 NOW Foods, L-Carnosine, 500 mg, 100 Veg Capsules | | |
Carnosine shows neuroprotective effectsAntioxidative and anti-inflammatory protection from carnosine in the striatum of MPTP-treated mice. We explored the neuroprotective effects of carnosine in mice exposed to a Parkinson's-like condition using MPTP. By adding varying doses of carnosine to their drinking water over four weeks, we noticed that it effectively reduced damaging oxidative stress and inflammatory responses.
Notably, carnosine preserved essential dopamine levels and improved glutathione activity, indicating its potential to protect against neurodegeneration. Overall, our findings suggest that carnosine may offer a beneficial strategy in mitigating the effects of Parkinson's disease. Significant improvement noted Most Useful Review 46 people found this helpful Carnosine is truly remarkable. We have given it to our child twice, and there has been a noticeable breakthrough in their speech development, with no other changes made to their diet or medications. For an elderly relative with Parkinson's, the results are similarly impressive. They reported, "the fog in the head is gone, and there are fewer goosebumps," while continuing their standard therapy. I highly recommend trying Carnosine, as it appears quite safe unless one has serious low blood pressure or is scheduled for surgery soon. The Now Foods capsules are easy to take, being large yet manageable. I wish everyone good health! |
 NOW Foods, Acetyl-L-Carnitine, 500 mg, 200 Veg Capsules | | |
ALC shows neuroprotective potentialAcetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. The study aimed to assess whether acetyl-l-carnitine (ALC) could protect neurons in a rat model of Parkinson's disease.
We found that ALC at 200mg/kg significantly improved motor functions and reduced indicators of neuroinflammation and oxidative stress.
Additionally, it helped preserve important dopaminergic neurons and reduced cell death markers.
Overall, our results suggest ALC could serve as a supplementary treatment for Parkinson's by combating the illness's damaging processes. Tremors improved Most Useful Review 7 people found this helpful Being a vegetarian, both my mental and physical strength have diminished. However, after eating this product, my physical energy and spirits have noticeably improved, prompting me to consider purchasing it again. Now, the prices are quite reasonable. My father-in-law was recently diagnosed with Parkinson's disease, suffering from constant hand tremors. Previously, he overused his L-rotator muscle, making the symptoms more pronounced. After switching to carnitine, his hand tremors have shown improvement, although he needs to take two pills daily, which he is reluctant to do, fearing it may exacerbate his symptoms. |
 NOW Foods, Choline & Inositol, 100 Veg Capsules | | |
VCE-006.1 shows promise in Parkinson'sPreclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis. We examined the neuroprotective effects of VCE-006.1, a compound targeting the GPR55 receptor, using murine models of Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS).
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases. Preserves memory Most Useful Review 3 people found this helpful Choline enhances nerve impulse transmission, making it effective for treating nervous system disorders like Parkinson's. It boosts brain activity and supports clear memory into old age. |
 NOW Foods, 5-HTP, 100 mg, 120 Veg Capsules | | |
5-HTP shows potential sleep benefitsPreliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson's disease. We explored the impact of 5-hydroxytryptophan (5-HTP) on REM sleep behavior disorder in patients with Parkinson's disease. In a small, randomized, double-blind trial with 18 participants, we compared daily doses of 5-HTP to a placebo over four weeks. The results suggested that 5-HTP can improve sleep quality and stability without increasing REM sleep disorder episodes. However, the overall benefits were marginal and further research with larger groups and longer durations is essential to confirm these findings. Improved emotional health Most Useful Review 8 people found this helpful Following the intake of 5-HTP, symptoms of depression, apathy, and anxiety diminish; sleep becomes regular, and overall mood improves significantly. Notably, it alleviates symptoms of migraine and Parkinson's disease while enhancing concentration and overall productivity. A dosage of 50 to 300 mg per day is recommended. |
 Doctor's Best, High Absorption CoQ10 with BioPerine®, 60 Veggie Caps | | |
CoQ10 boosts motor function in miceEarly-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q. We examined how coenzyme Q10 (CoQ10) treatment impacts age-related motor issues and changes related to Parkinson's disease in mice. Aged mice displayed reduced motor functions and increased levels of a harmful protein, α-synuclein, in their brains compared to younger mice.
By giving aged mice CoQ10 in their drinking water, we found that their motor abilities improved significantly, and the harmful protein levels decreased. These findings suggest that CoQ10 can positively influence motor function and may help address early signs of Parkinson-like changes in the brain. Tremors reduced Most Useful Review 2 people found this helpful The trembling in my hands has subsided. As an 80-year-old man with a relative suffering from Parkinson’s disease, I have been taking CoQ10 for over 10 years. Although I’m unsure if it's directly responsible, the tremors in my hands, which I've experienced since my youth, have not worsened. However, I accidentally missed taking CoQ10 for some months and noticed my left hand tremors intensified. Realising my mistake, I promptly reordered and resumed taking it. After about two weeks, the tremors diminished, and I'm back to how I was before. Despite clinical trials of CoQ10 for Parkinson's seemingly failing, I remain convinced of its efficacy. |
 Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps | | |
Supports brain health Most Useful Review 1 people found this helpful N-Acetyl Cysteine (NAC) is a potent antioxidant derived from an amino acid. It plays a vital role in brain health by boosting glutathione levels, essential for protecting against oxidative damage linked to age-related conditions. NAC aids in detoxification, protects against the side effects of environmental toxins, and enhances respiratory health. Research shows it may enhance dopamine function in Parkinson's disease, alleviating symptoms. Additionally, it helps immune cells function optimally, allowing for overall health improvement. Quality product Most Useful Review I have purchased this NAC for several years and am satisfied with its quality. It provides a cost-effective alternative to pharmaceutical preparations that contain the same active ingredient. NAC is especially beneficial for chronic obstructive pulmonary disease, supporting the bronchial lining, and helps my elderly relative with Parkinson's disease by enhancing brain antioxidant processes. The capsule size is medium. |