NOW Supplements Probiotic-10

Bifidobacterium lactis reduced diarrhea duration

Based on 95 Researches

Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Eur J Clin Nutr. 2024;78:501. doi:10.1038/s41430-024-01428-6

We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.

No more diarrhea

Most Useful Review

From a small dose of 5 billion to 25 billion, I am now taking 100 billion per day. I feel excellent, with no more issues of diarrhea or constipation in my daily life. I used to constantly need to find a restroom. I highly recommend this supplement for its numerous benefits to overall health.

Pelvic Pain details

Lactobacillus association with pelvic pain

Questionable

Based on 2 Researches

Abernethy MG, Rosenfeld A, White JR, Mueller MG, Lewicky-Gaupp C, et al. Urinary Microbiome and Cytokine Levels in Women With Interstitial Cystitis. Obstet Gynecol. 2017;129:500. doi:10.1097/AOG.0000000000001892

We examined the urinary microbiome of women with interstitial cystitis and found it less diverse and containing fewer Lactobacillus acidophilus compared to a control group.

This lack of Lactobacillus was linked to more severe symptoms and poor quality of life. While we noted some associations between higher inflammatory markers and the severity of symptoms, we didn’t see a clear causal relationship.

Essentially, we’re still unsure if the presence of Lactobacillus can effectively reduce pelvic pain in this context.

9.5

Quick relief

Most Useful Review

A renowned company whose products are excellent. Those suffering from digestive or colon issues should not hesitate to take this medicine and will feel better from the first use. God willing, it will alleviate most stomach and colon problems, including the intense pain and reflux associated with them.

We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.

Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.

Most important supplement

Most Useful Review

It is the most crucial supplement one can take for both eczema and overall health.

Flu details

Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009;124:e172. doi:10.1542/peds.2008-2666

Likely Very Effective

Probiotics reduce flu symptoms

We examined how Lactobacillus acidophilus could help reduce cold and flu-like symptoms in young children during the winter months. In this well-structured study, 326 children aged 3 to 5 participated. They were randomly assigned to one of three groups: one received a placebo, while the others were given either Lactobacillus acidophilus alone or in combination with another probiotic, Bifidobacterium animalis subsp lactis.

Over a period of six months, the children in both probiotic groups reported significantly fewer symptoms and shorter durations of ailments compared to those on the placebo. For instance, the incidence of fever dropped by 53% to 73%, while coughing and rhinorrhea (a runny nose) also saw impressive reductions. Children taking probiotics needed antibiotics much less often and missed fewer days of childcare due to illness.

Overall, this study suggests that incorporating daily Lactobacillus acidophilus into children's diets can be an effective approach to bolster their health during flu season. It shows promise as a safe and helpful way to reduce common winter illnesses in young kids.

9.5

No colds or flus

Most Useful Review

No more sickness! Although they did not arrive cold or refrigerated, these have significantly boosted my health and immune system. My stomach health has improved, and I haven’t caught any colds or flus since starting these. I feel much stronger and have peace of mind when in public around sick individuals.

Food Poisoning details

Lacticaseibacillus rhamnosus shows promise

Based on 7 Researches

Kathayat D, Closs G, Helmy YA, Deblais L, Srivastava V, et al. In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides. Probiotics Antimicrob Proteins. 2022;14:1012. doi:10.1007/s12602-021-09840-1

We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.

Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.

9.5

Stomach issue resolution

Most Useful Review

This is by far the best probiotic I've ever taken. I've never noticed benefits from probiotics before, but this product completely resolved my stomach issues that had persisted for months. My anxiety has also lessened, likely due to this remedy. Digestion has vastly improved, and I’ve not experienced bloating since. Though pricey, I recommend it for anyone with stomach or gut troubles.

Leg Cramps details

Significant improvement

Most Useful Review

The first time I tried these capsules, I suffered from a nervous colon, leg cramps, gas, diarrhoea, constipation, colic, bloating, and slow digestion. However, I've noticed considerable improvement since using them. I take them with breakfast for the best results and avoid taking them late in the evening. I intend to buy more as I have found them beneficial.

Irritable Bowel Syndrome details

Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. doi:10.1080/19490976.2024.2338322

Based on 76 Researches

CECT 7347 reduces IBS-D symptoms

A randomized, double-blind, placebo-controlled trial exploring CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) revealed promising results for diarrhea-predominant irritable bowel syndrome (IBS-D).

We found that after 12 weeks, both ES1 and HT-ES1 significantly reduced symptom severity compared to a placebo, as shown by lower IBS-Symptom Severity Scale scores.

Other improvements included better stool consistency and quality of life. This study marks a breakthrough with the first positive findings for a probiotic or postbiotic from this strain specifically for IBS-D patients.

9.5

Improved condition quickly

Most Useful Review

After developing irritable bowel syndrome from stress in the military, I had severe abdominal pain and diarrhoea. I tried Now Foods lactobacillus, taking two 100 billion tablets daily. Remarkably, my symptoms improved significantly within days. This product has become part of my daily routine.

Bloating details

Bifidobacterium lactis alleviates bloating

Based on 54 Researches

Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. doi:10.1111/j.1365-2036.2008.03853.x

We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.

9.5

Gut issues resolved

Most Useful Review

This is by far the best probiotic I've taken. Unlike previous probiotics, this one has effectively cleared up my stomach issues and significantly reduced my bloating. I also noticed an improvement in my skin, which looks brighter. Although it’s a bit pricey, it's worth it if you have gut problems.

Chronic Cough details

I ordered this probiotic when I had a chronic cough that persisted despite trying various remedies (I'm usually reluctant to take antibiotics). It worked excellently.

Allergies details

Lactobacillus salivarius lowers allergy symptoms

Based on 86 Researches

Lin TY, Chen CJ, Chen LK, Wen SH, Jan RH. Effect of probiotics on allergic rhinitis in Df, Dp or dust-sensitive children: a randomized double blind controlled trial. Indian Pediatr. 2013;50:209.

We explored the impact of Lactobacillus salivarius on allergic rhinitis symptoms in children through a double-blind, randomized controlled trial. Over 12 weeks, children either received the probiotic or a placebo.

Results showed a decrease in rhinitis symptoms and medication usage in those treated with the probiotic. However, there were no significant changes in immunological or blood cell measures when comparing the two groups.

Overall, Lactobacillus salivarius may be beneficial for reducing symptoms of allergic rhinitis in children.

9.5

Less allergic symptoms

Most Useful Review

Since I began taking probiotics regularly, my bowel movements have stabilised, and the frequency of diarrhoea has significantly decreased. Additionally, I experienced less frequent runny nose and itchy eyes due to allergies, especially in the mornings when the eye itching has almost vanished. Knowing that it supports my health has been a great benefit.

Autoimmune Disorder details

Liao W, Zhang X, Jia C, Chen W, Cai Y, et al. LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway. Food Funct. 2025;16:475. doi:10.1039/d4fo03966a

Based on 44 Researches

LC-STH-13 counters lupus effects

We explored the effects of probiotic LC-STH-13 on systemic lupus erythematosus (SLE) in MRL/lpr mice. Our study demonstrated that LC-STH-13 significantly decreased harmful autoantibodies and rebalanced specific immune cells.

We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.

9.5

Gut health improvement

Most Useful Review

One of the best probiotics around, made from high-quality ingredients with an excellent selection of strains. After ordering about 10 times, it's my favourite supplement and my choice for family members too. I felt an immediate difference in my gut; constipation disappeared, nutrition absorption improved, and bloating was reduced, aiding digestion.

Urinary Tract Infection details

Probiotics effective for UTI prevention

Based on 29 Researches

Sadeghi-Bojd S, Naghshizadian R, Mazaheri M, Ghane Sharbaf F, Assadi F. Efficacy of Probiotic Prophylaxis After The First Febrile Urinary Tract Infection in Children With Normal Urinary Tracts. J Pediatric Infect Dis Soc. 2020;9:305. doi:10.1093/jpids/piz025

We investigated whether a probiotic mix containing Lactobacillus acidophilus could prevent recurrent urinary tract infections (UTIs) in children aged 4 months to 5 years.

The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.

Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.

9.5

Yeast infection relief

Most Useful Review

This might be a bit sensitive to discuss, but many women, including myself, have experienced girly issues like certain infections. I don't understand why, as I maintain good hygiene. I previously relied on yoghurts, but they took ages to work. Instead, I've switched to probiotic pills to better fight yeast infections, and they’ve worked wonders for me. Within a week, my yeast infection seemed to clear up completely. Since starting these, I haven't faced that issue again. I even noticed that the eczema around my lips has been less irritated. I can't say if that's intentional, but I’m pleased with the results. I would surely repurchase this!

High Cholesterol details

Probiotic strain reduces cholesterol

Based on 16 Researches

Park S, Kang J, Choi S, Park H, Hwang E, et al. Cholesterol-lowering effect of Lactobacillus rhamnosus BFE5264 and its influence on the gut microbiome and propionate level in a murine model. PLoS One. 2018;13:e0203150. doi:10.1371/journal.pone.0203150

We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.

Improves gut health

Most Useful Review

I loved this supplement and will undoubtedly buy it again. I noticed an improvement in my gut health and digestion—these strains are excellent for the microbiome. It has no taste, and the package size of 30 pills is convenient. Great quality. Highly recommended for anyone wanting to enhance their gut health.

Constipation details