Doctor&#039;s Best High Absorption Magnesium Lysinate Glycinate

Magnesium supplementation aids chest pain

Based on 5 Researches

The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy.

Most Relevant Research

We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.

9.5

Saved my life

Most Useful Review

Definitely saved me! After taking a high dose of vitamin D, my magnesium levels were depleted. I experienced severe symptoms, including exhaustion and chest pain. Once I read that vitamin D needs magnesium to become active, I sought magnesium supplements. After trying different types, this one made a significant difference in just a few days! My heart rate improved from 81-78 to 70-67 while resting. If you have heart issues, consider this with vitamin C; it might just save your life.

Headache

Magnesium aids migraine management

Based on 7 Researches

Magnesium and Migraine.

Most Relevant Research

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.

9.5

Relieves headaches

Most Useful Review

Magnesium chelate is fantastic! Its powder form allows quick absorption without digestive issues. My sleep improves significantly, and it effectively alleviates headaches, muscle pain, and stress. I find it much better than other types of magnesium.

Heart Attack

Magnesium implantation improves heart recovery

Questionable

Based on 14 Researches

Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.

Most Relevant Research

We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.

9.5

Saved from heart attack

Most Useful Review

This product truly saved me! After taking a mega dose of vitamin D, I experienced terrifying symptoms such as leg and neck pain, exhaustion, and heart pain which felt like a heart attack. I discovered that vitamin D requires magnesium to activate, so I tried various magnesium supplements with little success. However, this product made a noticeable difference within days, reducing my heart rate significantly. If you have heart issues, combined with vitamin C, it could save your life like it did mine. The taste is awful, but it's worth it!

Heart Disease

I ordered this for myself. I have no complaints; it's as described. The powder dissolves easily in warm water and is well-absorbed due to the chelation with amino acids. It helps with my nervous system and muscles, allowing for good sleep. I prefer this powder over encapsulated forms, as it’s effective and supports my magnesium levels, crucial for heart disease.

Insomnia

Magnesium improves elderly insomnia

Based on 11 Researches

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.

Most Relevant Research

We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.

8.3

Wonders for sleep

Most Useful Review

It works well for restlessness at night. Insomnia runs in my family, and I typically struggle to fall asleep and stay asleep. I’ve tried other magnesium supplements; they usually make me feel ill or don’t work. This one has worked wonders—by evening, I'm already feeling tired. However, I'm still working on the issue of waking up, especially with my special needs dog, but it's been a relief for falling asleep.

Knee Pain

Great product! I've found the powder a bit hard to swallow with water, but I'm getting used to it. It seems to help reduce my reliance on painkillers for my knee pain caused by osteoarthritis. Thank you.

Dizziness

Magnesium's role in Meniere's treatment

Based on 6 Researches

Successful treatment of a child with definite Meniere's disease with the migraine regimen.

Most Relevant Research

We observed the intriguing connection between Meniere's disease (MD) and migraine-related dizziness in our study of a 5-year-old girl. She experienced a six-month struggle with left-sided hearing loss, which evolved into daily bouts of vertigo, headaches, and vomiting, fulfilling the criteria for definite MD.

After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.

This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.

9.5

Improved balance

Most Useful Review

Resolves issues with insomnia, dizziness, and tinnitus. After taking two tablets of High Absorption Magnesium, I felt calm and relaxed. I have Meniere's disease, which has affected my balance for 31 years. However, since taking this supplement, my balance has improved and my dizziness has subsided. Additionally, my blood pressure has improved and my hearing has also benefited. I checked side effects at the Mayo Clinic and found them to be rare. Those with kidney issues should exercise caution, as should individuals on medication, but otherwise, this supplement seems safe.

Nausea

Magnesium effectively reduces PONV

Based on 4 Researches

Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial.

Most Relevant Research

We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.

We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.

Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.

This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.

9.5

Anxiety reduced

Most Useful Review

Eliminated my general anxiety. I rarely write reviews, but I can't emphasise the difference these magnesium capsules have made! As someone who naturally deals with anxiety, experiencing chest pain and nausea daily, after taking these for about 6 weeks, I noticed a significant reduction in my usual chest pain during my morning commute. It’s been quite life-changing and I can’t believe how well I feel! I haven’t needed prescription anti-anxiety meds for over a month now; it’s unbelievable.

Cancer

Magnesium alloy inhibits cancer growth

Based on 5 Researches

Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer.

Most Relevant Research

We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.

In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.

Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.

With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.

8.8

Magnesium's benefits

Most Useful Review

A good form of magnesium. Magnesium is vital; many are deficient, which may affect heart disease, cancer, anxiety, and more. A highly absorbable form of magnesium is bound to amino acids, though it can be pricey. Overall, I recommend this, as Doctor's Best is a reputable brand supported by independent tests.

Leg Cramps

Magnesium oxide treats leg cramps

Likely Ineffective

Based on 16 Researches

A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.

Most Relevant Research

We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.

8.8

Effective magnesium aid

Most Useful Review

This product has been fantastic for my magnesium deficiency, helping me feel revitalised. It's great for leg cramps, but when I ran out, I felt terrible; hence, I am ordering more!

Sleep Apnea

Magnesium's role in sleep apnea

Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.

Most Relevant Research

We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

9.5

Stable mood

Most Useful Review

This magnesium is easily absorbed, and I've taken it before bed for over two years. It gives me restful nights without waking frequently, stabilising my mood effectively. I recommend it to my friends without hesitation.

Neuropathy

Magnesium's potential in neuropathy treatment

Based on 7 Researches

Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models.

Most Relevant Research

A recent study explored the connection between magnesium levels and diabetic sensorimotor polyneuropathy. We measured serum magnesium and plasma methylglyoxal levels in recently diagnosed type 2 diabetes patients—some with neuropathy and others without.

Our findings revealed that patients with neuropathy had significantly lower magnesium levels, which were inversely related to higher methylglyoxal levels. This interaction appeared to contribute to nerve dysfunction, making magnesium's role particularly interesting in the context of neuropathy.

We found that magnesium supplementation could protect nerve cells from the neurotoxic effects of methylglyoxal in laboratory models. Importantly, when magnesium was added, we observed improvements in cell health, suggesting that maintaining magnesium levels might be a promising strategy for mitigating diabetic neuropathy.

Overall, our research highlights a compelling link between magnesium deficiency and nerve damage, suggesting that addressing magnesium levels could hold the key to new treatment approaches for diabetic neuropathy and possibly other neurodegenerative conditions.

7.3

Eases severe cramping

Most Useful Review

This product really works for my peripheral neuropathy symptoms. The relief from extremely painful cramping in my feet and calves is what I value most. While it doesn't eliminate the symptoms, it reduces the intensity enough for me to relax and sleep at night. They are easy to swallow, which is important as I struggle with larger pills, and I take 4-6 nightly at a cost.

Tinnitus

Magnesium's role in tinnitus explored

Based on 6 Researches

Relationship between serum magnesium level and subjective tinnitus.

Most Relevant Research

We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.

By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.

Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.

No effect noted

Most Useful Review

The magnesium powder aligns with the description and is of good quality. The ingredients, size, and packaging, including a measuring spoon, are satisfactory. Overall, it is a useful product that does not upset my gastrointestinal tract. However, it does not alleviate my tinnitus (ringing in the ears).

Chronic Cough

Severe cough developed

Most Useful Review

I ordered magnesium for my grandfather (67 years old) based on doctors' advice for his heart and blood vessels. Unfortunately, he developed a chronic cough after two weeks of taking it, so we stopped. It may be due to the powder form; however, it was mixed with either milk or warm water. We're heading for an examination to identify the cause of the cough. I recommend consulting a therapist before use. I have previously ordered other bio-additives from this brand and found no issues with quality.

Diarrhea