9.5
Psoriasis relief
Most Useful Review
I use this oil from head to toe after showering, and it has notably reduced my husband's psoriasis this winter. I love its effect, as it keeps our skin hydrated without oiling the roots of hair.
9.5
Soothing relief
Most Useful Review
This beautiful product has helped my mother with her severe psoriasis. It contains no alcohol or added fragrances, and its gel form makes it easy to apply.
Biotin
9.5
Healing from within
Most Useful Review
I have suffered from psoriasis vulgaris and have been taking biotin for some time. With three tablets daily, I’ve healed from within and feel that my hair and nails grow rapidly.
10
Psoriasis treatment success
Most Useful Review
My salvation! I discovered that taking biotin can completely eliminate psoriasis symptoms. I've been using it regularly, and the peeling and cracking of my skin have vanished. This truly feels like a godsend. I wholeheartedly recommend it to anyone who understands my struggles.
Evening Primrose
9.5
Helps with cramps
Most Useful Review
Excellent! Evening primrose oil is rich in omega-6 fatty acids that can alleviate PMS symptoms. It also reduces itching and inflammation in various skin conditions, including psoriasis. This oil has greatly helped with my PMS and abdominal pain, particularly on the first days. Now, I constantly use it. I highly recommend it for all women, as it protects our health and effectively eases period pains.
9.5
Promotes skin improvement
Most Useful Review
I have used evening primrose oil for more than two years, alternating it with Omega 3. It is a primary source of linoleic acid found in breast milk and has few contraindications. This oil addresses cardiovascular diseases, hormonal issues, and allergies while also helping with skin improvement and PMS relief. I took two capsules daily for three months to normalise my cycle.
Flax Seed Oil
9.5
Supports psoriasis treatment
Most Useful Review
Flaxseed oil is beneficial for the skin, brain, and circulatory system. It treats gastrointestinal conditions and chronic diseases, including psoriasis, asthma, and rheumatoid arthritis.
8.8
Effective psoriasis treatment
Most Useful Review
Very effective for hair and skin, particularly for those suffering from psoriasis and other skin conditions; it significantly aids in reducing these issues.
Tumeric
9
Curcumin nanoparticles show promise
Anti-Inflammatory Effects of Curcumin-Based Nanoparticles Containing α-Linolenic Acid in a Model of Psoriasis In Vitro.
Most Relevant Research
We investigated how Curcumin, a compound found in turmeric, may help manage psoriasis, a chronic inflammatory skin condition. Our research focused on the effects of Curcumin-based nanoparticles combined with alpha-linolenic acid (a type of omega-3 fatty acid) in an in vitro model. This model included macrophages and keratinocytes, allowing us to simulate the inflammatory responses typical of psoriasis.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
In our experiments, we found that these nanoparticles significantly reduced the expression of key inflammatory proteins in macrophages and improved the health of keratinocytes. Specifically, we saw a notable decrease in the cytokines IL-23, IL-8, and IL-6, which are often elevated in psoriasis. In keratinocytes, the treatment decreased cell death and repressed markers of ferroptosis, a recently identified process involved in psoriasis.
These promising results suggest that Curcumin-based nanoparticles could serve as a new strategy in treating psoriasis. However, more research is needed to explore their effectiveness in real-world applications before they can be recommended as a topical treatment.
9.5
Good for psoriasis
Most Useful Review
Curcumin is essential in one’s diet for its antiseptic qualities and ability to relieve inflammation. It speeds up healing, manages arthritis, and effectively addresses psoriasis, eczema, and other skin conditions. It also enhances metabolism, detoxifies the body, and helps combat depression and chronic fatigue.
Polygonum Cuspidatum Complex
9.5
Accelerates removal
Most Useful Review
Excellent Resveratrol! It's a superb addition to my treatment for psoriasis. Alongside a healthy diet and lifestyle, it helps remove skin plaques.
9
Decreased plaques
Most Useful Review
⭐️ Works for psoriasis. My plaques have decreased significantly.
Vitamins
9.5
Vitamin D3 ethosomes for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Most Relevant Research
We aimed to explore the effectiveness of a special gel infused with vitamin D3, known as an ethosome, in managing psoriasis. This inflammatory skin condition is driven by an overactive immune response, and vitamin D3 plays a crucial role in the growth and development of skin cells called keratinocytes, making it a promising treatment option.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
9
Improved immunity
Most Useful Review
In general, the role of vitamin D in the body is significant. Vitamin D is essential for everyone, especially since sunlight alone does not prevent deficiency. It is swiftly excreted and involved in various metabolic processes. Vitamin D helps strengthen the immune system, aiding in the fight against Covid-19 and reducing the likelihood of autoimmune diseases. I believe it has contributed to my psoriasis improvement.
Zinc
7
Zinc inhibits inflammatory responses
Zinc homeostasis regulates caspase activity and inflammasome activation.
Most Relevant Research
We explored the impact of zinc on psoriasis, a condition often linked with inflammation and immune response. Our attention was drawn to zinc's ability to inhibit inflammasome activation, which can trigger harmful cell death and excessive inflammation.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
9.5
Restored sense smell
Most Useful Review
Magic zinc! Zinc is essential for strengthening the immune system, cell renewal, protein synthesis, collagen formation, and addressing skin issues like psoriasis and acne. After taking zinc picolinate for a month and a half, I noticed remarkable changes: my hair stopped shedding, skin cleared up entirely, and my sense of smell returned after losing it due to Covid. I highly recommend this supplement!
Vitamin D3
9.5
Vitamin D3 ethosomes for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Most Relevant Research
We aimed to explore the effectiveness of a special gel infused with vitamin D3, known as an ethosome, in managing psoriasis. This inflammatory skin condition is driven by an overactive immune response, and vitamin D3 plays a crucial role in the growth and development of skin cells called keratinocytes, making it a promising treatment option.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
7.5
Reduced infections
Most Useful Review
Adequate intake of vitamin D3 lowers the incidence of acute respiratory infections, while deficiency increases illness risk and autoimmune conditions like psoriasis. Insufficient cholecalciferol also affects insulin secretion. This supply lasts 120 days and is cost-effective.
Fish Oil
8
EPA benefits psoriatic skin health
Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells.
Most Relevant Research
We aimed to understand how eicosapentaenoic acid (EPA) affects psoriasis, a skin condition known for causing redness, irritation, and thickened skin. By creating skin models that reflect both healthy and psoriatic conditions, we were able to assess the impact of EPA directly on lipid profiles—a key factor in skin health.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
9.5
Smoother skin
Most Useful Review
I tried this Omega for the first time and noticed results in just ten days. Previously, I used a Russian brand that was ineffective. My psoriasis has improved; the skin on my hands is smoother, and the cracks are healing. I’ve purchased a large jar since the quality is excellent, and my mother, who is hypertensive, found it beneficial too.