NOW Supplements Rutin

Leaf extract shows anticancer promise

Based on 16 Researches

Yoon WJ, Min HJ, Cho HD, Kim HG, Park WL, et al. Bioactivity Evaluation and Phytochemical Characterization of (Thunb.) Siebold Leaf Extract. Biomedicines. 2024;12. doi:10.3390/biomedicines12122928

We examined the various health benefits of leaf extract, particularly its potential against cancer. The research revealed that the ethanol extract is rich in beneficial compounds like rutin and demonstrated significant antioxidant activities.

Notably, it selectively inhibited the growth of specific cancer cells while sparing normal cells. Additionally, treatment led to improved survival in tumor-bearing mice, showcasing its possible life-prolonging properties.

Overall, our findings suggest that this leaf extract could be a promising natural source for antioxidant and anticancer support.

Cat cancer improvement

Most Useful Review

150 people found this helpful

Absolutely helped my cat! He has liver cancer and developed severe ascites. Despite being on Lasix, he wasn't improving. After three weeks on Rutin, his fluid levels started to diminish. Recent X-rays showed no fluid in his lungs and minimal in his abdomen. This has saved his life, at least for now, making him more comfortable.

We explored the effectiveness of a newly developed, highly soluble form of rutin in treating skin problems linked to prolonged mask-wearing during the COVID-19 pandemic. This innovative clinical trial involved volunteers who wore surgical masks for extended periods.

Our findings showed that this soluble rutin significantly reduced inflammation, oxidative stress, and skin redness, while also promoting wound healing. These results indicate rutin could be an effective treatment for rosacea and other skin issues exacerbated by masks.

Overall, this treatment offers hope for those struggling with mask-related skin disorders.

Highly recommended for rosacea

Most Useful Review

110 people found this helpful

For those with rosacea, it works perfectly alongside omega and vitamin A; I recommend it to everyone.

Cardiovascular Disease details

Varicose disease relief

1 people found this helpful

Helps With Varicose Disease Veins hid after taking!

Diabetes details

Rutin safeguards the stomach from gastritis and the liver from non-alcoholic fatty liver disease. It reduces liver enzyme levels, and can even reverse insulin resistance linked to type 2 diabetes mellitus. Notably, the optimal dose is cited as 5 mg per kg of body weight once a week.

Frozen Shoulder details

1 people found this helpful

The bruises have diminished. This is an excellent product! My husband has fragile capillaries, and carrying heavy bags caused bloody bruises on his shoulders that took ages to heal. After two months of taking Rutin, no more bruises appeared, just occasional slight redness. I am pleased with the outcome and plan to regularly take it twice a year. Be healthy!

Heart Attack details

Gums and heart health

2 people found this helpful

Rutin is excellent for my gums and heart. My gums feel stronger, and flossing is easier. It effectively repairs capillaries and benefits the heart.

Heart Disease details

Improved well-being noted

I take rutin alongside Vitamin C, about twice a year in three-month courses. It's a bioflavonoid found in various plants and is crucial for enhancing circulation, combating inflammation, and is believed to assist in heart health by boosting blood vessel flexibility. Healthy blood vessels lead to improved overall well-being by facilitating blood supply to the heart and other organs.

Irritable Bowel Syndrome details

Excellent! Rutin cannot be produced by the human body and doesn’t accumulate within it—its source is ideally from unprocessed foods. This is essential for everyone, especially those with vascular issues, as a lack of vitamin P typically causes them. I suffer from chronic venous insufficiency, and after taking Rutin, I’ve noticed a reduction in pain, swelling, and cramps. The capillary network on my legs and a slight rosacea on my nose remain, but they haven't worsened. I feel a noticeable lightness in my legs. I am pleased with this medication and plan to order more.

Swollen Lymph Nodes details

52 people found this helpful

I purchased this product to use with a Vein Complex, as they complement each other. After a month, the heaviness in my legs and the swelling diminished, my protruding veins lessened, and fatigue has dissipated. I'm pleased with the results and will continue for up to three months.

Allergies details

Improved eye condition

79 people found this helpful

On the advice of a nutritionist, I take it for two reasons - to boost my immune system and to manage summer allergies, which reduces eye tearing. I take three daily and feel good.

Liver Disease details

Supports detoxification

I was prescribed Rutin to aid vascular elasticity and improve liver detoxification. I appreciated the quality; the product works well. It took several months, but after a brief break, I plan to resume taking it.

Sleep Apnea details

I took it for a friend and found that their sleep normalised and their sleep routine improved. I really appreciate this company's products.

Tinnitus details

Effective relief observed

8 people found this helpful

Pulsatile tinnitus. I tried numerous products for my pulsatile tinnitus and decided to try this one after reading some positive anecdotes. Miraculously, it works for me! I'm amazed that when I stop taking it, the tinnitus returns. After resuming, it resolves in about a week's time. This, along with Vitamin D and Ginkgo, are a lifesaver!

Bone Pain details

Improves leg sensation

8 people found this helpful

After 1-2 months of rutin, I no longer experienced pain in my legs throughout the month. My blood vessel walls felt stronger and my legs improved. While the varicose veins remain visible, the sensation is what matters, and I was able to live with it. Additionally, my gums stopped bleeding, though I believe my zinc intake also contributed to this. Remarkably, I didn't fall ill as often as before, resolving minor ailments with home remedies.

Nausea details

To support bile flow, I give this lecithin to my daughter, who has a bend in her gallbladder causing bile stagnation and nausea. I've started to administer it every morning, along with warm water on an empty stomach. The results have been remarkable! The nausea has completely disappeared, and she is doing well.

Stroke details

Rutin significantly lowers capillary permeability, thereby enhancing blood circulation and displaying anti-inflammatory properties. Studies indicate that rutin helps avert blood clots, making it suitable for individuals at risk of heart attacks and strokes.

Acne Rosacea details

Highly recommended supplement

110 people found this helpful

For those suffering from rosacea, I recommend using Rutin alongside omega and vitamin A. It works splendidly together!

Cold details

Be sure to take rutin when you have a cold; it aids in removing toxins and viruses from the blood more quickly, leading to faster recovery. It should ideally be consumed alongside vitamin C.

Abrasions details

Bruises disappeared quickly

6 people found this helpful

It acts on the vessels—fact! I purchased this on the recommendation of a friend. Surprisingly, my bruise vanished in just 5 days, whereas it typically took a minimum of 3 weeks. I’ve been on my feet all day in heels, yet there's not a hint of fatigue! My friends are astonished; they often feel worn out by the end of the day. With this medication—no fatigue! Truly, it's worth a lot! For more information about my favourite helpful products, click my name at the start of the review! Cheers to health!

Leg Cramps details

Rutin shows efficacy in leg cramps

MacLennan WJ, Wilson J, Rattenhuber V, Dikland WJ, Vanderdonckt J, et al. Hydroxyethylrutosides in elderly patients with chronic venous insufficiency: its efficacy and tolerability. Gerontology. 1994;40:45.

We explored the effects of O-(beta-hydroxyethyl)-rutosides (HR) on elderly patients dealing with chronic venous insufficiency and leg cramps. In our multicenter, double-blind, randomized, placebo-controlled trial, we treated 104 patients over six months.

Results showed that those treated with HR had a notable reduction in leg cramps and other symptoms compared to the placebo group. Improvements were significant with p-values below 0.05. While aching pains and paraesthesia did not show a marked difference, other issues like leg swelling and eczema did improve.

Overall, HR appears to provide meaningful relief for leg cramps and related symptoms in elderly patients.

Disappearance of veins

Most Useful Review

54 people found this helpful

I undertook a three-month course this spring, combined with 1000 mg of vitamin C, and the blue cobwebs of blood vessels on my legs have entirely vanished! I can confidently wear shorts and skirts this summer. This medication deserves a perfect score!

Blood Clot details

Quercetin-3-rutinoside inhibits blood clots

Based on 16 Researches

Lin L, Gopal S, Sharda A, Passam F, Bowley SR, et al. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. J Biol Chem. 2015;290:23543. doi:10.1074/jbc.M115.666180

We found that quercetin-3-rutinoside, a flavonoid, effectively inhibits blood clot formation in mice. This compound works by targeting an enzyme called protein disulfide isomerase (PDI), which is crucial for the clumping of platelets and the creation of fibrin, a key component of clots.

Our experiments revealed that quercetin-3-rutinoside binds to a specific region of PDI, altering its structure and reducing its activity. Interestingly, introducing a fragment of PDI could reverse the clot-inhibiting effects of quercetin-3-rutinoside. Overall, this study suggests that quercetin-3-rutinoside may have potential as a natural antithrombotic agent.

Impressive results

Most Useful Review

43 people found this helpful

Vessels appreciate him. I procured this for my mother and have observed significant improvement in her blood vessels' condition after using the drug alongside resveratrol and coenzyme Q10. Rutin reduces blood vessel permeability and bolsters their walls while enhancing ascorbic acid absorption. The diagnostics conducted before and after the treatment were remarkably impressive. Highly recommend this for anyone seeking to improve vascular health. Wishing everyone good health!

Bruise details

Dissipates bruising fast

37 people found this helpful

It WORKS!!! Rutin is a MUST for those who suffer from easy bruising, which can stem from medications, thin, or ageing skin. After understanding the correct dosage, I witnessed faster bruising relief. My arms & hands get these unsightly red bruises from minor bumps; this product truly helps!

Headache details

Disappeared headaches

25 people found this helpful

A good drug. I take it for my veins, and they no longer hurt—headaches have vanished as well. Be cautious to follow your doctor's advice, as the dosage mentioned on the packaging can be misleading and may lead to overdose. I experienced allergic reactions due to incorrect dosage. Proper daily intake for a person is 500mg.

Blurred Vision details

Very good lighter legs. Additionally, my legs feel brighter and my vision has improved.

Ulcer details

Rutin effectively mitigates ulcer damage

Based on 5 Researches

Abdel-Raheem IT. Gastroprotective effect of rutin against indomethacin-induced ulcers in rats. Basic Clin Pharmacol Toxicol. 2010;107:742. doi:10.1111/j.1742-7843.2010.00568.x

We investigated the impact of rutin on ulcers caused by indomethacin in a controlled study with rats. By administering rutin prior to indomethacin, we found that it effectively protected gastric tissues.

Pre-treatment with rutin led to significant reductions in ulcer severity and improved gastric health, supporting its role as a powerful antioxidant. This suggests that rutin may inhibit harmful processes like neutrophil infiltration and oxidative stress, enhancing gastric protection without affecting acidity levels.

Aids venous health

Most Useful Review

Excellent! Rutin is effective for venous insufficiency in the lower extremities, especially related to thrombosis and during pregnancy after the second trimester. It alleviates edema and pain, treats dermatitis and trophic ulcers, and supports lymphostasis and hemorrhoids. Additionally, it serves as an auxiliary treatment post-sclerotherapy and removal of varicose nodes.

Autoimmune Disorder details