Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (from Thiamin HCl) (Vitamin B-1)
100 mg
8333%
Riboflavin (Vitamin B-2)
100 mg
7692%
Niacin (Vitamin B-3) (as Niacinamide)
100 mg
625%
Vitamin B-6 (from Pyridoxine HCl)
100 mg
5882%
Folate
680 mcg DFE(400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4167%
Biotin
100 mcg
333%
Pantothenic Acid (from Calcium Pantothenate)
100 mg
2000%
Choline (from Choline Bitartrate)
35 mg
6%
Inositol
100 mg
†
PABA (Para-Aminobenzoic Acid)
10 mg
†
The product is found useful for the following medical conditions
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Sustained relief
Most Useful Review
2 people found this helpful
Very effective; I truly experience sustainability. I’ve noticed this every time I use the toilet. I seem to sustain for about two days. When I have symptoms like throat pain, this treatment, along with fat-soluble vitamin C, works well to cure it.
Updated: Apr 2025
Depression details
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
Our investigation looked into how Vitamin B affects behavior and neurotransmitter levels in rats undergoing stress-induced depression.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
9
Struggles with depression
Most Useful Review
1 people found this helpful
The battle against chronic and seasonal depression can be overwhelming, especially when faced with these yellow supplements.
Updated: Apr 2025
Leg Cramps details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
9
Reduced leg cramps
Most Useful Review
NOW B-100 is effective! Since taking this supplement, the burning sensation in my legs with exertion has disappeared. My energy levels have increased, and my mood has improved over a couple of weeks. It's a great value, and the scent, although present, is not overpowering. The tablets are large, but swallowing them with another tablet makes it easier. I am a repeat customer and firmly believe in the benefits of B-100 for better health.
Updated: Mar 2026
Pelvic Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.4
9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
9
Eases pelvic pain
Most Useful Review
5 people found this helpful
I take it in spring and autumn as my osteochondrosis flares up. It eases spasms in my spine and removes pain radiating to my sternum, which I initially mistook for heart pain. I combine it with magnesium glycinate for better results.
Updated: Mar 2026
Attention Deficit Hyperactivity Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Improved memory
Most Useful Review
After taking vitamins, I did not run like an electric broom, but my overall condition improved: my memory and attention became better, and I started absorbing information more effectively. This is particularly significant for knowledge workers and students.
Updated: Mar 2026
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.3
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
7.5
Nervous system support
Most Useful Review
5 people found this helpful
My eye twitching due to stress and job changes was constant. I decided to take choline and B vitamins to strengthen my nervous system. Although the dosage of choline wasn't daily, it helped somewhat. B vitamins are essential for regulating the nervous system, immune support, and more. The tablets are large, yellow with a riboflavin smell. I recommend buying.
Updated: Mar 2026
Back Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Good
Based on 6 Reviews
8.3
9
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
7.5
Back pain reduced
Most Useful Review
31 people found this helpful
After learning to crush this product and mix it with yogurt, I noticed dramatic results. The probiotics increased absorption and within 45 minutes, my back pain was halved. I’m a bit concerned about the silica in it, but I plan to stock up on this product.
Updated: Mar 2026
Hair Loss details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 7 Reviews
8.3
8
We examined a new strain derived from the human microbiome, Cicaria, to see how it helps with hair loss. Through testing on individuals with hair loss and comparing them to a control group with normal scalps, we found that Cicaria produced key compounds like adenosine and biotin. Notably, hair follicles treated with these elements displayed longer lengths and maintained healthier root diameters. Furthermore, these treatments appeared to support the phases of hair growth, slowing the transition to hair loss. Thus, Cicaria shows potential as a treatment for hair loss.
9
Excellent effect
Most Useful Review
1 people found this helpful
Great complex; it’s well-selected in terms of both the B vitamin group and the dosage. No side effects like scabies or rashes. I recommend it for hair loss and low stomach acidity (which affects protein absorption). The effect is excellent.
Updated: Apr 2025
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
Methylcobalamin protects against liver failure
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.
In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
7.5
Supports liver health
Most Useful Review
1 people found this helpful
Daily health is important for me as I have a tendency towards liver disease. I've purchased this for health care and found it useful and harmless.
Updated: Mar 2026
Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Positive skin changes
Most Useful Review
9 people found this helpful
I take Pugh E alongside C, A, B, Omega 3-6-9, and Zn. I feel well. My complexion has improved significantly; my skin is soft, with minimal rashes (although they took a while to heal). The skin is no longer oily (perhaps because it's winter?), but it isn't dry either. My nails are slightly stronger but still tend to peel (I've worn shellac for a long time). My hair has fallen out less. It's hard to determine which vitamin contributed most, likely all combined. Yes, I’m a fan of vitamins; I had a cold last month, sore throat, and persistent snot, yet since taking vitamins, I’ve caught nothing. Bright changes have occurred, prompting an acquaintance to remark, "Wow, you look prettier!" - while I don’t see that dramatic change, I do notice positive improvements.
Updated: Mar 2026
Flu details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.2
7.5
Stress relief
Most Useful Review
I consistently take 1 tablet daily, which alleviates stress and tension. After three months, I've noticed reduced volume in my lower abdomen, often referred to as the stress tummy. My mood has significantly improved with fewer fluctuations.
Updated: Apr 2025
Neuropathy details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.2
8
Vitamin B12 improves vision recovery
We explored the effects of vitamin B12 on a 33-year-old woman living with HIV, who faced severe vision loss due to optic neuritis, a rare outcome of vitamin B12 deficiency. Prior to this, she had battled significant peripheral neuropathy treated with vitamin B12 tablets. After starting vitamin B12 injections following her vision loss, she experienced gradual improvement and regained her sight. This case highlights the importance of recognizing vitamin B12 deficiency, particularly since its signs can easily go unnoticed.
7.5
Cost-effective aid
Most Useful Review
23 people found this helpful
Helps with neuropathy. I use this for my peripheral neuropathy and have tried several brands over the last few years; this one is the most cost-effective and effective I’ve found. If you’re after a reputable oral vitamin B source, I highly recommend this one.
Updated: Apr 2025
Acne details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
10
No acne
Most Useful Review
10 people found this helpful
Great effect on acne! I initially took this for my health, but it significantly improved my acne. After two weeks, my skin was clear. I believe those struggling with rough skin should certainly try it. I've tried other vitamins, but this one proved most effective. I hope it helps! 😆
Updated: Apr 2026
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 10 Reviews
8
7
We examined the potential benefits of carnitine and folic acid in reducing bone pain and fatigue in patients with beta-thalassemia minor. Over three months, 73 participants received either carnitine alone, a combination of carnitine and folic acid, or folic acid alone, while a control group went without supplementation.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
9
Reduced spinal pain
Most Useful Review
5 people found this helpful
I take it during spring and autumn when my osteochondrosis flares up. It alleviates spasms in my spine and relieves pain radiating to my sternum. I also take magnesium glycinate alongside it.
Updated: Apr 2025
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 24 Reviews
8
7
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
9
Increased energy
Most Useful Review
3 people found this helpful
I feel it working! After giving birth, I struggled with fatigue, but since taking this supplement, my energy levels have significantly improved. There’s a big difference on days I take it compared to when I don’t. I will definitely buy it again.
Updated: Mar 2026
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 18 Reviews
8
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
9
No more ulcers
Most Useful Review
9 people found this helpful
Mouth ulcers have completely healed. Regardless of how many hours I sleep, I feel energised and no longer suffer from ulcers. After taking this supplement, I wake up earlier and feel fantastic. If you tire easily, I highly recommend trying it!
Updated: Apr 2026
Rash details
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
9
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
9
Rashes reduced significantly
Most Useful Review
5 people found this helpful
This is my salvation! The tablets are oval, quite large, yellowish with red speckles. They have no distinct taste (like talc or chalk) but a slight aroma of B vitamins. I take them each morning; as stated, these capsules are slow-release. I noticed bright yellow urine indicating the release of riboflavin (vitamin B2) later in the day. This drug is indeed long-acting. Additionally, I had a lip jam issue, which any previous vitamin lacked effect. However, after just five days of this supplement, my ailment disappeared! The skin rashes from wearing a mask (13 hours a day for work) have noticeably decreased. This has become my go-to supplement, stored in the fridge without issue.
Updated: Mar 2026
Nausea details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.7
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.
Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
7.5
No nausea experienced
Most Useful Review
3 people found this helpful
Good composition. The tablets are large but easy to swallow, and the smell is normal. I do not experience any feelings of nausea. I hope for good results as I have not been taking them long.
Updated: Mar 2026
Data last updated:
