Last update
4/17/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 9 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
Top Medical Research Studies
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More
Most Useful Reviews
9
Mild psoriasis improvement
33 people found this helpful
Silymarin Milk Thistle has been a game-changer for me. After three weeks, my mild psoriasis is almost gone. I noticed an immediate boost in my energy from the first tablet and have even started giving it to my son with similar positive results.
Read More
7.5
Healing observed
15 people found this helpful
I have suffered from psoriasis for many years and have been serious about finding a cure since May. I followed dietary restrictions and took supplements. Despite thinking my psoriasis worsened initially, I continued during detox. After two weeks, the redness diminished and began to heal, indicating my liver has returned to normal.
Read More
9
Psoriasis improvement
12 people found this helpful
This product is great and works well. After trying it for three months, my psoriasis cleared up but returned when I stopped for a month. I’m back on it now, and it has cleared up again!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Mild psoriasis improvement
33 people found this helpful
Silymarin Milk Thistle has been a game-changer for me. After three weeks, my mild psoriasis is almost gone. I noticed an immediate boost in my energy from the first tablet and have even started giving it to my son with similar positive results.
Read More
7.5
Healing observed
15 people found this helpful
I have suffered from psoriasis for many years and have been serious about finding a cure since May. I followed dietary restrictions and took supplements. Despite thinking my psoriasis worsened initially, I continued during detox. After two weeks, the redness diminished and began to heal, indicating my liver has returned to normal.
Read More
9
Psoriasis improvement
12 people found this helpful
This product is great and works well. After trying it for three months, my psoriasis cleared up but returned when I stopped for a month. I’m back on it now, and it has cleared up again!
Read More
7.5
Excellent quality
I used this product as part of my treatment for psoriasis, and I found the quality to be excellent. The capsule size is standard.
Read More
7.5
Effective treatment
It has assisted me with psoriasis; I plan to order more.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kamel NM, El-Sayed SS, El-Said YAM, El-Kersh DM, Hashem MM, et al. Unlocking milk thistle's anti-psoriatic potential in mice: Targeting PI3K/AKT/mTOR and KEAP1/NRF2/NF-κB pathways to modulate inflammation and oxidative stress. Int Immunopharmacol. 2024;139:112781. 10.1016/j.intimp.2024.112781
- Henriet E, Abdallah F, Laurent Y, Guimpied C, Clement E, et al. Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model. JID Innov. 2023;3:100175. 10.1016/j.xjidi.2022.100175
