 NOW Foods, Choline & Inositol, 100 Veg Capsules | | |
Inositol extract curbs atherosclerosis inflammation Extract Containing -Inositol Suppresses TNF--Induced VCAM-1 Expression and Monocyte Adhesion to Endothelial Cells via Inhibition of the PTEN/Akt/GSK-3 and NF-B Signaling Pathways. We investigated how inositol, a key component found in an edible fruit extract, affects the early stages of arteriosclerosis—specifically, monocyte adhesion to endothelial cells, which is crucial in the development of cardiovascular diseases. Using human umbilical vein endothelial cells stimulated with tumor necrosis factor (TNF), we discovered that the inositol-rich extract substantially reduced the expression of vascular cell adhesion molecule-1 (VCAM-1). This reduction is important because VCAM-1 is a protein that facilitates monocyte attachment to blood vessel walls.
Our findings revealed that, through complex signaling pathways, the extract upregulated a protein called phosphatase and tensin homolog (PTEN). This process helped inhibit the activation of AKT and glycogen synthase kinase 3 (GSK-3), which are involved in inflammatory responses. Interestingly, we also saw that the extract interfered with the activation of the nuclear factor kappa B (NF-κB) pathway, further decreasing the expression of various pro-inflammatory genes.
In animal studies, the oral administration of this extract notably decreased VCAM-1 expression and monocyte infiltration in mouse models of arteriosclerosis. These compelling results point to the potential of using inositol as a nutraceutical aimed at preventing the onset of arteriosclerosis by addressing its initial inflammatory processes. Mental clarity improvement Most Useful Review 1 people found this helpful I heard this has become an essential nutrient in the United States. It converts to acetylcholine and is said to improve arteriosclerosis. After using it, I feel like my head is clearer. |
 Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels | | |
DHA stabilizes arterial plaquesInjectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability. We embarked on a quest to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact atherosclerosis, a condition where fatty deposits clog the arteries. Our focus was on a specially developed injectable formulation that delivers DHA directly to the site of arterial plaques.
Through our research, we discovered that this liposomal DHA formulation not only protects the compound but also enhances its effectiveness. When we administered it intravenously, DHA particles were specifically absorbed by macrophages—immune cells involved in the inflammation seen in atherosclerosis. This targeted delivery helps reduce inflammation and prevents the formation of foam cells, which are a hallmark of atherosclerotic plaques.
Furthermore, our analysis of the plaques revealed that the DHA treatment led to less macrophage infiltration and reduced lipid build-up, which improves overall plaque stability. In simpler terms, we observed that the treatment makes plaques less likely to rupture, which is critical in preventing serious cardiovascular problems. Additionally, sophisticated imaging techniques showed that DHA can help restore some of the healthy lipid profiles typical of earlier stages of plaque development.
In summary, using injectable DHA offers exciting potential for stabilizing arterial plaques and slowing down the progression of atherosclerosis. Given the importance of addressing this condition, our findings could pave the way for new therapeutic strategies to reduce the risk of heart-related issues. Lowered triglyceride levels Most Useful Review 4 people found this helpful I began taking Omega 3 due to its reputation for lowering blood triglycerides and decreasing the risk of arteriosclerosis and heart disease. After three and a half months, my triglycerides decreased from 96 to 67 mg/dl. My HDL dropped from 71 to 65 mg/dl, and my LDL went from 132 to 121 mg/dl. I don’t consume much fish, so I attribute these improvements to the supplement. |
 NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 100 Softgels | | |
Vitamin E shows mixed effectsEffect of atherosclerosis and the protective effect of the antioxidant vitamin E on the rabbit cerebellum. We examined the effects of vitamin E on atherosclerosis in the cerebellum of rabbits. In this study, forty rabbits were split into four groups, where specific groups received vitamin E alongside regular diets or added cholesterol.
The results revealed that cholesterol-treated rabbits experienced significant damage, evident through decreased fiber density and changes in brain cell structure. Surprisingly, while vitamin E showed some protective traits by reducing these changes, its overall impact on atherosclerosis was inconclusive. Essential supplement Most Useful Review 2 people found this helpful Vitamin E is a fat-soluble vitamin with powerful antioxidant properties, preventing lipid oxidation and helping to avert arteriosclerosis and blood clots. It may lower blood pressure and reduce LDL (bad) cholesterol. Moreover, it keeps cell membranes healthy, potentially warding off age-related diseases, hence its title as the "rejuvenating vitamin." It is an essential supplement for my health. |
 NOW Foods, E-400, 268 mg (400 IU), 250 Softgels | | |
Vitamin E shows mixed effectsEffect of atherosclerosis and the protective effect of the antioxidant vitamin E on the rabbit cerebellum. We examined the effects of vitamin E on atherosclerosis in the cerebellum of rabbits. In this study, forty rabbits were split into four groups, where specific groups received vitamin E alongside regular diets or added cholesterol.
The results revealed that cholesterol-treated rabbits experienced significant damage, evident through decreased fiber density and changes in brain cell structure. Surprisingly, while vitamin E showed some protective traits by reducing these changes, its overall impact on atherosclerosis was inconclusive. Effective for headaches Most Useful Review 3 people found this helpful Good for stiff shoulders and headaches. Vitamin E enhances blood flow in vessels, improves circulation, lowers cholesterol, and alleviates headaches, stiff shoulders, chills, and arteriosclerosis. I take it daily for my headaches and stiff shoulders. |
 NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 200 Softgels | | |
DHA stabilizes arterial plaquesInjectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability. We embarked on a quest to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact atherosclerosis, a condition where fatty deposits clog the arteries. Our focus was on a specially developed injectable formulation that delivers DHA directly to the site of arterial plaques.
Through our research, we discovered that this liposomal DHA formulation not only protects the compound but also enhances its effectiveness. When we administered it intravenously, DHA particles were specifically absorbed by macrophages—immune cells involved in the inflammation seen in atherosclerosis. This targeted delivery helps reduce inflammation and prevents the formation of foam cells, which are a hallmark of atherosclerotic plaques.
Furthermore, our analysis of the plaques revealed that the DHA treatment led to less macrophage infiltration and reduced lipid build-up, which improves overall plaque stability. In simpler terms, we observed that the treatment makes plaques less likely to rupture, which is critical in preventing serious cardiovascular problems. Additionally, sophisticated imaging techniques showed that DHA can help restore some of the healthy lipid profiles typical of earlier stages of plaque development.
In summary, using injectable DHA offers exciting potential for stabilizing arterial plaques and slowing down the progression of atherosclerosis. Given the importance of addressing this condition, our findings could pave the way for new therapeutic strategies to reduce the risk of heart-related issues. Improved circulation Most Useful Review 5 people found this helpful Omega-3 is excellent for managing triglycerides and arteriosclerosis. Since starting to take fish-derived DHA and EPA oils, my triglyceride levels returned to normal. It appears that high omega-3 fatty acid levels in red blood cells can improve flexibility and blood circulation, which may help prevent arteriosclerosis. |
 Doctor's Best, Nattokinase, 2,000 FUs, 270 Veggie Caps | | |
Nattokinase ineffective for atherosclerosisNattokinase atherothrombotic prevention study: A randomized controlled trial. We conducted a comprehensive study to investigate the effect of nattokinase on the progression of atherosclerosis, a condition that can lead to serious cardiovascular diseases. In this double-blind trial, we involved 265 participants with a median age of 65.3 years, all of whom did not show signs of existing cardiovascular disease. They were randomly assigned to receive either nattokinase or a placebo.
Over the course of a median of three years, we closely monitored changes in subclinical atherosclerosis using techniques such as carotid ultrasound. This allowed us to measure vital indicators like carotid artery intima-media thickness (CIMT) and arterial stiffness. We also tracked other health metrics, including blood pressure and various laboratory factors related to metabolism and inflammation.
Ultimately, our findings revealed that nattokinase supplementation did not significantly alter the rate of atherosclerosis progression compared to the placebo group. We also noted no meaningful changes in blood pressure or any other assessed laboratory measures. Thus, it's clear that nattokinase does not provide notable cardiovascular benefits in terms of slowing down the development of atherosclerosis for individuals at low risk of cardiovascular disease. Improves health effectively Most Useful Review 3 people found this helpful Doctors Best Nattokinase, 2,000FU is excellent! I discovered that natto supplements are beneficial for improving arteriosclerosis and maintaining good health, particularly since my blood pressure is high. I found iHerb, where I purchased a large quantity of 270 capsules at a reasonable price nearly a year ago. I've consistently bought in bulk, impressed by the quality and affordability. I owe my gratitude to iHerb for enhancing arterial health and sustaining my wellbeing. This supplement is essential for the elderly, and I plan to continue its use, hoping it remains available at a good price. I appreciate their prompt service. |
 NOW Foods, Selenium, 100 mcg, 100 Tablets | | |
Cardiovascular protection Most Useful Review 1 people found this helpful Selenium is an essential trace element beneficial to metabolic health. Once converted into selenoproteins, it fights free radicals and enhances metabolic circulation, thus supporting overall health. Selenium prevents arteriosclerosis, reduces inflammation, and mitigates cardiovascular disease risks. It also maintains thyroid function, as the thyroid contains the most selenium, and correct supplementation can avert thyroiditis. Additionally, its remarkable antioxidant properties can diminish acne incidents, promote bone health, and bolster the immune system through antioxidant support. Blood clot prevention Most Useful Review 1 people found this helpful This microelement thins the blood, prevents blood clot formation, and reduces bad cholesterol levels. Selenium effectively prevents arteriosclerosis, supports the nervous system, and has anti-inflammatory properties that alleviate asthma symptoms. I consistently use this special selenium, which is adequate for the entire family. |
 NOW Foods, Selenium, 200 mcg, 180 Veg Capsules | | |
Prevents arteriosclerosis Most Useful Review 1 people found this helpful Selenium is a trace element and essential nutrient for the human body. Once converted into selenoproteins, it helps counteract free radicals and enhance metabolic circulation, benefiting overall health. Additionally, it protects the cardiovascular system, prevents arteriosclerosis, reduces inflammatory responses, and lowers the risk of cardiovascular diseases. Supports heart health Most Useful Review Selenium is vital for maintaining heart function, offering protective and reparative qualities. A decline in blood selenium levels can hinder the body’s ability to scavenge free radicals, leading to harmful substance accumulation, elevated blood pressure, thickened blood vessel walls, and decreased elasticity, all of which can induce cardiovascular issues. With the rise in cerebrovascular diseases, scientific supplementation of selenium proves effective in preventing cardiovascular conditions, hypertension, and arteriosclerosis. |
 Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) | | |
Prevent arteriosclerosis Most Useful Review The efficacy of magnesium can avert the formation of arteriosclerosis and enhance blood supply to the myocardium, while also protecting the cardiovascular system from damage. It improves calcium absorption and supports overall health, mental clarity, nutrient absorption, and muscle endurance. A deficiency in magnesium may lead to osteoporosis in patients. Improves cardiovascular health Most Useful Review I slept well after consuming it, despite its unusual taste. Magnesium is essential for human health and cannot be produced by the body; it must be ingested through diet. It aids in maintaining nerve and muscle health, improves insomnia and relaxes the nervous system. Additionally, magnesium enhances exercise performance by alleviating lactic acid buildup and helps regulate blood pressure. It may prevent diabetes and alleviate premenstrual syndrome symptoms. Overall, magnesium effectively prevents chronic diseases and arteriosclerosis. |
 NOW Foods, Quercetin with Bromelain, 120 Veg Capsules | | |
Enhanced blood circulation Most Useful Review 30 people found this helpful This is my third purchase of quercetin with bromelain. Quercetin, a polyphenol, has antioxidant and anti-inflammatory properties, while bromelain, an enzyme from pineapple, aids digestion and possesses similar benefits. Together, they enhance blood circulation, dilate blood vessels, and help prevent arteriosclerosis. Additionally, quercetin can suppress allergy symptoms, ensuring this combination is beneficial for immunity and overall health. However, it's essential to take them in appropriate amounts to avoid overdosing. Anti-aging potential Most Useful Review 2 people found this helpful When I bought quercetin, I hoped for its anti-aging benefits and alleviation of shedding during the Covid pandemic. I also wish for improvement in my sudden hearing loss and tinnitus, ongoing for over a month. Quercetin, a flavonoid and polyphenol found in vegetables like onions, seems to improve blood flow and prevent arteriosclerosis. The 2.4cm capsule does not have a distinct taste or odour when taken with water. |
 Kyolic, Aged Garlic Extract™, Cardiovascular Health, Original Formula 100, 600 mg, 300 Capsules (300 mg Per Capsule) | | |
Health benefits noted Most Useful Review 1 people found this helpful Garlic can be challenging to consume due to its distinctive flavour and spiciness. However, as a nutritional supplement, it is highly recommended for those who struggle with it. Garlic exhibits antibacterial and sanitising properties, aids in fatigue recovery, possesses anticancer effects, improves arteriosclerosis and hypertension, inhibits allergies, enhances diabetes management, and promotes digestion. It is often referred to as a blood vessel scavenger because it helps lower blood pressure and cholesterol levels within blood vessels. Effective for twitching Most Useful Review This product has been reliable for a long time, even though it appears to be made overseas. The small capsules are very easy to swallow. I take it primarily for its blood thinning effect and to prevent arteriosclerosis. Since I began using it, the twitching blood vessels I occasionally experienced have vanished without me realising it. |
 NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels | | |
Convenient prevention Most Useful Review 1 people found this helpful I find garlic oil to be a convenient and effective option. Its active ingredient, "ajoene," promotes blood flow to the brain, while allicin combats bacteria and offers antioxidant and anti-inflammatory properties, all contributing to lower blood pressure and maintaining lipoprotein balance. It prevents and treats arteriosclerosis. Moreover, I believe that regular exercise can bolster my strength and immune system to ward off fatigue. Consuming garlic oil is much easier than eating raw garlic, making it a great choice. Supports recovery Most Useful Review I expect garlic oil to aid in fatigue recovery for three reasons: it enhances immunity, thins blood, and supports cardiovascular health. The allyl sulfide in garlic oil boosts immunity and promotes white blood cell activity, attacking pathogens while allicin helps lower cholesterol and triglycerides, ensuring supple blood vessels. This contributes to preventing arteriosclerosis and myocardial infarction by inhibiting clots. Additionally, allyl sulfide aids in lactic acid decomposition for fatigue recovery. It's crucial to adhere to recommended dosages, as excessive intake may lead to gastrointestinal issues or bad breath. |
 NOW Foods, Mega D-3 & MK-7, 5,000 IU / 180 mcg, 60 Capsules | | |
Promotes arteriosclerosis prevention Most Useful Review Excellent! I take it regularly as it helps prevent arteriosclerosis. One in the morning and one in the evening. Reduces arteriosclerosis risk Most Useful Review Supports bone strength – Vitamin D3, known as the “sunshine vitamin,” is the biological form of vitamin D supplied by the sun. D3 aids the body in absorbing calcium, while K2 (like MK7) ensures calcium is directed into bones rather than joints and arteries, thereby diminishing the likelihood of arteriosclerosis. A fantastic product. |
 NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels | | |
Great for brain health Most Useful Review 1 people found this helpful Sunflower lecithin is excellent for producing neurotransmitters and is beneficial for brain health while preventing arteriosclerosis. I am particularly fond of Van Gogh. Very effective Most Useful Review I avoid arteriosclerosis and lower blood pressure and cholesterol by taking it with fish oil. The effect is excellent. |
 NOW Foods, Astaxanthin, 4 mg, 90 Softgels | | |
Positive eye strain relief Most Useful Review 1 people found this helpful I take this to prevent eye strain and arteriosclerosis. With its strong antioxidant effect, it's beneficial for the eyes, brain, blood vessel rejuvenation, and anti-aging. As I become more aware of my age, I use it to maintain my physical strength, health, and beauty. Yes, it has a fishy smell. I've been using this along with lutein and zeaxanthin for my eye strain, and I believe it’s helping! I encourage finishing this bottle and moving on to the next; it’s an essential supplement. Comprehensive health benefits Most Useful Review Astaxanthin is a potent antioxidant, boasting a quenching ability that surpasses vitamin E and beta-carotene. Its antioxidant action aids in preventing photoaging, improving wrinkles and skin barrier function, while also supporting eye health and reducing fatigue. Key benefits include preventing arteriosclerosis and enhancing blood circulation. Furthermore, it promotes recovery from fatigue, boosts immunity, and protects brain function. Due to its numerous beneficial effects, astaxanthin is widely used as a health and beauty supplement. |
 NOW Foods, Resveratrol, 200 mg, 120 Veg Capsules | | |
Heart health boost Most Useful Review 7 people found this helpful Resveratrol is a powerful natural antioxidant that protects against coronary heart disease and arteriosclerosis. It also aids in reducing cholesterol, alleviating gout and arthritis, and has aesthetic benefits like slowing skin ageing. Now Foods' Resveratrol Natural offers convenient 200 mg capsules for easy daily intake. I highly recommend this product! Disease prevention support Most Useful Review 6 people found this helpful Great! I've used it for years as Resveratrol acts as a natural antioxidant, protecting against diseases. It serves as a preventive measure against coronary diseases, arteriosclerosis, and aids in lowering cholesterol. |