Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin D-3 (as Cholecalciferol)
25 mcg (1,000 IU)
125%
Calcium (from Aquamin® TG Seaweed Derived Minerals and Calcium Citrate)
400 mg
31%
Magnesium (from Magnesium Oxide, Magnesium Glycinate, Magnesium Taurinate, Magnesium Citrate and Aquamin® TG Seaweed Derived Minerals)
800 mg
190%
Zinc (from L-OptiZinc® Monomethionine)
15 mg
136%
The product is found useful for the following medical conditions
Leg Cramps details
SCIENTIFIC SCORE
Questionable
Based on 25 Researches
5.2
USERS' SCORE
Excellent
Based on 46 Reviews
9
9
Magnesium oxide treats leg cramps
A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Most Relevant Research
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
8.8
Relieves leg cramps
Most Useful Review
Calcium and magnesium are essential minerals that ensure the smooth functioning of nearly all body systems. They support the health of the musculoskeletal, nervous, and cardiovascular systems. This supplement improves sleep quality, alleviates cramps, relaxes me, and helps reduce nervous tension. I find it best to take before bed. It's an excellent choice, and the price reflects the quality. I highly recommend it.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 17 Reviews
8.8
8
Zinc’s effects on colds
Zinc for prevention and treatment of the common cold: Summary of a Cochrane review.
Most Relevant Research
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
9.5
Cold sensitivity reduced
Most Useful Review
Initially, I was troubled by tooth sensitivity, particularly to cold food. However, after commencing this vitamin course, I saw a marked reduction in sensitivity after about 10 days. I'm pleased to report that it has now completely resolved.
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Good
Based on 23 Reviews
8.8
8
Magnesium alleviates primary dysmenorrhea
Effectiveness of magnesium pidolate in the prophylactic treatment of primary dysmenorrhea.
Most Relevant Research
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
10
PMS relief
Most Useful Review
I deliberated over my magnesium choice and opted for this ratio, which I don't regret. Ladies, listen up! My painful periods and pre-menstrual irritation vanished with a course of magnesium and calcium. Initially, I faced gastrointestinal issues, but they resolved as my body adjusted. My nervous system calmed down remarkably, improving my sleep, and I no longer experience PMS or menstrual pain. I highly recommend this optimal combination of magnesium and calcium!
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 11 Reviews
8.7
8
Zinc may alleviate anxiety symptoms
A systematic review of the association between zinc and anxiety.
Most Relevant Research
We explored the connection between zinc intake and anxiety in adults through a systematic review of nine original studies. Two of these studies looked at how zinc consumption impacts anxiety, while the other seven focused on the relationship between serum zinc levels and anxiety symptoms. Our analysis included studies published in English within peer-reviewed journals, ensuring a solid foundation for understanding this potential link.
What we discovered was quite illuminating. The data indicated that individuals experiencing anxiety often had lower levels of zinc in their serum compared to those who did not suffer from anxiety. Additionally, we observed an inverse association between zinc intake and anxiety levels. This suggests that higher consumption of zinc may contribute to reduced anxiety symptoms.
In conclusion, the evidence points towards zinc playing a positive role in treating anxiety, although we acknowledge some limitations in the available studies. This means zinc supplementation could be a beneficial strategy for those looking to manage their anxiety, but more research is needed to confirm these findings and understand the underlying mechanisms better.
What we discovered was quite illuminating. The data indicated that individuals experiencing anxiety often had lower levels of zinc in their serum compared to those who did not suffer from anxiety. Additionally, we observed an inverse association between zinc intake and anxiety levels. This suggests that higher consumption of zinc may contribute to reduced anxiety symptoms.
In conclusion, the evidence points towards zinc playing a positive role in treating anxiety, although we acknowledge some limitations in the available studies. This means zinc supplementation could be a beneficial strategy for those looking to manage their anxiety, but more research is needed to confirm these findings and understand the underlying mechanisms better.
9.5
Anxiety support
Most Useful Review
Absolutely fantastic! I spent hours searching for the best magnesium, and I found it! The combination of magnesium, calcium, and zinc works perfectly, especially with B complex. It's effectively addressed my anxiety and supported my nervous system! Additionally, my workouts have improved distinctly, and I'm eager for it to be back in stock!
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.7
8
Magnesium protects against bone erosion
Serum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study.
Most Relevant Research
We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
9.5
Reduces joint swelling
Most Useful Review
This product was recommended to me for arthritis pain, particularly in my knees. I've been using it for over 12 years, and it effectively decreases swelling and pain caused by arthritis. If I run out, the pain returns swiftly. I always ensure I have it on hand, as it significantly helps my condition.
Athlete’s Foot details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
USERS' SCORE
Good
Based on 6 Reviews
8.7
9.5
Zinc aids athlete's foot treatment
Efficacy of undecylenic acid-zinc undecylenate powder in culture positive tinea pedis.
Most Relevant Research
We explored the effectiveness of a powder containing 2% undecylenic acid and 20% zinc undecylenate for treating athlete's foot, also known as tinea pedis. In a double-blind study, 151 participants were assigned to apply either the active powder or a placebo twice daily for four weeks. The results were telling.
From the 85 patients with confirmed fungal infections, a remarkable 88% of those using the active powder had negative cultures after the treatment, compared to only 17% in the placebo group. Additionally, 80% of those on the active treatment were found to be free of fungus in KOH skin scrapings after four weeks, while only 49% of placebo users achieved this. Furthermore, we observed significant improvement in symptoms like itching, burning, erythema, and scaling, with no side effects reported.
Overall, our findings indicate that the combination of undecylenic acid and zinc may offer a robust solution for individuals suffering from athlete's foot, effectively reducing fungal presence and alleviating uncomfortable symptoms. However, it is important to note that while zinc played a role in this combination treatment, we cannot fully assess its isolated effect on its own without further studies.
From the 85 patients with confirmed fungal infections, a remarkable 88% of those using the active powder had negative cultures after the treatment, compared to only 17% in the placebo group. Additionally, 80% of those on the active treatment were found to be free of fungus in KOH skin scrapings after four weeks, while only 49% of placebo users achieved this. Furthermore, we observed significant improvement in symptoms like itching, burning, erythema, and scaling, with no side effects reported.
Overall, our findings indicate that the combination of undecylenic acid and zinc may offer a robust solution for individuals suffering from athlete's foot, effectively reducing fungal presence and alleviating uncomfortable symptoms. However, it is important to note that while zinc played a role in this combination treatment, we cannot fully assess its isolated effect on its own without further studies.
9.5
Improves running
Most Useful Review
The doctor recommended this for my teenage athlete for better muscle and heart function. Cramps have disappeared, making running distances easier. I'm pleased with this brand.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.3
USERS' SCORE
Good
Based on 31 Reviews
8.7
7
CMT shows potential for pain relief
The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study.
Most Relevant Research
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
9.5
Pain relief achieved
Most Useful Review
While breastfeeding, I often experienced bone pain. After taking these supplements for two weeks, the pain subsided. Additionally, my nails have become significantly stronger.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
7
Zinc supplementation may benefit CFS
Lower serum zinc in Chronic Fatigue Syndrome (CFS): relationships to immune dysfunctions and relevance for the oxidative stress status in CFS.
Most Relevant Research
We explored the relationship between serum zinc levels and chronic fatigue syndrome (CFS) in a study that compared patients with CFS to normal volunteers. By using an atomic absorption method, we measured serum zinc concentrations and found that those suffering from CFS had significantly lower levels of zinc compared to healthy individuals.
Interestingly, we observed a trend indicating that lower zinc levels correlated with greater CFS severity. Patients also reported a negative correlation between their zinc levels and their subjective experiences of infection. This suggests that zinc plays a role in the immune dysfunction commonly seen in CFS.
Furthermore, we noted that lower serum zinc was associated with higher levels of inflammatory markers and certain defects in the early activation of T cells. Since zinc acts as a potent antioxidant, our findings indicate that CFS is linked to increased oxidative stress in these patients. Given this, it may be beneficial for some CFS patients to consider zinc supplements as part of their treatment approach.
Interestingly, we observed a trend indicating that lower zinc levels correlated with greater CFS severity. Patients also reported a negative correlation between their zinc levels and their subjective experiences of infection. This suggests that zinc plays a role in the immune dysfunction commonly seen in CFS.
Furthermore, we noted that lower serum zinc was associated with higher levels of inflammatory markers and certain defects in the early activation of T cells. Since zinc acts as a potent antioxidant, our findings indicate that CFS is linked to increased oxidative stress in these patients. Given this, it may be beneficial for some CFS patients to consider zinc supplements as part of their treatment approach.
10
Life-changing effects
Most Useful Review
This supplement has truly changed my life; I was overwhelmed by fatigue and struggled to work. The severe symptoms I experienced have thankfully disappeared. What I once thought required hormone treatments was actually resolved by this simple supplement. I can hardly believe the difference it has made.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
Magnesium intake reduces depression risk
Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies.
Most Relevant Research
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
9.5
Calmness restored
Most Useful Review
Magnesium aids with depression! Initially, I opted for this complex due to the zinc, hoping to improve my skin, but I discovered that magnesium has been incredibly beneficial. After just two weeks, I felt remarkably calm amidst my stress and depression. I experienced better sleep, waking less frequently during the night, and my nightmares have vanished. Additionally, my daily bowel movements have improved, especially since my medications usually cause constipation. I take two tablets in the evening, although they are rather large and difficult to swallow.
Hair Loss details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 11 Reviews
8.7
9
Zinc shows promise for hair loss
Symptom Profile of Patients With Post-COVID-19 Conditions and Influencing Factors for Recovery.
Most Relevant Research
We explored how zinc acetate hydrate impacts hair loss for patients experiencing symptoms after COVID-19. In our analysis, we looked at 120 symptomatic outpatients over 12 weeks, observing their recovery patterns and any improvements in their symptoms. The focus was on various lingering effects, including fatigue and hair loss, particularly how zinc could potentially alleviate these issues.
Our findings highlighted significant improvements in hair loss for those treated with zinc acetate hydrate at multiple checkpoints (4, 8, and 12 weeks) compared to those who did not receive this treatment. The results were statistically significant and suggested that zinc could be a useful option for those struggling with hair loss post-COVID-19.
Additionally, we noted improvements in fatigue among those receiving zinc, although this was not as pronounced at all time intervals. As a whole, our study emphasized zinc's beneficial effects, particularly for hair loss, providing promising insights for anyone dealing with these challenging post-viral symptoms.
Our findings highlighted significant improvements in hair loss for those treated with zinc acetate hydrate at multiple checkpoints (4, 8, and 12 weeks) compared to those who did not receive this treatment. The results were statistically significant and suggested that zinc could be a useful option for those struggling with hair loss post-COVID-19.
Additionally, we noted improvements in fatigue among those receiving zinc, although this was not as pronounced at all time intervals. As a whole, our study emphasized zinc's beneficial effects, particularly for hair loss, providing promising insights for anyone dealing with these challenging post-viral symptoms.
9
Improved hair loss
Most Useful Review
Complex for hair, nails, bones and the nervous system. Calcium and magnesium support the nervous and skeletal systems. I ordered this set on my doctor's recommendation due to post-pregnancy leg cramps, hair loss, and constant nervousness. Calcium serves as a building block for hair, and its deficiency can lead to various health issues, including deteriorating hair condition. Adequate vitamin levels are needed for calcium absorption. Laboratory studies show magnesium depletion in hair for those with nervous system issues and chronic stress. After taking the complex, I noticed hair loss has decreased, my nerves have calmed, and leg cramps are subsiding. It's a non-GMO, kosher product!
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.1
USERS' SCORE
Good
Based on 17 Reviews
8.6
9
Magnesium shows promise for RA treatment
Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways.
Most Relevant Research
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
10
Improved sleep quality
Most Useful Review
I appreciate being able to take magnesium and calcium together, particularly with higher magnesium content. Originally, I took it to treat my atopic dermatitis, which is now completely healed, so I now only take it with other vitamins when particularly fatigued. The refreshing effect is evident the next morning. I am careful not to over-supplement to avoid straining my liver.
Chest Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Magnesium improves chest pain outcomes
Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease.
Most Relevant Research
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
8.8
Vitamin improvement
Most Useful Review
The quality is excellent, similar to other Know Foods products. The dosage of calcium and magnesium is adequate. I experienced cramps and bone pain due to a vitamin deficiency, but noticeable improvements were evident after the course. I highly recommend this to everyone.
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Soothes dry throats
Most Useful Review
USDA Organic helps alleviate occasional coughs due to irritated or dry throats. It includes Vitamin C, Honey, and Elderberry and comes in a convenient, sippy-safe syringe with 24 servings. This liquid dietary supplement is for children aged 1-12 and is certified organic by Quality Assurance International (QAI). The contents are certified by NSF® and are Non-GMO. Organic Children's Cough Syrup is an herbal supplement designed specifically for children to soothe dry throats and relieve occasional coughs.
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Zinc cream alleviates cold sores
A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine.
Most Relevant Research
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9.5
Cramps gone
Most Useful Review
I take this product for leg cramps and cold prevention during winter. The calve cramps have ceased entirely since I started using it.
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
Most Relevant Research
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
8.8
Increased resistance
Most Useful Review
I've been taking this vitamin for a month and have already noticed a difference. It’s a fantastic supplement for the family; it has certainly boosted my energy levels and mood. Additionally, it helps my resistance to colds, and I feel it positively affects my skin.
Diabetes details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.6
9
Zinc alleviates diabetic muscle atrophy
Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39.
Most Relevant Research
Our investigation aimed to understand how zinc affects muscle atrophy in diabetes, a serious complication that leads to muscle loss. Using diabetes-induced mice, we treated them with zinc sulfate for six weeks and observed notable improvements in their muscle condition.
We conducted various analyses to evaluate the impact of zinc on autophagy—the process that helps manage muscle mass. The results were promising; zinc appeared to enhance muscle recovery by regulating specific molecular pathways connected to muscle health.
Additionally, our in vitro studies with diabetic muscle cells revealed similar results, with zinc supplementation proving beneficial in reducing excessive autophagy. Overall, this suggests that incorporating zinc into treatment plans could be a promising approach to counteract muscle deterioration in diabetic patients.
We conducted various analyses to evaluate the impact of zinc on autophagy—the process that helps manage muscle mass. The results were promising; zinc appeared to enhance muscle recovery by regulating specific molecular pathways connected to muscle health.
Additionally, our in vitro studies with diabetic muscle cells revealed similar results, with zinc supplementation proving beneficial in reducing excessive autophagy. Overall, this suggests that incorporating zinc into treatment plans could be a promising approach to counteract muscle deterioration in diabetic patients.
9.5
Normalises blood sugar
Most Useful Review
I regularly purchase these vitamins for my son, who has type 1 diabetes mellitus. Following our endocrinologist’s advice, these supplements help normalise bodily functions, reduce blood sugar levels, enhance limb sensitivity, and improve overall alertness.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
Most Relevant Research
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
9.5
Improves sleep quality
Most Useful Review
We had issues with leg cramps, but since starting this supplement, they have completely disappeared, and we've also enjoyed healthier sleep.
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 35 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.6
9
Magnesium's role in osteoporosis therapy
Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism.
Most Relevant Research
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
10
Highly effective
Most Useful Review
This supplement is very effective for treating osteoporosis.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Rash disappeared
Most Useful Review
These vitamins are excellent! I started taking them to treat my sun allergies on my hands and improve my sleep. To my amazement, after just three days, the rash on my hands vanished! I struggled with this rash for two years with no success, but calcium has worked wonders. I now fall asleep quicker, but I did experience a pronounced laxative effect, so I reduced my intake to one tablet at night. Despite this, the positive effects remain. Overall, I'm very satisfied!
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 42 Reviews
8.6
9
Zinc protects heart function in OSA
Zinc Is Indispensable in Exercise-Induced Cardioprotection against Intermittent Hypoxia-Induced Left Ventricular Function Impairment in Rats.
Most Relevant Research
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
9.5
Relaxation improved
Most Useful Review
I recommend this product, which I bought at a promotional price. Although the composition did not initially impress me, my hamster took to it! I take 1 tablet in the evening, sometimes 2, and in the morning, I have malate or glycinate. While I take high doses of Vitamin D daily, I find zinc a nice addition. This magnesium complex truly aids my relaxation and helps me sleep well, unlike other chelated compounds I've tried. I found myself so satisfied that I bought another tub. I don't take them during the day, as they make me sleepy. Note that I experience slight relaxation of my stool with 3 capsules, which I mix with other magnesium types.
Toothache details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 6 Reviews
8.6
8
Calcium treatment shows comparable results
Eighteen-month clinical and radiographic evaluation of two root canal-filling materials in primary teeth with pulp necrosis secondary to trauma.
Most Relevant Research
We compared two root canal-filling materials used in treating primary teeth with pulp necrosis caused by trauma. Our main focus was on the effectiveness of a calcium hydroxide-based paste versus traditional zinc oxide and eugenol cement, specifically looking at clinical and radiographic outcomes after 18 months.
In our study involving 26 children, we found that both materials demonstrated similar success rates. Clinical success included factors like the absence of pain and tooth mobility, while radiographic success was determined by the healing of tooth roots. Our results indicated that both calcium treatment and zinc oxide function well for the root canal filling in children suffering from pulp necrosis, making them suitable options.
Overall, our findings suggest that whether we use calcium hydroxide or zinc oxide, parents and dentists can expect effective outcomes when treating dental trauma in young children. Thus, both materials are viable choices for addressing toothache related to pulp issues in primary teeth.
In our study involving 26 children, we found that both materials demonstrated similar success rates. Clinical success included factors like the absence of pain and tooth mobility, while radiographic success was determined by the healing of tooth roots. Our results indicated that both calcium treatment and zinc oxide function well for the root canal filling in children suffering from pulp necrosis, making them suitable options.
Overall, our findings suggest that whether we use calcium hydroxide or zinc oxide, parents and dentists can expect effective outcomes when treating dental trauma in young children. Thus, both materials are viable choices for addressing toothache related to pulp issues in primary teeth.
9.5
Improved well-being
Most Useful Review
Calcium and magnesium in one tablet is truly a blessing. It relieved my toothache, thickened my hair, strengthened my nails, and restored my overall well-being. Most importantly, I now enjoy a good night’s sleep once more.
Bloating details
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.1
USERS' SCORE
Good
Based on 6 Reviews
8.5
8
Magnesium alleviates menstrual bloating
Magnesium supplementation alleviates premenstrual symptoms of fluid retention.
Most Relevant Research
We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
9.5
Bloating disappeared
Most Useful Review
For starters, my stool became regular 🙈 and the bloating almost disappeared. Sleep has improved!
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.2
USERS' SCORE
Good
Based on 4 Reviews
8.5
8
Magnesium's impact on heart health
The Role of Dietary Magnesium in Cardiovascular Disease.
Most Relevant Research
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
8.8
Effective prevention
Most Useful Review
Be healthy! It was recommended to take this complex for the prevention of cardiovascular disease. I strongly recommend this product and hope my review assists you in making a choice. I would appreciate any feedback. Thank you in advance for your engagement!
Frozen Shoulder details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 4 Reviews
8.5
9
Calcium treatment shows promise
Treatment for frozen shoulder combined with calcific tendinitis of the supraspinatus.
Most Relevant Research
We explored the effects of calcium deposition in the rotator cuff tendons on frozen shoulder, particularly in cases where calcific tendinitis was present. The study involved 32 patients who underwent a specialized procedure combining arthroscopic brisement of the shoulder joint with multiple punctures at the calcific site. This innovative approach aimed to alleviate the pain and restore mobility linked to frozen shoulder.
After following up with the patients for two years, we observed that 30 out of 32 patients reported satisfactory outcomes. While five individuals still showed some postoperative calcium deposits, many experienced significant improvements in their range of motion and relief from pain. This suggests that combining treatment methods can enhance recovery, although we recognize that the isolated effect of calcium treatment alone remains unclear.
Overall, this study contributes valuable insight into managing frozen shoulder, especially when associated with calcific tendinitis, even if it doesn't fully isolate the impact of calcium treatment.
After following up with the patients for two years, we observed that 30 out of 32 patients reported satisfactory outcomes. While five individuals still showed some postoperative calcium deposits, many experienced significant improvements in their range of motion and relief from pain. This suggests that combining treatment methods can enhance recovery, although we recognize that the isolated effect of calcium treatment alone remains unclear.
Overall, this study contributes valuable insight into managing frozen shoulder, especially when associated with calcific tendinitis, even if it doesn't fully isolate the impact of calcium treatment.
9.5
Significant recovery observed
Most Useful Review
Last winter, my sister fell on an ice rink, sustaining a severe knee contusion and a dislocated shoulder joint. We combined this dietary supplement with D3, bromelain, and turmeric with boswellia. Initially, for two months, there were no results. However, once she began taking this supplement, the doctor noted a remarkable improvement after three weeks, as confirmed by a follow-up. While the entire supplement set contributed, this one also played a role, hence the “5 stars”.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.6
USERS' SCORE
Good
Based on 9 Reviews
8.5
9
Zinc reduces migraine symptoms
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women.
Most Relevant Research
We conducted a randomized, double-blind, placebo-controlled trial to explore how zinc gluconate affects migraine symptoms in women. Sixty participants, with an average age of 35, were given either 15 mg of zinc per day or a placebo for 12 weeks, allowing us to measure the impact on headache frequency, duration, and intensity.
The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.
Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.
In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.
Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.
In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
10
No headaches
Most Useful Review
It worked brilliantly; the headaches are gone, and the experience is delightful without any side effects.
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
USERS' SCORE
Good
Based on 7 Reviews
8.5
9
Zinc enhances vitamin D in menopause
Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial.
Most Relevant Research
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
9.5
Supports menopause health
Most Useful Review
I truly appreciate this supplement! I've been taking it for years due to my osteopenia condition. Its quality and effectiveness are unquestionable. I also take vitamins D and K alongside it and recommend it to all women experiencing menopause.
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.4
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
7.5
Effective for prevention
Most Useful Review
I take these daily as part of my migraine prevention regime. They are large but not difficult to swallow. Since starting them, my migraines have become noticeably lighter. However, when I stopped after six months, my migraines began to worsen again.
Gastritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Good
Based on 2 Reviews
8.4
8
Calcium's role in gastritis therapy
A Dual-Biomineralized Yeast Micro-/Nanorobot with Self-Driving Penetration for Gastritis Therapy and Motility Recovery.
Most Relevant Research
We explored the potential of calcium treatment for alleviating gastritis through innovative yeast micro-/nanorobots. In this study, a self-driving Cur@CaY-robot was devised using a dual biomineralization process to incorporate calcium carbonate. These robots are designed to navigate the harsh gastric environment, effectively delivering curcumin, a natural anti-inflammatory compound.
What we found particularly interesting is how these robots can penetrate deep into thick gastric mucus. This ability not only improves the concentration of curcumin in gastric wall tissues but also releases calcium cations, which seem to play a dual role in both enhancing drug delivery and aiding the recovery of gastric motility in mice suffering from gastritis.
While leveraging the biocompatibility and biodegradability of the yeast-based robots, our findings suggest that calcium can indeed have a notable effect in the context of gastritis treatment. However, it’s important to note that the interplay between calcium and curcumin might complicate our understanding of their individual impacts on gastritis. The study points to promising avenues for future research, emphasizing the need for deeper exploration into how these elements work together.
What we found particularly interesting is how these robots can penetrate deep into thick gastric mucus. This ability not only improves the concentration of curcumin in gastric wall tissues but also releases calcium cations, which seem to play a dual role in both enhancing drug delivery and aiding the recovery of gastric motility in mice suffering from gastritis.
While leveraging the biocompatibility and biodegradability of the yeast-based robots, our findings suggest that calcium can indeed have a notable effect in the context of gastritis treatment. However, it’s important to note that the interplay between calcium and curcumin might complicate our understanding of their individual impacts on gastritis. The study points to promising avenues for future research, emphasizing the need for deeper exploration into how these elements work together.
8
Helps relieve spasms
Most Useful Review
Magnesium gives me energy and appears to soften stool, yet is not recommended for ulcers, gastritis, or high acidity. If you’re unsure which magnesium form to choose, it’s advisable to alternate to prevent dependency; another variant may suit you better. I’ve tried many types, and I can attest that they generally seem effective. When I experience pain during menstruation, I prefer taking magnesium over painkillers, and it’s genuinely helpful as it alleviates spasms.
Kidney Stones details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Magnesium reduces kidney stone risk
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
Most Relevant Research
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
7.5
Good calcium form
Most Useful Review
I purchased this for my parents as it’s a recommended form of calcium. I used it myself as directed by my doctor for oxalates in my kidneys, aiming to dissolve them. This product has been effective in managing my condition.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
8
Legs no longer swollen
Most Useful Review
Excellent quality for the entire family; we have been using it for over a year and I highly recommend it! My legs have stopped feeling fatigued, the night cramps have ceased, and muscle spasms are no longer an issue. It appears that the swelling in my legs has also diminished. Magnesium plays a crucial role in activating around 600 enzymes within the body, aids in hormone storage and production, and is vital for maintaining healthy bones and muscle functions. A deficiency in magnesium can lead to painful cramps, especially during sleep, as well as increased fatigue. Recent research indicates that magnesium supplementation may benefit individuals with restless legs syndrome.
Reflux details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.2
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
Magnesium alginate effectively treats LPR
Magnesium alginate in patients with laryngopharyngeal reflux.
Most Relevant Research
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
9.5
Feel healthier now
Most Useful Review
Above all, I feel much healthier after eating. Thank you so much, my wonderful herb! The quality is undeniable. I started taking this product after meals, and it has been effective. I previously struggled with reflux esophagitis for a long time, but this product has proven reliable. Life can be stressful, but I’m determined not to let it get to me. I aim to maintain a healthy mind and body through various challenges, not solely through exercise, and this product supports that effort.
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 33 Researches
6.9
USERS' SCORE
Good
Based on 5 Reviews
8.2
9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Most Relevant Research
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
9.5
Cramps resolved
Most Useful Review
I ordered this for my mother, who suffered from severe leg cramps. After two weeks of taking these tablets, her cramps disappeared, and we are immensely grateful. We took one tablet in the morning and another in the evening!
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.6
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
Most Relevant Research
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
10
Product effective at night
Most Useful Review
I take this magnesium at night for insomnia, in combination with melatonin. I’ve been sleeping very well since I started!
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
Magnesium boosts colonic activity
Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.
Most Relevant Research
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
9.5
Consistent bowel function
Most Useful Review
I take one magnesium citrate tablet in the morning and one magnesium & calcium tablet after dinner or before bed. They never fail me—there’s no diarrhoea or loose motions. As a result, my bowels are regular every morning, which makes this a necessary addition to my routine.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.1
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
Most Relevant Research
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
9.5
Significant improvement
Most Useful Review
I have shared this link with many friends to assist others! I am new to taking vitamins as I dislike swallowing pills, but these tablets are fantastic! They are not too big, making them easy to take. As a college student under stress, I have had significant acne issues. After a few weeks of taking this, I noticed a remarkable difference. I now occasionally get a pimple, which is normal. Additionally, it has aided in alleviating my anxiety and muscle spasms. I will definitely continue to take them and order from Amazon, as I haven't found a better price for 250 tablets. I highly recommend this to anyone considering purchasing; you won't be disappointed.
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.1
9
Magnesium sulfate alleviates postoperative pain
Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
Most Relevant Research
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
7
Pill difficulty
Most Useful Review
It was challenging to take these large pills, but after finishing the course, I noticed I felt calmer, and my knee pain has stopped.
Urinary Tract Infection details
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.3
USERS' SCORE
Good
Based on 2 Reviews
8.1
9.5
Calcium fosfomycin effective for UTIs
Pharmacokinetic/Pharmacodynamic Analysis of Oral Calcium Fosfomycin: Are Urine Levels Sufficient to Ensure Efficacy for Urinary Tract Infections?
Most Relevant Research
We explored the potential of calcium fosfomycin, a well-known antibiotic, in treating urinary tract infections (UTIs). Our focus was on how effectively it works when taken orally by healthy women. We dove into the drug’s urine concentration levels after administration, noting that about 18% of the drug is excreted through urine. This low level of excretion relates back to its poor oral absorption and reliance on the kidneys to filter it out.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
8.3
Twitching alleviated
Most Useful Review
After experiencing my eye twitching and a racing heart, likely from Covid and stress at age 30, I decided to try magnesium for the first time. I wanted pure glycinate, but it wasn’t available, so I opted for this product due to its reasonable price. It contains various forms of magnesium, with glycinate in second place. I noticed the eye twitching stopped almost immediately. While taking other vitamins, I had to adjust my vitamin D dose, which I took separately and reduced from three to two tablets. The size of the tablets is on the larger side for me, but they have significantly improved my condition, and I’ve had no gastrointestinal problems with this brand.
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 25 Researches
6.9
USERS' SCORE
Good
Based on 20 Reviews
8
9
Effective treatment for chronic constipation
Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial.
Most Relevant Research
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
9.5
Regular soft stools
Most Useful Review
I previously went to the bathroom about twice a week. After starting this, I now have soft stools daily, and I've realised they don't have to be hard.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.7
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.5
8
Magnesium scaffold shows promising results
A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study.
Most Relevant Research
We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
1.3
No results found
Most Useful Review
I have not seen any results from using this product. In my latest blood test, my calcium levels even decreased. Therefore, I plan to stop using it and follow up with another blood test.
Heartburn details
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.5
9
Zinc's role in heartburn relief
Esophageal ulcer related to zinc deficiency following a total gastrectomy.
Most Relevant Research
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.
Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
8.8
Less heartburn
Most Useful Review
This product contains magnesium and calcium, and unlike others, it doesn't have a fishy taste. I also noticed I experienced less heartburn after taking it, which is a definite plus for me.
Nausea details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.6
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.5
8
Magnesium effectively reduces PONV
Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial.
Most Relevant Research
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
10
No nausea experienced
Most Useful Review
An excellent product that is easy to swallow, causing no allergies or nausea. As a breastfeeding mother, I am pleased to report that neither I nor my baby experience any negative reactions to this preparation.
Flu details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.4
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
Most Relevant Research
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9.5
Recovered from flu
Most Useful Review
Magnesium and calcium were taken for my parents to recover from the flu.
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.2
9.5
Zinc oxide combats foodborne pathogens
Active Packaging of Immobilized Zinc Oxide Nanoparticles Controls Campylobacter jejuni in Raw Chicken Meat.
Most Relevant Research
We set out to explore how zinc oxide nanoparticles (ZnO NPs) could help control the bacteria responsible for food poisoning in raw chicken meat. Our approach involved integrating these nanoparticles into packaging materials to see if they could effectively inactivate Campylobacter jejuni, a common and concerning pathogen in poultry.
Through our experiments, we discovered that immobilizing ZnO NPs in functional pads placed under raw chicken could dramatically reduce bacterial counts. In fact, we saw a reduction from about 4 log CFU to an undetectable level within just three days when storing chicken at 4°C. Notably, we monitored zinc levels in the chicken meat, confirming a safe release of zinc without any migration of nanoparticles onto the food. This means that we can help keep raw chicken safe and fresh without compromising its integrity or quality.
Not only did we find that these functional pads inactivated the harmful bacteria, but we also noted a related increase in lactic acid production, which plays a role in further protecting the meat. Our findings open up new avenues for using zinc in food packaging, offering a way to enhance food safety without directly adding chemicals to the food itself. Overall, this study highlights the potential for nanotechnology to play a significant role in managing foodborne pathogens like Campylobacter in poultry products.
Through our experiments, we discovered that immobilizing ZnO NPs in functional pads placed under raw chicken could dramatically reduce bacterial counts. In fact, we saw a reduction from about 4 log CFU to an undetectable level within just three days when storing chicken at 4°C. Notably, we monitored zinc levels in the chicken meat, confirming a safe release of zinc without any migration of nanoparticles onto the food. This means that we can help keep raw chicken safe and fresh without compromising its integrity or quality.
Not only did we find that these functional pads inactivated the harmful bacteria, but we also noted a related increase in lactic acid production, which plays a role in further protecting the meat. Our findings open up new avenues for using zinc in food packaging, offering a way to enhance food safety without directly adding chemicals to the food itself. Overall, this study highlights the potential for nanotechnology to play a significant role in managing foodborne pathogens like Campylobacter in poultry products.
2.5
Ingredient concern
Most Useful Review
I liked the combination of ingredients, but I wish I had known how detrimental maltodextrin is before purchasing this version of Calcium & Magnesium! I hope NOW FOODS will consider removing it from their other supplements.
