NOW Supplements Taurine 500 mg

Our exploration delves into how early life stress affects anxiety and social behavior, particularly through the role of l-glutamine. We found that maternal separation in mice led to reduced levels of amino acid transporters in the gut, which in turn caused lower glutamine levels in the bloodstream. This was significant since glutamine is vital for brain functions, including the production of key neurotransmitters that influence mood and behavior.

In our findings, we noted that these low glutamine levels were linked to synaptic dysfunction in the medial prefrontal cortex, which is crucial for regulating emotional responses. Importantly, we observed that when we supplemented the mice with l-glutamine, there was noticeable improvement in their social behaviors and reduced anxiety-like symptoms. This indicates that enhancing amino acid transport through l-glutamine could be a beneficial strategy to mitigate the adverse effects of early life stress on mental health.

Overall, our research highlights a promising relationship between l-glutamine supplementation and emotional behavior improvements, pointing to a potential pathway through which gut bacteria may influence anxiety and social interactions.

9.5

Improved calmness

Most Useful Review

Who knew so much good could come from one supplement? This is a "must-have" amino acid for anyone with anxiety or stress. I've reached a new level of calm – and I mean calm, not sedated; there's a distinction. While medications like SSRIs and benzodiazepines work, they tend to numb the issue instead of addressing it. Taking Taurine at a dose of 2-3g daily has significantly improved my mood and made me feel less "alone or depressed". It takes a few days for it to fully take effect on anxiety, and a couple of weeks for depression, but it’s worth trying.

Irritable Bowel Syndrome

SCIENTIFIC SCORE

Possibly Effective

Based on 9 Researches

Glutamine reduces IBS-D symptoms

Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.

Most Relevant Research

We examined the potential of l-glutamine as a treatment for postinfectious irritable bowel syndrome, specifically focusing on patients who experience diarrhea as a primary symptom. This study was a well-structured, randomized, double-blind, placebo-controlled trial that lasted for eight weeks.

Participants were divided into two groups, receiving either 5 grams of glutamine three times a day or a placebo. We aimed to track significant improvements in IBS symptoms, particularly looking for a reduction of at least 50 points on the Irritable Bowel Syndrome Severity Scoring System (IBS-SS).

Remarkably, we found that an impressive 79.6% of patients taking glutamine met this primary endpoint, compared to just 5.8% in the placebo group—which is a 14-fold difference! Alongside this, glutamine also positively impacted secondary outcomes like daily bowel movement frequency, stool consistency, and even normalized intestinal permeability.

The results suggest that oral dietary glutamine appears to be a safe and effective option for relieving IBS symptoms related to intestinal hyperpermeability following an infection. While the findings are promising, we recommend further large-scale trials to verify these benefits and explore underlying mechanisms.

9.5

Pain alleviation

Most Useful Review

I have Leaky Gut Syndrome and find this product excellent. It has significantly relieved my pain, which I believe is healing my condition.

Atrial Fibrillation

L-Glutamine shows potential for AF

Daily Supplementation of L-Glutamine in Atrial Fibrillation Patients: The Effect on Heat Shock Proteins and Metabolites.

Most Relevant Research

We examined how L-glutamine supplementation affects patients with atrial fibrillation (AF), particularly focusing on its role in altering levels of heat shock proteins (HSP) and related metabolites. The study engaged 21 patients who were given daily doses of L-glutamine for up to six months to see its effects.

Within just three months, we observed a significant reduction in both HSP27 and HSP70 levels in participants. Specifically, HSP27 levels decreased from 540.39 to 380.69, indicating a promising shift. While HSP70 also showed a decline, its levels remained steady after the initial reduction. Notably, patients starting with high HSP27 levels tended to experience normalization in various metabolites tied to essential metabolic pathways related to carbohydrates, amino acids, and vitamins.

Our findings suggest that L-glutamine can effectively lower certain HSP levels and normalize metabolite concentrations, potentially offering a new avenue for managing AF. This insight opens the door for future research into L-glutamine as a means to enhance heart health and mitigate AF episodes.

Effective A-Fib relief

Most Useful Review

Highly recommended! L-Taurine has been extensively researched and supports evidence that its supplementation can reduce and help eliminate cardiac arrhythmias, including atrial fibrillation. My experience with Now taurine is that it calms the electrical system of the heart and has helped eliminate my atrial fibrillation. Highly recommended!

Naturopathic Approach to Functional Dyspepsia: A Case Report.

Most Relevant Research

We explored the impact of various naturopathic treatments on bloating, focusing on a case involving a young female graduate student struggling with functional dyspepsia symptoms. This student presented with issues such as bloating, abdominal pain, and reflux. Rather than relying solely on conventional medications like proton pump inhibitors, a combination of treatments was utilized, including an elimination diet, apple cider vinegar, L-glutamine powder, and a homeopathic formula.

During our observation, we noted that the patient experienced significant improvement within just one week, with most symptoms resolved by the end of the month. However, it's important to mention that while L-glutamine was a part of this holistic treatment plan, the other concurrent therapies make it challenging to pinpoint its specific influence on bloating. We recognize that patient responses can vary significantly, but this case emphasizes the potential for naturopathic strategies to bring about relief from digestive discomfort, even if the exact role of L-glutamine remains unclear.

Overall, we found that naturopathic methods can lead to substantial improvements in gastrointestinal function in a relatively short time frame, providing a hopeful avenue for those suffering from similar issues.

Calms without sleeping

Most Useful Review

I take it with meals, even though it says not to. When taken on an empty stomach, I become bloated and tired but it doesn't help me sleep like many claim. It calms me down and makes me feel relaxed, but I'm not necessarily sleepy on an empty stomach. It helps me digest food better. I will buy it again.