Last update
4/14/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid, Acerola Cherry, Rose Hips)
1,000 mg
1,111%
📅 Last updated:

Top Medical Research Studies

8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

Most Useful Reviews

9
Effective heartburn relief
1 people found this helpful
After having heartburn with capsule-type vitamin C, I switched to this tablet form and I'm pleased to report no heartburn issues since I started taking it.
Read More
9
Consistent heartburn management
1 people found this helpful
This time-lag vitamin C is excellent for steadily enhancing blood vitamin C levels without causing heartburn. I haven't used it for megadoses, but it's working well for me.
Read More
9
Heartburn-free solution
1 people found this helpful
This vitamin C is of good quality and features long-release properties. I am satisfied as it doesn’t cause me any heartburn. I definitely recommend it!
Read More

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SCIENTIFIC SCORE
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USERS' SCORE
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American Health Ester-C With Citrus Bioflavonoids
SCIENTIFIC SCORE
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USERS' SCORE
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Life Extension Vitamin C and Bio-Quercetin
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21st Century Acidophilus Probiotic Blend
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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective heartburn relief
1 people found this helpful
After having heartburn with capsule-type vitamin C, I switched to this tablet form and I'm pleased to report no heartburn issues since I started taking it.
Read More
9
Consistent heartburn management
1 people found this helpful
This time-lag vitamin C is excellent for steadily enhancing blood vitamin C levels without causing heartburn. I haven't used it for megadoses, but it's working well for me.
Read More
9
Heartburn-free solution
1 people found this helpful
This vitamin C is of good quality and features long-release properties. I am satisfied as it doesn’t cause me any heartburn. I definitely recommend it!
Read More
9
No heartburn complaints
1 people found this helpful
The quality of this vitamin C is excellent. I noticed improvement after a month, especially for the elderly. It's a great antioxidant, does not induce heartburn, and is easily consumed.
Read More
9
Heartburn-free dosage
My husband managed Covid mildly thanks to this vitamin. I gave him a high dosage, and it worked well without causing heartburn or allergic reactions. I take it daily after meals and recommend it highly!
Read More

Frequently Asked Questions

9
No heartburn complaints
1 people found this helpful
The quality of this vitamin C is excellent. I noticed improvement after a month, especially for the elderly. It's a great antioxidant, does not induce heartburn, and is easily consumed.
9
Effective heartburn relief
1 people found this helpful
After having heartburn with capsule-type vitamin C, I switched to this tablet form and I'm pleased to report no heartburn issues since I started taking it.
7.5
Heartburn initially present
1 people found this helpful
I initially suffered from awful heartburn after taking this supplement but my body has since adjusted, allowing me to take it without any issues now.
0
Redness experienced
High dosage caused redness on my chest and heartburn; it was likely too much. I did not appreciate the effect.
9
No heartburn experienced
This vitamin is ideal as it doesn’t cause heartburn. I'm currently on high-dose therapy, and I’m very pleased with the results.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.

References

  1. Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
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