Products best matching Bone pain

Vitamin B Complex

9.5
Relief from pain
Most Useful Review
They truly help with bone pain! My mother suffers from neuralgia, and we struggled to alleviate her condition until discovering Solgar's B vitamins. They really work! If she misses a dose, the bone pain returns. It's frustrating to see others who don't have spine issues dismissing these vitamins. Thankfully, we found a solution that really makes a difference. Huge thanks to iHerb!
10
Energy boost
Most Useful Review
These B vitamins are effective! After switching to a vegan gluten-free diet, my B12 plummeted, and I felt awful. Solgar vitamins helped me immensely. I felt energised, my bone pain and lethargy disappeared, and I started sleeping better. Although I experienced mild tachycardia initially, it vanished quickly. These vitamins truly absorb well, and I recommend them for anyone needing support.

Vitamin D3

8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Most Relevant Research
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.

After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.

Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
9.5
Eases bone pain
Most Useful Review
An ideal solution for those struggling to swallow large capsules. After recovering from COVID, I experienced significant bone pain, but after taking Vitamin D3 for a week, the pain improved. Now my family joins me in taking it.
9.5
Relieved bone pain
Most Useful Review
I am very satisfied. My knee joint was hurting constantly, but this product relieves the pain quickly and effectively. I’ve purchased it multiple times and also bought it for my parents, with similar positive results. The joint pain has significantly alleviated, and it is much cheaper than a set of medical alternatives.
9.5
Improved well-being
Most Useful Review
Wonderful! I've been taking this vitamin for about a month, and I've noticed a significant difference in my mood and energy. My bone pain was quite severe, but since starting this supplement, my quality of life has greatly improved.

Potassium

10
Bone pain relief
Most Useful Review
Praise be to God! After suffering for over 12 years from bone pain due to salt concentration in my feet and calf muscle contractions, doctors only prescribed painkillers and antidepressants. After taking this product, I am back to my normal life, and my foot pain has completely vanished.
10
Effective capsules
Most Useful Review
Since starting keto, I experienced pulling pains in my legs. After taking these capsules, all the pain subsided. I personally consume 4 capsules a day, which has been a complete saviour for my discomfort.

Tumeric

9.5
Pain relief noted
Most Useful Review
Fantastic supplement for arthritis sufferers! I suffer from Rheumatoid arthritis in my wrists, knees, and back. After taking Curcumin, my life has become much more manageable with significantly less bone pain. I now feel nearly pain-free. This supplement energises me and motivates me to exercise, but caution is needed – too much activity can lead to acute pain. Thanks to iHerb for great prices and fresh supplements.
9.5
Joint pain management
Most Useful Review
Jarrow Curcumin 500mg is excellent for managing my bone pain from rheumatoid arthritis. I am very satisfied with this product and would highly recommend it.

Multivitamins

9.5
Effective inflammation relief
Most Useful Review
Wobenzym has excellent anti-inflammatory properties. I took it for a granuloma on my tooth root, and my bone pain and inflammation improved significantly. A friend had a similar experience with this product.
9.5
Improved sleep quality
Most Useful Review
Excellent for vegetative vascular issues. Since starting, I’ve experienced fewer exacerbations and the headaches have diminished significantly. After a couple of weeks, the constant fatigue has lessened. Now, 7 hours of sleep at night suffices, and I no longer feel the need to nap in the afternoon.

Turmeric Rhizome

9.5
Effective anti-inflammatory
Most Useful Review
Working! These drops effectively reduce inflammation and alleviate my bone pain. After two weeks of taking 30 drops twice daily, my joint pain in the shoulder and knee has diminished, and my mobility has improved. Despite being an alcoholic solution, the taste is acceptable when mixed with water, although it does stain. This product, rich in antioxidants, is beneficial for my overall health and is highly effective against various inflammation types.
9.5
Pain relief success
Most Useful Review
I love this ancient product; it really works for inflammation and bone pain.

Vitamin Bs

8
Folic acid alleviates bone pain
Folic acid relieves bone cancer pain by downregulating P2X2/3 receptors in rats.
Most Relevant Research
We aimed to understand how folic acid affects bone cancer pain, a challenging condition that isn't easily managed with typical treatments. In our study, we induced bone cancer pain in rats by injecting Walker 256 tumor cells into their tibia. To assess pain response, we measured how quickly they withdrew their paws in response to pressure and heat.

Throughout the study, we found that rats suffering from bone cancer pain showed a significant reduction in their pain thresholds. However, with continuous folic acid treatment, these thresholds improved, indicating a notable analgesic effect. We examined the levels of P2X2 and P2X3 receptors—known to play a role in pain signaling—and noticed they were elevated in the pain-afflicted rats. Remarkably, folic acid treatment resulted in a notable decrease in these receptors in both the spinal cord and relevant nerve ganglia.

This suggests that folic acid not only relieves pain but also acts by downregulating specific receptors associated with pain. We believe that our findings position folic acid as a promising option for alleviating bone cancer pain in clinical settings.
9.5
Cured back pain
Most Useful Review
Very great! After I started taking niacin for better sleep, my long-standing bone pain disappeared. I often struggled to lie on my back and woke frequently, but now I sleep soundly without discomfort. Notably, my husband began taking it too, and it has significantly aided him in battling his potential collagen disease. I was initially sceptical, but I found the pain eased almost immediately after starting niacin – it’s now essential for both of us.

Nattokinase

9.5
Leg pain reduction
Most Useful Review
I've been using nattokinase for over a month now since my legs started swelling and aching after the coronavirus. Thankfully, the pain and swelling have disappeared. I wish I had known about this sooner; it has significantly improved my leg discomfort and blood circulation. I recommend it for better blood flow!
9.5
Calf pain relief
Most Useful Review
As a fit 62-year-old, I recently suffered severe burning pain in my calf muscles due to P.A.D.s. My physician advised me to keep walking; however, I needed relief for the pain. After taking Doctors Best, Best Nattokinase, my burning pain vanished on my next walk. I now continue to take two capsules daily.

Iron

9.5
Reduced bone pain
Most Useful Review
I ordered vitamin 31 recently, and my life has improved significantly. I’ve lost around 6 pounds, and my appetite is better. I can now sleep comfortably at night without all the bone pain. Vitamin 31 has alleviated my chronic pain from sciatica and other health issues. Thank you, Dr. Clemens.
9.5
Improved health
Most Useful Review
The best hardware! I discovered this iron supplement during my pregnancy due to my anaemia. After two months, my iron deficiency was rectified, and my health improved significantly, with bone pain and dizziness disappearing. It is a mild form of iron that does not cause diarrhoea or stomach pain. If this was helpful, please like it!

Vitamin D

8
Vitamin D reduces fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
Most Relevant Research
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
9.5
Pain relief
Most Useful Review
I found this vitamin complex helpful for treating my bone pain and improving my hair and nails. After taking it, the pain has noticeably diminished. I genuinely recommend this product.

Oleuropein

9
Pain relief noted
Most Useful Review
At a dog food company, I learned that herbs, particularly olive leaves, could serve as a natural antibiotic. I was worried about this but was pleasantly surprised by the immediate effects. I bought it to help with my immunity and found that after taking it, my bone pain and swelling vanished within hours. I would like to know the appropriate dosage of Oleuropein for immunity enhancement.
9.5
Effective for pain
Most Useful Review
Trusted brand! After taking four capsules daily—two in the morning and two at night—my underarm pain and inflammation have disappeared, and my skin looks clearer too. Gaia never lets me down!

Vitamins

9.5
Effective for pain
Most Useful Review
Vitamin D is crucial for vegans, especially if they don't consume vitamin D-rich foods like mushrooms. I developed bone pain due to a deficiency from lack of sunlight. However, after taking this supplement, my pain disappeared within two weeks. It’s affordable and vegan-friendly, making it easier to ensure sufficient intake for bone health.
9.5
Reduced menstrual pain
Most Useful Review
It helped with my menstrual pain. When my periods were heavy, I struggled for two days. After starting Vitamin E, I found it much easier, likely because it aids blood flow.

Vitamin B12

9.5
Alleviated back pain
Most Useful Review
I initially took this for peripheral nerve issues, but it surprisingly alleviated my lumbar pain too. After many hours of sitting at work, I experienced discomfort in my lower back and numbness in my left foot. I shifted to methylcobalamin for relief, and taking 10000 mcg daily greatly reduced my pain. I now take it twice a day, feeling amazed by the results.
10
Postherpetic pain relief
Most Useful Review
This vitamin aids in recovering damaged nerves. I discovered that doctors prescribe B12 for neuralgia after herpes zoster, so I tried it for my family. It’s absorbed sublingually and has a delightful cherry flavour. I used to suffer from postherpetic neuralgia at night, but now I sleep well, suggesting it's effective. If the pain returns, I will use it again.

Coenzyme Q10

9.5
Fatigue relief
Most Useful Review
Struggling with poor sleep for years, I was initially sceptical of this product. However, after taking it, I found I could stay awake and active throughout the day, improving not only my mental and physical strength but also easing my bone pain. It feels like I’ve regained my youthful vitality, and I plan to continue using it.
9.5
Muscle soreness relief
Most Useful Review
I began using CoQ10 to alleviate the muscle pain caused by statin medications. Taking one capsule twice daily has completely relieved my muscle soreness and bone pain.

Biotin

9.5
Reduced hair loss
Most Useful Review
I gave birth at 35 and developed bone pain shortly after. This led to stress and hair loss. After using biotin shampoo and supplements from iHerb, the hair loss decreased significantly, which has positively impacted my mental state.
9.5
Reduced bone pain
Most Useful Review
This hair product significantly improved my hair quality over three months. Hair fall ceased, and my nails became healthier. I also noticed a reduction in bone pain, which had been troubling me due to a deficiency. The taste is pleasant, and it's much cheaper than pharmacy options. I've taken breaks but returned to it with positive results.

Probiotics

7
β-Glucans improve bone health
β-Glucans (Saccharomyces cereviseae) Reduce Glucose Levels and Attenuate Alveolar Bone Loss in Diabetic Rats with Periodontal Disease.
Most Relevant Research
We investigated how β-glucans derived from Saccharomyces cerevisiae can impact bone loss and metabolic health. In our study, diabetic rats underwent a treatment regimen of β-glucans for 28 days.

We observed that these glucans significantly reduced the loss of alveolar bone in both diabetic and non-diabetic groups, as well as lowered blood glucose and triglyceride levels. Additionally, they appeared to improve metabolic markers related to inflammation and bone health.

Overall, β-glucans show promise for enhancing both metabolic and periodontal health in diabetic conditions.
9.5
No more cramps
Most Useful Review
My favourite vitamins! I've bought a second package after experiencing severe leg cramps during pregnancy, which have since disappeared. I previously struggled with cramps at night, but these vitamins have completely resolved the issue! I don't know which vitamin helped, but now I regularly take them, even while nursing. I highly recommend them to pregnant and nursing mothers, especially if you experience leg cramps like I did.

Vitamin C

9.5
Joint pain relief
Most Useful Review
Excellent quality vitamin C which is effectively absorbed by the body. After using it, I noticed significant benefits, including relief from joint pain due to boosted collagen production. It's great for skin and hair too. With vegetarian ingredients and no animal gelatin, it's suitable for my dietary needs. The 500 tablets will last me over two months, and they are easy to swallow. This vitamin C seems to strengthen my immunity without any stomach acid issues.
9.5
Reduced joint pain
Most Useful Review
An effective immune support product. I took it for my mother to help with bone pain and joint health. She took one tablet of Vitamin C in the form of ascorbic acid after meals, three times a day. The results are commendable; her joint discomfort has decreased significantly, and she feels happier. The quality and ingredients are excellent.

Hyaluronic Acid

9.5
Effective pain relief
Most Useful Review
I have reordered this product multiple times, very satisfied with the results. It genuinely alleviates my knee pain, and I ensure to take it daily; otherwise, the discomfort returns quickly.
9.5
Significant improvement
Most Useful Review
I deal with severe bone pain from arthritic knees. Taking a double dose has helped me remarkably; within two weeks, my discomfort decreased significantly. I’ll reduce to a maintenance dose once fully recovered. Glucosamine is vital for cartilage formation and works well with chondroitin.

Ubiquinol

8.3
Effective muscle treatment
Most Useful Review
It effectively alleviates muscle pain caused by prolonged use of statin drugs, specifically addressing bone pain concerns.
9.5
Relieved muscle pain
Most Useful Review
I have mentioned this repeatedly. I was on cholesterol medication that caused my muscle pain and striated muscle melting. Since starting this supplement, I’ve experienced no symptoms. It’s somewhat pricey but still cheaper than Kaneka manufactured in Japan. Ubiquinone was ineffective for me.

Eicosapentaenoic Acid

9.5
Pain relief
Most Useful Review
My mother found relief from her bone pain using this excellent product.
8.8
Good for joints
Most Useful Review
Perfect taste, good serving of omega, and great packaging. It’s beneficial for bone pain and joint health.

Polygonum Cuspidatum Complex

9.5
Pain relief noted
Most Useful Review
About a year ago, a vein in my right leg began to throb. I have varicose veins, but no thrombophlebitis. After visiting the doctor and receiving no recommendations, I tried a course of troxerutin, which helped. Later, I took resveratrol, and within a week, the pain subsided.
9.5
Improved bone pain
Most Useful Review
Excellent! My shoulder and back pain from an injury in January faded after roughly a month on this supplement. Remarkably, my 84-year-old mother saw her longstanding shoulder pain vanish in two weeks. Her 10-year-old haemorrhoids also healed without further medication. I’m grateful for these supplements and so are my family members.

Melatonin

9.5
Relief from pain
Most Useful Review
This product has been a lifesaver for me! Due to chronic pain from osteoarthritis and fibromyalgia, sleeping is a challenge. A night without sleep exacerbates my bone pain. I was thrilled to find melatonin here; it offers me restful sleep for over eight hours, significantly enhancing my health. I plan to try a higher dose next.
8.8
Improved sleep quality
Most Useful Review
I purchase this regularly for my son, who has orthostatic disorder. I suffer from bone pain and find it difficult to sleep at night. After starting melatonin, while my waking pain hasn’t changed, my sleep quality has improved significantly. Now, I fall asleep better and wake up feeling revitalised. I recommend it to caregivers of children with orthostatic disorders – it truly helps during these challenging times.

Chromium

9.5
Improved bone pain
Most Useful Review
Royal vitamins for mere mortals. While taking them, my emotional state improved, and temporary spasms and some unknown lower abdomen pain ceased. This brand has a quality product. This is the third line of supplements my family and I have tried, and I am particularly pleased with this one for its effects on bone pain.
9
Reduced bone pain
Most Useful Review
This Tumeric with Black Pepper supplement is excellent. I've noticed an improvement in my joint function, a reduction in inflammation in my fingers, and less bone pain. I appreciate that it contains both turmeric root and an extract standardised to include 95% Curcuminoids. It's easy to swallow with no unpleasant taste.

Magnesium

8.8
No bone pain
Most Useful Review
Working magnesium is excellent. I take one pill in the evening after discovering my magnesium levels were nearly zero. Despite being an emotional person, I've noticed no muscle pain or nerve issues during its use—it's clearly effective!
8.8
Improved bone health
Most Useful Review
I appreciate the favourable packaging and cost of this magnesium supplement. After three months, I felt improvements: my bone pain and irritability diminished, and my sleep quality improved. This magnesium helped alleviate symptoms of deficiency without side effects.

Zinc

9.5
Tongue pain relief
Most Useful Review
It appears tongue pain occurs when zinc is deficient, but it works quickly for my occasional tongue pain. I take it before bed, and the pain subsides by morning.
9.5
Inflammation relief
Most Useful Review
I experienced tongue pain related to stress, but after taking one capsule over two days, the pain disappeared!

Vitamin A

9.5
Effective for bone pain
Most Useful Review
I purchased this hoping to enhance my vision and improve my mucous membranes. Surprisingly, it was remarkably effective against my bone pain associated with hernias. After starting it, my back pain resolved in just four days. When I resumed taking it after a minor back injury, it worked instantly. I feel the combination with B vitamins has a positive effect, and while I'm unsure about my eyesight, my skin appears clearer.
9.5
Prevents bone pain
Most Useful Review
I’ve managed my gout with medications for lowering uric acid, but I've read that vitamin A can help prevent bone pain. Initially, I took multiple liver oil tablets daily, but this product's high IU value allows me to take just one or two. It seems more effective when combined with 2g of vitamin C.

Elderberry

7.5
Reduced knee pain
Most Useful Review
After taking this product for about ten days, my knee pain has significantly reduced. I also take it alongside genistein.
9.5
Sore throat remedy
Most Useful Review
My throat was very sore. I drank a lot of warm water and took elderberry for two days. The pain disappeared quickly. It's a great remedy for colds.

9.5
Relaxing tea effect
Most Useful Review
I enjoy this tea for its comforting scent and taste. Its main ingredient, sacral basil (Tulsi), is known for its pain-relieving and sedative properties, which help with anxiety and relaxation. I find it relaxes me pleasantly before sleep. Although it has a sweet taste due to stevia, there’s an unusual flavour with cardamom notes. I recommend brewing it with water below boiling point to preserve its beneficial qualities. This tea has worked well for me, though I notice variations in taste with each order.
7.5
Adrenal support
Most Useful Review
I really liked this tea as it aids in achieving a good night's sleep and helps my nervous system and adrenal glands recover. However, I advise against using it during ARVI due to potential gastrointestinal effects and it may exacerbate bone pain.

Protein

9.5
Regulates blood sugar
Most Useful Review
The benefits of pumpkin seeds are well-documented, particularly when unroasted. They contain a significant amount of zinc, aiding in bone health and potentially regulating blood sugar levels. They've also been found to slow ageing and improve the condition of hair and skin. I wholeheartedly recommend this product for its multiple health benefits, including its positive effects on bone pain.
8.8
Boosts bone health
Most Useful Review
I ordered pumpkin seeds for the first time and found them to be of excellent quality. They are small, clean, and enjoyed by my family, including my children. I appreciate their beneficial properties for health, particularly in strengthening bones and combating bone pain. Regular consumption may help improve immunity and overall well-being. I'm very pleased with this product and will definitely purchase it again.

Flax Seed Oil

9.5
Effective for arthritis
Most Useful Review
I have been using this for many years to manage both inflammation and bone pain caused by arthritis, and it has been effective for me.
8
Improved muscle pain
Most Useful Review
I have noticed a significant improvement in my muscle pain since I began taking these vegan tablets, which are quite hard to find in Canada.

Red Yeast Rice

10
Effective treatment
Most Useful Review
Works well. Red yeast rice lowered my cholesterol by 30 points. Statins give me bone pain, so I've refused them. I pair this product with diet and exercise—no need for a statin.
9.5
No pain experienced
Most Useful Review
Excellent. My doctor suggested red yeast rice as an alternative to statins, which caused me significant bone pain. This product doesn't cause any pain, and I appreciate having a natural method to lower my cholesterol levels. I was already taking Co-Q10 when I began red yeast rice—it's great to find a product that combines both to avoid extra pills.

L Theanine

9.5
Healthy bone support
Most Useful Review
The quality is excellent, enhancing immunity with a generous dosage. It effectively addresses deficiencies and is very healthy. I'm pleased with my purchase; the size is convenient, and it supports bone strength. The packaging is user-friendly, especially since we receive so few vitamins from the sun, and the ingredients are superb.
9.5
Improved bone health
Most Useful Review
The quality and ingredients are exceptional with good packaging. I’ve noticed positive results, especially for health and immunity. When there’s a lack of sun and bones are weak, it’s beneficial. I recommend it to everyone, including children who may be deficient in D3. There’s real improvement.

Ginkgo

9.5
Relieved numbness
Most Useful Review
I sought this drug to improve circulation for my cervical issues, resulting in pain and numbness. After a week of taking Ginkgo and Boswellia, I no longer experience numbness or pain in my hands, and my spine feels better.
9.5
No more headaches
Most Useful Review
After struggling with severe headaches and various medical tests, I tried Ginkgo Biloba for four months. Thankfully, I no longer rely on painkillers, despite not noticing improvement in memory or thinking speed.

Astragalus Root

9.5
Pain relief noted
Most Useful Review
Frankly, with a clear conscience, I used this for 10 days due to inflammation in my kidneys, and thankfully, the pain is gone.
8.8
Significant pain reduction
Most Useful Review
For kidney issues ❤️ and any inflammation. After 2 months of taking it, the pain in my kidneys and back has significantly decreased, and my kidney indicators have nearly normalised. I also took it alongside kidney gland tissues. If my review was helpful, please give a LIKE ❤️

Quercetin

9.5
Gout relief
Most Useful Review
I suffer from recurring gout, and my last bout affected my right hand. After taking quercetin for three days, the swelling and pain have significantly reduced, and I have regained full use of my hand.
9.5
Pain-free intimacy
Most Useful Review
I experienced severe pain during sexual activity for three years, with no diagnosis from doctors. One suggested poor blood circulation, so I tried this as an anti-inflammatory. After a week, the pain disappeared. I recommend it for similar issues.

Sodium

8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Most Relevant Research
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.

After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.

Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
9.5
Effective pain relief
Most Useful Review
It does the job! Since starting at the gym last year, I endured days of bone pain afterwards. This powder (currently on my second container) significantly dulls the pain when taken after workouts. Thanks to this product, I can exercise much more frequently. I initially thought eating more meat would help, but this powder truly addresses my bone pain!

D Mannose

8
D-mannose may mitigate IVDD symptoms
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Most Relevant Research
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.

Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
9.5
Relieves bone pain
Most Useful Review
After a problematic gynaecological exam in Norway, I developed issues including bone pain and was diagnosed with cystitis. I tried antibiotics, but they only helped temporarily. However, after taking D-Mannose for three days, I could finally sleep through the night without needing to urinate, and after a week, all my symptoms, including the bone pain, vanished. If I stop taking D-Mannose, the symptoms do return.

Oregano

9.5
No more pain
Most Useful Review
I regularly order Gaia Oil of Oregano, which I use as a herbal antibiotic. I previously substituted levofloxacin due to bone pain. Since using the oil of oregano, I have felt much better and experienced no bone pain.
8.3
Pain relief noted
Most Useful Review
I purchased this product for a urinary tract infection. After taking it, my pain and burning symptoms were gone by morning. It's an excellent natural anti-inflammatory product, conveniently packaged, and easy to swallow. I've recommended it to friends.

Calcium

8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Most Relevant Research
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.

After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.

Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
9.5
Strengthened nails
Most Useful Review
NowFoods provides excellent quality calcium and magnesium. This supplement noticeably improved my nails, making them stronger and shinier. I also experienced less tooth sensitivity thanks to magnesium's calming effects. Overall, I highly recommend this supplement for strengthening nails, teeth, and providing nervous system stability.