We investigated how persistent hypercalcemia—elevated calcium levels—affects hemoglobin levels in kidney transplant recipients (KTRs). Through a retrospective study including 385 patients, we analyzed the trajectories of hemoglobin in those with and without hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
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Most Useful Reviews
9
Tremors stopped
After experiencing eye tremors alongside anemia, I noticed that my eye tremors ceased after taking this supplement.
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8
Condition improved
I took it when symptoms of anemia appeared and completed the course; my condition improved. I love this brand and would recommend it.
Read More
6
Good for anemia
I trust Now Foods for their quality products. The magnesium dosage of 500 mg exceeds a prophylactic dose, which is beneficial for anemia. While the calcium dosage is slightly below the recommended amount, calcium primarily comes from food, making it not detrimental to health.
We investigated how persistent hypercalcemia—elevated calcium levels—affects hemoglobin levels in kidney transplant recipients (KTRs). Through a retrospective study including 385 patients, we analyzed the trajectories of hemoglobin in those with and without hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Tremors stopped
After experiencing eye tremors alongside anemia, I noticed that my eye tremors ceased after taking this supplement.
Read More
8
Condition improved
I took it when symptoms of anemia appeared and completed the course; my condition improved. I love this brand and would recommend it.
Read More
6
Good for anemia
I trust Now Foods for their quality products. The magnesium dosage of 500 mg exceeds a prophylactic dose, which is beneficial for anemia. While the calcium dosage is slightly below the recommended amount, calcium primarily comes from food, making it not detrimental to health.
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5
Hope for improvement
I purchased it to combat fatigue and anemia. The pills are rather large, which is somewhat burdensome, but I bought them primarily to supplement calcium. I hope it helps improve my fatigue and anemia with consistent use.
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Frequently Asked Questions
Anemia is a medical condition characterized by a deficiency of red blood cells or hemoglobin in the blood, which can result in reduced oxygen flow to the body's organs. The most common type of anemia is iron-deficiency anemia, which occurs when the body does not have enough iron to produce adequate hemoglobin. Other types can arise from chronic diseases, genetic conditions, or a lack of certain vitamins such as B12 or folate. Symptoms often include fatigue, weakness, pale skin, and shortness of breath, particularly during physical activity.
Diagnosing anemia typically involves blood tests to measure levels of red blood cells, hemoglobin concentration, and other related factors. Treatment varies depending on the underlying cause but may include dietary changes, supplements, or medications. In some cases, more serious interventions may be necessary, such as blood transfusions or treatments for associated conditions. If you suspect you have anemia, it's essential to consult a healthcare professional for appropriate evaluation and management.
Calcium magnesium refers to a dietary supplement that combines two essential minerals, calcium and magnesium, which play critical roles in maintaining various bodily functions. Calcium is vital for building and maintaining strong bones and teeth, while magnesium supports muscle function, energy production, and the regulation of calcium levels in the body. Together, these minerals work synergistically to promote overall health, particularly in areas such as bone density, cardiovascular health, and muscle function.
Supplements that contain both calcium and magnesium can be particularly beneficial for individuals who may be deficient in these minerals due to dietary restrictions or health conditions. They are available in various forms, including tablets, capsules, and powders. When considering a calcium magnesium supplement, it's essential to choose a product with the right ratio of these minerals, as well as other supporting vitamins and minerals like vitamin D, which enhances calcium absorption. Always consult with a healthcare provider before starting any new supplement regimen to ensure it aligns with your health needs and goals.
Based on user reviews, the timeframe for seeing results from taking this supplement for anemia can vary. Some users report noticeable improvements in their symptoms relatively quickly. For instance, one user observed an improvement in their condition after completing the entire course of the supplement, indicating a positive effect from consistent use Read Review. Another user mentioned that associated symptoms, such as eye tremors, ceased after starting the supplement, suggesting that benefits may be seen within a short period if specific symptoms are closely related Read Review.
However, it’s important to note that individual experiences may differ, and consistency in usage appears to be key. One reviewer emphasized their hope for improvements in fatigue and anemia symptoms with ongoing use of the product, illustrating that some users may expect to see benefits over a longer timeframe, particularly if they are addressing their condition gradually Read Review. In summary, while some users report quick improvements, a consistent regimen is likely necessary for others.
Users report a range of improvements in their symptoms after taking the supplement aimed at addressing anemia. One reviewer noted a significant improvement in their condition after completing the course, demonstrating the potential effectiveness of this product Read Review. Additionally, another user experienced a cessation of eye tremors that had accompanied their anemia, indicating that users may notice rapid relief from specific symptoms shortly after starting the supplement Read Review.
Furthermore, some users express hope for gradual improvement, citing the importance of consistent use. One reviewer, while noting the size of the pills as a drawback, remains optimistic about combating fatigue and anemia over time with ongoing supplementation Read Review. As with any health supplement, results can vary, but many customers seem to find solace in the product's potential to support their journey towards better health.
Users report varying experiences when it comes to combining this supplement with others while addressing anemia. One user specifically mentioned that the magnesium dosage in the supplement exceeded prophylactic levels, which they found beneficial for anemia, suggesting that pairing it with calcium from food could enhance effectiveness Read Review. This implies a potential synergy between magnesium and other nutrients that could potentially support anemia management.
Another reviewer noted their primary purchase of the supplement was to supplement calcium, indicating an intention to use it in conjunction with addressing fatigue and anemia. They expressed optimism that consistent use would yield improvements, demonstrating that users might be experimenting with multiple supplements to tackle their symptoms effectively Read Review. Overall, while reports of specific combinations are limited, users seem to approach their anemia treatment with a willingness to explore various nutritional aids.
Based on user reviews, the consensus around the appropriate dose of Calcium Magnesium for treating anemia appears to vary but leans towards higher magnesium levels. One user noted that a magnesium dosage of 500 mg is beneficial for anemia, even though the calcium amount is slightly below the recommended levels. This suggests that an increased magnesium intake may play a significant role in alleviating symptoms of anemia, as indicated by their experience with the product Read Review.
Other users shared varying perspectives on their experiences with the supplement. One user remarked that they noticed improvements in their anemia symptoms after completing their course, while another experienced a cessation of eye tremors, hinting at possible interconnected benefits of the supplement to overall health Read ReviewRead Review. Ultimately, while users report positive effects, the right dose may depend on individual needs, with a focus on ensuring sufficient magnesium intake to support anemia management.
8
Condition improved
I took it when symptoms of anemia appeared and completed the course; my condition improved. I love this brand and would recommend it.
9
Tremors stopped
After experiencing eye tremors alongside anemia, I noticed that my eye tremors ceased after taking this supplement.
5
Hope for improvement
I purchased it to combat fatigue and anemia. The pills are rather large, which is somewhat burdensome, but I bought them primarily to supplement calcium. I hope it helps improve my fatigue and anemia with consistent use.
6
Good for anemia
I trust Now Foods for their quality products. The magnesium dosage of 500 mg exceeds a prophylactic dose, which is beneficial for anemia. While the calcium dosage is slightly below the recommended amount, calcium primarily comes from food, making it not detrimental to health.
References
Cojuc-Konigsberg G, Gindl-Bracho A, Linares-Pérez CE, Albarrán-Muñoz S, Reul-Linares E, et al. Effect of persistent hypercalcemia on hemoglobin levels after kidney transplantation. Clin Nephrol. 2025. 10.5414/CN111553