'
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
MethylSulfonylMethane (MSM)
1,000 mg

The product is found useful for the following medical conditions

Arthritis

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 55 Reviews
8.8
8
MSM improves mild knee pain
Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.
Most Relevant Research
In a well-structured randomized, double-blind, placebo-controlled trial, we explored how methylsulfonylmethane (MSM) affects those experiencing mild knee pain. The study involved 88 healthy Japanese participants, split evenly into two groups where one received 200 mg of MSM while the other received a placebo for 12 weeks.

By measuring the total score on the Japanese Knee Osteoarthritis Measure (JKOM) at the end of the trial, we found that the MSM group showed a significant improvement compared to the placebo group. Specifically, total JKOM scores changed markedly, with an improvement in knee and systemic health reported by participants who took MSM.

Our findings suggest that MSM might be beneficial for individuals with mild knee pain, marking it as a useful supplement for enhancing joint health. The positive outcomes underscore the potential of MSM as a supportive treatment option for managing mild arthritic conditions.
9
Significant pain relief
Most Useful Review
I suffer from an undiagnosed condition producing daily musculoskeletal pain. After discovering that higher doses of MSM could provide relief, I began taking up to 16 capsules daily spaced out, which resulted in fantastic pain relief. Research suggests MSM is effective for knee arthritis. Now, I assess my pain level and adjust my MSM intake accordingly. This supplement is benign and very helpful, and I highly recommend it.

Back Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 94 Reviews
8.8
9.5
Decreased pain level
Most Useful Review
As a retired black belt, I suffered from chronic back and leg pain due to scoliosis. I began using MSM Sulfur and was amazed at its efficacy. It has significantly increased my range of motion and decreased 10 years of persistent pain. I feel more active and confident now, even enjoying physical exercise again.

Bone Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.8
9.5
Stronger bones overall
Most Useful Review
This MSM powder is a must for cellular, tissue, and bone healing. I've used it for decades post-knee injury, and after two years of minimal daily intake, my spurs and pain have vanished. At over 60 years old, I feel fantastic and believe in this product’s effectiveness for overall health and toxin elimination.

Allergies

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 20 Reviews
8.6
9.5
Asthma eliminated
Most Useful Review
This product is a must-have! My husband and I have experienced incredible benefits from MSM—his joint pain has diminished, my severe PMS pain is gone, and I no longer suffer from allergies and asthma. I've stopped using my inhaler completely! Both of us enjoy exercising without the hindrance of allergy-related issues.

Asthma

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
USERS' SCORE
Good
Based on 1 Review
8.6
8
Asthma medication boosts lung function
An application of model-fitting procedures for marginal structural models.
Most Relevant Research
We explored the effectiveness of asthma rescue medication on lung function through a thorough analysis of data collected during the Fresno Asthmatic Children's Environment Study from 2000 to 2002. Our research utilized a method known as inverse probability of treatment weighting (IPTW) to evaluate treatment effects in an observational study context. This approach helps us account for various confounding factors that might influence the outcomes we observe.

In our findings, traditional regression methods suggested that there was no significant association between medication use and improved lung function. This might seem surprising, as one would intuitively expect that asthma medication helps improve breathing. However, we believed that this outcome was likely influenced by confounders, such as asthma symptoms and severity, which can muddle the clear effects of medication.

When we applied our marginal structural model approach, we discovered a causal link between medication use and a 7% improvement in pulmonary function. This suggests that when we accounted for other influences adequately, asthma rescue medication does indeed have a positive impact, contrary to previous findings.

We hope that our discussion on the importance of proper model selection and fitting procedures encourages more researchers to consider these aspects seriously when evaluating treatment effects. By understanding the subtleties of our methodologies, we can better justify our conclusions in the realm of asthma treatment.
10
Asthma resolved
Most Useful Review
Where to start? My husband was advised to take DMSO for joint pain, and while it worked, it caused bad breath. After researching, we began MSM. We've taken it for about two months; it alleviated his joint pain and gut issues, and my severe PMS pain is non-existent. Most significantly, my asthma has disappeared, allowing me to enjoy exercise again without an inhaler!

Bloating

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Miracle drug
Most Useful Review
Where to begin? After my husband used DMSO for his painful joints, we switched to MSM. It has nearly eradicated his joint pain, regulated his gut, and eliminated his IBS. I've also seen tremendous benefits: no more severe PMS pain, my belly bloating is gone, and I have normal energy levels. Even my asthma is gone! This supplement is fantastic, and my skin has cleared up too!

Bronchitis

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Fights bronchitis effectively
Most Useful Review
An excellent antioxidant. I purchased this to combat my bronchitis, and it truly made a difference! Plus, it offers numerous other benefits (just google!)... highly recommended.

Chemotherapy

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Stimulated hair growth
Most Useful Review
MSM has been a Godsend for me after back surgery and twin spinal cord implants. I have not lost any hair after chemotherapy, as it stimulates hair and nail growth while alleviating aching muscles from osteoporosis-arthritis. I take it twice daily, 1000mg, but don’t stop taking it when travelling, or the aches return.

Cold

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Stops cold sweats
Most Useful Review
I was experiencing terrible night sweats along with being hot and cold throughout the day and night. After just one day of taking this, everything stopped, which is hard to believe. I am going to continue using it. Pre-menopause is not enjoyable!

Cough

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Cough cleared effectively
Most Useful Review
Great stuff! I took it for inflammation in the lungs and it helped clear my lungs when I had a really bad cough! I take these pills daily for immune support, and they've proven to be truly beneficial.

Ear Infection

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Effective prevention
Most Useful Review
Works great! There’s no bitter taste with this product. My husband used to suffer from sinus infections every year, but after starting this product several years ago, he hasn't had an infection since!

Eczema

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
10
Eczema free
Most Useful Review
I have dealt with eczema since childhood, but after researching, I tried this product targeting sulfur absorption. Now, two months later, I am eczema free. Taking one capsule each morning has proven effective, and I'm relieved at the improvement in my skin condition.

Leg Cramps

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
10
Cramps alleviated
Most Useful Review
This fixed my muscle cramps in my legs, hands, and neck. I began developing severe cramps in my legs and hands that originated in my tendons and ligaments. After consulting several doctors and undergoing tests without answers, a friend recommended this, and I decided to try it. Since then, I haven't experienced any cramps. If I become dehydrated, this helps to hydrate my muscles and prevents tightness in my neck, alleviating headaches and TMJ flare-ups.

Menopause

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Night sweats stopped
Most Useful Review
I was having awful night sweats, feeling hot and cold throughout the day and night. When I purchased this, I had no idea why I made that choice, but I started taking it anyway! Within a day, everything stopped, and I still cannot believe it. I will definitely keep taking this. Pre-menopause is not enjoyable at all!

Neuropathy

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Total relief
Most Useful Review
MSM has been incredibly effective in alleviating the pain and itching in my legs and feet caused by neuropathy. I cannot go without it.

Pots

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Pain and inflammation relief
Most Useful Review
This is the first product I've found that immediately alleviated inflammation in my joints and reduced arthritis pain. I take two a day and also give one to my old dog for his joints, noticing a distinct improvement in his mobility. It also seems to aid in reducing age spots, clearing my rosacea, and alleviating other health issues. A miracle drug!

Reflux

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
No recurrence
Most Useful Review
This works for me. I use this product for acid reflux/GERD, and it works hands down. I have been using MSM for years without recurrence. I also have food allergies, and it has become essential in minimising flare-ups.

Rosacea

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Miracle drug
Most Useful Review
This product reduced inflammation in my joints and eased arthritis pain. More importantly, my rosacea has cleared up significantly along with fading age spots and stopping sinus issues. A truly remarkable remedy.

Hair Loss

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 1 Review
8.5
9
MSM shows promise for hair loss
EVALUATION OF THE EFFECT OF TOPICALLY APPLIED METHYLSULFONYLMETHANE AND THEIR COMBINATION WITH MINOXIDIL SOLUTION FOR IMPROVEMENT OF HAIR GROWTH IN MALE MICE.
Most Relevant Research
We explored the potential of Methylsulfonylmethane (MSM) as a treatment to minimize hair loss. In our study, we used twenty male Wister Albino mice, carefully dividing them into four groups to test different treatments: a control group with distilled water, a group treated with Minoxidil, one with MSM, and a group receiving a combination of MSM and Minoxidil.

Over the course of the study, we observed that the mice given MSM experienced notable improvements compared to the control group. Specifically, hair growth increased, and hair follicle numbers were significantly higher in the groups treated with MSM, whether alone or in combination with Minoxidil.

Additionally, we found a reduction in tissue levels of 8-isoprostane—a marker of oxidative stress—in the medicated groups, pointing to MSM’s antioxidant properties. There was also an increase in vascular endothelial growth factor, suggesting enhanced blood supply to the hair follicles.

Our overall conclusion is that MSM shows promise in reducing hair loss through its remarkable antioxidant and anti-inflammatory effects in male mice. This research indicates that MSM could be a valuable ally in the fight against hair loss.
8.8
Relieved joint pain
Most Useful Review
This supplement has significantly alleviated my joint pain from lupus and has made a remarkable difference in my hair loss. I truly love this product!

Hives

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8
Pain relief achieved
Most Useful Review
It works for me. I have no idea what other factors may be involved, but the pain in my hips and lower back (caused by hives) is gone. I was limping badly every time I stood and tried to walk, but that’s no longer an issue. Most days, I only take two capsules—one in the morning and one at bedtime. My only concern was that in the past, I had gotten hives from sulpha, but that was years ago and didn’t happen with this product. I’m a happy customer.

Hypothyroidism

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Aids various ailments
Most Useful Review
I adore this product. One of my favourite supplements discovered over the years! This Jarrow brand MSM dissolves well in water. I take it with Bulk Supplements brand L-Glutamine, which is good for skin, gut lining, and hair. With Hashimoto's hypothyroidism, this definitely alleviates some of my symptoms!

Rheumatoid Arthritis

SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
4
USERS' SCORE
Good
Based on 1 Review
8.5
4
MSM and BA show limited effects
The "MESACA" study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis.
Most Relevant Research
In our clinical trial, we investigated the effects of methylsulfonylmethane (MSM) combined with boswellic acids (BA) on individuals suffering from knee arthritis, a chronic condition often characterized by joint pain and inflammation. We enrolled 60 participants who were randomly divided into two groups: one group received the MSM and BA treatment for 60 days, and the other group was given a placebo.

Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.

However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.
8.8
Prevents flare-ups
Most Useful Review
Good for stiff joints! This product is excellent for rheumatoid arthritis and taken daily, it prevents flare-ups effectively.

Sinusitis

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9.5
USERS' SCORE
Good
Based on 1 Review
8.5
9.5
Maxillary sinus mucocele insights
Maxillary sinus mucocele: predisposing factors, clinical presentations, and treatment.
Most Relevant Research
We aimed to understand how maxillary sinus mucocele (MSM) influences sinusitis and what treatment options are most effective. Our study observed 36 patients diagnosed with MSM through computed tomography. We looked at their medical histories, symptoms, and surgical treatments, all while following them for at least three years after their procedures.

Our findings revealed that several factors could predispose individuals to MSM, such as chronic sinusitis, past surgeries, allergic rhinitis, and nasal injuries. Interestingly, for about 56% of the patients, we couldn’t identify a clear cause for their condition. The symptoms noted by patients included unilateral cheek pain, swelling, nasal blockages, and even proptosis, which all relate back to the pressure and expansion of the mucocele.

We found that the trans-nasal endoscopic approach for treating MSM, specifically through marsupialization, was both effective and safe. During treatment, patients with more extensive mucoceles required additional steps to ensure the instruments could be properly introduced. Fortunately, each patient reported a complete resolution of their symptoms, and none needed additional surgeries afterward.
8
Allergies improved significantly
Most Useful Review
This is essential! As someone who suffers from sulphur deficiency, these supplements have been a blessing. They've significantly reduced my allergic reactions, skin issues, and sinusitis. I've been taking them for over a year at a dose of 6000mg daily, and my family noticed major improvements in my health; they have started taking them and are experiencing even better results.

Sleep Apnea

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
9
Pain relief, better sleep
Most Useful Review
Must have, for probably everyone! My husband was advised to use DMSO for his painful joints which worked well but caused bad breath. After researching, we began taking MSM, 4000 to 6000 mg a day, and noticed numerous improvements in just two months. It has nearly eradicated my husband's joint pains and regulated his gut, eliminating IBS. He now sleeps much better, having previously suffered from sleep apnea. Personally, I no longer experience severe PMS pain, my gut is normalised, and I have more energy. Notably, asthma issues have vanished as well. We've also been free from sinus problems and allergies for months, and I'm relieved not to need my inhaler anymore.

Common Cold

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.4
7.5
Joint improvement
Most Useful Review
Very useful stuff for joints and more! I started taking MSM plus collagen and vitamin C, and the condition of my joints has significantly improved—no more pain, and I can now endure heavy loads. I used to catch a cold frequently from drafts, but since I've made this change, sitting in front of an open winter window in just my shorts didn’t faze me. I find the capsules convenient, as they save time compared to the MSM powder.

Bruise

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.4
7.5
Pain relief noted
Most Useful Review
Good. Helps with my knee pain and my joint issues. I've been using it for a week and have seen improvement, especially on my toe that I bruised, which had been painful for months.

Diabetes

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.4
7.5
Helps fatigue management
Most Useful Review
Helped my fibromyalgia fatigue, diabetes and chronic fatigue exhaustion. Friends advised me to buy this for my fatigue since they're pleased with it. I did and noticed a slight difference after a few days. After a week, there’s a definite improvement. It’s not a cure, but it noticeably aids my fatigue levels. I have chronic fatigue, fibromyalgia and diabetes, and this helps me manage the day. Worth buying and trying.

Skin Cancer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.2
4.8
No effect on skin cancer
Most Useful Review
I tried this product after an accident that left me limping. I no longer limp and my hand pain has vanished. However, it hasn't significantly impacted my skin cancer issues, which is why I rated it four stars instead of five.

Cancer

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
USERS' SCORE
Good
Based on 1 Review
8.1
7
MSM anal cancer treatment feasibility
Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia.
Most Relevant Research
We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population.

In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.

Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.

Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
3.8
No effect on cancer
Most Useful Review
Works. I started taking this due to a car accident that left me limping on a damaged knee. I no longer limp; I did not have knee surgery, and the pain in my hands has gone. Four stars instead of five is for the cancer aspect, as the product does not provide the percentage of organic sulphur in it. It has had no effect on my skin cancer problem.

Constipation

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8
9.5
Joint pain relief
Most Useful Review
Must have, for probably everyone! My husband was recommended DMSO for his painful joints, which worked but caused bad breath. After some research, we began taking MSM, around 4000 to 6000 mg daily. We have noticed numerous benefits in just two months; my husband's joint pains have almost vanished, and he no longer suffers from IBS or sleep issues. I've seen significant improvements too: my PMS pain is much reduced, and I’ve regulated my gut which had previously experienced constipation. I no longer have chronic fatigue, and respiratory issues like asthma are gone. My overall energy is normal, and I even sleep soundly now. This stuff is quite miraculous, and we've experienced fewer colds too.

Heartburn

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 1 Review
7.9
2.3
Heartburn caution
Most Useful Review
It felt like heartburn city for me. A crucial suggestion missing from the label is to take this after eating, along with two Pepcid Completes for every MSM capsule. Otherwise, you're in for a severe case of heartburn/acid reflux. After three weeks, it hasn't alleviated my pain, but everyone's different. Just please don't take it without food, and ensure you have Pepcid on hand to calm the heartburn.

Acne

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 32 Reviews
7.4
9.5
Reduces acne significantly
Most Useful Review
Helps reduce acne and constipation! I struggle with adult acne and read that MSM can assist. I decided to try this brand and have been very impressed. My breakouts have significantly decreased. A bonus is that it also helps with my constipation issues. Initially, I was hesitant as I feared it might cause gas, but thankfully, it doesn’t!

Headache

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.4
9
Erenumab reduces migraine medication use
Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials.
Most Relevant Research
We explored how erenumab impacts the use of acute headache medication, especially migraine-specific medications (MSM). The study analyzed data from two major clinical trials involving patients with episodic migraine (EM) and chronic migraine (CM). Participants received either erenumab or placebo over a set period, allowing us to compare medication usage accurately.

Our findings indicate that treatment with erenumab led to a significant decrease in the number of days patients used acute headache medications, particularly in those relying on MSM. This reduction was observed in both episodic and chronic migraine patients, suggesting that erenumab not only helps manage migraines but may also help mitigate the need for additional acute treatment.

Overall, these results highlight the potential benefits of erenumab in addressing not just the frequency of migraines but also reducing dependence on medications traditionally used for acute migraine relief.
9.5
Headache relief
Most Useful Review
Fibromyalgia has vanished! This MSM is high quality and absorbs quickly. My husband's asthma and plantar fasciitis improved. However, I recommend starting with one or two capsules a day with a meal, as it can detox your body, causing headaches if increased too quickly. Keep L. Arginine and L. Ornithine on hand for detox symptoms. My skin looks fabulous, aches are gone, and my immune system has improved. I truly believe in the miracle of MSM!
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