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Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate) 
268 mg 
1787%

The product is found useful for the following medical conditions

Pelvic Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 31 Reviews
8.9
8.8
Reduced pelvic pain
Most Useful Review
Rejuvenating vitamins! I have suffered from pelvic pain linked to PMS and heavy menstrual bleeding for years. After following advice on Professor Fujikawa's blog to take vitamins C, E, D3, K2, and magnesium, I've noticed a significant reduction in my symptoms. My irritability before the period has improved, and the excessive bleeding has decreased. This has made my menstruation far more manageable!

Leg Cramps

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 20 Reviews
8.8
7
Vitamin E's potential in leg cramps
Are there alternatives to the use of quinine to treat nocturnal leg cramps?
Most Relevant Research
We explored the potential role of vitamin E in treating leg cramps, particularly in populations such as those undergoing dialysis. The study aimed to understand if vitamin E could provide relief from troublesome nocturnal leg cramps—an issue that many individuals face.

While the effects of quinine, a common treatment, have been closely scrutinized, vitamin E emerges as a noteworthy alternative. Although large-scale randomized controlled trials focusing specifically on vitamin E for leg cramps are limited, some data suggest that it may hold promise for alleviating symptoms. This is especially true for those who might not respond to other treatments.

We observed that incorporating vitamin E could be a safer option, as this supplement generally has a more favorable safety profile compared to quinine. However, it's important to underscore that patients should consider exploring other treatments before turning to quinine, particularly given the latter's potential side effects.
9.5
Cramps disappeared
Most Useful Review
I have suffered from severe leg cramps, and after being advised to take this supplement for about 3 months, I noticed a reduction in pain. By the second month, the pain had entirely vanished! Previously, it was so intense that I struggled to walk, but now I can manage comfortably without issues. I will continue to take it.

Blood Clot

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 38 Reviews
8.7
9.5
Fighting toxins
Most Useful Review
The most valuable female vitamin! Taking 400 IU daily protects against heart attacks and improves blood circulation. Vitamin E thins the blood naturally and eliminates harmful fats. It’s non-toxic compared to blood thinners. I take it alongside omega acids for optimal absorption and self-cleaning of cells.

Breast Cancer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.7
9.5
Cancer prevention benefits
Most Useful Review
I consistently take Vitamin E due to its benefits, especially for women over 40. It aids in cleansing the body, boosts immunity, slows ageing, restores cells, and reduces the risk of breast cancer.

Cold Sores

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Alleviated cold symptoms
Most Useful Review
I started taking Vitamin E to improve blood flow. Initially, I increased my dosage too quickly, which I later realised was not advisable. However, my cold extremities disappeared, and I no longer have cold hands and feet, even in winter. Stopping the supplement brought back my tinnitus, but taking it again made me feel better.

Common Cold

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 19 Reviews
8.6
9.5
Eased cold symptoms
Most Useful Review
My blood circulation has long been poor, causing my toes to feel extremely cold in winter, even in a warm room. Since taking megavitamin, that issue has improved. I also realised a lack of vitamin E leads to redness and itchiness in my toes during winter. Thank you for this successful product!

Heart Attack

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.6
9.5
Heart attack prevention
Most Useful Review
Vitamin E is vital! Taking 400 IU daily significantly protects against sudden heart attacks and improves blood circulation without toxicity. It aids in protein synthesis and helps cleanse the blood of harmful fats. I ensure to take it with fats for optimal absorption, which has helped prevent wrinkles and support my overall health.

High Cholesterol

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8.6
9.5
Strong antioxidant benefits
Most Useful Review
I find Vitamin E to be a vital antioxidant that protects against heart attacks and cleanses the blood, improving circulation without toxicity, unlike some anticoagulant drugs. I take it with omega acids for better absorption, especially helpful for my high cholesterol condition.

Knee Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Eased menstrual pain
Most Useful Review
It worked for my menstrual pain. During heavy periods, I struggled for up to two days, but after starting Vitamin E, my experience improved significantly. It felt like the blood flowed more smoothly.

Liver Disease

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.6
9.5
Absorbs well
Most Useful Review
Don't be misled by other tocopherol forms; we need alpha-tocopherol. This product offers the alpha form, which is what the body absorbs. Other tocopherols get destroyed in the liver. Alpha-tocopherol has a specific protein to aid absorption, so avoid overloading your liver with forms that cannot be absorbed easily.

Prostate Cancer

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 9 Reviews
8.6
8
Gamma-tocopherol and prostate cancer
Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.
Most Relevant Research
We dove into the fascinating realm of gamma-tocopherol, a key form of vitamin E, to understand its impact on prostate cancer treatment. Research indicates that gamma-tocopherol possesses strong antioxidant and anti-inflammatory properties, which could potentially translate into benefits for those facing prostate cancer.

Specifically, we observed that gamma-tocopherol neutralizes harmful reactive oxygen and nitrogen species in the body. This action not only protects cells from oxidative damage but also helps reduce chronic inflammation, a factor often linked to cancer progression.

What truly caught our attention was gamma-tocopherol's multifaceted role in cancer therapy. Evidence suggests that it may inhibit tumor growth, induce apoptosis (the process of programmed cell death), and even suppress the formation of new blood vessels that tumors require to grow. This makes it particularly interesting for managing prostate cancer, alongside its impact on other cancers.

Despite this promising profile, we find that high doses of gamma-tocopherol require careful consideration to avoid potential adverse effects. Overall, while gamma-tocopherol shows potential in understanding and managing prostate cancer, further research is necessary to fully grasp its effectiveness in clinical settings.
8.8
Antioxidant benefits
Most Useful Review
Prostate cancer treatment benefits all men, regardless of age. For better absorption, I find it more effective when taken after meals and separately from magnesium and vitamin D3. Women also benefit as it serves as an antioxidant for youth and beauty.

Hot Flashes

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Good
Based on 1 Review
8.6
8
Vitamin E reduces hot flashes
Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women: A triple-blind placebo-controlled clinical trial.
Most Relevant Research
We conducted a study with eighty-four postmenopausal women to see how vitamin E affects hot flashes, among other health markers. The participants were divided into three groups and received either Vitamin E, Curcumin, or a placebo for eight weeks.

Our findings revealed that vitamin E significantly reduced the frequency of hot flashes by nearly one-third compared to those taking the placebo. This reduction was accompanied by improvements in several health indicators, including lower serum triglyceride levels and enhanced high-density lipoprotein (HDL) cholesterol.

Furthermore, vitamin E also showed positive effects on liver health markers. Overall, it appears that vitamin E is effective not only in alleviating hot flashes but also in improving some aspects of the lipid profile in postmenopausal women, without adverse effects on liver or kidney function.
9.5
Daily relief
Most Useful Review
This helps me with hot flashes. I don’t experience them when taking a daily dose.

Back Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.5
9.5
Effective for back pain
Most Useful Review
Good results! I felt an improvement in my back pain after just one day of taking it along with vitamin E and B complex. The dosage is high, but the small particles make it easy to swallow, and the large packaging means it lasts a long time. I recommend it!

Bone Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.5
9.5
Reduced menstrual pain
Most Useful Review
It helped with my menstrual pain. When my periods were heavy, I struggled for two days. After starting Vitamin E, I found it much easier, likely because it aids blood flow.

Chronic Cough

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
8.8
Mucosa repair
Most Useful Review
It is quite helpful in repairing the nasal mucosa and assists with my chronic cough due to rhinitis.

Frozen Shoulder

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 18 Reviews
8.5
9.5
Relieved stiffness
Most Useful Review
After giving birth, I felt stiffness in my right hand and pain spreading to my left hand, shoulder, and knee. I suspected rheumatism but couldn’t find a cause. Following advice from Professor Fujikawa, I began taking E400. Now, the stiffness in my shoulders and knees has almost gone, and I’ll continue taking E400 even after my frozen shoulder heals.

Hypothyroidism

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 1 Review
8.5
9
Vitamin E protects hypothyroid tissues
Vitamin E Prevented Hepatic and Renal Tissue Damage in Hypothyroid Rats.
Most Relevant Research
We explored the impact of vitamin E on liver and kidney health in rats affected by hypothyroidism. To conduct this research, we divided the rats into three groups: a control group, a group with induced hypothyroidism treated with propylthiouracil (PTU), and a third group with hypothyroidism that also received vitamin E injections.

Over the course of 42 days, we monitored various health markers in these groups. The hypothyroid rats showed a significant drop in important substances like serum thyroxin, which is critical for thyroid function. We also noted an increase in harmful compounds while protective enzyme activities plummeted in their liver and kidney tissues.

Interestingly, vitamin E appeared to reverse some of this damage. It raised the levels of important antioxidants and reduced harmful substances in the tissues of rats receiving it. Not only did we observe improvements in blood markers like alanine aminotransferase (ALT) and blood urea nitrogen (BUN), but albumin levels also increased, indicating a healthier state of the liver and kidneys.

Overall, our findings suggest that vitamin E has a protective role against liver and kidney damage in hypothyroid rats, potentially offering a beneficial adjunct therapy for thyroid-related health issues.
8.8
Supports skin health
Most Useful Review
Excellent product, I take it alongside collagen. The quantity is just right, and the pills are easy to swallow. It has proven beneficial for my skin, and my doctor recommended it to support my treatment for hypothyroidism.

Tinnitus

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
8.8
Improved tinnitus symptoms
Most Useful Review
Vitamin E helped my high platelet count return to normal, and I feel it changed my blood from thick to smooth. Remarkably, my long-term tinnitus has improved. The size is easy to consume and there's no distinct taste. If you're seeking vitamin E, I recommend this one.

Hair Loss

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Effective for hair loss
Most Useful Review
I take this daily after experiencing hair loss from Covid. It works remarkably well, and I won’t be switching to another brand again!

Autoimmune Disorder

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
6.8
Cold symptoms reduced
Most Useful Review
I've suffered from being cold since childhood. I've started taking the fat-soluble vitamin weekly, gradually increasing the dosage. I noticed I'm warmer now, but it’s still an issue in spring. I plan to order again once I've finished this batch.

Cardiovascular Disease

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 19 Reviews
8.4
9.5
Reproductive health
Most Useful Review
Vitamin E is vital for cellular protection against damage from free radicals, strengthens immunity, promotes blood vessel health, and reduces thrombus formation. It assists in reproductive health and can alleviate symptoms related to cardiovascular disease and menopause.

Headache

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 30 Reviews
8.4
7.5
Headache improvement
Most Useful Review
Drinking vitamin E has noticeably improved my headaches. After starting various supplements, my headaches, which used to make me feel lethargic, have almost disappeared. I intend to keep taking it, as I really feel the benefits.

Heart Disease

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 18 Reviews
8.4
8.8
Helps heart health
Most Useful Review
The most valuable vitamin! Vitamin E, at 400 IU daily, significantly protects against heart disease. It improves blood circulation and cleanses blood of harmful fats, thus naturally thinning it without toxicity. Vitamin E is crucial for protein synthesis and metabolic processes. I take it with omega acids to enhance absorption and help prevent wrinkles.

Menopause

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 17 Reviews
8.4
8
Vitamin E enhances vaginal health
Retrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.
Most Relevant Research
We examined how tocopherol acetate, commonly known as vitamin E, affects vaginal health in women experiencing menopause and those who are premenopausal. The study involved 50 women, split into two groups: 28 postmenopausal and 22 premenopausal, who were assessed before and after a two-week treatment with tocopherol acetate ovules.

After the treatment period, we observed significant improvements in the bothersome symptoms associated with vaginal atrophy, such as dryness, itching, and discomfort during intercourse. Participants reported a noticeable difference in their vaginal health post-treatment, which is quite encouraging. Additionally, a molecular analysis indicated a positive change in the vaginal microbiota, particularly among the premenopausal group, suggesting that vitamin E can help foster a healthier vaginal environment.

Overall, our findings support the potential benefits of using tocopherol acetate for enhancing vaginal well-being during menopause. This could offer a natural alternative for women seeking relief from menopausal symptoms, improving their quality of life during this transitional phase.
9.5
Cyst reduction
Most Useful Review
Vitamin E has rejuvenating properties. During menopause, I took it consistently and managed to eliminate two ovarian cysts with this product.

Sleep Apnea

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
8.3
Better sleep quality
Most Useful Review
The quality is excellent. I initially hesitated to apply it directly to my face due to concerns, but the small capsule is easy to use. I noticed an improvement in my sleep, which I believe has helped with my sleep apnea.

Chronic Fatigue Syndrome

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.2
7.5
Mixed results
Most Useful Review
Initially, I didn’t notice much change from vitamin E and various supplements, leading to frustration due to managing chronic fatigue syndrome. However, switching to a multivitamin + α produced surprising results, improving my overall fatigue and skin issues.
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