Vitamin D levels linked to hivesThe Correlation between Serum Vitamin D and Total IgE Levels and Chronic Spontaneous Urticaria among Chinese Population: A Retrospective Study.
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We aimed to explore the relationship between vitamin D levels and chronic spontaneous urticaria (CSU), a condition characterized by persistent hives. Our study involved 101 patients suffering from CSU and 115 healthy individuals, allowing us to compare the circumstances surrounding these two groups.
We discovered that patients with CSU tended to have significantly lower levels of vitamin D compared to healthy subjects. Interestingly, we observed a negative correlation between the levels of vitamin D and the severity of hives in these patients. This means that lower vitamin D levels were associated with more severe symptoms. Conversely, total IgE levels, which often indicate allergy severity, were positively linked to the activity score of hives.
Additionally, we found that age and gender also influenced vitamin D levels. In patients, as age increased, vitamin D levels tended to rise, while being male was associated with higher vitamin D levels as well. When we conducted additional analyses, only vitamin D was significantly tied to the severity of hives, underscoring its potential importance in managing this condition.
Overall, our findings suggest that maintaining adequate vitamin D levels might play a critical role in managing chronic hives, although further studies are needed to establish a direct therapeutic benefit.