Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
The product is found useful for the following medical conditions
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7
USERS' SCORE
Good
Based on 16 Reviews
8.9
8
Magnesium treats anxiety in MS
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
10
Life-changing impact
Most Useful Review
141 people found this helpful
These literally saved my life. For years, I struggled with severe anxiety and panic attacks that made it difficult to leave the house. I feared I would end up on disability. After taking these for three months, my anxiety and panic attacks have practically disappeared. I discovered I was calcium deficient, which made a world of difference in conjunction with my magnesium intake. My blood pressure has also improved significantly during stressful doctor visits. It took time, but looking back, I can see a considerable positive shift.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.6
8
This study looks into how mesoporous magnesium carbonate (MMC) can help with acne by reducing bacteria that thrive on our skin. We used a specific Gram-positive bacterium considered a common culprit in acne lesions. To ensure our results were reliable, we measured bacterial activity using a metabolic assay.
Our findings revealed that MMC exhibits a strong antibacterial effect against this acne-related bacterium. A significant factor contributing to its effectiveness is the material's alkalinity. This suggests that MMC could be developed further as a skincare ingredient aimed at inhibiting bacterial growth, providing an alternative to traditional antibiotic treatments.
Overall, we see promising potential for MMC in topical applications, especially for those looking for non-antibiotic solutions to manage acne and maintain skin health.
Our findings revealed that MMC exhibits a strong antibacterial effect against this acne-related bacterium. A significant factor contributing to its effectiveness is the material's alkalinity. This suggests that MMC could be developed further as a skincare ingredient aimed at inhibiting bacterial growth, providing an alternative to traditional antibiotic treatments.
Overall, we see promising potential for MMC in topical applications, especially for those looking for non-antibiotic solutions to manage acne and maintain skin health.
10
Clearer complexion
Most Useful Review
The composition of calcium and magnesium is superb, with a good dosage that is easy to use. I highly recommend purchasing this product. After a week, the results on my nails and hair were evident; my face became clean without any redness, irritation, or acne.
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Relieves common cold
Most Useful Review
It helps a lot during a common cold.
Bruise details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Magnesium reduces bruising post-surgery
We explored the impact of magnesium sulfate (MgSO4) wet dressings on bruising and swelling following blepharoplasty, a common eyelid surgery. In our study, fifty-eight patients were evenly split between two treatments: one side received a magnesium sulfate solution, while the other was cooled with ice packs. This setup allowed us to compare the effectiveness of these two methods objectively.
Over the recovery period, we observed that the eyelid swelling was similar in both groups initially but notably reduced over time. However, by the fifth day after surgery, we found that those treated with the magnesium solution experienced significantly less swelling compared to the cooling method. Additionally, bruising—measured by both area and incidence—was also lower in the magnesium group, highlighting its effectiveness.
Interestingly, a significant majority of patients preferred the magnesium treatment over ice cooling, with many appreciating the convenience and results of the wet dressing. This suggests that magnesium sulfate is not only effective in reducing bruising and swelling but is also a patient-favored option for recovery after eyelid surgery.
Over the recovery period, we observed that the eyelid swelling was similar in both groups initially but notably reduced over time. However, by the fifth day after surgery, we found that those treated with the magnesium solution experienced significantly less swelling compared to the cooling method. Additionally, bruising—measured by both area and incidence—was also lower in the magnesium group, highlighting its effectiveness.
Interestingly, a significant majority of patients preferred the magnesium treatment over ice cooling, with many appreciating the convenience and results of the wet dressing. This suggests that magnesium sulfate is not only effective in reducing bruising and swelling but is also a patient-favored option for recovery after eyelid surgery.
7.5
Quick bruise recovery
Most Useful Review
1 people found this helpful
As a nursing mother, I lack calcium, which first affects my teeth, causing sensitivity. Since taking these vitamins, this issue has been resolved; my teeth remain intact without needing any healing. Last winter, I suffered a severe bruise that damaged my ligaments and joints but thankfully not a fracture. I believe my recovery was quite fast, and that's thanks to these vitamins.
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 24 Researches
6.7
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
9
Reduced heart issues
Most Useful Review
6 people found this helpful
I found this magnesium very effective. I had a severe deficiency, which led to cramps and spasms, including my heart, causing it to beat irregularly. After the first pill, I noticed immediate peace, and my heartbeat improved significantly. Within three to four days, all deficiency symptoms vanished. The only downside is the large tablets, which can be difficult to take.
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
9
Convenient combination
Most Useful Review
1 people found this helpful
Excellent! When taking calcium, it's not absorbed effectively unless magnesium is included, making this combination very convenient. I highly recommend it for women.
Hyperthyroidism details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Better bone density
Most Useful Review
Due to my hyperthyroidism, I am more susceptible to osteoporosis and dislike sunbathing. My bone density was -3.5 in May and improved to -1.9 in September, which made me very pleased.
Leg Cramps details
SCIENTIFIC SCORE
Likely Ineffective
Based on 21 Researches
4.9
USERS' SCORE
Good
Based on 73 Reviews
8.5
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
9
Leg cramps gone
Most Useful Review
318 people found this helpful
The doctor prescribed calcium alongside magnesium, and my leg cramps have disappeared.
Reflux details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.2
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
9
Significant reflux relief
Most Useful Review
The cooling vitamins arrived extremely quickly, even faster than expected. The quality is fantastic and the packaging perfect! The taste is almost non-existent. However, the tablet contains two doses; if you need to take two per day, remember to break the pill in half. I found that after taking calcium and vitamin D, my digestion improved significantly. Endless heartburn began to fade and the frequency of reflux attacks was greatly reduced. My pancreas feels much better, and of course, my bones and immunity are in order!
Tinnitus details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
10
Tinnitus improvement observed
Most Useful Review
My tinnitus improved after taking magnesium, which I purchased for this purpose. Since I've been consistently taking it, my tinnitus has disappeared.
Toothache details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
Calcium treatment shows comparable results
We compared two root canal-filling materials used in treating primary teeth with pulp necrosis caused by trauma. Our main focus was on the effectiveness of a calcium hydroxide-based paste versus traditional zinc oxide and eugenol cement, specifically looking at clinical and radiographic outcomes after 18 months.
In our study involving 26 children, we found that both materials demonstrated similar success rates. Clinical success included factors like the absence of pain and tooth mobility, while radiographic success was determined by the healing of tooth roots. Our results indicated that both calcium treatment and zinc oxide function well for the root canal filling in children suffering from pulp necrosis, making them suitable options.
Overall, our findings suggest that whether we use calcium hydroxide or zinc oxide, parents and dentists can expect effective outcomes when treating dental trauma in young children. Thus, both materials are viable choices for addressing toothache related to pulp issues in primary teeth.
In our study involving 26 children, we found that both materials demonstrated similar success rates. Clinical success included factors like the absence of pain and tooth mobility, while radiographic success was determined by the healing of tooth roots. Our results indicated that both calcium treatment and zinc oxide function well for the root canal filling in children suffering from pulp necrosis, making them suitable options.
Overall, our findings suggest that whether we use calcium hydroxide or zinc oxide, parents and dentists can expect effective outcomes when treating dental trauma in young children. Thus, both materials are viable choices for addressing toothache related to pulp issues in primary teeth.
9
Instant toothache relief
Most Useful Review
Excellent! I thoroughly enjoyed it. It provided effective relief from my toothache.
Chest Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.4
8
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
9
Incredible pain relief
Most Useful Review
14 people found this helpful
Very effective calcium! After trying various pharmaceutical products, this calcium surprised me. After using it for a while, I experienced incredible relief from knee and hip joint pain, which had troubled me for five years. I used to limp but can now run slowly each day. I’m delighted to have forgotten about my arthritis.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 12 Reviews
8.4
8
We examined how incorporating fly ash into magnesium phosphate repair mortar (MPM) influences its effectiveness in cold environments. Our investigation revealed that fly ash modifies the microstructure of the MPM, enhancing its performance without affecting the setting time or fluidity significantly.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
9
Pain relief
Most Useful Review
2 people found this helpful
The teeth do not hurt much! These are wonderful vitamins! I have significant sensitivity of tooth enamel; I cannot drink hot, cold, or sour items. After taking these vitamins, the pain vanished, and I gained stronger nails as a bonus! Magnesium aids in the better absorption of calcium in the body. A deficiency in these elements can severely impact health. This combination of vitamins in capsules is very effective! Good dosage and filling! An excellent company, proven multiple times! I highly recommend! Please give a thumbs up; I always do! It's not hard for you, but it pleases me!
Diabetes details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.4
8
Magnesium intake benefits diabetes patients
We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
9
Reduced muscle pain
Most Useful Review
9 people found this helpful
Great product! I began taking it due to muscle pain from very low vitamin D. After a week, my muscle discomfort has nearly vanished. I feel energetic in the mornings. I also take selenium, vitamin E, D, zinc, and vitamins B and C. Magnesium is essential for diabetics; my 16-year-old daughter with type 1 diabetes takes one tablet before bed.
Frozen Shoulder details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 6 Reviews
8.4
9
We explored the effects of calcium deposition in the rotator cuff tendons on frozen shoulder, particularly in cases where calcific tendinitis was present. The study involved 32 patients who underwent a specialized procedure combining arthroscopic brisement of the shoulder joint with multiple punctures at the calcific site. This innovative approach aimed to alleviate the pain and restore mobility linked to frozen shoulder.
After following up with the patients for two years, we observed that 30 out of 32 patients reported satisfactory outcomes. While five individuals still showed some postoperative calcium deposits, many experienced significant improvements in their range of motion and relief from pain. This suggests that combining treatment methods can enhance recovery, although we recognize that the isolated effect of calcium treatment alone remains unclear.
Overall, this study contributes valuable insight into managing frozen shoulder, especially when associated with calcific tendinitis, even if it doesn't fully isolate the impact of calcium treatment.
After following up with the patients for two years, we observed that 30 out of 32 patients reported satisfactory outcomes. While five individuals still showed some postoperative calcium deposits, many experienced significant improvements in their range of motion and relief from pain. This suggests that combining treatment methods can enhance recovery, although we recognize that the isolated effect of calcium treatment alone remains unclear.
Overall, this study contributes valuable insight into managing frozen shoulder, especially when associated with calcific tendinitis, even if it doesn't fully isolate the impact of calcium treatment.
10
Shoulder pain relief
Most Useful Review
Good vitamins! The pain in my frozen shoulder has vanished, and my limbs no longer feel tight.
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.6
USERS' SCORE
Good
Based on 9 Reviews
8.4
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
10
Migraine relief
Most Useful Review
1 people found this helpful
My migraines have disappeared. I'm taking Two-Per-Day, but since it doesn't contain Cal-Mag, I'm using this as well. The migraines caused by pressure have gone. I'd like to continue taking this.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.4
10
Swelling completely removed
Most Useful Review
Essential minerals for kidney support. I take these alongside other medications and they have been highly effective; the swelling has entirely vanished.
Arteriosclerosis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Supports bone health
Most Useful Review
12 people found this helpful
This supplement delivers great doses of calcium and magnesium, which are essential for our daily intake. Most supplements cannot meet the required amounts due to their size, so taking just one of these pills is advisable even if I use another multivitamin. For optimal bone health, combining calcium with a K2 vitamin supplement, like MenaQ7, is ideal. This vitamin activates osteocalcin, which binds calcium to bones, while preventing calcium from binding to arterial walls, thereby addressing arteriosclerosis. I prefer chelated minerals for better absorption but manage just fine with this supplement, taking one pill every night.
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 18 Researches
8.1
USERS' SCORE
Good
Based on 9 Reviews
8.3
8
Magnesium protects against bone erosion
We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
9
Significant pain relief
Most Useful Review
14 people found this helpful
Very effective calcium! I've previously tried pharmaceutical calcium products, but this one truly surprised me. I took it with vitamin D3 for my knee and hip joint issues stemming from a meniscus operation. After consuming half a jar, I experienced incredible relief. I used to hobble, but now I can run slowly every day. The frequent pain has vanished, and I’m delighted. Despite scepticism towards reviews like this, I’m now sharing my own. I’ve forgotten about my arthritis and took this for myself as well.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Improved foot pain
Most Useful Review
1 people found this helpful
I experienced pain in my ankles and feet in the morning. After a doctor's suggestion, I discovered I had a magnesium deficiency. I took tests, and my magnesium levels were low while calcium was borderline. I bought these vitamins to take before bed, and within a week, I felt much better. There have been no side effects from the magnesium, including loose stools.
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.3
8
Magnesium alloy inhibits cancer growth
We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
7.5
Normal health indicators
Most Useful Review
1 people found this helpful
For a friend, 60+ After cancer, a woman constantly takes some medications, the side effect of which is a decrease in bone density. The doctor recommended taking calcium in addition, along with magnesium and vitamin D3+K2 for better absorption. On control examinations, all her indicators are normal, as well as her well-being. ❤️
Celiac details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.3
9
Strong bones support
Most Useful Review
I recently purchased Now Foods Calcium Magnesium and I am thoroughly impressed with its quality and effectiveness. As someone who values their bone health, this supplement has exceeded my expectations. The combination of calcium and magnesium in this formula provides excellent support for strong bones. Since I started taking this supplement, I've noticed my bones feel stronger, and I've gained confidence in their ability to support my active lifestyle. The addition of magnesium has also promoted relaxation. This product is free from common allergens, making it suitable for individuals with dietary sensitivities.
Hypertension details
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
9
Reduced headaches
Most Useful Review
I am very satisfied with this product, and I've even ordered it for my mum as a supplement for her hypertension! Since she started, her headaches have noticeably decreased!
Rheumatoid Arthritis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Relieved symptoms
Most Useful Review
Calcium and magnesium, nothing more. Two capsules suffice for my daily needs, lasting approximately four months per package—very economical! They help my grandmother alleviate her rheumatoid arthritis. Highly recommended! If this review is helpful, please give it a thumbs up. Bless you! ♥️
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.6
USERS' SCORE
Good
Based on 3 Reviews
8.2
7
Magnesium reduces brain injury markers
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
7.5
Overall wellbeing
Most Useful Review
1 people found this helpful
The benefits of calcium and magnesium for health are immense! They ensure proper brain function, strengthen bones, improve sleep quality, lower blood pressure, and support the nervous system among others. I've noticed improvements in my teeth and nails, as well as a decrease in impulsive behaviour, leading to greater calmness in various situations. This dietary supplement truly works! In comparison with others, it offers an excellent price-to-quality ratio and suitable dosages. I wish everyone good health and longevity!
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 9 Reviews
8.2
7
We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
9
Reduced nervousness
Most Useful Review
5 people found this helpful
I highly recommend magnesium! This is my repeated purchase, and it truly helps me relax my muscles and alleviate leg cramps. I’ve suggested it to my sister and girlfriend, and they have also sworn by it. Magnesium acts as a natural anti-stress factor, reducing anxiety and fatigue, making it essential for maintaining a healthy nervous system, especially during times of stress.
Hypothyroidism details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.4
USERS' SCORE
Good
Based on 2 Reviews
8.2
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
7.5
Improving thyroid levels
Most Useful Review
On my endocrinologist's advice, I take it alongside vitamin D3 and Omega-3 for my hypothyroidism. My analyses are gradually approaching normal.
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.6
USERS' SCORE
Good
Based on 11 Reviews
8.2
9
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
9
Reduced mood swings
Most Useful Review
8 people found this helpful
I feel calmed down! These vitamins, calcium, and magnesium work well together for absorption. I take them alongside a B complex from the same brand. They calmed my nervous system significantly. My mood swings and depression linked to menopause have diminished, and my epilepsy attacks are less frequent. My hair and nails have improved too. The vitamins are of good natural quality, and the price is superb compared to local pharmacies. I recommend it, especially for women over 40.
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Good
Based on 17 Reviews
8.2
8
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
9
No more cravings
Most Useful Review
55 people found this helpful
I accept this as directed by my orthopaedic traumatologist to treat and prevent osteoporosis before and after pelvic surgery. Cramps are common during pregnancy, so calcium plus magnesium is effective. Although I consumed various calcium supplements and craved chalk, this medication restored my body's calcium levels and eliminated my desire for chalk.
Tendonitis details
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9
USERS' SCORE
Good
Based on 4 Reviews
8.2
9
We explored the benefits of acupuncture in treating shoulder calcific tendinitis, a condition where calcium deposits form in the shoulder, causing pain and restricted movement. Our focus was a 67-year-old woman who suffered from intense shoulder pain and functional limitations for six months.
To tackle her condition, she underwent 12 acupuncture sessions. These sessions were tailored to target specific meridians affected by her illness, using about 12 needles each time. We monitored her pain levels and shoulder movement throughout the treatment period, and a follow-up MRI was conducted afterward.
Remarkably, the follow-up MRI revealed that the calcific deposits had vanished, and she experienced significant pain relief, regaining mobility and independence in her daily activities. Although she reported some mild stiffness afterward, she was encouraged to continue home exercises for further improvement. Though the results are promising, we recommend more extensive studies with control groups to validate these findings further.
To tackle her condition, she underwent 12 acupuncture sessions. These sessions were tailored to target specific meridians affected by her illness, using about 12 needles each time. We monitored her pain levels and shoulder movement throughout the treatment period, and a follow-up MRI was conducted afterward.
Remarkably, the follow-up MRI revealed that the calcific deposits had vanished, and she experienced significant pain relief, regaining mobility and independence in her daily activities. Although she reported some mild stiffness afterward, she was encouraged to continue home exercises for further improvement. Though the results are promising, we recommend more extensive studies with control groups to validate these findings further.
9
Reduced twitching
Most Useful Review
This supplement replenishes the calcium and magnesium lost due to sweets. I recommend one tablet daily, as my tendons no longer twitch. Thank you so much! ❤️
Anemia details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 4 Reviews
8.1
9
We investigated how persistent hypercalcemia—elevated calcium levels—affects hemoglobin levels in kidney transplant recipients (KTRs). Through a retrospective study including 385 patients, we analyzed the trajectories of hemoglobin in those with and without hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
9
Tremors stopped
Most Useful Review
After experiencing eye tremors alongside anemia, I noticed that my eye tremors ceased after taking this supplement.
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.7
USERS' SCORE
Good
Based on 27 Reviews
8.1
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
7.5
Joint pain relief
Most Useful Review
21 people found this helpful
I took this to strengthen my bones for my mother. Joint pain has diminished, and I recommend it.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.1
8
Magnesium scaffold shows promising results
We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
9
Blood pressure stabilised
Most Useful Review
2 people found this helpful
A great mix! My wife had severe blood pressure issues until I realised our previous magnesium-calcium supplement had changed, removing calcium. After switching to Now supplements, her blood pressure returned to normal. We found iHerb offered this at a better price, so we’ll continue buying from them.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.9
USERS' SCORE
Good
Based on 6 Reviews
8.1
9
We observed a striking case involving a 76-year-old woman diagnosed with cervical cancer, who was treated with nedaplatin, a platinum-based chemotherapy drug. Shortly after starting her treatment, she experienced troubling symptoms, including numbness, dizziness, and a noticeable loss of appetite.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
9
Dizziness improved
Most Useful Review
The supplement is quite large, making it difficult to swallow. However, it allows me to take calcium and magnesium together. I've heard excessive calcium isn’t advisable, so I've opted for magnesium alone. Since starting this, my dizziness and a feeling of fuzziness have subsided, so I don’t require medication anymore. I intend to continue for my health.
Hair Loss details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 27 Reviews
8.1
9
We explored a novel approach to tackle hair loss by using a 3D multicellular micropattern that includes magnesium silicate (MS) nanomaterials. This innovative method involved carefully positioning hair follicle-related cells in a structured network along with vascular cells, all created through advanced bioprinting techniques.
The incorporation of magnesium silicate aimed to enhance both hair follicle potential and the formation of new blood vessels—factors crucial for healthy hair growth. Our findings revealed promising results, showing that this 3D micropattern with MS significantly promoted hair regrowth in models of skin tissue regeneration, including both immunodeficient mice and those with androgenetic alopecia.
Essentially, we demonstrated that integrating magnesium with a well-designed cell arrangement could lead to better hair restoration outcomes. This significant insight contributes to the ongoing search for effective treatments for hair loss, bridging biological engineering and dermatology in the process.
The incorporation of magnesium silicate aimed to enhance both hair follicle potential and the formation of new blood vessels—factors crucial for healthy hair growth. Our findings revealed promising results, showing that this 3D micropattern with MS significantly promoted hair regrowth in models of skin tissue regeneration, including both immunodeficient mice and those with androgenetic alopecia.
Essentially, we demonstrated that integrating magnesium with a well-designed cell arrangement could lead to better hair restoration outcomes. This significant insight contributes to the ongoing search for effective treatments for hair loss, bridging biological engineering and dermatology in the process.
9
Sister's improvement
Most Useful Review
The best! I purchased it for my sister, and after a month of taking it, she noticed her nails have strengthened and her hair loss has decreased. Her mood has also improved, and the taste and quality are superb.
Premenstrual Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 26 Reviews
8.1
10
Mood stabilisation
Most Useful Review
Since taking this, my PMS has vanished, and my mood remains stable throughout my cycle. My nails feel stronger, and my bones crack less often.
Stroke details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.1
9
We investigated the role of calcium in astrocytes to enhance recovery after a stroke. Focusing on a specific optogenetic tool called OptoSTIM1, we were able to selectively activate calcium channels in astrocytes. This approach allowed us to significantly elevate calcium levels in these supporting brain cells, particularly in the sensory-parietal cortex following a stroke.
Our findings revealed that this sustained calcium increase, lasting over 10 minutes, led to noticeable improvements in post-stroke recovery. By manipulating intracellular calcium levels in astrocytes, we observed a remarkable reduction in impairment caused by chronic stroke conditions.
This study highlights the potential of targeting astrocytic calcium signals as a promising strategy for enhancing stroke recovery, paving the way for new therapeutic approaches. Overall, our research suggests that calcium's role in astrocytes could be a game changer in the efforts to improve outcomes for stroke patients.
Our findings revealed that this sustained calcium increase, lasting over 10 minutes, led to noticeable improvements in post-stroke recovery. By manipulating intracellular calcium levels in astrocytes, we observed a remarkable reduction in impairment caused by chronic stroke conditions.
This study highlights the potential of targeting astrocytic calcium signals as a promising strategy for enhancing stroke recovery, paving the way for new therapeutic approaches. Overall, our research suggests that calcium's role in astrocytes could be a game changer in the efforts to improve outcomes for stroke patients.
7.5
Reduces heart attack risk
Most Useful Review
This choice has eliminated stress while addressing magnesium deficit in my body. Magnesium mitigates blood clotting, alleviates stomach cramps, and helps with acidity levels. It’s crucial for hearing acuity, involved in brain function, and necessary for the absorption of B vitamins. Additionally, it has an anti-sclerotic effect and lowers elevated blood pressure, thereby reducing the risk of heart attack and stroke by relaxing blood vessels.
Eczema details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 6 Reviews
8
5
We explored the connection between dietary calcium intake and the occurrence of eczema in adults using data from the National Health and Nutrition Examination Survey conducted in 2005-2006. Our aim was to see if there’s a relationship between how much calcium adults consume and the likelihood of developing eczema, a common skin condition.
In this observational study, we analyzed responses from 4,086 adults, of whom 266 reported having eczema. Our statistical analysis revealed an interesting pattern: we found that individuals in the third quartile of calcium intake had a significantly higher risk of eczema compared to those in the first quartile. Essentially, our results suggested that as dietary calcium intake increased, so did the prevalence of eczema—up to a certain point.
We identified an inverted U-shaped relationship between calcium intake and eczema prevalence. Specifically, an increase in calcium intake was associated with a higher occurrence of eczema until calcium levels reached a logarithmic value of 7.089. Thus, moderating calcium intake may help reduce the incidence of eczema.
These findings indicate that while calcium is essential for health, excessive consumption may not always be beneficial, particularly in relation to skin conditions like eczema. Further research is necessary to explore this relationship more deeply and determine the best levels of calcium intake for preventing eczema.
In this observational study, we analyzed responses from 4,086 adults, of whom 266 reported having eczema. Our statistical analysis revealed an interesting pattern: we found that individuals in the third quartile of calcium intake had a significantly higher risk of eczema compared to those in the first quartile. Essentially, our results suggested that as dietary calcium intake increased, so did the prevalence of eczema—up to a certain point.
We identified an inverted U-shaped relationship between calcium intake and eczema prevalence. Specifically, an increase in calcium intake was associated with a higher occurrence of eczema until calcium levels reached a logarithmic value of 7.089. Thus, moderating calcium intake may help reduce the incidence of eczema.
These findings indicate that while calcium is essential for health, excessive consumption may not always be beneficial, particularly in relation to skin conditions like eczema. Further research is necessary to explore this relationship more deeply and determine the best levels of calcium intake for preventing eczema.
9
Eczema improved dramatically
Most Useful Review
46 people found this helpful
The price-quality-dosage ratio is excellent: it lasts a long time and has a reasonable dosage, combining two vitamins in one. My husband and I have been taking them for three months. For optimal absorption, we take chlorophyll in the morning, multivitamins, omega, vitamin D3, and calcium with magnesium in the evening since magnesium and iron don't mix. After the autumn, when eczema appeared post-pregnancy and covered my body, the dermatologist noted that only vitamin D was deficient. Once I started taking the vitamins, the body atopy vanished, and my eczema became localized between my fingers. My general condition improved. I feel magnesium aids my emotional well-being, while calcium helps with my teeth and hair loss.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 32 Reviews
8
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
9
Improved sleep quality
Most Useful Review
7 people found this helpful
Wonderful calcium! I began taking this regularly due to my physician's recommendation. It has no side effects and is well absorbed, which I can tell by the improvement in my nails. After years of dealing with insomnia, I've begun to sleep better and feel calmer, possibly thanks to the magnesium. My husband and son now use it too. I've learnt calcium should be taken daily, making this a regular purchase for our health.
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.9
USERS' SCORE
Moderately Good
Based on 42 Reviews
7.9
9
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
9
Reduced cravings
Most Useful Review
55 people found this helpful
I take this as prescribed by my orthopaedic surgeon for osteoporosis management before and after pelvic surgery. It's a great remedy for the cramps common during pregnancy. After consuming other types of calcium without relief, I finally found this one. My calcium levels have improved, and the urge to eat chalk has disappeared entirely.
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 47 Reviews
7.9
7
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
7.5
Improved sleep quality
Most Useful Review
34 people found this helpful
Great help! After a week, I noticed improvements. I began falling asleep faster, and the quality of my sleep improved. My leg muscles stopped hurting. I highly recommend it for the good value; the can is very large!
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
8
Magnesium enhances postoperative recovery
We conducted a study to see how magnesium sulfate could influence recovery after total knee arthroplasty in older patients. Using a double-blind, randomized control design, 148 patients were split into two groups: one received magnesium sulfate while the other got saline.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
9
Allergy improvement
Most Useful Review
Mum is taking it, and it seems her allergies have improved.
Atrial Flutter details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
9
Effective for arrhythmia
Most Useful Review
I recommend this product! The drug is excellent, containing a substantial dosage of magnesium and calcium. It effectively helped me manage attacks of arrhythmia, which indicates good absorption. It surpasses the costly Magneroth in price-quality-dosage. To enhance the effect, consider purchasing vitamin group B. If you find it helpful, do show your appreciation!
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.5
USERS' SCORE
Moderately Good
Based on 28 Reviews
7.8
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9
Strong nails improvement
Most Useful Review
94 people found this helpful
Very high-quality calcium combined with magnesium. I’ve been using NowFoods products for a while, and this calcium to magnesium blend did not disappoint. My nails, which weren't strong naturally, became noticeably stronger and shinier. I also had issues with tooth enamel, but now I don’t feel sensitivity to acids or temperature. Magnesium has helped me manage stress, making me calmer. I confidently recommend this supplement for strengthening nails, teeth, and supporting bone health and the nervous system.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.6
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
9
Helpful but large
Most Useful Review
1 people found this helpful
I have used this product repeatedly as I suffered from chronic constipation and required magnesium. I usually consume seaweed like wakame and hijiki, but I also take supplements. However, these tablets are rather large and occasionally get stuck in my throat, perhaps due to their size and my age. It would be beneficial if they could be made smaller and allow for the intake of two tablets at a time.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Moderately Good
Based on 23 Reviews
7.5
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
9
Reduced irritability
Most Useful Review
9 people found this helpful
The magnesium helped alleviate my anxiety and irritability, making me more productive and enabling quicker sleep. I took it alongside vitamin D and omega-3, which improved my overall well-being. The dosages are individual, but I felt a notable difference once I incorporated it into my routine.
Bloating details
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
8
We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
7.5
Negative impact noted
Most Useful Review
3 people found this helpful
Contains three forms of magnesium, primarily magnesium oxide, which is deemed the least effective. The best type is magnesium citrate, though its quantity here is unknown. Uncontrolled calcium intake may lead to kidney stones, constipation, bloating, and various digestive issues. Additionally, excess calcium can hinder the absorption of vital minerals such as magnesium, zinc, and iron, leading to potential deficiencies and associated problems.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.4
8
Magnesium's impact on heart health
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
7.5
Improved bone strength
Most Useful Review
120 people found this helpful
Wonderful! Everyone knows about the benefits of calcium for teeth and bones, yet many still experience insufficient bone strength. This often occurs because calcium is not taken with magnesium. I took these vitamins during pregnancy, and they helped with cramps and maintaining healthy nails and hair. If my review is useful, please support me. I drink these vitamins regularly and recommend them to all.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.4
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
9
Heart symptoms vanish
Most Useful Review
1 people found this helpful
This magnesium supplement significantly improved my heart health; after just one to two weeks of use, symptoms of heart disease disappeared. It is well-tolerated without side effects when taken as instructed. Though the tablets are slightly large, I ordered more since women especially benefit from magnesium. I highly recommend it!
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.8
USERS' SCORE
Moderately Good
Based on 35 Reviews
7.4
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
7.5
Reduced knee pain
Most Useful Review
74 people found this helpful
Very cool! Calcium and magnesium work well together. I discovered that taking these in the evening allows for better absorption. The jar is large, and the tablets are sizeable. I've noticed significant relief; my knee pain has decreased, and osteochondrosis is less concerning. I prefer to take them in a course.
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 24 Researches
6.8
USERS' SCORE
Moderately Good
Based on 54 Reviews
7.3
9
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
9
Reduced swelling
Most Useful Review
28 people found this helpful
I have taken two tablets daily for three months, and the swelling has reduced significantly. People comment on my improved body shape; I’ve even gone down two ring sizes! My constipation has also improved, and leg cramps have disappeared. I am committed to continuing this regimen.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.3
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.2
9
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
9
Calmness achieved
Most Useful Review
12 people found this helpful
Calm improved! I began to feel much calmer, with no signs of depression. My husband is surprised by my reduced yelling. I highly recommend it.
Rash details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.3
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.2
9.5
We investigated how magnesium deficiency affects rash in hairless rats, which develop a severe, itchy rash resembling atopic dermatitis. In our study, we tested a derivative called SDZ ASM 981, given either systemically or topically. Remarkably, oral treatment with SDZ ASM 981 significantly cleared the rash within just one day.
Furthermore, this treatment reduced several inflammatory markers, showing promising results for both prevention and therapy. This indicates that magnesium's role might be crucial in managing similar skin conditions in humans, reinforcing the value of this rat model for effective treatment evaluation.
Furthermore, this treatment reduced several inflammatory markers, showing promising results for both prevention and therapy. This indicates that magnesium's role might be crucial in managing similar skin conditions in humans, reinforcing the value of this rat model for effective treatment evaluation.
9
Rash-free experience
Most Useful Review
After pregnancy and breastfeeding, my overall condition suffered significantly. I experienced a severe rash from regular pharmacy calcium, making it hard to find suitable supplements. However, these vitamins caused no negative reactions! I was immensely pleased, as it implied no additives in the composition. I began to sleep better and felt generally revitalised. My apathy and insomnia vanished. I noticed the magnesium's effect within a week of starting. I took the complex while breastfeeding, with no adverse effects on my baby. Highly recommend, especially post-pregnancy. The tablets are large, so I chew them; they taste like regular calcium.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.6
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.1
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
7.5
Reduced headaches
Most Useful Review
11 people found this helpful
The doctor identified my lack of calcium and magnesium. After two weeks of taking these supplements, I noticed that the pain in my joints due to the weather and my headaches had lessened significantly. It’s important to use them purposefully, as overdosing can lead to poor reviews. One capsule a day lasts a long time with the sizeable container!
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Medium or Average
Based on 14 Reviews
6.9
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
9
No nausea felt
Most Useful Review
2 people found this helpful
Calcium & Magnesium is not an overly expensive dietary supplement. Its affordability is justified: one of the components sufficiently compensates for all existing deficiencies. Despite their large size, I find the pills easy to swallow. After taking each pill, I attentively listened to my stomach for nausea, but fortunately, I never felt sick during the entire month.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 9 Reviews
6.4
9
Effective bowel movement
Most Useful Review
2 people found this helpful
I didn't get along well, so I purchased this after seeing an advertisement stating "Smooth with magnesium". The supplement is rather large and can catch in the throat if not swallowed correctly, so one must take care. However, within a week, my bowel movements became quite smooth, alleviating my constipation. Despite the size, it has genuinely helped me.
