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Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 90 mg Ferrous Bisglycinate)(Ferrochel™)
18 mg
100%
The product is found useful for the following medical conditions
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Good
Based on 82 Reviews
8.9
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Most Relevant Research
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
9.5
Natural alternative work
Most Useful Review
Worked well Alone and With Ferret's Iron. In early 2013, I had low iron affecting my hair health. After struggling with prescription iron due to severe side effects, I researched alternatives and found these pills. Taking them before a blood test, I experienced no stomach issues, and my blood test revealed my iron levels improved significantly. I now take these along with Ferrett's Iron Supplement and I'm delighted with my progress. They are a big help in building my iron levels.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 36 Reviews
8.9
8
CUR-PDT triggers ferroptosis in RA
CUR-PDT induces ferroptosis of RA-FLS via the Nrf2/xCT/GPX4 pathway to inhibit proliferation in rheumatoid arthritis.
Most Relevant Research
We examined how curcumin-mediated photodynamic therapy (CUR-PDT) induces a specific type of cell death called ferroptosis in fibroblast-like synoviocytes from rheumatoid arthritis patients.
Using a rat model, we monitored joint swelling and inflammation while analyzing key proteins involved in this process. The results indicated that CUR-PDT successfully reduces harmful cell growth and inflammation in RA cells by targeting the Nrf2-xCT-GPX4 pathway.
This finding emphasizes the potential of CUR-PDT as a treatment strategy in managing rheumatoid arthritis.
Using a rat model, we monitored joint swelling and inflammation while analyzing key proteins involved in this process. The results indicated that CUR-PDT successfully reduces harmful cell growth and inflammation in RA cells by targeting the Nrf2-xCT-GPX4 pathway.
This finding emphasizes the potential of CUR-PDT as a treatment strategy in managing rheumatoid arthritis.
9.5
Reduced hair loss
Most Useful Review
Suffering from iron deficiency anaemia, I take iron supplements when I notice more hair than usual on my comb. This product has been effective, so I rate it five stars. It has no harsh effects on my digestive system, and next time, I plan to order an iron complex with vitamin C from the same manufacturer.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.8
USERS' SCORE
Good
Based on 71 Reviews
8.9
9
Effect of iron on dizziness relief
Critical iron deficiency anemia with record low hemoglobin: a case report.
Most Relevant Research
We studied the impact of iron treatment on dizziness experienced by a 42-year-old woman suffering from severe iron deficiency anemia due to menometrorrhagia. Throughout her hospital stay, she received blood transfusions and intravenous iron, which played a critical role in addressing her debilitating symptoms.
Remarkably, despite her initial critically low hemoglobin levels, she managed to remain hemodynamically stable. By the end of her treatment, her symptoms of fatigue and dizziness had resolved, allowing her to return to her normal activities before discharge. This case highlights an important connection between iron levels and dizziness, illustrating that replenishing iron can significantly alleviate dizzy spells linked to anemia.
Our findings underscore how crucial it is to address iron deficiency effectively, as it can prevent serious complications and improve overall quality of life for patients experiencing symptoms like dizziness.
Remarkably, despite her initial critically low hemoglobin levels, she managed to remain hemodynamically stable. By the end of her treatment, her symptoms of fatigue and dizziness had resolved, allowing her to return to her normal activities before discharge. This case highlights an important connection between iron levels and dizziness, illustrating that replenishing iron can significantly alleviate dizzy spells linked to anemia.
Our findings underscore how crucial it is to address iron deficiency effectively, as it can prevent serious complications and improve overall quality of life for patients experiencing symptoms like dizziness.
10
Dizziness eliminated
Most Useful Review
I switched from 36mg of another iron product to this one due to concerns about overdosing. Since starting the 36mg dosage, my lower eyelids changed colour and my dizziness dissipated, suggesting my anaemia has resolved. Heme iron is crucial for absorption, so I’ll keep taking this supplement for my health.
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 6 Reviews
8.8
7
Iron boosts mental health in pregnancy
Associations between iron status and psychosocial wellbeing among pregnant women in Cape Coast, Ghana: a longitudinal study.
Most Relevant Research
We examined how changes in iron levels during pregnancy relate to anxiety and overall wellbeing. The study followed pregnant women in Cape Coast, Ghana, tracking their iron status and psychological health throughout the first, second, and third trimesters.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
9.5
Reduced anxiety symptoms
Most Useful Review
I'm pleased with my new hair! I experienced hair loss due to iron deficiency, which is why I chose this supplement, as it has a commendable composition. The capsules are easy to swallow with water. I took one capsule daily for three months, and the packaging was ideal—should I need iron again, I can resume immediately without delay. After six months, I noticed significant growth of small new hairs. Additionally, I struggled with fatigue, which I attributed to depression and anxiety. After the iron course, those issues resolved. I also took iron with vitamin C from NOW Foods. The photo shows my hair's growth, which continues to flourish and resembles bangs now! 😅
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.3
USERS' SCORE
Good
Based on 8 Reviews
8.8
9
Iron nanoparticle imaging efficacy
A subtype specific probe for targeted magnetic resonance imaging of M2 tumor-associated macrophages in brain tumors.
Most Relevant Research
We explored the potential of using a specific type of iron nanoparticle to target and image a distinct group of immune cells known as M2 tumor-associated macrophages (TAMs) in brain tumors. These M2 TAMs can promote tumor growth and understanding their behavior could offer insights for better cancer treatments.
In our research, we developed a unique magnetic resonance imaging (MRI) probe composed of ultrafine iron oxide nanoparticles, which are small enough to avoid non-specific action in the body. We included a special peptide that actively seeks out M2 TAMs, allowing us to visualize them more clearly in mouse models of glioblastoma, a common and aggressive type of brain cancer.
The results were promising. The targeted nanoparticles showed a significant increase in accumulation within the tumors compared to standard nanoparticle formulations. This means that the M2-specific MRI probe provided a noticeable contrast in imaging, helping us differentiate areas of interest in the brain tumor environment better than conventional methods.
By demonstrating how effectively these iron nanoparticles can target specific immune cells, our study lays the groundwork for future research surrounding their use in cancer diagnostics and possibly in therapy. This could lead to improved strategies for tracking and altering the tumor environment as cancer progresses.
In our research, we developed a unique magnetic resonance imaging (MRI) probe composed of ultrafine iron oxide nanoparticles, which are small enough to avoid non-specific action in the body. We included a special peptide that actively seeks out M2 TAMs, allowing us to visualize them more clearly in mouse models of glioblastoma, a common and aggressive type of brain cancer.
The results were promising. The targeted nanoparticles showed a significant increase in accumulation within the tumors compared to standard nanoparticle formulations. This means that the M2-specific MRI probe provided a noticeable contrast in imaging, helping us differentiate areas of interest in the brain tumor environment better than conventional methods.
By demonstrating how effectively these iron nanoparticles can target specific immune cells, our study lays the groundwork for future research surrounding their use in cancer diagnostics and possibly in therapy. This could lead to improved strategies for tracking and altering the tumor environment as cancer progresses.
9.5
Itching resolved
Most Useful Review
Recently, even a single hair touching my face made me itchy, which worried me. I discovered that iron deficiency can cause itching and quickly bought this mineral supplement. I adore coffee, but the tannins in it inhibit iron absorption. Initially, I took double the amount of iron, but I learned that too much can harm the digestive tract, liver, heart, and brain, so I reduced my dosage. Since I began taking it, the itching disappeared. I plan to better organise my meals with iron in mind.
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.8
9.5
No side effects noted
Most Useful Review
I recommend it works! I've purchased this iron multiple times, and it's effective. The price and quality are decent, and it doesn't cause any side effects. My ferritin levels rose to 82 in three months, and hair loss has ceased. I've seen an improvement in my Chronic Fatigue Syndrome and nail condition. If my comment proves useful, I would appreciate your feedback. Thanks!
High Cholesterol details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 6 Reviews
8.8
8
Iron's influence on cholesterol levels
Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults.
Most Relevant Research
We examined the relationship between essential and toxic elements in the plasma of institutionalized older adults and their cholesterol levels. Focusing on a group of 149 Brazilian seniors living in nursing homes, our goal was to understand how these elements influence lipid profiles and blood sugar levels.
Our findings indicated that lower concentrations of certain chemical elements, particularly iron, seemed to protect against increasing total cholesterol levels. We observed non-linear effects of iron, along with other elements like barium and copper, on triglyceride levels. Notably, when the concentration of these elements fell below a certain threshold, we found an associated decrease in total cholesterol.
These results suggest that monitoring the levels of these essential and toxic elements could be vital in preventing dyslipidemia—a condition characterized by abnormal lipid levels—and managing clinical interventions in older adults. The significant role of iron in influencing cholesterol levels emphasizes the need for continued research and screening in this population, to ensure that their health remains a top priority.
Our findings indicated that lower concentrations of certain chemical elements, particularly iron, seemed to protect against increasing total cholesterol levels. We observed non-linear effects of iron, along with other elements like barium and copper, on triglyceride levels. Notably, when the concentration of these elements fell below a certain threshold, we found an associated decrease in total cholesterol.
These results suggest that monitoring the levels of these essential and toxic elements could be vital in preventing dyslipidemia—a condition characterized by abnormal lipid levels—and managing clinical interventions in older adults. The significant role of iron in influencing cholesterol levels emphasizes the need for continued research and screening in this population, to ensure that their health remains a top priority.
9.5
Fantastic results
Most Useful Review
Amazing! I’ve struggled with anemia for years, feeling fatigued often. After realising I needed iron, I tried the usual store brands, which caused stomach issues. Switching to this product was transformative; I had no side effects within days and felt fantastic. The price and quality can't be beaten. Thank you, Iherb, for your excellent products!
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Allergy management in iron treatments
From diagnosis to desensitization in immediate hypersensitivity reactions to both oral and parenteral iron salts.
Most Relevant Research
We examined the rise of hypersensitivity reactions (HRs) linked to iron agents, especially as their usage in treating iron deficiency has increased. In this study, we evaluated the clinical features of patients who experienced immediate hypersensitivity reactions (IHRs) to both oral and intravenous (IV) iron preparations.
Our analysis included the medical records of 96 patients with a history of these reactions. Among them, 47 had reactions to oral iron, while 49 reacted to IV iron. We conducted skin-prick tests with various iron salts, but found that these tests weren't very helpful for diagnosing IHRs. In fact, only a small percentage showed a positive reaction.
Interestingly, we noted that patients who were sensitive to IV iron experienced more severe reactions, including cases of anaphylaxis. Despite the challenges in diagnosing these allergies, we successfully conducted desensitization treatments for 15 patients needing iron, specifically using ferric carboxymaltose. This approach proved to be safe and effective, marking an important option for patients requiring iron therapy despite their hypersensitivity.
Our analysis included the medical records of 96 patients with a history of these reactions. Among them, 47 had reactions to oral iron, while 49 reacted to IV iron. We conducted skin-prick tests with various iron salts, but found that these tests weren't very helpful for diagnosing IHRs. In fact, only a small percentage showed a positive reaction.
Interestingly, we noted that patients who were sensitive to IV iron experienced more severe reactions, including cases of anaphylaxis. Despite the challenges in diagnosing these allergies, we successfully conducted desensitization treatments for 15 patients needing iron, specifically using ferric carboxymaltose. This approach proved to be safe and effective, marking an important option for patients requiring iron therapy despite their hypersensitivity.
9.5
Increased iron levels
Most Useful Review
I had an iron deficiency, but since I began taking iron supplements, my levels have improved. I have not encountered any side effects or allergies, and the quality of the ingredients appears to provide significant benefits to my body. If this review has been helpful, please consider leaving a rating; I would appreciate it.
Back Pain details
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
HP alleviates iron-induced back pain
Inhibits Iron Overload-Induced Oxidative Stress through Activation of Signaling in a Rat Model of Lumbar Spinal Stenosis.
Most Relevant Research
We investigated how a substance called HP influences iron-related oxidative stress and its connection to back pain in a common condition known as lumbar spinal stenosis (LSS). LSS causes significant discomfort and disability, particularly for older adults, primarily due to hypertrophy of the ligamentum flavum, which can be exacerbated by oxidative stress stemming from imbalanced iron levels.
Our study involved exposing spinal cord neuron cultures to iron before treatment with HP at varying concentrations. We assessed the cells' health using tests to measure viability and cell damage. Additionally, in a rat model of LSS, we provided different doses of HP and monitored the effects over several weeks. The results were compelling: HP not only protected neurons from iron-induced damage but also promoted cellular health by boosting antioxidant defenses through a pathway known as NRF2.
Over the course of our observations, we noted significant reductions in both inflammation and oxidative stress markers in the rats treated with HP. This regulation of excess iron appeared to alleviate mechanical allodynia—a condition causing painful responses to light touch—and improved the overall functionality of the affected rats.
Our findings suggest that HP therapy may offer a promising approach to manage iron-related oxidative stress in LSS and the associated back pain, indicating a new avenue for treatment that could enhance quality of life.
Our study involved exposing spinal cord neuron cultures to iron before treatment with HP at varying concentrations. We assessed the cells' health using tests to measure viability and cell damage. Additionally, in a rat model of LSS, we provided different doses of HP and monitored the effects over several weeks. The results were compelling: HP not only protected neurons from iron-induced damage but also promoted cellular health by boosting antioxidant defenses through a pathway known as NRF2.
Over the course of our observations, we noted significant reductions in both inflammation and oxidative stress markers in the rats treated with HP. This regulation of excess iron appeared to alleviate mechanical allodynia—a condition causing painful responses to light touch—and improved the overall functionality of the affected rats.
Our findings suggest that HP therapy may offer a promising approach to manage iron-related oxidative stress in LSS and the associated back pain, indicating a new avenue for treatment that could enhance quality of life.
9.5
Ferritin improvement
Most Useful Review
I purchased this as I am anaemic. Following the use of this supplement, my ferritin levels increased to normal after my doctor-prescribed iron had failed. I hope this helps you too. Please press the good button if you find it helpful.
Blood Clot details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 89 Reviews
8.7
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
Most Relevant Research
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
8.3
Improved energy levels
Most Useful Review
I have always had low iron levels in my blood, affecting my health with constant weakness and fatigue. Headaches and low blood pressure plagued me. After taking this in the morning, waking up became easier, and I fell asleep more quickly at night. My weakness vanished, and my blood pressure normalised. I recommend it to everyone.
Cancer details
SCIENTIFIC SCORE
Likely Very Effective
Based on 10 Researches
9
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
SPIO improves lymph node detection
Use of superparamagnetic iron oxide for sentinel lymph node detection following neoadjuvant systemic therapy. A systematic review and meta-analysis.
Most Relevant Research
We explored the effectiveness of superparamagnetic iron oxide (SPIO) in detecting sentinel lymph nodes in breast cancer patients who had undergone neoadjuvant systemic therapy before surgery. This study included a systematic review of multiple databases and focused on comparing SPIO to the standard methods involving radioisotope and blue dye.
Our findings highlight that SPIO successfully identified sentinel lymph nodes in about 98.1% of cases, while the standard method achieved a detection rate of 94.6%. When examining the number of lymph nodes retrieved, SPIO demonstrated superior performance, with an average of 2.26 nodes detected compared to 1.86 with the conventional approach.
The overall quality of the studies reviewed was considered good, indicating that we can reliably say SPIO can be safely and effectively adopted in clinical practice for these patients. This suggests a promising alternative in medical settings, where identifying lymph nodes accurately is crucial for treatment planning.
Our findings highlight that SPIO successfully identified sentinel lymph nodes in about 98.1% of cases, while the standard method achieved a detection rate of 94.6%. When examining the number of lymph nodes retrieved, SPIO demonstrated superior performance, with an average of 2.26 nodes detected compared to 1.86 with the conventional approach.
The overall quality of the studies reviewed was considered good, indicating that we can reliably say SPIO can be safely and effectively adopted in clinical practice for these patients. This suggests a promising alternative in medical settings, where identifying lymph nodes accurately is crucial for treatment planning.
9.5
Caution advised
Most Useful Review
It's essential for women, so I consider it indispensable. However, it is a preferred food for cancer, so I must be cautious about how much I consume.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 16 Reviews
8.7
7
Iron boosts fatigue symptoms
The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
Most Relevant Research
We explored the effects of iron supplementation on individuals suffering from iron deficiency, specifically looking at its impact on symptoms like chronic fatigue syndrome (CFS). This was done through a well-structured study involving 176 blood donors who were iron deficient, with a randomized controlled trial design.
Participants were assigned to receive either intravenous iron or oral iron supplements. Over an 8-12 week period, we assessed changes in symptoms related to iron deficiency, including CFS, restless legs syndrome (RLS), sleeping disorders, and overall quality of life.
The results indicated that iron supplementation may significantly improve the symptoms associated with iron deficiency among blood donors. By addressing the iron deficiency, we noted improvements not only in fatigue but also in wellbeing, confirming that targeted iron treatment can be beneficial for those struggling with chronic fatigue linked to low iron levels. This is an exciting finding for both clinicians and patients, shedding light on a relatively simple intervention that can enhance quality of life.
Participants were assigned to receive either intravenous iron or oral iron supplements. Over an 8-12 week period, we assessed changes in symptoms related to iron deficiency, including CFS, restless legs syndrome (RLS), sleeping disorders, and overall quality of life.
The results indicated that iron supplementation may significantly improve the symptoms associated with iron deficiency among blood donors. By addressing the iron deficiency, we noted improvements not only in fatigue but also in wellbeing, confirming that targeted iron treatment can be beneficial for those struggling with chronic fatigue linked to low iron levels. This is an exciting finding for both clinicians and patients, shedding light on a relatively simple intervention that can enhance quality of life.
9.5
Fatigue lifted completely
Most Useful Review
I consistently struggle with low haemoglobin levels, reflecting noticeably on my health and causing constant tiredness. The iron in pharmacies is expensive and often of questionable quality. After three months of taking this vitamin, my fatigue has vanished, and blood tests revealed excellent results! I wholeheartedly recommend it!
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6
USERS' SCORE
Good
Based on 90 Reviews
8.7
9
Iron supplements reduce donor deferral
Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors.
Most Relevant Research
We assessed how iron supplementation impacts blood donors who may suffer from low iron levels. Our analysis included thirty studies with nearly 4,700 participants, focusing on the differences between those receiving iron and those who didn’t.
We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.
These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.
These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
9.5
No constipation noted
Most Useful Review
Iron is an essential mineral impacting energy production, as well as the immune and nervous systems. It is a key component of haemoglobin, the molecule that transports oxygen to body cells. NOW utilises Ferrochel Iron Bisglycinate as clinical studies indicate it is well absorbed and gentle on the body, not causing constipation.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 3 Reviews
8.7
7
Iron deficiency impacts sleep disorders
Iron Deficiency and Restless Sleep/Wake Behaviors in Neurodevelopmental Disorders and Mental Health Conditions.
Most Relevant Research
We observed a strong connection between iron deficiency (ID) and restlessness impacting sleep in children with neurodevelopmental disorders such as ADHD and autism spectrum disorders (ASD). In a clinic focused on sleep/wake behaviors, we found that a staggering 94% of the 199 patients evaluated had ID, and many struggled with insomnia and sleep disorders.
Notably, patients with a family history of ID faced heightened risks of experiencing sleep disturbances, including restless legs syndrome (RLS) and chronic insomnia. For instance, in children with ADHD, the odds of insomnia increased significantly with a family background of ID. Similarly, those with ASD also showed increased odds for various sleep issues tied to a familial history of ID.
These insights highlight an urgent need for integrating comprehensive evaluations that address both iron levels and family sleep history. By doing so, we can better understand and address the sleep challenges faced by these children and adolescents, and potentially improve their quality of life.
Notably, patients with a family history of ID faced heightened risks of experiencing sleep disturbances, including restless legs syndrome (RLS) and chronic insomnia. For instance, in children with ADHD, the odds of insomnia increased significantly with a family background of ID. Similarly, those with ASD also showed increased odds for various sleep issues tied to a familial history of ID.
These insights highlight an urgent need for integrating comprehensive evaluations that address both iron levels and family sleep history. By doing so, we can better understand and address the sleep challenges faced by these children and adolescents, and potentially improve their quality of life.
9.5
Improved energy
Most Useful Review
I was feeling low and tired, so I decided to try this vitamin. I noticed a difference in my energy and mood within a few days. I feel more energetic and alert. It's very effective in combating insomnia as well; it may seem expensive, but it's worth it.
Migraine details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 6 Reviews
8.7
8
Iron's impact on migraine relief
Iron Deficiency Anemia and Migraine: A Literature Review of the Prevalence, Pathophysiology, and Therapeutic Potential.
Most Relevant Research
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.
Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.
However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.
However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
9.5
Alleviated migraines
Most Useful Review
I began taking it after being diagnosed with anaemia during a health check. With 1-2 tablets of 18mg daily, symptoms like dizziness, lightheadedness, and fatigue improved immediately. Remarkably, the migraine headaches I had suffered from diminished, and my use of painkillers reduced. It's surprising that iron intake can lead to such significant improvements in my health.
Tinnitus details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.7
9.5
Immediate tinnitus relief
Most Useful Review
I experience ringing in my ears and lightheadedness almost daily, possibly due to anaemia. Although I was conscious of iron supplements, my tinnitus persisted. I was introduced to this supplement and was somewhat sceptical initially... Since I started taking it, both my tinnitus and lightheadedness have vanished. I'm astonished by the rapid effect.
Ulcer details
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9
USERS' SCORE
Good
Based on 4 Reviews
8.7
9
Iron therapy may cause ulcers
Gastric Ulcer From Prolonged Oral Iron Therapy: A Case Report and Literature Review.
Most Relevant Research
We explored a case involving a 66-year-old woman who developed a gastric ulcer after using oral iron supplements for an extended period. Iron therapy is commonly prescribed for treating iron deficiency anemia, but it often comes with gastrointestinal side effects.
In this instance, the patient had a history of GI bleeding and other medical conditions, which might have contributed to her increased risk. While gastrointestinal issues with iron supplements are not unusual, having a gastric ulcer as a direct result is rare, and only a handful of similar cases have been reported in medical literature.
Upon conducting endoscopic and histopathological evaluations, we identified iron deposits in the ulcer bed, confirming that the iron therapy was indeed linked to her gastric ulcer. After stopping the oral iron supplements, her symptoms resolved, highlighting the need for careful patient monitoring during iron therapy to prevent serious complications like ulcers.
Our findings emphasize the importance of recognizing and managing the potential adverse effects of oral iron to maintain a safe and effective treatment regimen for iron deficiency anemia.
In this instance, the patient had a history of GI bleeding and other medical conditions, which might have contributed to her increased risk. While gastrointestinal issues with iron supplements are not unusual, having a gastric ulcer as a direct result is rare, and only a handful of similar cases have been reported in medical literature.
Upon conducting endoscopic and histopathological evaluations, we identified iron deposits in the ulcer bed, confirming that the iron therapy was indeed linked to her gastric ulcer. After stopping the oral iron supplements, her symptoms resolved, highlighting the need for careful patient monitoring during iron therapy to prevent serious complications like ulcers.
Our findings emphasize the importance of recognizing and managing the potential adverse effects of oral iron to maintain a safe and effective treatment regimen for iron deficiency anemia.
9.5
Improved PMS symptoms
Most Useful Review
Anemia has decreased. I purchased this as a supplement to boost my iron intake, which my regular diet doesn’t provide due to severe PMS. The capsules resemble iron, making me feel confident about their efficacy. They are small and easy to swallow. Since I began taking this, my PMS symptoms have improved. I was particularly delighted to discover that my mouth ulcers have also ceased.
Urinary Tract Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Significant improvement
Most Useful Review
The effect was unexpected - my haemoglobin rose from 90 to 127 in just one month, a change not seen in the past three years. I experienced no reactions from my gastrointestinal tract.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
Lactoferrin shows promise for acne
Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: an exploratory study.
Most Relevant Research
We explored the potential benefits of oral bovine lactoferrin as a dietary supplement for individuals struggling with mild to moderate acne vulgaris. This study involved 43 young participants who took chewable lactoferrin tablets twice a day for eight weeks.
By the end of the study, we observed promising results. Participants experienced an average reduction in acne lesions. Specifically, there was a 20% decrease in inflammatory lesions, a more significant 23.5% reduction in non-inflammatory lesions, and an overall improvement in total lesion counts of 22.5%. Notably, around 77% of the subjects saw a decrease in their total lesion counts, indicating that lactoferrin may have a positive effect.
Importantly, we found that lactoferrin was well tolerated, with no reported adverse effects related to the supplement during the trial. Although our study had some limitations due to its open-label design without a control group, the results encourage further research into lactoferrin's efficacy for acne treatment, particularly through randomized controlled trials.
By the end of the study, we observed promising results. Participants experienced an average reduction in acne lesions. Specifically, there was a 20% decrease in inflammatory lesions, a more significant 23.5% reduction in non-inflammatory lesions, and an overall improvement in total lesion counts of 22.5%. Notably, around 77% of the subjects saw a decrease in their total lesion counts, indicating that lactoferrin may have a positive effect.
Importantly, we found that lactoferrin was well tolerated, with no reported adverse effects related to the supplement during the trial. Although our study had some limitations due to its open-label design without a control group, the results encourage further research into lactoferrin's efficacy for acne treatment, particularly through randomized controlled trials.
8.8
Effective for acne
Most Useful Review
I purchased this supplement as I've been informed that iron can help with the significant acne on my chin, which I believe is caused by wearing a mask and hormonal imbalances. Within a week of starting the tablets, the red acne began to improve. I was initially startled to notice that my stools turned black, as mentioned by others. Nonetheless, one tablet a day suffices and proves effective for my acne, so I intend to continue taking it.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Significant improvement
Most Useful Review
I have congenital anaemia, which causes dizziness and blurred vision. After taking this supplement for a few days, I observed a significant improvement.
Bruise details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 5 Reviews
8.6
7
Iron's role in rhizome discoloration
Study on the formation mechanism of blackening in damaged lotus rhizome epidermis: Effects of polyphenols and iron.
Most Relevant Research
We explored how iron interacts with polyphenols in lotus rhizomes, specifically looking at how this combination affects bruising and the resulting discoloration. Our study revealed that when lotus rhizomes sustain bruises, the levels of total phenols decrease while the iron content significantly increases.
We found that certain polyphenols like dopa, gallocatechin, and catechin were present in the rhizomes. Interestingly, when combined with iron, these polyphenols led to noticeable darkening of the tissue, showcasing a clear link between iron and blackening. In a simulated environment, we were able to replicate these effects, confirming that iron plays a significant role under neutral conditions.
While we discovered ways to prevent this blackening, such as using ascorbic acid or EDTA, our main focus was the interaction between iron and dopa in bruised lotus rhizomes. This interaction seems to be the driving force behind the discoloration process. The insights from this research can help improve the storage methods for lotus rhizomes and support the industry's development.
We found that certain polyphenols like dopa, gallocatechin, and catechin were present in the rhizomes. Interestingly, when combined with iron, these polyphenols led to noticeable darkening of the tissue, showcasing a clear link between iron and blackening. In a simulated environment, we were able to replicate these effects, confirming that iron plays a significant role under neutral conditions.
While we discovered ways to prevent this blackening, such as using ascorbic acid or EDTA, our main focus was the interaction between iron and dopa in bruised lotus rhizomes. This interaction seems to be the driving force behind the discoloration process. The insights from this research can help improve the storage methods for lotus rhizomes and support the industry's development.
9.5
Improved bruise appearance
Most Useful Review
Before starting iron supplements, it's essential to check for any deficiency. Always take them with vitamin C and folic acid. Symptoms of iron deficiency include fatigue, skin issues, dizziness, and frequent bruises. I started with the smallest dosage, as the capsules are small and easy to swallow. I've been taking them for two weeks, and I can see that the blue circles under my eyes are less noticeable, which were caused by exhaustion. Bruises used to appear from light pressure on my skin, but that has since stopped. These are all positive effects so far; I plan to continue taking them.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 4 Reviews
8.6
7
Iron deficiency impacts heart failure
Impact of iron deficiency on congestion and postdischarge survival in patients recently hospitalised for decompensated heart failure: a multicentre, prospective, observational analysis of the FERIC-RO study.
Most Relevant Research
Our investigation focused on the impact of iron deficiency in patients with worsening chronic heart failure, seeking clarity on how it affects their condition and recovery. We enrolled 163 patients from multiple centers who were hospitalized for this serious health issue. By evaluating iron deficiency at discharge, we distinguished those affected by low iron levels and compared various health indicators between groups.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
8.8
Supports cardiovascular system
Most Useful Review
A reputable manufacturer of an excellent nutritional supplement that effectively supports immunity, provides added strength and energy, and aids the cardiovascular system.
Cold Sores details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Iron therapy reduces cold sore frequency
Response to replacement iron therapy in sideropenic individuals with recrudescent herpes labialis.
Most Relevant Research
We investigated how iron replacement therapy affects the occurrence of cold sores, also known as recurrent herpes labialis, in people with low iron levels, a condition known as sideropenia. In our study, ten patients with confirmed sideropenia and a history of cold sores took ferrous sulphate for three months.
Before starting the treatment, these individuals reported experiencing an average of 0.78 episodes of cold sores each month. After the iron therapy, this number significantly dropped to just 0.2 episodes monthly. Furthermore, we found that there was a noteworthy increase in serum ferritin levels, a marker indicative of iron status, after treatment.
The results suggest that iron therapy may play a significant role in reducing the frequency of cold sores for those affected by iron deficiency. These findings are intriguing and warrant further exploration into iron supplementation as a potential option for managing cold sores in individuals with low iron levels.
Before starting the treatment, these individuals reported experiencing an average of 0.78 episodes of cold sores each month. After the iron therapy, this number significantly dropped to just 0.2 episodes monthly. Furthermore, we found that there was a noteworthy increase in serum ferritin levels, a marker indicative of iron status, after treatment.
The results suggest that iron therapy may play a significant role in reducing the frequency of cold sores for those affected by iron deficiency. These findings are intriguing and warrant further exploration into iron supplementation as a potential option for managing cold sores in individuals with low iron levels.
9.5
Increased vitality
Most Useful Review
Excellent effect! My waist feels lighter and I wake up refreshed! I began taking this product on the advice of my acupuncture teacher due to concerns about my fertility and general coldness. After starting to take a tablet before bed, I experienced a remarkable change and no longer feel overly sleepy in the mornings. I had some initial stomach upset and unusual odour, but I’m glad I started this iron supplement. It has also lessened the dullness I usually feel around my lower body.
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8.6
9.5
Significant hair growth
Most Useful Review
I'm happy with my new hairs! I suffered from hair loss due to an iron deficiency. This supplement caught my attention as it has a good composition. It tastes just like a capsule, which is easy to swallow. After taking one capsule a day for three months, the benefits became noticeable after six months when I saw a lot of small new hairs on my head. I also experienced fatigue, which I thought was depression and anxiety. However, after taking iron, everything improved. It's important to note that I took iron with vitamin C from NOW Foods.
Gastritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.1
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Iron treatment impacts gastritis
Iron Pill-Induced Gastritis in a Pediatric Patient Taking Ferrous Sulfate Tablets.
Most Relevant Research
We examined a case involving an 11-year-old male who experienced adverse effects from taking oral ferrous sulfate tablets to treat iron deficiency anemia. Over two months of treatment, he developed gastritis, which was confirmed through histological analysis during an endoscopy.
The findings revealed iron deposits in the stomach lining, prompting a reassessment of his iron supplementation strategy. We switched him from tablets to a liquid form of iron, which seemed to be gentler on his system.
After four months, a repeat endoscopy indicated a remarkable improvement, with the histological signs of gastritis resolving. This case illustrates that while iron is necessary for treating anemia, the form in which it's administered can significantly impact side effects like gastritis.
The findings revealed iron deposits in the stomach lining, prompting a reassessment of his iron supplementation strategy. We switched him from tablets to a liquid form of iron, which seemed to be gentler on his system.
After four months, a repeat endoscopy indicated a remarkable improvement, with the histological signs of gastritis resolving. This case illustrates that while iron is necessary for treating anemia, the form in which it's administered can significantly impact side effects like gastritis.
10
No side effects
Most Useful Review
Excellent hardware! I have gastritis and the iron I've consumed previously had a significant effect on my stomach. Since I began taking it, I've felt great without any side effects or stomach pain. I highly recommend it.
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.6
8.8
Improved digestive health
Most Useful Review
Iron capsules are available in pharmacies, but they can have side effects on digestion, like heartburn and constipation. Although this medicine is beneficial for the digestive system, it can still result in black stools. It's better to combine iron pills with healthy food full of essential minerals. The Ferrochel Iron Glycinate is well-absorbed and non-constipating, and it has not caused me any heartburn or stomach aches. The results were immediate, particularly in reducing hair loss. It's important to take it with a source of vitamin C, like orange juice, for optimal absorption.
Knee Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Iron treatment aids knee recovery
Blood management of staged bilateral total knee arthroplasty in a single hospitalization period.
Most Relevant Research
We focused on the effects of iron treatment as part of a broader strategy for managing blood loss and pain in patients undergoing staged bilateral total knee arthroplasty (TKA) within a single hospital stay. In our study, we compared two groups of patients: one receiving a newly introduced multimodal blood management (MBM) approach that included preoperative oral iron treatment, and a control group that only received standard care.
Our findings were promising. The group treated with the MBM protocol experienced significantly lower rates of blood transfusion—only 9% of patients required one—compared to 32.4% in the control group. This approach not only reduced the need for additional blood transfusions but also led to improvements in postoperative hemoglobin levels and reduced pain and swelling in the knees after surgery.
The results suggest that incorporating iron treatment in a comprehensive management program can effectively help alleviate knee pain and enhance recovery from surgery. Best of all, this was achieved without leading to any significant complications, indicating a safe and economical option for improving outcomes in TKA patients.
Our findings were promising. The group treated with the MBM protocol experienced significantly lower rates of blood transfusion—only 9% of patients required one—compared to 32.4% in the control group. This approach not only reduced the need for additional blood transfusions but also led to improvements in postoperative hemoglobin levels and reduced pain and swelling in the knees after surgery.
The results suggest that incorporating iron treatment in a comprehensive management program can effectively help alleviate knee pain and enhance recovery from surgery. Best of all, this was achieved without leading to any significant complications, indicating a safe and economical option for improving outcomes in TKA patients.
9.5
Repeat purchase for relief
Most Useful Review
It has a distinct iron smell and taste, but it effectively relieves menstrual pain, so this is my fourth repeat purchase! I take just one tablet.
Multiple Sclerosis details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Deferiprone promotes remyelination in MS
Deferiprone promoted remyelination and functional recovery through enhancement of oligodendrogenesis in experimental demyelination animal model.
Most Relevant Research
We explored the effects of deferiprone (DFP), a medication known for its ability to chelate iron, on remyelination in a model of multiple sclerosis (MS). Focal demyelination was induced in the optic nerve of mice, and DFP was administered starting a week later to see if it could boost myelin repair.
Our observations revealed that DFP does more than just manage iron levels; it appears to significantly enhance the process of remyelination. We noted a decrease in the g-ratio and an increase in myelin thickness, hints that DFP is promoting the regeneration of myelin sheaths that protect nerve fibers. Furthermore, DFP also encouraged the growth of oligodendrocytes, which are crucial for myelin production, while reducing gliosis, an inflammatory response that can impede recovery.
The outcomes were impressive not just at a cellular level but also functionally. Mice treated with DFP showed notable recovery in their motor and sensory functions through various tests. Although we are still unraveling the precise mechanisms behind these improvements, our findings suggest that with further research, DFP could be a promising candidate for MS treatment focused on enhancing remyelination.
Our observations revealed that DFP does more than just manage iron levels; it appears to significantly enhance the process of remyelination. We noted a decrease in the g-ratio and an increase in myelin thickness, hints that DFP is promoting the regeneration of myelin sheaths that protect nerve fibers. Furthermore, DFP also encouraged the growth of oligodendrocytes, which are crucial for myelin production, while reducing gliosis, an inflammatory response that can impede recovery.
The outcomes were impressive not just at a cellular level but also functionally. Mice treated with DFP showed notable recovery in their motor and sensory functions through various tests. Although we are still unraveling the precise mechanisms behind these improvements, our findings suggest that with further research, DFP could be a promising candidate for MS treatment focused on enhancing remyelination.
9.5
Iron levels stable
Most Useful Review
Works remarkably well! As a vegetarian, I've always been aware of concerns regarding insufficient iron intake. I take these supplements diligently to prevent any issues. After multiple health checks, my iron levels have consistently been fine, and I've not encountered any side effects from these pills.
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.6
8
Iron improves sleep apnea symptoms
Intravenous iron therapy improves the hypercapnic ventilatory response and sleep disordered breathing in chronic heart failure.
Most Relevant Research
We conducted a study to discover how intravenous iron therapy impacts sleep apnea in patients suffering from heart failure, anemia, and iron deficiency. Patients were randomly assigned to receive either ferric carboxymaltose or a placebo to assess changes in their sleep and respiratory function after treatment.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
8.8
Enhanced cognitive function
Most Useful Review
I bought this iron for my daughter, who struggled with lethargy and sleepiness. Along with iron, I also provided vitamin C, folic acid, zinc, and selenium. Now, she feels much better and her iron levels are normal. Beyond normalising her iron, we've seen improvements in her cognitive functions; she's now more alert, diligent, and has a better mood, along with a greater desire to engage in activities rather than lounging in bed.
Hair Loss details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Regaining hair slowly
Most Useful Review
Excellent!!! I believe this is good stuff! Over the past few years, I experienced drastic hair loss, losing about three-quarters of my hair, which my doctors attributed to childbirth. Now, my hormone levels are normal. I began taking various supplements, and after a few months, I observe my eyelashes and leg hairs returning, indicating that my head hair might be growing back too! I'm loving this low-dose iron as it's gentle!
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 18 Reviews
8.5
8
Iron treatment's effects on campylobacteriosis
Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine Infection Model.
Most Relevant Research
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
9.5
Increased energy levels
Most Useful Review
Excellent! I recommend it to active girls! Initially, I took 36 units (NOW Foods Iron Double Strength) as two pieces a day, but here the dosage is 18 units, so I now take four. I can't imagine life without this supplement. My sports and dance routine was exhausting, leaving me depleted. After starting NOW Foods Iron, I felt revitalised and strong again. I truly recommend it!
Frozen Shoulder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
7.8
Reduced numbness
Most Useful Review
Capsules have a strong smell when opened, but I find them effective. I've noticed less freezing and the numbness in my little fingers has disappeared. There were no side effects for me, and the capsules are easy to swallow. Overall, it's a good economical choice.
Leg Cramps details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 11 Reviews
8.5
7
Iron treatment improves leg cramps
Iron deficiency associates with deterioration in several symptoms independently from hemoglobin level among chronic hemodialysis patients.
Most Relevant Research
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.
Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.
The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.
The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
8.3
Effective treatment
Most Useful Review
Effective for the leg chirp syndrome, also known as Restless Leg Syndrome, which I've experienced since junior high. Recently, the symptoms intensified, and after consulting my doctor, I was prescribed legumenite. Being iron-conscious, I decided to try this alternative. Having taken it for about a month now, I've not experienced any symptoms nor do I feel dependent on medication! Occasionally, I feel dizzy, but it appears to have sufficiently helped my legs to rest.
Liver Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 6 Reviews
8.5
9
Rubiadin reduces liver iron overload
Rubiadin Mediates the Upregulation of Hepatic Hepcidin and Alleviates Iron Overload via BMP6/SMAD1/5/9-Signaling Pathway.
Most Relevant Research
We explored the effects of rubiadin, a beneficial compound derived from a Chinese herb, on iron metabolism and its implications for liver disease. Recognizing the challenges posed by iron overload diseases, we aimed to discover a safe approach to manage excessive iron accumulation in the body. Through experiments involving various analyses, we observed that rubiadin significantly downregulated proteins that are typically elevated in conditions of high iron, such as transferrin receptor 1 and ferroportin 1.
Furthermore, when we administered rubiadin to mice with iron overload, it resulted in decreased serum and duodenal iron levels and an increase in hepcidin mRNA expression in the liver. This suggests that rubiadin may not only help the body regulate iron better but might also protect against the harmful effects of excess iron.
Our research also delved into the mechanisms behind these effects. We found that rubiadin-induced hepcidin expression was mediated through a specific signaling pathway involving bone morphogenetic protein 6 (BMP6) and SMAD proteins. The ability of rubiadin to enhance hepcidin levels points toward a promising natural strategy for tackling iron overload in liver diseases and could have broader implications for treating related conditions.
Furthermore, when we administered rubiadin to mice with iron overload, it resulted in decreased serum and duodenal iron levels and an increase in hepcidin mRNA expression in the liver. This suggests that rubiadin may not only help the body regulate iron better but might also protect against the harmful effects of excess iron.
Our research also delved into the mechanisms behind these effects. We found that rubiadin-induced hepcidin expression was mediated through a specific signaling pathway involving bone morphogenetic protein 6 (BMP6) and SMAD proteins. The ability of rubiadin to enhance hepcidin levels points toward a promising natural strategy for tackling iron overload in liver diseases and could have broader implications for treating related conditions.
8.8
Improved absorption
Most Useful Review
The iron in this preparation is bisglycinate, which does not cause the usual side effects of iron supplements such as constipation, diarrhoea, or that unpleasant rusty nail sensation affecting the liver. It can even be taken by pregnant and lactating women. The absorption is significantly higher than that of gluconate, helping prevent iron deficiency anaemia and support ferritin levels effectively.
Osteoporosis details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Cardamonin aids in osteoporosis treatment
Cardamonin attenuates iron overload-induced osteoblast oxidative stress through the HIF-1α/ROS pathway.
Most Relevant Research
We investigated how excess iron in the body affects osteoporosis and how a compound called Cardamonin could help combat this issue. The study involved creating a mouse model with iron overload and assessing the severity of osteoporosis using advanced imaging and staining techniques.
We focused on understanding the cellular effects of high iron levels on osteoblasts, the cells responsible for bone formation. We discovered that iron overload triggers oxidative stress in these cells, which can impede their function and lead to weaker bones. Our findings showed that Cardamonin can mitigate these adverse effects by reducing the buildup of reactive oxygen species (ROS) and promoting healthier bone formation.
Ultimately, we found that by targeting specific pathways related to oxidative stress, Cardamonin offers a promising therapeutic option for addressing osteoporosis exacerbated by iron overload. This research highlights the importance of maintaining proper iron balance for bone health.
We focused on understanding the cellular effects of high iron levels on osteoblasts, the cells responsible for bone formation. We discovered that iron overload triggers oxidative stress in these cells, which can impede their function and lead to weaker bones. Our findings showed that Cardamonin can mitigate these adverse effects by reducing the buildup of reactive oxygen species (ROS) and promoting healthier bone formation.
Ultimately, we found that by targeting specific pathways related to oxidative stress, Cardamonin offers a promising therapeutic option for addressing osteoporosis exacerbated by iron overload. This research highlights the importance of maintaining proper iron balance for bone health.
8.8
Optimises bone health
Most Useful Review
The product is well packaged and cost-effective. It aids in optimising bone health and electrolyte balance while helping to reduce osteoporosis.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
8.8
Calmed tingling sensation
Most Useful Review
I purchased this to alleviate the tingling sensation in my feet while sleeping. After beginning to take it, the issue subsided within just a few days!
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
8.3
Effective without discomfort
Most Useful Review
This iron supplement has effectively raised my ferritin levels within 10 days without causing bloating, stomach pain, or other typical side effects associated with iron. I took it with lunch, and it has proven to be a reliable option that I will continue to use.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.4
7
Iron's Impact on Pregnancy Mental Health
Associations between iron status and psychosocial wellbeing among pregnant women in Cape Coast, Ghana: a longitudinal study.
Most Relevant Research
We set out to explore the connection between iron levels and mental health in pregnant women, focusing on how iron treatment may influence depressive symptoms. Our study recruited participants in their first trimester and followed them through their second and third trimesters, assessing their iron status and psychosocial wellbeing along the way.
Findings revealed that improvements in ferritin levels during the first and second trimesters were associated with fewer depressive symptoms and a better overall quality of life. This suggests that boosting iron levels in early pregnancy could potentially benefit mental health. Moreover, we discovered that increases in hemoglobin were linked to reduced anxiety, particularly feelings of fear, highlighting another positive aspect of improved iron status.
However, the results were more mixed in the later stages of pregnancy. While improvements in transferrin saturation from the second to the third trimester were connected to greater anxiety and a decline in quality of life, the initial positive effects underline the importance of monitoring and managing iron levels throughout pregnancy.
Overall, our findings hint at a beneficial relationship between iron status and psychosocial wellbeing, particularly in early pregnancy. However, more extensive studies are needed to confirm these promising results and better understand the nuances of this connection.
Findings revealed that improvements in ferritin levels during the first and second trimesters were associated with fewer depressive symptoms and a better overall quality of life. This suggests that boosting iron levels in early pregnancy could potentially benefit mental health. Moreover, we discovered that increases in hemoglobin were linked to reduced anxiety, particularly feelings of fear, highlighting another positive aspect of improved iron status.
However, the results were more mixed in the later stages of pregnancy. While improvements in transferrin saturation from the second to the third trimester were connected to greater anxiety and a decline in quality of life, the initial positive effects underline the importance of monitoring and managing iron levels throughout pregnancy.
Overall, our findings hint at a beneficial relationship between iron status and psychosocial wellbeing, particularly in early pregnancy. However, more extensive studies are needed to confirm these promising results and better understand the nuances of this connection.
9.5
Depression relief
Most Useful Review
This product helped with my evening depression. I often felt unwell in the evenings, potentially due to iron deficiency, which led me to purchase it. After starting, my evening depression subsided and I began waking up feeling better. Now I can move through the day without fluctuations. I’d like to increase the dosage gradually, possibly trying 36mg in the future.
Hypothyroidism details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
9.5
Iron levels increased
Most Useful Review
Good results! I enjoyed this medication! Over two months with AIT and hypothyroidism, my iron levels rose from 9 to 15. It did not upset my stomach or cause any pain.
Vertigo details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Iron treatment alleviates vertigo symptoms
Symptom panorama in upper secondary school students and symptoms related to iron deficiency. Screening with laboratory tests, questionnaire and interventional treatment with iron.
Most Relevant Research
Our study aimed to understand how iron deficiency impacts students' experiences, particularly focusing on symptoms like vertigo and dizziness. We set out to identify undiagnosed iron deficiency among first-grade students at an upper secondary school and evaluated changes in their symptoms and lab results after three months of iron supplementation.
Through our research, we found that 12% of the students had iron deficiency, and 61% exhibited some abnormal test results related to iron levels. Notably, we observed that symptoms of vertigo and dizziness were significantly more common in those with iron deficiency. After the students received iron supplementation, we recorded notable improvements: iron levels increased, transferrin levels decreased, and importantly, there was a marked reduction in symptoms, including vertigo, irritability, and depressive feelings.
Our findings convincingly highlight that iron supplementation can be beneficial in alleviating certain symptoms, specifically vertigo and dizziness, among students struggling with iron deficiency. This connection opens doors to addressing quality of life issues tied to iron levels among young individuals.
Through our research, we found that 12% of the students had iron deficiency, and 61% exhibited some abnormal test results related to iron levels. Notably, we observed that symptoms of vertigo and dizziness were significantly more common in those with iron deficiency. After the students received iron supplementation, we recorded notable improvements: iron levels increased, transferrin levels decreased, and importantly, there was a marked reduction in symptoms, including vertigo, irritability, and depressive feelings.
Our findings convincingly highlight that iron supplementation can be beneficial in alleviating certain symptoms, specifically vertigo and dizziness, among students struggling with iron deficiency. This connection opens doors to addressing quality of life issues tied to iron levels among young individuals.
9.5
Virtigo nearly resolved
Most Useful Review
I take three tablets daily and have done so comfortably for about six months, despite some concerns over the ingredients. I haven't had a medical check-up, but the severe vertigo I experienced has almost disappeared since I started the treatment, which has alleviated my daily frustrations. I suspect that my issues may be due to a lack of iron. Additionally, I take an extra Miyairi-san alongside my biotin therapy to tackle constipation fears.
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Good
Based on 9 Reviews
8.3
8
Iron treatment’s impact on bloating
Sucrosomial Iron Supplementation in Anemic Patients with Celiac Disease Not Tolerating Oral Ferrous Sulfate: A Prospective Study.
Most Relevant Research
We explored how iron supplementation impacts patients with celiac disease who suffer from iron deficiency anemia, particularly focusing on those unable to tolerate traditional iron sulfate. In this study, patients were divided into two groups: one receiving a new formulation called sucrosomial iron and the other taking iron sulfate.
After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.
This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.
This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
9.5
No bloating issues
Most Useful Review
The best iron tablet I've tried so far. It's easy to swallow, and I have no concerns about bloating or constipation, which I found some other brands can cause. I read the other reviews and I'm glad I trusted their recommendations.
Ear Infection details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.3
7
Iron deficiency links to ear infections
The association of iron deficiency anemia on chronic suppurative otitis media in children: A case-control study.
Most Relevant Research
We explored how iron deficiency anemia (IDA) may be linked to chronic suppurative otitis media (CSOM), a common ear infection affecting children. Our study involved children diagnosed with CSOM, who were compared to those with normal ear health. We examined various blood markers including hemoglobin levels and iron status to better understand the connection.
The findings revealed that children with CSOM had significantly lower iron levels and higher rates of anemia compared to those in the control group. Notably, 31% of the CSOM group exhibited IDA, while only 12% of the control group did. This suggests a notable association between IDA and the occurrence of ear infections in children.
Ultimately, while the study highlights the prevalence of IDA among children suffering from CSOM, it points toward the importance of monitoring iron levels in these patients to potentially reduce the incidence of ear infections.
The findings revealed that children with CSOM had significantly lower iron levels and higher rates of anemia compared to those in the control group. Notably, 31% of the CSOM group exhibited IDA, while only 12% of the control group did. This suggests a notable association between IDA and the occurrence of ear infections in children.
Ultimately, while the study highlights the prevalence of IDA among children suffering from CSOM, it points toward the importance of monitoring iron levels in these patients to potentially reduce the incidence of ear infections.
8.8
Strengthened immune response
Most Useful Review
Though I have only taken the iron supplement for a brief period, I already feel a strengthening of my immune system. After catching a viral infection, my symptoms were minimal and resolved quickly. Doubling my daily iron dosage helped me maintain my energy levels at the gym without feeling weak afterward. I don't know if it's all related, but I am satisfied with my progress.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
9.5
No allergic reactions
Most Useful Review
Excellent! I've always had a shortage of iron and tried numerous medications from pharmacies, but I was allergic to everything, resulting in a rash on my hands. I ordered this one, and to my surprise, I finished a jar with no side effects! Thank you! I'm eager for it to be back in stock.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
USERS' SCORE
Good
Based on 3 Reviews
8.2
4
Iron Supplementation and Gut Microbiota
The Impact of Low-Level Iron Supplements on the Faecal Microbiota of Irritable Bowel Syndrome and Healthy Donors Using In Vitro Batch Cultures.
Most Relevant Research
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
9.5
More energy
Most Useful Review
Very good! I feel the difference when I take the iron. I have more energy and no bowel problems.
Menopause details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Iron treatment in menopause study
Deferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation.
Most Relevant Research
We investigated how iron treatment affects iron levels and blood production in rats that underwent ovariectomy, a procedure mimicking menopause. By using Deferasirox, a medication often prescribed for iron overload conditions, we aimed to understand its role in managing iron levels and supporting blood health in this context.
Our study involved sixty-four female Wistar rats divided into several groups. After undergoing surgery to simulate menopause, we induced iron accumulation in them. We then treated some groups with Deferasirox at varying doses and looked into its effects on their health.
We observed that the treatment with Deferasirox led to improved conditions in several key areas. There were noticeable positive changes in the uterine tissue, an increase in white blood cells, and a decrease in harmful iron levels. Moreover, the treatment increased the body’s antioxidant capacity, helping fight oxidative stress commonly seen in menopausal conditions.
Deferasirox also had beneficial effects on bone health and the overall functioning of blood-producing cells. Additionally, it influenced gene expressions related to iron metabolism and blood production. Overall, we found that Deferasirox plays an important role in managing iron and enhancing blood health in rats experiencing conditions similar to menopause.
Our study involved sixty-four female Wistar rats divided into several groups. After undergoing surgery to simulate menopause, we induced iron accumulation in them. We then treated some groups with Deferasirox at varying doses and looked into its effects on their health.
We observed that the treatment with Deferasirox led to improved conditions in several key areas. There were noticeable positive changes in the uterine tissue, an increase in white blood cells, and a decrease in harmful iron levels. Moreover, the treatment increased the body’s antioxidant capacity, helping fight oxidative stress commonly seen in menopausal conditions.
Deferasirox also had beneficial effects on bone health and the overall functioning of blood-producing cells. Additionally, it influenced gene expressions related to iron metabolism and blood production. Overall, we found that Deferasirox plays an important role in managing iron and enhancing blood health in rats experiencing conditions similar to menopause.
8.8
Improved overall health
Most Useful Review
Previously, I occasionally took various iron products, but as I entered menopause, I began to feel dizzy and lightheaded. After reading Dr. Fujikawa's book, I discovered that this chelated iron is the most efficient for absorption, so I purchased it. I want to continue because iron is vital for health, and improving my anaemia alleviates numerous symptoms throughout my body. I choose the small 18ml size for easy consumption while avoiding over-intake.
Headache details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.1
9.5
No side effects
Most Useful Review
I've discovered the quality of the iron in this product is fantastic. I take it daily as it’s rich in essential minerals. I’ve experienced no side effects, and within three days, I noticed relief from my headaches and a reduction in hair loss. I feel more energetic!
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 33 Reviews
7.8
8.8
Eased menstrual pain
Most Useful Review
Since I began this iron supplement, symptoms of anaemia and menstrual pain have improved. My menstruation feels lighter, and I'm able to work without discomfort. However, without proper iron intake, constipation can occur. This iron remedy seems to be a good alternative to others I've tried.
Diarrhea details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.6
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Most Relevant Research
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
6.8
Slight diarrhoea
Most Useful Review
I've noticed my stomach feels slightly looser after taking these iron supplements. While I don't feel nauseous like with hospital-prescribed iron, I do have some diarrhoea. I’m uncertain if the iron is the cause since I've taken other supplements too, but I will try taking one capsule daily to see if it helps.
Nausea details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.3
9
FCH reduces nausea in IDA treatment
A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH.
Most Relevant Research
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
7
No side effects reported
Most Useful Review
No, oh, oh! Bisglycinate is the best type of iron, with the lightest absorption in the stomach. I experienced no nausea or liver tenderness whatsoever. I wish they had included folic acid and vitamin B12 to enhance its benefits.
