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Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
83 mg (20 billion CFUs)
**
Inulin (Chicory root extract)
200 mg
**
The product is found useful for the following medical conditions
Eczema
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
8
Lactobacillus rhamnosus reduces eczema risk
Differential modification of genetic susceptibility to childhood eczema by two probiotics.
Most Relevant Research
We examined the effects of Lactobacillus rhamnosus HN001 on eczema prevention among children with genetic predispositions. In our double-blind, randomized, placebo-controlled study involving 331 children, we discovered that those with specific high-risk gene variants experienced lower eczema rates when treated with HN001, compared to those receiving a placebo. This suggests Lactobacillus rhamnosus might be particularly beneficial for children at greater genetic risk of eczema and may even influence the severity of eczema and related allergic conditions.
9.5
Cured my eczema
Most Useful Review
The best probiotic! It has significantly helped me eliminate my chronic eczema.
Food Poisoning
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Lacticaseibacillus rhamnosus shows promise
In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.
Most Relevant Research
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
9.5
Quick recovery noted
Most Useful Review
One of the best probiotics! Summer is the season for holidays, street food, and fruits, leading to food poisoning and dysbacteriosis. This effective product restores gut flora and halts diarrhoea. The capsule size is convenient, and you can open it and mix it with water. It can be a dietary supplement. The packaging is lovely, and I appreciate the quick effects – I noticed improvement within 24 hours.
Allergies
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Lactobacillus rhamnosus DNA affects allergies
Probiotic DNA regulates intestinal Th2 polarization by inducing epithelial cells to produce PD-L1.
Most Relevant Research
We explored how Lactobacillus rhamnosus DNA might affect allergic responses linked to Th2 polarization. Using a specific protocol in mice, we administered LR-DNA daily for five days and observed its impact on intestinal cells. The results showed that LR-DNA increased PD-L1 expression in these cells, which then helped trigger the death of Th2 cells.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
8.8
Milk allergy relief
Most Useful Review
Very good probiotic for patients with milk allergies, as advised by my doctor.
Psoriasis
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 1 Review
8.6
8
Probiotics show positive psoriasis effects
The Role of Probiotics as an Adjunctive Therapy in Psoriasis.
Most Relevant Research
We evaluated the impact of Lactobacillus rhamnosus on psoriasis by conducting a study with 35 patients split into two groups: one received probiotics while the other got a placebo.
After 60 days, we observed that those taking probiotics showed significant improvements in clinical symptoms, reflected in various assessment scores like PASI, BSA, and DLQI.
However, it’s important to note that this improvement was not linked to any decrease in inflammation markers, IL17 and IL23. Overall, we found probiotics to be a promising adjunctive therapy for psoriasis, with minimal side effects reported.
After 60 days, we observed that those taking probiotics showed significant improvements in clinical symptoms, reflected in various assessment scores like PASI, BSA, and DLQI.
However, it’s important to note that this improvement was not linked to any decrease in inflammation markers, IL17 and IL23. Overall, we found probiotics to be a promising adjunctive therapy for psoriasis, with minimal side effects reported.
9.5
Psoriasis control
Most Useful Review
Excellent! I used this to manage my psoriasis and didn't experience any flare-ups while taking it.
Urinary Tract Infection
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.2
USERS' SCORE
Good
Based on 1 Review
8.6
8
Probiotic catheters may prevent CAUTIs
3D-Bioprinted Urinary Catheters Enable Sustained Probiotic Recovery Under Flow and Improve Bladder Colonization In Vivo.
Most Relevant Research
We explored the use of 3D bioprinted catheters to deliver Lactobacillus rhamnosus as a potential preventative measure against catheter-associated urinary tract infections (CAUTIs). In our assessment, the bioprints successfully supported the growth and viability of L. rhamnosus under simulated urine flow conditions. Remarkably, this probiotic managed to colonize the bladder without causing tissue inflammation.
Our findings suggest that these bioprinted probiotic catheters could be a promising new approach to help combat CAUTIs, offering a safe and effective strategy to reduce pathogen colonization in urinary catheters.
Our findings suggest that these bioprinted probiotic catheters could be a promising new approach to help combat CAUTIs, offering a safe and effective strategy to reduce pathogen colonization in urinary catheters.
9.5
Effective treatment
Most Useful Review
Works remarkably well for yeast infections. This is the best probiotic I’ve ever used for addressing my urinary tract infection.
Yeast Infection
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.3
USERS' SCORE
Good
Based on 1 Review
8.6
9
Lactobacillus rhamnosus shows promise
Lactobacillus rhamnosus intake can prevent the development of Candidiasis.
Most Relevant Research
This study examined how Lactobacillus rhamnosus could impact the development of yeast infections, specifically candidiasis. By using immunosuppressed mice, we created various groups to see if taking this probiotic before or during Candida exposure made a difference.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
10
Effective treatment
Most Useful Review
Very good! It works exceptionally well for yeast infections. This is the best probiotic I’ve ever used for treating a yeast infection.
Colitis
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Rapid recovery
Most Useful Review
They work without side effects! We have a family member with Ulcerative Colitis, and these genuinely helped during his major flare-up, significantly reducing recovery time. Recently, I suffered stomach issues and resumed taking these nightly. Within a day, I felt much better and have continuously improved since. I repurchased and will keep doing so.
Ulcer
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.6
USERS' SCORE
Good
Based on 1 Review
8.6
9
Inulin alleviates ulcerative colitis
An inulin-type fructan CP-A from alleviates TNBS-induced ulcerative colitis based on serum-untargeted metabolomics.
Most Relevant Research
We investigated how inulin-type fructan CP-A, a key component found in certain polysaccharides, influences ulcerative colitis (UC), an inflammatory disease marked by symptoms like abdominal pain, diarrhea, and bloody stools. To conduct this research, we used a rat model treated with 2,4,6-trinitrobenzene sulfonic acid (TNBS) to simulate UC and an in vitro model with colonic epithelial cells exposed to lipopolysaccharides (LPS) to better understand the cellular response.
Through our experiments, we discovered that CP-A significantly lessens colonic injuries and reduces markers associated with inflammation, such as interleukin-8 and tumor necrosis factor-alpha. Furthermore, we observed improvements in levels of protective substances like interleukin-10 and transforming growth factor-beta after treatment with CP-A. In our in vitro tests, CP-A effectively lowered nitric oxide and interleukin-1 beta production following LPS stimulation, indicating a reduction in inflammatory responses.
Our metabolic analysis revealed a connection between CP-A therapy and the mammalian target of rapamycin (mTOR) signaling pathway. Both in vivo and in vitro validations suggested that this pathway plays a critical role in CP-A's ability to alleviate UC by inhibiting inflammation-related signaling mechanisms. These findings can pave the way for new treatment approaches for patients suffering from ulcerative colitis, suggesting that inulin-type fructan CP-A holds therapeutic promise in managing and potentially improving this challenging condition.
Through our experiments, we discovered that CP-A significantly lessens colonic injuries and reduces markers associated with inflammation, such as interleukin-8 and tumor necrosis factor-alpha. Furthermore, we observed improvements in levels of protective substances like interleukin-10 and transforming growth factor-beta after treatment with CP-A. In our in vitro tests, CP-A effectively lowered nitric oxide and interleukin-1 beta production following LPS stimulation, indicating a reduction in inflammatory responses.
Our metabolic analysis revealed a connection between CP-A therapy and the mammalian target of rapamycin (mTOR) signaling pathway. Both in vivo and in vitro validations suggested that this pathway plays a critical role in CP-A's ability to alleviate UC by inhibiting inflammation-related signaling mechanisms. These findings can pave the way for new treatment approaches for patients suffering from ulcerative colitis, suggesting that inulin-type fructan CP-A holds therapeutic promise in managing and potentially improving this challenging condition.
9.5
Speeds healing process
Most Useful Review
They truly work! My family member has ulcerative colitis, and these probiotics have significantly aided him during a severe flare-up, reducing the healing time. In January 2023, I experienced stomach issues, but after taking them for one night, I felt 50% better by morning. I've since repurchased and stay consistent with them.
Anxiety
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.7
USERS' SCORE
Good
Based on 1 Review
8.5
8
Lactobacillus JB-1 reduces anxiety
Continuous Ingestion of JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats.
Most Relevant Research
We explored how the treatment with JB-1—a type of probiotic bacteria—affects anxiety during chronic stress in rats. In our study, half of the twenty rats received JB-1 while the other half got a placebo over eight weeks of stress exposure.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.
This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
8.8
Anxiety relief
Most Useful Review
It’s true that this product is pricey, but it’s invaluable, especially for those with digestive issues. After my sleeve gastrectomy ten years ago, I suffered from gas and colic when I drank coffee with milk. Taking Riha Takramun on an empty stomach made a significant difference; it eased my stomach discomfort and improved my psychological state. My anxiety diminished as well, although I’m unsure if it’s directly related. Consider exploring holistic medicine, which discusses the importance of resting the intestines and its impact on mental health.
Bloating
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.7
USERS' SCORE
Good
Based on 13 Reviews
8.5
8
L. rhamnosus may reduce bloating
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
Most Relevant Research
We focused on how Lacticaseibacillus rhamnosus IDCC 3201 affects bloating in people with irritable bowel syndrome with constipation (IBS-C).
In a randomized, double-blind, placebo-controlled trial involving 30 participants, those taking the probiotic experienced significant improvements.
After 8 weeks, symptoms like abdominal bloating and bowel satisfaction notably improved in the probiotic group compared to those on placebo.
This suggests that RH 3201 may enhance gut health by boosting beneficial bacteria and associated metabolites.
In a randomized, double-blind, placebo-controlled trial involving 30 participants, those taking the probiotic experienced significant improvements.
After 8 weeks, symptoms like abdominal bloating and bowel satisfaction notably improved in the probiotic group compared to those on placebo.
This suggests that RH 3201 may enhance gut health by boosting beneficial bacteria and associated metabolites.
9.5
Bloating resolved
Most Useful Review
These are truly remarkable! After years of visiting doctors for my stomach issues, I finally tried these probiotics and my digestive system has never felt better. If you're struggling with bloating, stomach cramps, or irregular bowel movements, do consider this product.
Chest Pain
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Probiotics prevent antibiotic-related diarrhea
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.
Most Relevant Research
We examined how probiotics, particularly Lactobacillus rhamnosus, could help prevent antibiotic-associated diarrhea (AAD) in children. Through a review of 23 studies involving nearly 4,000 participants, we found that probiotics significantly reduced the incidence of diarrhea—8% in the probiotic group compared to 19% in the control group.
Importantly, we noted very few adverse events, emphasizing that probiotics appear safe as a preventative option. While current data is encouraging, further research is necessary before making broad recommendations for all pediatric patients.
Importantly, we noted very few adverse events, emphasizing that probiotics appear safe as a preventative option. While current data is encouraging, further research is necessary before making broad recommendations for all pediatric patients.
9.5
Stomach pain relief
Most Useful Review
The child drinks after antibiotics and has become regular, with no discomfort, and the stomach pain has disappeared.
Cold Sores
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Alleviates discomfort
Most Useful Review
I purchased these lozenges for myself after previously taking zinc in picolinate form. I found them to be quite enjoyable and soothing for my throat. Unlike other pharmaceutical preparations, these lozenges didn’t make me feel nauseous even when taken. I take them every two hours at the onset of a sore throat, and they significantly alleviate the discomfort associated with cold sores. I highly recommend them!
Constipation
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.8
USERS' SCORE
Good
Based on 14 Reviews
8.5
9
Probiotic improves IBS-C symptoms
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
Most Relevant Research
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
9.5
Eliminated constipation
Most Useful Review
An excellent probiotic; I bought it for the first time and am very satisfied. It effectively addressed my issues, and after taking one capsule at night, my stool improved immediately, constipation disappeared, and abdominal distension went away. This is essentially a SYNbiotic, as it contains I. rhamnosus and inulin. I recommend following a probiotic course of 1-2 months.
Diarrhea
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.6
USERS' SCORE
Good
Based on 7 Reviews
8.5
9.5
Inulin reduces neonatal diarrhea incidence
Dietary Inulin Regulated Gut Microbiota and Improved Neonatal Health in a Pregnant Sow Model.
Most Relevant Research
We explored the effect of inulin, a type of dietary fiber, on the health of piglets born to sows during pregnancy. In our study, multiparous sows were divided into two groups. One group received a diet without inulin, while the other group was fed a diet containing 1.6% inulin.
We observed that the inclusion of inulin in the diet significantly reduced the incidences of diarrhea in piglets. Specifically, the sows that consumed inulin had lower levels of urea nitrogen in their colostrum, which correlated with better health outcomes for their piglets. This led to increased survival rates and overall growth of the piglets, providing encouraging evidence that inulin can play an important role in enhancing neonatal health.
Overall, our findings suggest that maternal dietary fiber, particularly inulin, not only supports the health of the sows but also positively influences the wellbeing of their offspring, notably in reducing the risk of diarrhea in newborn piglets.
We observed that the inclusion of inulin in the diet significantly reduced the incidences of diarrhea in piglets. Specifically, the sows that consumed inulin had lower levels of urea nitrogen in their colostrum, which correlated with better health outcomes for their piglets. This led to increased survival rates and overall growth of the piglets, providing encouraging evidence that inulin can play an important role in enhancing neonatal health.
Overall, our findings suggest that maternal dietary fiber, particularly inulin, not only supports the health of the sows but also positively influences the wellbeing of their offspring, notably in reducing the risk of diarrhea in newborn piglets.
9.5
Effective for diarrhea.
Most Useful Review
Doctor Recommended Culturelle for chronic diarrhoea. It appears to work remarkably well for me.
Pelvic Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9.5
Relieved discomfort
Most Useful Review
After taking antibiotics, my child has begun to drink regularly without any discomfort, and the pelvic pain has completely resolved.
Cdiff
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Good value for IBS
Most Useful Review
Best value and effective. I have tried many probiotics, and this is the main one that aids my IBS. I began using it after a hospital stay and a bout with cdiff. I use this daily to maintain a happy tummy. I don't always eat well, and I can tell when I skip my probiotic. I ensure I take it whenever I'm on antibiotics.
Thrush
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Minimal thrush issues
Most Useful Review
After 3 weeks of antibiotics, I experienced no thrush! Previously, taking levofloxacin resulted in esophageal thrush, but with this product, I only had a mild case of oral thrush, which cleared up within days with no extra medication.
Irritable Bowel Syndrome
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Effective treatment for IBS-C
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
Most Relevant Research
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
8.8
Improved bowel function
Most Useful Review
Great probiotics! I noticed an improvement in my bowel function after using antibiotics. I'm satisfied!
Autoimmune Disorder
SCIENTIFIC SCORE
Moderately Effective
Based on 28 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.1
9
LC-STH-13 counters lupus effects
LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway.
Most Relevant Research
We explored the effects of probiotic LC-STH-13 on systemic lupus erythematosus (SLE) in MRL/lpr mice. Our study demonstrated that LC-STH-13 significantly decreased harmful autoantibodies and rebalanced specific immune cells.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
8.3
Improved digestion
Most Useful Review
Good probiotics—my bowel movements improved, and my stomach no longer felt bloated. I was pleased with the results and will order again.
