Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Magnesium(from 513 mg Buffered Magnesium Glycinate Chelate Complex [Magnesium Oxide and Magnesium Bisglycinate])
200 mg
48%
Magnesium-Rich Plants BlendOrganic Spinach LeafOrganic Chard LeafOrganic Okra FruitOrganic Quinoa Grain (Chenopodium quinoa)Organic Black Bean (Phaseolus vulgaris)Organic Pumpkin SeedOrganic Sunflower SeedOrganic Flaxseed
30 mg
**
The product is found useful for the following medical conditions
Osteoporosis details
SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.2
USERS' SCORE
Good
Based on 5 Reviews
8.6
9
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
9
Bone health benefits
Most Useful Review
89 people found this helpful
Magnesium is crucial for everyone! Most people lack it. This brand, derived from a food source, excels in benefits ranging from bone health and formation to absorbing calcium and preventing osteoporosis. Consistent intake is necessary!
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
Magnesium oxide shows promise against EHEC
We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.
9
No side effects
Most Useful Review
5 people found this helpful
The most beloved magnesium! I am currently pregnant and have been prescribed 400 mg of magnesium. Previously, I took Natural Vitality, CALM, but it caused me diarrhoea even with a half dose. I also tried citrate, but that upset my stomach too. My doctor confirmed that these forms aren’t absorbed well by me. The best magnesium for absorption is glycinate/bisglycinate, which I now take as it comes from organic vegetables and seeds. This option has no side effects, and I've forgotten about leg cramps and insomnia. I take 1 capsule twice a day, and they are easy to swallow. I highly recommend this supplement!
Heartburn details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
We explored the impact of a new treatment, Marial®, on patients suffering from gastroesophageal reflux disease (GERD). In a large survey involving 56 gastroenterological offices across Italy, patients were treated with either proton pump inhibitors (PPIs), a combination of PPIs and an additional remedy, or the Marial® formulation containing magnesium alginate. The results showed that both Marial® and the combination therapy significantly reduced heartburn symptoms, with Marial® proving to be more effective than the combination. Overall, patients reported a marked improvement in their GERD-related symptoms.
9
Very effective
Most Useful Review
I absolutely love this magnesium! It’s easy to take, and I’m pleased it doesn’t cause any discomfort or heartburn, making it my top choice.
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 10 Reviews
8.5
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9
Migraines managed well
Most Useful Review
13 people found this helpful
This product is fantastic! It has alleviated my migraine headaches and improved my sleep. I know it works because I ran out and missed a couple of days, resulting in a migraine and sleepless nights. I take two capsules before bed every night, and it works wonderfully!
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
9
No nausea experienced
Most Useful Review
I’m definitely repurchasing these as I’ve been taking them at night to aid my sleep. They don’t have the mineral-y smell that some capsules do, and crucially, I haven’t experienced any nausea when taking them without food. I’ve been sleeping more soundly and find the price great for the quantity provided.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
7.5
Fewer cramps noted
Most Useful Review
10 people found this helpful
Feeling significantly better! I had been experiencing numerous muscle cramps in my lower legs and feet, particularly at night, which was dreadful. Since I started taking this supplement, the frequency of muscle cramps has notably decreased! I realised I wasn't obtaining enough magnesium from my diet alone. Additionally, taking it before bed helps me relax and calms me, enhancing my sleep quality.
Cardiovascular Disease details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Good
Based on 5 Reviews
8.4
8
Magnesium's impact on heart health
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
9
Reduced heart disease risk
Most Useful Review
3 people found this helpful
Magnesium is an essential trace element that we obtain solely through food, capable of reducing the risk of ischaemic heart disease and arterial hypertension, as well as preventing strokes. It normalises blood pressure, alleviates muscle spasms, and prevents blood vessel constriction, while also serving as a natural anti-stress agent. Magnesium has a calming effect on the nervous system during periods of anxiety and depression, protecting it from stress. By increasing magnesium intake, one can reduce the frequency and intensity of migraines, enhancing overall cardiovascular health.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 6 Reviews
8.4
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
9
Reduced irritability
Most Useful Review
Magnesium is involved in over 300 enzymatic processes and is essential for our well-being. It depletes quickly, especially under stress. I experienced muscle cramps and insomnia, leading to irritability. After starting these supplements, my cramps and pain disappeared, and I resumed sleeping properly by 11 PM. I have more energy and, fortunately, my irritability has significantly diminished. My family has noticed the positive change too.
Adrenal Gland Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.3
7.5
Recommended for breastfeeding
Most Useful Review
7 people found this helpful
Good vitamins; the dosage of magnesium glycine is correctly selected. I began taking them on my doctor's recommendation to support my adrenal gland as I am breastfeeding. The doctor advised using them throughout this period. I take two capsules daily between meals. The capsules are medium-sized and easy to swallow. The product's quality is top-notch!
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Good
Based on 10 Reviews
8.3
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9
Calmer with magnesium
Most Useful Review
6 people found this helpful
This magnesium has transformed my sleep! I feel calmer, even with my kids’ antics. It has improved my sleep quality and overall mood. I’ve ordered several more!
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
9
Essential for well-being
Most Useful Review
3 people found this helpful
Magnesium is vital for human health, with 60% found in bones. Chelated forms, such as Magnesium Glycinate, are absorbed faster and are gentle on digestion. It is prescribed for headaches, seizures, anxiety, and depression. I take 2 capsules at night and recommend this quality product.
Leg Cramps details
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 41 Reviews
8.3
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
9
Improved leg cramps
Most Useful Review
238 people found this helpful
I take this drug as part of a complex therapy for the treatment of insulin resistance and estrogen dominance, aiming to rectify uterine myoma with my doctor. Magnesium is crucial in my daily intake. Following its use, my bowel movements improved dramatically, becoming calmer and smoother, as if leg cramps had vanished. The glycinate form is perfect for addressing the nervous system. I highly recommend it!
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.2
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
9
No abdominal pain
Most Useful Review
Excellent product! It has no abdominal discomfort, a large number of pills, and they are relatively easy to swallow. Highly recommended!
Frozen Shoulder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.2
7.5
Improved muscle pain
Most Useful Review
This has better absorption than other types. I’ve noticed I no longer have neck and shoulder muscle pain, and it has also helped enhance my mood.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 32 Reviews
8.2
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
9
Sleep improvement
Most Useful Review
589 people found this helpful
I found the magnesium glycinate from Naturelo to be effective. After just two capsules, I slept soundly, unlike when I tried KAL’s version, which didn't work for my insomnia. I highly recommend it!
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Good
Based on 29 Reviews
8.2
8
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
9
Significant pain relief
Most Useful Review
115 people found this helpful
I never noticed the effects of vitamins before, but these exceeded my expectations. I started taking Magne B6 after experiencing leg muscle cramps, which would interrupt my sleep. Within a week, the pain diminished, and after 2-3 weeks, it was gone entirely. I began to sleep better, was less anxious over trivial matters, and my mood improved significantly. Friends noticed the changes in me. I only take these vitamins, and they are the first that haven't caused any discomfort. I take 2 tablets each morning and evening.
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.1
8
Magnesium protects against bone erosion
We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
7.5
Effective anti-arthritis
Most Useful Review
Really good product quality with a convenient size for use and good ingredients. The packaging is convenient, and it has good anti-arthritis benefits and aids muscle recovery.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 30 Reviews
8.1
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
9
Pain relief success
Most Useful Review
115 people found this helpful
I never felt the effect of vitamins, but these exceeded my expectations. After experiencing leg muscle cramps, I was advised by the pharmacy to take Magne B6. Within a week, my pain decreased, and after 2-3 weeks, it completely vanished. I began to sleep better, my mood improved, and people around me noticed the changes. I have no discomfort while taking these vitamins, which is unusual for me as I dislike the aftertaste associated with most. I take two tablets in the morning and two in the evening.
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 22 Researches
6.8
USERS' SCORE
Good
Based on 12 Reviews
8.1
9
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
9
Effective for constipation
Most Useful Review
4 people found this helpful
I have been taking this supplement for a month now, as I wanted to see if it made a difference. Since my VSG surgery, I have struggled with constipation. Someone suggested magnesium, which I have been taking daily. It has significantly helped me with bowel movements; I now go every day instead of every 3-7 days. This has been a major improvement for me!
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.1
9
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
9
Sleep improvement
Most Useful Review
I love this product. Since going through menopause, I've suffered from severe insomnia. My doctor suggested magnesium, and I discovered this food-based version. It’s precisely what I needed; I take 400 mg before bed, and it helps me more than anything, including melatonin.
Premenstrual Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 14 Reviews
8.1
7.5
Helps with PMS
Most Useful Review
2 people found this helpful
I found this magnesium quite effective, particularly in alleviating my PMS symptoms. It has been beneficial for my overall well-being.
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 7 Reviews
8
8
Magnesium enhances postoperative recovery
We conducted a study to see how magnesium sulfate could influence recovery after total knee arthroplasty in older patients. Using a double-blind, randomized control design, 148 patients were split into two groups: one received magnesium sulfate while the other got saline.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
9
Highly effective
Most Useful Review
Great quality product! The ingredients are perfectly selected, and there were no allergies or negative reactions. The large package size lasts a long time, and the capsules are of average size with a neutral taste. I noticed improvements in intestinal function and metabolism within a week. My nervous system feels more stable and I am less anxious. I have complete faith in the effectiveness of this vitamin.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 7 Reviews
8
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
9
Pleasant side effects
Most Useful Review
2 people found this helpful
This is a good chelate formula I started taking for a doctor-prescribed course. Its pleasant side effects include helping to cope with chronic fatigue! One minor drawback is that the capsules are a bit large, making them challenging to swallow at times.
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Good
Based on 3 Reviews
8
9
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
9
Supports heart health
Most Useful Review
7 people found this helpful
Chelated magnesium can greatly enhance your life quality, alleviating irritability and fatigue. It's essential for athletes and those in sedentary roles, as it supports heart functions and helps prevent heart attacks. Its role in stress resistance and for pregnant women, particularly in the first trimester, is significant.
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 99 Reviews
7.9
7
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
9
Restores sleep function
Most Useful Review
227 people found this helpful
Excellent! This magnesium has greatly improved my sleep quality. I wake up feeling lighter and more cheerful, and I'm able to fall asleep easily. Highly recommend this magnesium for anyone looking for a solution to sleep issues.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.8
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
9
Great overall health
Most Useful Review
2 people found this helpful
This brand lives up to its claims about supporting healthy bones, heart, and relieving stress. Personally, I’ve experienced improved sleep as it calms both my mind and muscles, significantly enhancing my overall health.
Vertigo details
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.3
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.7
9.5
We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.
After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.
Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.
After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.
Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.
10
Vertigo relief attained
Most Useful Review
6 people found this helpful
Vertigo: gone! I battled with vertigo for some time and couldn't find any solutions. I consulted several doctors and underwent various tests, yet no one could provide an explanation. Then I stumbled upon a blog suggesting that vertigo might indicate a magnesium deficiency. Consequently, I began taking magnesium glycinate and I haven't experienced vertigo since. It’s been four years.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.6
8
Magnesium scaffold shows promising results
We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
7
Lowers blood pressure
Most Useful Review
1 people found this helpful
I noticed a positive effect on my blood pressure after discovering the link between magnesium deficiency and hypertension. Initially on the verge of high blood pressure, it has stabilised around 130, which is quite nice!
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.5
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
10
Migraine relief
Most Useful Review
13 people found this helpful
This product is fantastic! It has helped my migraine headaches and my sleeping difficulties. I know it works because when I ran out and missed a couple of days, I suffered a migraine and had trouble sleeping. I take two capsules before bed every night and it works like a charm!
Anxiety details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.9
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.1
8
Magnesium treats anxiety in MS
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
9
Holy grail supplement
Most Useful Review
336 people found this helpful
I rarely write reviews, but this supplement is incredible! I’ve tried various magnesium products, but this is by far the best. I take two capsules before bed, and my anxiety and stress levels have significantly decreased, allowing me to fall asleep easily and wake up refreshed. It has also relieved my muscle cramps due to stress. GREAT PRODUCT!
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.9
USERS' SCORE
Moderately Good
Based on 4 Reviews
7
9.5
We observed the intriguing connection between Meniere's disease (MD) and migraine-related dizziness in our study of a 5-year-old girl. She experienced a six-month struggle with left-sided hearing loss, which evolved into daily bouts of vertigo, headaches, and vomiting, fulfilling the criteria for definite MD.
After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.
This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.
After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.
This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.
9
Dizziness eliminated
Most Useful Review
I purchased this supplement for my husband, who has been taking it for over a month. He no longer experiences dizziness, and his sleep has improved significantly. The capsules are large but easy to swallow, and the packaging is dark plastic, which protects them from sunlight. It has no taste or smell, and the dosage is good—there’s plenty, so it will last a long time.
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.9
9
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
9
Reduced A1C levels
Most Useful Review
5 people found this helpful
After being diagnosed with pre-diabetes and hormonal imbalances, my doctor recommended Magnesium Glycinate. I prefer the Chelate form and couldn't be more pleased with my choice. These capsules are tasteless and easy to take, with no stomach issues to report. Since I started taking them, my A1C levels have improved alongside diet changes. I highly recommend this supplement for anyone in a similar position.
