Lacticaseibacillus rhamnosus shows promiseIn Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
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