Solgar B-Complex

Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. doi:10.1186/s13256-025-05095-4

Pernicious anemia case in Uganda

We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.

Nervous system support

Most Useful Review

125 people found this helpful

I ordered children's B vitamins to strengthen my nervous system. This complex stabilises my emotional state, improves my mood, and provides extra energy. It’s from a reliable manufacturer. I take it in the morning; the capsules are small and easy to swallow, and while there is a smell, it does not bother me.

High Cholesterol details

Niacin reduces cholesterol and oxidative stress

Based on 10 Researches

Hamoud S, Kaplan M, Meilin E, Hassan A, Torgovicky R, et al. Niacin administration significantly reduces oxidative stress in patients with hypercholesterolemia and low levels of high-density lipoprotein cholesterol. Am J Med Sci. 2013;345:195. doi:10.1097/MAJ.0b013e3182548c28

We examined how niacin (vitamin B3) impacts cholesterol levels and oxidative stress in patients with low HDL cholesterol. In this study, 17 participants with high cholesterol received niacin treatment over 12 weeks, while 8 healthy individuals served as controls.

The results were promising. We discovered a significant boost in HDL cholesterol and a drop in triglycerides among the patients. More importantly, niacin also reduced markers of oxidative stress, suggesting its benefits extend beyond just cholesterol management. However, CRP levels remained unchanged.

Remarkable hair improvement

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100 people found this helpful

I had high cholesterol and my doctor advised me to take a complex of B vitamins. I chose this one, and I wish I had discovered it sooner! After three months, my nails became strong and smooth, and my hair thick and silky. Shampoos won’t help if you're lacking vitamins internally; I learned this through experience. My hair has never looked so perfect, and my cholesterol levels returned to normal. I'm incredibly pleased with the results!

Athlete’s Foot details

Significant improvement

2 people found this helpful

Excellent. My mother suffered from a vitamin B deficiency, which caused pain in her feet, especially upon waking and her hands tingling. Thankfully, she has improved greatly since taking it. God bless her!

Back Pain details

Vitamin B12 effectively reduces pain

Based on 14 Researches

Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.

We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.

Effective for pain

Most Useful Review

266 people found this helpful

They genuinely assist with back pain! My mother suffered from neuralgia and finally found relief with Solgar's B vitamins. Regular medications were ineffective. Since she began taking these vitamins daily, her pain has significantly reduced. If she misses a week, the pain returns. It's frustrating to read reviews from those without spine issues. My mother is grateful for these effective vitamins. Thank you, iHerb!

Cold Sores details

I took this product during autumn and spring, and remarkably, I didn’t get sick or catch any colds. I believe these vitamins helped prevent any cold sores.

Insomnia details

Ohta T, Ando K, Iwata T, Ozaki N, Kayukawa Y, et al. Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12). Sleep. 1991;14:414.

Vitamin B12 aids sleep disorders

We observed two adolescents struggling with severe sleep-wake schedule disorders respond positively to high doses of vitamin B12, specifically methylcobalamin. The 15-year-old girl with delayed sleep phase syndrome and the 17-year-old boy with hypernychthemeral syndrome showed immediate improvements after receiving 3,000 micrograms per day.

Notably, there was no evidence of vitamin B12 deficiency in either case, as their levels remained in the normal range. The girl's sleep duration reduced from 10 hours to 7 hours, while the onset of her sleep moved from 2 a.m. to midnight. The boy's sleep-wake cycle also adjusted slightly, indicating potential benefits of methylcobalamin for these disorders.

Insomnia relief

Most Useful Review

43 people found this helpful

An excellent vitamin complex for health that has helped me sleep better and calm my nervous system. During my weight loss journey, I reduced my food intake, which initially led to hair loss and poor skin. As I managed to lose some weight and focused on a balanced diet, I began taking B vitamins. After starting this complex, I noticed a significant improvement: the insomnia vanished (I now even desire more sleep, which is a plus, as I couldn't sleep at all for months). My irritability decreased, and I realised how tough it must have been for my family. Furthermore, I gained energy and became more attentive, with better memory.

Multiple Sclerosis details

Relieves stomach pain

This wonderful supplement has been part of my routine for over 45 years, as recommended by my physician to alleviate irritable bowel symptoms. It significantly relieved my stomach pain when taken daily. Solgar is a trusted company with a long-standing reputation, making them my first choice. I couldn’t manage without this supplement.

Common Cold details

Zinc reduces diarrhea, colds in infants

Likely Very Effective

McDonald CM, Manji KP, Kisenge R, Aboud S, Spiegelman D, et al. Daily Zinc but Not Multivitamin Supplementation Reduces Diarrhea and Upper Respiratory Infections in Tanzanian Infants: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr. 2015;145:2153. doi:10.3945/jn.115.212308

We investigated the impact of daily multivitamin and zinc supplementation on the health of Tanzanian infants. In our randomized, double-blind study involving 2,400 infants, we compared the effects of these supplements against a placebo over 18 months.

Our findings revealed that while zinc significantly reduced occurrences of diarrhea and acute respiratory infections, multivitamins did not provide additional benefits. Ultimately, zinc supplementation starting at 6 weeks may be beneficial for reducing some common illnesses in infants, but multivitamins did not show any significant positive impact.

Effective for eyes

Most Useful Review

6 people found this helpful

I take Solgar B-Complex 50, one capsule daily. After 1.5 months, I observed significant improvement in my eye fatigue after long hours in front of screens. It worked far better than lutein and blueberries for my eyes. My nervous system felt stable, though I may need magnesium for optimal calm. I also experienced noticeable fat loss in my waist, while maintaining my skin condition and atopic dermatitis remained controlled with no exacerbations.

Eczema details

Improved skin condition

2 people found this helpful

Good, I liked the complex! It assisted in my battle against eczema. My skin has shown improvement.

Knee Pain details

Niacin intake eases knee osteoarthritis pain

Based on 2 Researches

Zheng Z, Luo H, Xue Q. Association between niacin intake and knee osteoarthritis pain and function: a longitudinal cohort study. Clin Rheumatol. 2024;43:753. doi:10.1007/s10067-023-06860-w

We investigated how niacin intake impacts pain and function in individuals with knee osteoarthritis (OA).

Using data from the Osteoarthritis Initiative, we analyzed niacin consumption alongside pain and functional scores.

Our findings reveal a significant association between higher niacin intake and reduced knee pain, suggesting that boosting niacin levels might improve the quality of life for OA patients.

Notably, specific groups, including middle-aged individuals and women, experienced even greater benefits.

Pain alleviation

Most Useful Review

1 people found this helpful

B vitamins are essential for energy. This complex has completely alleviated my knee pain and numbness, enhancing my mobility significantly since I started taking it. I wish to continue this for more energy in life.

Leg Cramps details

Vitamin B complex effective for cramps

Based on 2 Researches

Chan P, Huang TY, Chen YJ, Huang WP, Liu YC. Randomized, double-blind, placebo-controlled study of the safety and efficacy of vitamin B complex in the treatment of nocturnal leg cramps in elderly patients with hypertension. J Clin Pharmacol. 1998;38:1151.

We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.

The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.

Leg cramps alleviated

Most Useful Review

1 people found this helpful

Since starting this B vitamin complex, I’ve noticed a significant increase in my energy levels. My leg cramps have disappeared, and my back pain and stiff shoulders have resolved. I feel more capable in my daily life and plan to continue taking these vitamins.

Liver Disease details

Methylcobalamin protects against liver failure

Based on 4 Researches

Xu W, Wang Y, Cui S, Zheng Q, Lin Y, et al. Methylcobalamin protects against liver failure via engaging gasdermin E. Nat Commun. 2025;16:1233. doi:10.1038/s41467-024-54826-6

We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.

In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.

Relieved back pain

Most Useful Review

Thanks to this vitamin, I alleviated my back pain and improved liver function. I find it beneficial to supplement this vitamin several times a week.

Migraine details

Vitamin B2 significantly reduces migraines

Based on 15 Researches

Chen YS, Lee HF, Tsai CH, Hsu YY, Fang CJ, et al. Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis. Nutr Neurosci. 2022;25:1801. doi:10.1080/1028415X.2021.1904542

In our review and meta-analysis, we sought to understand how Vitamin B2 supplementation influences migraines. By examining nine studies with over 670 participants, we found that taking 400 mg of Vitamin B2 daily for three months significantly reduced the frequency, duration, and pain intensity of migraine attacks.

Our analysis revealed that Vitamin B2 wasn't just a minor help; it truly made a difference in managing migraine symptoms. This suggests a potential alternative to traditional pharmaceuticals, offering hope for migraine sufferers looking for effective prevention options.

Migraine improvement

Most Useful Review

4 people found this helpful

I read Fujikawa-sensei's blog and discovered B50 in the ATP set, so I decided to try it. I believe the quality is excellent, and the size is easy to consume. After just two months, my migraines, which I've had for over 20 years, have remarkably improved with the magnesium and ATP set.

We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.

7.5

Promotes recovery

Most Useful Review

4 people found this helpful

I must keep a bottle of B-complex at home. When I have a mouth ulcer, I take it for a few days and it aids my recovery. Believe me. If this comment is helpful to you, please click like. Thanks.

Anemia details

Di Sario F, Piloni F, Gasparini F, Serpetti E, Bruschi B, et al. Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy. Ital J Pediatr. 2024;50:186. doi:10.1186/s13052-024-01759-x

Based on 11 Researches

Case study: Vitamin B12 efficacy

We explored the case of a 23-month-old boy diagnosed with Imerslund-Gräsbeck syndrome (IGS), a rare disorder causing severe anemia. This child showed significant blood cell reduction and poor growth, which led to investigations identifying two genetic variants linked to his condition.

Remarkably, vitamin B12 replacement therapy resulted in a strong recovery. This case highlights how vital it is to diagnose IGS early in cases of severe anemia, ensuring timely treatment to avoid long-term complications, including potential neurological damage.

Improved overall health

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1 people found this helpful

I combined this medication with the iron from this brand. My mood swings have ceased, my skin condition has improved, and I feel significantly better. My hemoglobin rose from 90 to 130, which no pharmaceutical product had managed before. I have been suffering from anemia for over 10 years.

Chest Pain details

Vitamin B complex's minor impact on health

Martí-Carvajal AJ, Solà I, Lathyris D, Dayer M. Homocysteine-lowering interventions for preventing cardiovascular events. Cochrane Database Syst Rev. 2017;8:CD006612. doi:10.1002/14651858.CD006612.pub5

We evaluated the effects of vitamin B complex supplements on chest pain and heart health by reviewing 15 studies involving over 71,000 participants.

Our investigation revealed that while there were no significant differences in rates of heart attacks, overall deaths, or serious side effects between those receiving vitamin B complex and placebo, there was a slight reduction in stroke incidence.

However, the benefits were minimal and outcomes varied with dosages, indicating that more research is needed to draw firm conclusions about the effectiveness of these vitamin interventions on cardiovascular events.

Effective for pain

Most Useful Review

1 people found this helpful

I was experiencing pain in my knee and shoulder. I used it alongside glucosamine, and it was effective. The doctor prescribed it to help preserve my ear nerve, and I felt energised while taking it.

Dizziness details

Gabapentin and B vitamins reduce dizziness

Based on 7 Researches

Mimenza Alvarado A, Aguilar Navarro S. Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy. J Diabetes Res. 2016;2016:4078695. doi:10.1155/2016/4078695

We evaluated the effects of gabapentin combined with B vitamins (B1 and B12) against pregabalin for painful diabetic neuropathy. In this multicenter, randomized, and blind study, 270 patients participated over 12 weeks.

Both treatments reduced pain without a significant statistical difference. However, our findings indicated that the gabapentin plus B vitamin group experienced fewer cases of dizziness, highlighting a potential advantage in managing side effects compared to pregabalin. This could lead to a more comfortable treatment experience for patients.

Dizziness resolved

Most Useful Review

1 people found this helpful

Excellent! This is a great complex with good digestibility. To manage my mother's lifelong anaemia, she would drink a course of B vitamins. She often experienced substantial blood loss due to uterine fibroids, leading to haemoglobin levels below 70, along with light-headedness and drowsiness. Following the vitamin course, her dizziness disappeared, and her haemoglobin rose to 100. Another pleasant bonus is that her hair no longer falls out due to anaemia. I wholeheartedly recommend this product. I hope this review helps!

Frozen Shoulder details

1 people found this helpful

Since I began taking the B complex, my stiff shoulders, back pain, and leg numbness have all completely vanished, and I’ve noticed an improvement in my walking speed. These vitamins are crucial for energy production and support my overall vitality. I intend to continue consuming them for the energy I need to live.

Hair Loss details

Cicaria shows promise against hair loss

Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136

We examined a new strain derived from the human microbiome, Cicaria, to see how it helps with hair loss. Through testing on individuals with hair loss and comparing them to a control group with normal scalps, we found that Cicaria produced key compounds like adenosine and biotin. Notably, hair follicles treated with these elements displayed longer lengths and maintained healthier root diameters. Furthermore, these treatments appeared to support the phases of hair growth, slowing the transition to hair loss. Thus, Cicaria shows potential as a treatment for hair loss.

Incredible results

Most Useful Review

1 people found this helpful

I took this B complex after the end of breastfeeding when my hair started falling out rapidly. The quality is exceptional, and the results are incredible; hair loss stopped just weeks after beginning this complex. The B vitamins also positively impact the nervous system. I will order again; I highly recommend it.

Pelvic Pain details

Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrhoea. Indian J Med Res. 1996;103:227.

Based on 4 Researches

Vitamin B1 shows promising results

We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.

Decreased pelvic pain

Most Useful Review

The doses of vitamins are substantial, but it's challenging to overdoses on B vitamins, and not all are absorbed fully, so there's no need for concern. The packaging was well-sealed, and the capsules are of medium size and easy to swallow. I took one capsule daily after breakfast for a month. As for the results, the pain in my hip joint and lower back has decreased significantly, headaches have almost vanished, and I've become more relaxed. My sleep improved, and I no longer feel perpetually fatigued. Initially, I bought these capsules for health, but I've also noticed my nails are stronger and growing quickly, while my hair is still thin and brittle but growing faster. My skin has also improved, with small blemishes disappearing and becoming smoother, and I've experienced no side effects. I trust the quality of this brand.

Gastritis details

Improved stomach function

I ordered it on the advice of a gastroenterologist due to my gastritis, as B vitamins enhance stomach function. I also had tests for vitamins, and these vitamins are effective—I have tested them myself!

Cold details

Great! Excellent vitamins from the manufacturer. I no longer suffer from seasonal colds.

Menopause details

Cho KA, Kim YH, Woo SY, Ryu KH. Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle. Tissue Eng Regen Med. 2025. doi:10.1007/s13770-025-00709-w

Based on 8 Researches

Investigating T-MSCs for menopause

We investigated if small extracellular vesicles (sEVs) derived from tonsil stem cells could improve myo-inositol production, which is often disrupted by inflammation in menopausal women.

Over two weeks, mice received treatments mimicking this condition. Our results indicated that those receiving sEVs showed a restoration of myo-inositol levels and healthier muscle profiles compared to those that did not.

This research suggests that sEVs could be a promising option to improve metabolic health during menopause.

Helpful for menopause

Most Useful Review

My favourite vitamins, Solgar. I’ve been taking these for a long time; they are incredibly useful. They help me cope with menopause. I always choose only these!

Sleep Apnea details

3 people found this helpful

Taking the B-Complex dietary supplement boosted my mood and suppressed anxiety, which was my main aim. It’s safe, hypoallergenic, and seemed to improve my complexion and sleep. The results were impressive, and I would recommend it for better sleep and overall wellbeing.

Depression details

Vitamin B may alleviate depression symptoms

Based on 12 Researches

USERS' SCORE

Good

Based on 16 Reviews

Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. doi:10.12182/20250160608

Our investigation looked into how Vitamin B affects behavior and neurotransmitter levels in rats undergoing stress-induced depression.

We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.

The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.

Reduced insomnia

Most Useful Review

31 people found this helpful

This is the best B vitamin complex. It saved me from insomnia and mild depression, providing energy, focus, and improved mood. The can is large enough for two courses, making it economical. However, it's unfortunate that they are no longer available for order to Russia.

Urinary Tract Infection details

Cracks healed quickly

10 people found this helpful

For health reasons, I frequently take B vitamins. After surgeries on my digestive tract, I struggled with cracks in the corners of my mouth and insomnia. The cracks persisted for months until I discovered a lack of B2 (riboflavin). Once I started this complex of B vitamins, the cracks began to heal within a week, and I started sleeping well again. I’ve since forgotten those problems, which now seem like a bad dream!

Chronic Cough details

This excellent vitamin complex has really returned my energy. There's no need for a higher dosage. The effect becomes noticeable about a week after starting, with much more energy and improved mood. My chronic fatigue has disappeared.

Rash details

Adie MA, Martes Gomez M, Yom J, Durand M, Wertheimer F, et al. Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition. J Investig Med High Impact Case Rep. 2023;11:23247096231168111. doi:10.1177/23247096231168111

Likely Very Effective

Based on 2 Researches

Vitamin B deficiency leads to rash

We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.

Waking up energized

Most Useful Review

1 people found this helpful

These magical B vitamins are incredible for stress, depression, fatigue, drowsiness, and the autumn blues. Over time, I felt revitalised; my mood improved, and I gained strength and energy, awakening to life again. They significantly benefit the nervous system, alleviating trivial anxieties and gloom. However, I did experience a side effect: during one course, I developed rashes on my face, possibly due to a vitamin overdose.

Chronic Fatigue Syndrome details

B12 and folic acid show variability

Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648

We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.

Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.

However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.

Enhanced energy levels

Most Useful Review

1 people found this helpful

I highly recommend Solgar B-Complex "50". It's been a fantastic addition to my daily routine. I noticed an increase in energy levels and improved mental clarity, which helped with my chronic fatigue syndrome symptoms. The capsules are gentle on my stomach, and I felt calmer in stressful situations. It's a quality supplement that offers comprehensive B vitamins.

Allergies details

Pinitol may reduce allergy symptoms

You X, Sun X, Kong J, Tian J, Shi Y, et al. D-Pinitol Attenuated Ovalbumin-induced Allergic Rhinitis in Experimental Mice via Balancing Th1/Th2 Response. Iran J Allergy Asthma Immunol. 2021;20:672. doi:10.18502/ijaai.v20i6.8017

We evaluated how D-Pinitol affects allergic rhinitis (AR) in a controlled study using mice.

By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.

Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.

No side effects

Most Useful Review

3 people found this helpful

Good result. My husband and I take these capsules every morning. Like all B vitamin preparations, this complex acts quickly, literally after the first intake. Neither of us experienced side effects or allergies. I feel my nerves are stable, and I no longer twitch over trivial matters, which is wonderful.

Bloating details

Great product! I love it, and so does my family. I never thought I would find a one-stop shop for all my needs, but iHerb is superb! The fast shipment was impressive. Since starting this, my digestion has improved significantly, with no bloating or constipation. The packaging is excellent, and the product quality is fantastic. The taste is also great!

Headache details

Pediatric migraine treatment with riboflavin

Based on 15 Researches

Das R, Qubty W. Retrospective Observational Study on Riboflavin Prophylaxis in Child and Adolescent Migraine. Pediatr Neurol. 2021;114:5. doi:10.1016/j.pediatrneurol.2020.09.009

Our examination focused on the effectiveness of riboflavin, a form of Vitamin B2, in treating migraines in children and adolescents aged six to 18. We conducted a retrospective observational study involving 42 patients, where we measured the frequency, intensity, and duration of their headaches.

Remarkably, we found significant reductions in headache days per month, with intensity and duration also decreasing. Most importantly, riboflavin helped decrease the reliance on acute medication and fewer missed school days. We suggest this affordable treatment as a safe option for pediatric migraines.

Headaches almost gone

Most Useful Review

6 people found this helpful

I purchased these capsules for health rather than beauty, yet I've seen remarkable effects! My nails have become denser and are growing rapidly. My headaches have almost disappeared, and I've felt much calmer, no longer reacting overly to minor annoyances. While B vitamins won’t turn you into a 'vegetable', I’ve found that my sleep quality has improved, and I no longer feel perpetually fatigued. Overall, I'm very satisfied and would definitely recommend them.

Nausea details

Cariban effectively relieves pregnancy nausea

Based on 4 Researches

Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. doi:10.1007/s40268-023-00425-7

We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.

Ideal vitamin choice

Most Useful Review

1 people found this helpful

This vitamin has everything needed without causing nausea, unlike previous strong B vitamins. Highly recommend it!

Heartburn details

1 people found this helpful

Recommend. Proven with clear results. I was very pleased, as previous dietary supplements regularly caused discomfort and heartburn. Tests confirm that this drug works effectively.

Cardiovascular Disease details

Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413

Vitamin B6 aids heart recovery

We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.

Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.

Improved mood

Most Useful Review

7 people found this helpful

I took this for my 78-year-old mother on her doctor's advice for cardiovascular disease. We were amazed at the results! She overcame autumn depression and fatigue, regained her energy, and now walks for two hours daily, feeling cheerful and free from joint pain. Solgar is impressive!

Kidney Stones details

Problem resolution achieved

These vitamins effectively resolved my long-standing issue with barley in my eyes, which had required surgery. The optometrist advised me to take these, and it turned out I avoided the need for an operation! However, I noticed that taking them at night was difficult on my kidneys.

Food Poisoning details

2 people found this helpful

The complex is not suitable for everyone and may cause food poisoning. Although I love Solgar vitamins, I cannot tolerate complex B vitamins. They increased my irritability, and my doctor advised taking B1, B6, B2, and B12 separately due to their incompatibility. The high dosage of 50 mg of B9 is excessive for me. This combination caused negative reactions, resulting in the vitamins being left untouched on the shelf, causing a foul smell. The endocrinologist warned that such combinations can lead to poisoning.

Acne details