Last update
5/10/2026
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
†
Top Medical Research Studies
8
VCE-006.1 shows promise in Parkinson's
We examined the neuroprotective effects of VCE-006.1, a compound targeting the GPR55 receptor, using murine models of Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS).
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
Read More
Most Useful Reviews
0
Worsened symptoms
6 people found this helpful
Bought it for my relative who suffers from Parkinson's, hoping it would reduce symptoms. However, shortly after taking the first capsule, her tremor severely worsened, necessitating an increase in her baseline medication. I tasted a capsule and found it unusually acidic, contrasting with inositol's sweet taste and choline's mildness. I'm quite disappointed and advise caution.
Read More
9
Preserves memory
3 people found this helpful
Choline enhances nerve impulse transmission, making it effective for treating nervous system disorders like Parkinson's. It boosts brain activity and supports clear memory into old age.
Read More
7.5
Quality and sleep improvement
Great value! Choline and inositol work synergistically as essential B vitamins for brain health. After two weeks of use, I noticed reduced nervousness and improved sleep, alongside an increase in muscle mass.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
VCE-006.1 shows promise in Parkinson's
We examined the neuroprotective effects of VCE-006.1, a compound targeting the GPR55 receptor, using murine models of Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS).
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
0
Worsened symptoms
6 people found this helpful
Bought it for my relative who suffers from Parkinson's, hoping it would reduce symptoms. However, shortly after taking the first capsule, her tremor severely worsened, necessitating an increase in her baseline medication. I tasted a capsule and found it unusually acidic, contrasting with inositol's sweet taste and choline's mildness. I'm quite disappointed and advise caution.
Read More
9
Preserves memory
3 people found this helpful
Choline enhances nerve impulse transmission, making it effective for treating nervous system disorders like Parkinson's. It boosts brain activity and supports clear memory into old age.
Read More
7.5
Quality and sleep improvement
Great value! Choline and inositol work synergistically as essential B vitamins for brain health. After two weeks of use, I noticed reduced nervousness and improved sleep, alongside an increase in muscle mass.
Read More
7.5
Supports Parkinson treatment
Choline and Inositol are vital sources of lecithin that can be immensely beneficial for Parkinson's disease, high cholesterol, and various nervous system ailments. Choline is found in nearly all living tissues and is crucial for normal synaptic transmission. Additionally, it has notable nootropic effects, being a precursor to the important neurotransmitter acetylcholine. Inositol complements choline, aiding in liver function, and has soothing properties as well. It can help alleviate tension and lower high blood pressure.
Read More
6
Improved cholesterol
23 people found this helpful
Choline and inositol, both B vitamin family members, support liver fat metabolism. I experienced increased mental clarity and energy at work after taking them. Three months later, my cholesterol normalised, cravings for sweets vanished, and I felt more purposeful rather than anxiously fidgety. Furthermore, choline may help those with Parkinson's and other conditions.
Read More
Frequently Asked Questions
7.5
Quality and sleep improvement
Great value! Choline and inositol work synergistically as essential B vitamins for brain health. After two weeks of use, I noticed reduced nervousness and improved sleep, alongside an increase in muscle mass.
6
Improved cholesterol
23 people found this helpful
Choline and inositol, both B vitamin family members, support liver fat metabolism. I experienced increased mental clarity and energy at work after taking them. Three months later, my cholesterol normalised, cravings for sweets vanished, and I felt more purposeful rather than anxiously fidgety. Furthermore, choline may help those with Parkinson's and other conditions.
0
Worsened symptoms
6 people found this helpful
Bought it for my relative who suffers from Parkinson's, hoping it would reduce symptoms. However, shortly after taking the first capsule, her tremor severely worsened, necessitating an increase in her baseline medication. I tasted a capsule and found it unusually acidic, contrasting with inositol's sweet taste and choline's mildness. I'm quite disappointed and advise caution.
7.5
Calms and soothes
This complex is excellent for promoting tranquillity. Choline and Inositol activate nerve impulse transmission in the brain while helping reduce anxiety. Beneficial for conditions like Parkinson's disease and high cholesterol, it also enhances sleep quality and emotional resilience. I've found it particularly useful when taken in cycles, supporting a healthier emotional state without mood swings.
7.5
Supports Parkinson treatment
Choline and Inositol are vital sources of lecithin that can be immensely beneficial for Parkinson's disease, high cholesterol, and various nervous system ailments. Choline is found in nearly all living tissues and is crucial for normal synaptic transmission. Additionally, it has notable nootropic effects, being a precursor to the important neurotransmitter acetylcholine. Inositol complements choline, aiding in liver function, and has soothing properties as well. It can help alleviate tension and lower high blood pressure.
8
VCE-006.1 shows promise in Parkinson's
We examined the neuroprotective effects of VCE-006.1, a compound targeting the GPR55 receptor, using murine models of Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS).
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
Our results showed that VCE-006.1 successfully reversed motor impairments and some neurodegeneration caused by toxins in PD models. However, there were no significant benefits observed in ALS models regarding neurological decline.
Overall, while VCE-006.1 demonstrated potential neuroprotection in Parkinson’s, it was ineffective in ALS, indicating the need for tailored cannabinoid therapies for different neurodegenerative diseases.
References
- Burgaz S, García C, Gonzalo-Consuegra C, Gómez-Almería M, Ruiz-Pino F, et al. Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis. Molecules. 2021;26. 10.3390/molecules26247643
