alone, leaving us without a clear conclusion on its specific role in relieving eczema.
Consequently, while the combination of nutritional factors, including vitamin C, shows promise in enhancing skin health and fighting occupational eczema, we need further research to fully understand how much of this benefit can be attributed to vitamin C by itself.
Participants were included on a specialized diet featuring kissel, rich in pectin, vitamin A, vitamin E, and zinc. Notably, we saw significant improvements in several important indicators. For instance, the levels of ascorbic acid in the blood increased by 30%, while tocopherol levels rose by 36.3%. Additionally, we observed enhanced levels of carotenoids, phosphorus, and calcium.
There was a notable reduction in malondialdehyde (MDA), which can indicate oxidative stress, alongside a slight increase in catalase activity, suggesting overall improvements in the body’s ability to fight inflammation. While these findings suggest a positive trend towards reducing symptoms such as itching and redness, it’s essential to note that the study didn't isolate the effects of vitamin C alone, leaving us without a clear conclusion on its specific role in relieving eczema.
Consequently, while the combination of nutritional factors, including vitamin C, shows promise in enhancing skin health and fighting occupational eczema, we need further research to fully understand how much of this benefit can be attributed to vitamin C by itself.
10
No more dermatology
Most Useful Review
I wanted to try biotin therapy for my hand eczema. After six months of taking biotin and acidophilus, I no longer suffer from eczema! I’m thrilled not to have to visit dermatology any longer. Previously, I applied hand cream and wore cotton gloves, but now, I highly recommend it to housewives and hairdressers who regularly deal with water. The tablets were initially large and hard to swallow, which is why I gave it four stars.
Leg Cramps details
SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.8
5
We explored the effects of vitamin C on leg cramps in a group of 60 pregnant women through a double-blind trial. Participants received either calcium or vitamin C (1 g twice daily) as treatment. Our observations revealed that there was no significant difference in clinical improvement between the two treatment groups.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
10
Managed leg cramps
Most Useful Review
Great! My anxiety has decreased significantly; I feel much more confident and calmer. My sleep has returned to normal; I now fall asleep quickly and sleep through the night without issues. I no longer experience muscle spasms, and my legs don't ache due to weather or fatigue. My blood pressure is stable, and I actually have fewer headaches now, which is a delightful and significant benefit of taking magnesium. Headaches often arise from vascular spasms, and magnesium effectively addresses this issue. I recommend it to everyone! The size is perfect, and the taste is pleasant. The ingredients are natural and positively impact health.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 34 Reviews
7.7
9
Rapid recovery noted
Most Useful Review
3 people found this helpful
The capsule measures 2 centimetres long and 8 millimetres thick. I take them to prevent colds and sunburn. They work well when taken multiple times a day after meals, especially if you have a sore throat. I noticed that any usual inflammation or fatigue improved significantly, and I felt better within two days. I was sceptical about the efficacy as I didn't taste them, but I would recommend this method before seeking medical attention. However, do proceed cautiously with the dosage to avoid digestive issues.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Moderately Good
Based on 22 Reviews
7.7
7
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
9
Fatigue reduction
Most Useful Review
52 people found this helpful
I recently started taking this vitamin C1000 alongside B complex in the morning and niacin at night. It’s very effective; I feel refreshed, less fatigued, and my skin is much clearer.
Heartburn details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 22 Reviews
7.7
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9
No heartburn experienced
Most Useful Review
5 people found this helpful
Super! I used to experience heartburn with vitamin C, particularly with capsule forms. However, I've found this one perfect; it does not induce heartburn. I take it after heavy meals, and my muscles feel less fatigued during training. Additionally, when I sense a cold coming on, I increase my dosage, and it works wonders. The 1000 mg capsules are convenient, and I recommend it highly!
Diarrhea details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.6
9
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
10
Large doses manageable
Most Useful Review
These tablets are fantastic for achieving larger vitamin C doses without causing diarrhoea. I take three throughout the day for maximum benefit.
Migraine details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.6
8
We explored the connection between dietary vitamin C and migraines using data from the National Health and Nutrition Examination Survey (NHANES) that covered several years from 1999 to 2004. In our analysis, we found that 4101 participants reported their migraine experiences, with over 17% indicating they had faced them recently. Using a detailed dietary recall system to assess vitamin C intake, we conducted various statistical analyses to understand the potential effects of vitamin C on migraine occurrence.
What we discovered was quite intriguing: higher dietary vitamin C intake seemed to be associated with a lower likelihood of experiencing migraines. Specifically, our results showed that those in the highest intake category had a significantly reduced risk of migraines compared to those with the lowest intake. The odds ratio indicated that for every increase in vitamin C intake, the likelihood of migraines decreased.
This linear relationship suggests that incorporating more vitamin C-rich foods into our diets could be beneficial for individuals prone to migraines. Our findings indicate that vitamin C may serve as a useful dietary consideration for managing migraine severity and frequency. Overall, these insights could pave the way for further research and highlight the importance of nutrition in migraine management.
What we discovered was quite intriguing: higher dietary vitamin C intake seemed to be associated with a lower likelihood of experiencing migraines. Specifically, our results showed that those in the highest intake category had a significantly reduced risk of migraines compared to those with the lowest intake. The odds ratio indicated that for every increase in vitamin C intake, the likelihood of migraines decreased.
This linear relationship suggests that incorporating more vitamin C-rich foods into our diets could be beneficial for individuals prone to migraines. Our findings indicate that vitamin C may serve as a useful dietary consideration for managing migraine severity and frequency. Overall, these insights could pave the way for further research and highlight the importance of nutrition in migraine management.
9
Migraine alleviated
Most Useful Review
I take 2 tablets every morning and evening. Initially, I started with 1 tablet twice a day. After increasing to 2 tablets, I noticed a significant improvement in my migraine headaches. It has become indispensable for me.
Constipation details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.5
8
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
9
Prevents constipation
Most Useful Review
1 people found this helpful
A staple supplement in our household! I always order this high-quality, long-lasting vitamin C. I take one tablet in the morning and one in the evening. A great benefit is that it effectively prevents constipation. When taken at the onset of a cold, I find I recover quickly.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.3
9
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
9
Diminished acne scars
Most Useful Review
2 people found this helpful
Surprisingly, this has worked wonders for me! Most of my acne scars have faded significantly. I've previously used medication from a dermatologist, but this is even better! It helps with cold prevention and general wellbeing, so I'll definitely keep using it. The taste is slightly lemony and although the tablet is large, my family cuts it in half.
Nausea details
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
2
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.3
2
Vitamin C ineffective against nausea
We explored the effects of vitamin C as a treatment for nausea and vomiting in pregnancy, also known as emesis gravidarum. Our study involved 111 participants, who were given either vitamin C-containing chewing gum, a placebo, or no treatment at all. We monitored them over two follow-up visits in early pregnancy to assess their symptoms.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
9
Energised feeling
Most Useful Review
After taking this time-release vitamin C, I feel truly energised, and it surprisingly doesn’t cause any side effects on my stomach. I usually experience nausea with vitamin C, but not this time.
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.5
9.5
We conducted a double-blind trial involving sixteen individuals with chronic foot ulcers to see how vitamin C impacts their healing. Half of the participants received 500 mg of vitamin C, while the others got a placebo.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
9
Cold avoidance
Most Useful Review
Taking this time-release vitamin C has helped me avoid mouth ulcers and colds effectively.
