Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Biotin
10,000 mcg
33,333%
Calcium (as Calcium Carbonate)
96 mg
7%
Top Medical Research Studies
4
Low-dose biotin effects minimal
We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Read More
8
We examined the complex interaction between biotin treatment and thyroid function in a unique case of a child with both trisomy 21 and partial biotinidase deficiency. The study shed light on how biotin supplementation—needed for treating biotinidase deficiency—can interfere with thyroid hormone assessments. This interference led to a misleading "normal" thyroid-stimulating hormone (TSH) result early in the infant’s life, which delayed the diagnosis of congenital hypothyroidism.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
Read More
Most Useful Reviews
9
New hair growth
3 people found this helpful
It works! These genuinely work! I have hypothyroidism, and my hair falls out in clumps due to hormonal fluctuations. After stopping the weight loss pill Alli, I started taking biotin every night along with a multivitamin. Within weeks, I noticed new hair growth. My hair has grown about 4 inches and is now healthier and thicker. I highly recommend giving it a try; you should see results in around two months.
Read More
9
Prevented baldness
My hair, skin, and nails depend on biotin! This isn’t my first order, and I've experienced its powerful effects. Despite severe hair thinning from hypothyroidism, biotin has truly saved me from baldness. I take it in courses and also include zinc, but I can't live without a B vitamin complex. With ongoing health concerns, vitamins are essential for recovery.
Read More
7.5
Reduced hair loss
12 people found this helpful
⭐ ⭐ ⭐ A must for skin, hair and nails ⭐ ⭐ ⭐ My routine: AM: Brush softly 50 times then wash. PM: Brush softly 50 times, then apply minoxidil. I commenced this routine three months ago, and it seems effective. My hair loss has diminished, and I’m optimistic it will continue. For those experiencing hypothyroidism, this could be beneficial. As the dose is high, I checked with 21st Century about splitting it, and they affirmed it was a good idea. If this helps you, please give a thumbs up. Thank you!
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
- All Researches
8
We examined the complex interaction between biotin treatment and thyroid function in a unique case of a child with both trisomy 21 and partial biotinidase deficiency. The study shed light on how biotin supplementation—needed for treating biotinidase deficiency—can interfere with thyroid hormone assessments. This interference led to a misleading "normal" thyroid-stimulating hormone (TSH) result early in the infant’s life, which delayed the diagnosis of congenital hypothyroidism.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
Read More
4
Low-dose biotin effects minimal
We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
New hair growth
3 people found this helpful
It works! These genuinely work! I have hypothyroidism, and my hair falls out in clumps due to hormonal fluctuations. After stopping the weight loss pill Alli, I started taking biotin every night along with a multivitamin. Within weeks, I noticed new hair growth. My hair has grown about 4 inches and is now healthier and thicker. I highly recommend giving it a try; you should see results in around two months.
Read More
9
Prevented baldness
My hair, skin, and nails depend on biotin! This isn’t my first order, and I've experienced its powerful effects. Despite severe hair thinning from hypothyroidism, biotin has truly saved me from baldness. I take it in courses and also include zinc, but I can't live without a B vitamin complex. With ongoing health concerns, vitamins are essential for recovery.
Read More
7.5
Reduced hair loss
12 people found this helpful
⭐ ⭐ ⭐ A must for skin, hair and nails ⭐ ⭐ ⭐ My routine: AM: Brush softly 50 times then wash. PM: Brush softly 50 times, then apply minoxidil. I commenced this routine three months ago, and it seems effective. My hair loss has diminished, and I’m optimistic it will continue. For those experiencing hypothyroidism, this could be beneficial. As the dose is high, I checked with 21st Century about splitting it, and they affirmed it was a good idea. If this helps you, please give a thumbs up. Thank you!
Read More
7.5
Improved mood
I've had hypothyroidism for over 10 years and often faced issues absorbing B vitamins. I bought biotin a month ago, and I've decided to continue using it as I've felt significantly better, with more energy and an improved mood.
Read More
7.5
Thicker hair
Great value for money! My hair stopped falling out, and my lashes are longer. I’ve completed my second bottle. With hypothyroidism, hair loss is expected, but biotin has truly helped.
Read More
Frequently Asked Questions
9
New hair growth
3 people found this helpful
It works! These genuinely work! I have hypothyroidism, and my hair falls out in clumps due to hormonal fluctuations. After stopping the weight loss pill Alli, I started taking biotin every night along with a multivitamin. Within weeks, I noticed new hair growth. My hair has grown about 4 inches and is now healthier and thicker. I highly recommend giving it a try; you should see results in around two months.
7.5
Improved mood
I've had hypothyroidism for over 10 years and often faced issues absorbing B vitamins. I bought biotin a month ago, and I've decided to continue using it as I've felt significantly better, with more energy and an improved mood.
6
Better hair quality
With hypothyroidism, my hair was deteriorating, but after starting to take biotin, I noticed an immediate improvement in my hair's condition.
7.5
Reduced hair loss
12 people found this helpful
⭐ ⭐ ⭐ A must for skin, hair and nails ⭐ ⭐ ⭐ My routine: AM: Brush softly 50 times then wash. PM: Brush softly 50 times, then apply minoxidil. I commenced this routine three months ago, and it seems effective. My hair loss has diminished, and I’m optimistic it will continue. For those experiencing hypothyroidism, this could be beneficial. As the dose is high, I checked with 21st Century about splitting it, and they affirmed it was a good idea. If this helps you, please give a thumbs up. Thank you!
7.5
Thicker hair
Great value for money! My hair stopped falling out, and my lashes are longer. I’ve completed my second bottle. With hypothyroidism, hair loss is expected, but biotin has truly helped.
9
Prevented baldness
My hair, skin, and nails depend on biotin! This isn’t my first order, and I've experienced its powerful effects. Despite severe hair thinning from hypothyroidism, biotin has truly saved me from baldness. I take it in courses and also include zinc, but I can't live without a B vitamin complex. With ongoing health concerns, vitamins are essential for recovery.
7.5
Less hair fall
I drink biotin for hair loss associated with hypothyroidism. I’ve recently started taking it less often and have noticed a significant reduction in hair loss.
4
Low-dose biotin effects minimal
We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
8
We examined the complex interaction between biotin treatment and thyroid function in a unique case of a child with both trisomy 21 and partial biotinidase deficiency. The study shed light on how biotin supplementation—needed for treating biotinidase deficiency—can interfere with thyroid hormone assessments. This interference led to a misleading "normal" thyroid-stimulating hormone (TSH) result early in the infant’s life, which delayed the diagnosis of congenital hypothyroidism.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
References
- Angelopoulos N, Paparodis RD, Androulakis I, Anagnostis P, Boniakos A, et al. The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?. Thyroid Res. 2023;16:18. doi:10.1186/s13044-023-00162-8
- Feldt MM. Delayed Diagnosis of Congenital Hypothyroidism in a Child with Trisomy 21 and Biotinidase Deficiency and Successful Use of Levothyroxine Sodium Oral Solution. Case Rep Endocrinol. 2020;2020:8883969. doi:10.1155/2020/8883969
