Vitamin Bs
9
Thiamin improves memory in hypothyroidism
Our study focused on how thiamin, also known as Vitamin B1, can help with learning and memory issues caused by hypothyroidism. We designed an experiment using 50 rats, which we treated with propylthiouracil to induce hypothyroidism and then supplemented with varying doses of thiamin. Over a period of seven weeks, we assessed the rats’ abilities to remember and learn through standard tests like the Morris water maze and passive avoidance tasks.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
9.5
Stopped hair loss
Most Useful Review
After three months of taking this supplement, my hair loss has stopped, and my nails are stronger. I have chemical sensitivity and hypothyroidism, both of which contribute to hair loss. This supplement has a higher content of ingredients compared to Japanese biotin, and it has helped my hair and skin feel better. I even take more on days with strong chemicals due to its detoxifying properties.
Kelp
8
Kelp shows potential in hypothyroidism
We investigated the effectiveness of a mix of hot water extracts from Astragalus membranaceus and Laminaria japonica in protecting against hypothyroidism caused by propylthiouracil in rats. The study showed that this combination, when given in doses of 100, 200, and 400 mg per kg, significantly reduced thyroid and liver abnormalities caused by the drug.
The results suggest that the mix, rich in iodine and ferulic acid, can positively influence thyroid hormone production and help protect liver function. While these findings are promising, they hint at the potential of this extract as a supportive treatment for hypothyroidism.
The results suggest that the mix, rich in iodine and ferulic acid, can positively influence thyroid hormone production and help protect liver function. While these findings are promising, they hint at the potential of this extract as a supportive treatment for hypothyroidism.
9.5
Immediate energy boost
Most Useful Review
Very effective iodine. After just three days on one capsule, my hair stopped falling out, and I instantly felt more energetic with fewer headaches. I've reordered, as this iodine is far superior to Iodomarin. I’ve also started my mother on it for her subclinical hypothyroidism. It's effective, but the dose is high; for prophylactic use, one capsule weekly may suffice. Organic iodine gets absorbed precisely, preventing overdose.
Potassium
9
We embarked on a study to understand the effects of potassium bromate on healing gastric ulcers in rats that underwent thyroidectomy, which models a state of hypothyroidism. By treating groups of rats with potassium bromate or thyroxine, we compared the healing process in both typical and thyroid-removed conditions.
The results revealed that potassium bromate appeared to enhance the healing of gastric ulcers in hypothyroid rats. We observed a decrease in gastric inflammation and swelling, suggesting improved recovery. Additionally, markers for organ health and blood conditions remained normal, and there was a notable reduction in harmful substances linked to cellular stress.
Our findings indicate that low doses of potassium bromate might mimic the effects of thyroid hormone treatment in promoting gastric healing. This is a promising insight into how potassium can potentially support recovery in conditions marked by low thyroid hormone levels, offering a unique perspective on treatment alternatives.
The results revealed that potassium bromate appeared to enhance the healing of gastric ulcers in hypothyroid rats. We observed a decrease in gastric inflammation and swelling, suggesting improved recovery. Additionally, markers for organ health and blood conditions remained normal, and there was a notable reduction in harmful substances linked to cellular stress.
Our findings indicate that low doses of potassium bromate might mimic the effects of thyroid hormone treatment in promoting gastric healing. This is a promising insight into how potassium can potentially support recovery in conditions marked by low thyroid hormone levels, offering a unique perspective on treatment alternatives.
9.5
Reduced thirst feelings
Most Useful Review
I found this iodine supplement amazing as it contains calcium iodide rather than kelp, which can vary in iodine content. Since I have hypothyroidism, I often experienced dehydration despite drinking enough water, which left me feeling thirsty. This supplement supports my thyroid function and remarkably reduces my thirst. It's a very effective product, providing honest feedback without any embellishments. I appreciate it!
L Theanine
7
Myo-inositol's limited impact on thyroid
We explored the effectiveness of myo-inositol in combination with selenium for treating autoimmune thyroiditis (AIT) and how this combination impacts thyroid hormone levels. Through a systematic review and meta-analysis of various studies, we found that supplementing selenium with myo-inositol led to a significant reduction in thyroid-stimulating hormone (TSH) levels compared to taking selenium alone. Additionally, we observed a notable decline in thyroglobulin antibodies (TgAb) in the combined treatment group.
However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
8.8
Improved concentration
Most Useful Review
I have hypothyroidism but enjoy coffee in the morning, paired with L-Theanine, which enhances the effect. Caffeine alone causes a sharp energy spike followed by a drop, whereas combining it with L-Theanine results in a smoother, longer-lasting boost in focus and mood. It aids my memory, suppresses appetite, and doesn’t induce drowsiness. Occasionally, I take it with melatonin at night to help me sleep, always on an empty stomach for greater potency. I love it and always keep it stocked!
Omega 3 Fish Oil
8
We observed the effects of Omega 3 fatty acids (O3FA) on hypothyroidism caused by the endocrine-disrupting chemical Bisphenol F (BPF) in a controlled study with male Wistar rats. The rats were divided into four groups: a control group, a BPF-only group, and two intervention groups receiving different doses of O3FA alongside BPF.
Our findings revealed that both low and high doses of O3FA significantly improved sperm quality, hormonal levels, and antioxidant defenses, which were adversely affected by BPF. Notably, the treatment with O3FA restored important enzymes and prevented harmful increases in certain inflammatory markers, showing its protective role against testicular dysfunction linked to thyroid issues.
Overall, this study indicates that incorporating Omega 3 fatty acids could be an effective strategy to counteract the negative impacts of BPF-induced hypothyroidism and support male reproductive health.
Our findings revealed that both low and high doses of O3FA significantly improved sperm quality, hormonal levels, and antioxidant defenses, which were adversely affected by BPF. Notably, the treatment with O3FA restored important enzymes and prevented harmful increases in certain inflammatory markers, showing its protective role against testicular dysfunction linked to thyroid issues.
Overall, this study indicates that incorporating Omega 3 fatty acids could be an effective strategy to counteract the negative impacts of BPF-induced hypothyroidism and support male reproductive health.
9.5
Miraculous skin improvement
Most Useful Review
My first omega-3, recommended by my endocrinologist, needed for my hypothyroidism. Initially, my skin was extremely dry and sensitive, but after taking Omega for about a month, I noticed a significant improvement. My skin now remains better hydrated even after washing. I take two capsules daily after meals. I previously tried Finnish and Norwegian omega, but I prefer this one, despite the large capsule size. Highly recommend it!
Inositol
7
Myo-inositol's limited impact on thyroid
We explored the effectiveness of myo-inositol in combination with selenium for treating autoimmune thyroiditis (AIT) and how this combination impacts thyroid hormone levels. Through a systematic review and meta-analysis of various studies, we found that supplementing selenium with myo-inositol led to a significant reduction in thyroid-stimulating hormone (TSH) levels compared to taking selenium alone. Additionally, we observed a notable decline in thyroglobulin antibodies (TgAb) in the combined treatment group.
However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
9.5
Effective treatment
Most Useful Review
Inositol is a vital precursor to phospholipids, essential components of cell membranes. It aids in nutrient transfer and fat conversion. This specific product contains crystalline inositol and has been effectively used in treating hypothyroidism. I found it to be one of the best options available after testing many samples, and I wholeheartedly recommend it!
Ashwagandha
9
We explored the effects of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, in a study designed to understand its role in overcoming hypothyroidism-induced neuronal apoptosis, especially during crucial cerebellar development. Our research involved supplementing pregnant and lactating rats with a mixture of DHA and eicosapentaenoic acid (EPA) while inducing hypothyroidism using methimazole.
By examining the cerebellum of pups at postnatal day 16, we observed that DHA supplementation significantly curbed DNA fragmentation and reduced caspase-3 activation, both markers of cell death. This protective effect seemed linked to DHA's ability to lower levels of pro-apoptotic proteins like Bax, which typically rise when thyroid hormones are deficient.
Furthermore, we found that omega-3 fatty acids boosted levels of protective proteins like Bcl-2 and Bcl-x(L), which are usually suppressed in hypothyroid conditions. DHA also helped restore important signaling pathways impacted by hypothyroidism, such as phospho-AKT, phospho-ERK, and phospho-JNK, without affecting myelin basic protein levels, which are responsive to thyroid hormones.
Overall, our findings suggest that omega-3 fatty acids, particularly DHA, have a significant anti-apoptotic role in the developing brain during periods of thyroid hormone deficiency.
By examining the cerebellum of pups at postnatal day 16, we observed that DHA supplementation significantly curbed DNA fragmentation and reduced caspase-3 activation, both markers of cell death. This protective effect seemed linked to DHA's ability to lower levels of pro-apoptotic proteins like Bax, which typically rise when thyroid hormones are deficient.
Furthermore, we found that omega-3 fatty acids boosted levels of protective proteins like Bcl-2 and Bcl-x(L), which are usually suppressed in hypothyroid conditions. DHA also helped restore important signaling pathways impacted by hypothyroidism, such as phospho-AKT, phospho-ERK, and phospho-JNK, without affecting myelin basic protein levels, which are responsive to thyroid hormones.
Overall, our findings suggest that omega-3 fatty acids, particularly DHA, have a significant anti-apoptotic role in the developing brain during periods of thyroid hormone deficiency.
9.5
Optimises thyroid function
Most Useful Review
Ashwagandha is renowned for stimulating the thyroid gland and promoting its optimal function, which is beneficial for those with hypothyroidism. Additionally, it effectively reduces stress and anxiety, helping individuals manage cortisol levels and maintain calm throughout the day. Its antioxidant properties also assist in detoxifying the body.
Vitamins
8
We evaluated the effects of vitamin D3 supplementation on hypothyroidism, specifically in patients with Hashimoto's thyroiditis (HT). Our analysis involved 12 randomized controlled trials, comparing the outcomes of individuals receiving vitamin D3 against those given a placebo or no treatment at all.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
9.5
Chronic fatigue gone
Most Useful Review
I bought this complex of vitamins D and K for the first time and am very pleased. It's particularly beneficial for those with thyroid issues like AIT and hypothyroidism. The antioxidants included have enhanced my well-being. I feel energetic, my mood is high, and chronic fatigue has vanished! I highly recommend these vitamins!!
Vitamin B Complex
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.
The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
8.8
Improved performance.
Most Useful Review
Very good help with hypothyroidism; it also helps correct anaemia. After just one course, my performance improves, and we are satisfied.
Folic Acid
7
Folic acid mitigates lithium effects
We examined the effects of folic acid on cognitive and biochemical outcomes in newborn rats whose mothers were exposed to lithium during pregnancy. Our study involved pregnant rats given various doses of lithium and folic acid.
Results suggested that high lithium doses resulted in neurodevelopmental issues and thyroid dysfunction. However, folic acid, particularly at higher doses, seemed to reduce anxiety and memory problems linked to lithium.
These findings highlight the potential protective role of folic acid, though precautions with lithium during pregnancy remain essential.
Results suggested that high lithium doses resulted in neurodevelopmental issues and thyroid dysfunction. However, folic acid, particularly at higher doses, seemed to reduce anxiety and memory problems linked to lithium.
These findings highlight the potential protective role of folic acid, though precautions with lithium during pregnancy remain essential.
9.5
Highly absorbable
Most Useful Review
Highly absorbable and well tolerated, I am taking this supplement following a vitamin B9 deficiency linked to my hypothyroidism. Methylfolate is the active form of folic acid, directly assimilated by the body and crossing the blood-brain barrier. This product is of good quality and easy to take.
Selenium
We conducted a study to investigate how supplementation with certain micronutrients, like selenium, impacts thyroid function in patients with hypothyroidism. Over the course of eight weeks, 104 participants were either given a combination of selenium, zinc, magnesium, vitamins A, C, E, and a placebo while continuing their treatment with levothyroxine and vitamin D.
After the intervention, we measured various factors, including thyroid hormone levels, cholesterol, and overall quality of life. Though we observed some changes in insulin resistance and quality of life, the study did not show conclusive evidence that selenium alone significantly improves thyroid function or metabolic outcomes in hypothyroid patients.
Our findings suggest that while additional nutrients may offer some benefits, more extensive clinical trials are necessary to understand their role better in managing hypothyroidism. This study contributes to the ongoing discussion on the importance of nutritional supplements in thyroid health, specifically the potential effects of selenium alongside other vitamins and minerals.
After the intervention, we measured various factors, including thyroid hormone levels, cholesterol, and overall quality of life. Though we observed some changes in insulin resistance and quality of life, the study did not show conclusive evidence that selenium alone significantly improves thyroid function or metabolic outcomes in hypothyroid patients.
Our findings suggest that while additional nutrients may offer some benefits, more extensive clinical trials are necessary to understand their role better in managing hypothyroidism. This study contributes to the ongoing discussion on the importance of nutritional supplements in thyroid health, specifically the potential effects of selenium alongside other vitamins and minerals.
8.8
Reduced hair loss
Most Useful Review
I have been taking selenium for two years as prescribed by my endocrinologist for hypothyroidism, with 1 tablet at breakfast. I chose this brand for being yeast-free, affordable, and containing selenomethionine, which is better absorbed. I’ve noticed less hair loss and more energy; even with hormones, I previously faced chronic fatigue. It's especially effective in tandem with Vitamin D. Selenium is a powerful antioxidant critical for glutathione’s functioning and assists in removing heavy metals and chemicals from the body.
Vitamin A
7
Micronutrients may improve quality of life
We conducted a study to explore how certain micronutrients, specifically vitamin A, might influence thyroid function and the overall well-being of individuals suffering from hypothyroidism. In this randomized, controlled trial, 104 participants already on levothyroxine and vitamin D were assigned to receive either a mix of micronutrient supplements or a placebo for eight weeks.
Among the micronutrients tested, vitamin A was one of several key components we were curious about. While we found that the group receiving these supplements showed some improvement in insulin resistance and aspects of their quality of life, the specific impact of vitamin A alone on thyroid function was not clearly isolated. We did not observe significant benefits related directly to thyroid hormone levels, which suggests that additional research is necessary to determine the precise role vitamin A plays in managing hypothyroidism.
In conclusion, while our findings hint at the potential benefits of a broader approach to micronutrient supplementation, they leave room for future investigations to clarify the specific contributions of vitamin A and its interactions with other nutrients.
Among the micronutrients tested, vitamin A was one of several key components we were curious about. While we found that the group receiving these supplements showed some improvement in insulin resistance and aspects of their quality of life, the specific impact of vitamin A alone on thyroid function was not clearly isolated. We did not observe significant benefits related directly to thyroid hormone levels, which suggests that additional research is necessary to determine the precise role vitamin A plays in managing hypothyroidism.
In conclusion, while our findings hint at the potential benefits of a broader approach to micronutrient supplementation, they leave room for future investigations to clarify the specific contributions of vitamin A and its interactions with other nutrients.
8.8
Effective treatment
Most Useful Review
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.
Magnesium
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
9.5
Calmness and relief
Most Useful Review
This product genuinely works well for my nervous system. After taking this magnesium alongside B vitamins, I achieved almost complete calmness. Caution is necessary to avoid overdosing, which can lead to lowered blood pressure; for me, it notably improved my stool regularity, a common issue with hypothyroidism. Although I experienced constipation previously, I needed to control my intake and had to stop after two weeks due to an accidental overdose. Nevertheless, I am pleased with the results and plan to order more.
Zinc
7
Zinc's uncertain role in hypothyroidism
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
8.8
Improved life quality
Most Useful Review
I have hypothyroidism and a zinc deficiency, resulting in various health issues. I experience hair loss, fatigue, and more. Zinc intake is crucial for thyroid function and hormone regulation. I opt for zinc chelate as its bioavailability is higher. While other medications also contribute to my treatment, zinc has significantly enhanced my quality of life. I also provide it to my family to bolster their immunity.
N Acetyl Cysteine Nac
7
We explored the protective role of brewer's yeast in combating the harmful effects of methimazole-induced hypothyroidism. In a study involving 48 rats, we divided them into control and experimental groups to assess the impact of methimazole and brewer's yeast on adrenal glands.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
9.5
Antibodies reduced
Most Useful Review
Excellent! Doctor's Best Acetylcysteine (NAC Detox Regulators) aids the absorption of glutathione, a crucial antioxidant in healthy cells. It has been proven that N-acetylcysteine enhances glutathione production. Selenium and molybdenum are vital for this process, supporting detoxification and energy production. The capsules are medium-sized, tasteless, and easy to swallow. I took one each morning on an empty stomach. NAC helped reduce my antibodies; I have hypothyroidism and finished a few jars. I recommend it.
Vitamin D
7
Vitamin D and hypothyroidism explored
We conducted a thoughtful exploration into how vitamin D and other micronutrients might influence hypothyroidism, particularly looking at thyroid function, metabolism, and quality of life. In this double-blind, randomized controlled trial, we involved 104 patients who were already receiving levothyroxine for their hypothyroidism. They were split into two groups; one received a combination of micronutrients, including vitamin D, while the other group received a placebo.
After eight weeks, we observed some impacts on insulin resistance and quality of life among those receiving the micronutrient supplement, suggesting that these nutrients could play a role in improving overall well-being in hypothyroid patients. However, while vitamin D is part of the treatment, we found it challenging to isolate its direct effect due to its combination with other nutrients.
Ultimately, while our findings indicate potential benefits, they also emphasize the need for further clinical trials to confirm these results and better understand the role of vitamin D in managing hypothyroidism.
After eight weeks, we observed some impacts on insulin resistance and quality of life among those receiving the micronutrient supplement, suggesting that these nutrients could play a role in improving overall well-being in hypothyroid patients. However, while vitamin D is part of the treatment, we found it challenging to isolate its direct effect due to its combination with other nutrients.
Ultimately, while our findings indicate potential benefits, they also emphasize the need for further clinical trials to confirm these results and better understand the role of vitamin D in managing hypothyroidism.
8.8
Increased energy levels
Most Useful Review
I switched to a simpler iodine with vitamin K and appreciate the capsule size, which is easy to swallow. The vegetable iodine dosage is high, but not fully absorbed due to my hypothyroidism. My endocrinologist approved its use, and I take it alongside selenium for better absorption. After three months, I feel increased energy and recommend it.
Acetyl L Carnitine
8
We examined how acetyl-L-carnitine influences hypothyroidism, particularly focusing on its impact on liver mitochondria. In our study, we measured the amount of messenger RNA for cytochrome oxidase subunit I in the livers of hypothyroid rats.
After treating the rats with acetyl-L-carnitine, we observed a significant increase in the mRNA levels just three hours post-treatment. This improvement in gene expression suggests that acetyl-L-carnitine may promote mitochondrial function even in altered metabolic states.
Interestingly, even rats that were pre-treated with T3, a thyroid hormone, showed similar positive effects when administered acetyl-L-carnitine. These findings lend further support to the idea that acetyl-L-carnitine can stimulate important processes in mitochondria, especially under conditions like hypothyroidism.
After treating the rats with acetyl-L-carnitine, we observed a significant increase in the mRNA levels just three hours post-treatment. This improvement in gene expression suggests that acetyl-L-carnitine may promote mitochondrial function even in altered metabolic states.
Interestingly, even rats that were pre-treated with T3, a thyroid hormone, showed similar positive effects when administered acetyl-L-carnitine. These findings lend further support to the idea that acetyl-L-carnitine can stimulate important processes in mitochondria, especially under conditions like hypothyroidism.
9.5
Feeling better
Most Useful Review
I started taking this on my endocrinologist's advice for hypothyroidism, and I feel significantly better now.
Sports Fish Oil Omegas
9
We investigated the role of eicosapentaenoic acid (EPA), an omega-3 fatty acid, in the context of hypothyroidism and its effects on brain development. Our study used a rat model where hypothyroidism was induced, allowing us to examine how EPA influences neuronal health during this critical phase of development.
Through our research, we found that supplementing EPA, along with docosahexaenoic acid (DHA), significantly reduced signs of neuronal apoptosis, which is a controlled process of cell death that can be detrimental when excessive. Specifically, we observed decreases in DNA fragmentation and activation of an important mediator of cell death—caspase-3—in the cerebella of hypothyroid pups.
One of the key findings highlighted that EPA helped counteract increases in a pro-apoptotic protein called Bax. At the same time, levels of protective proteins, such as Bcl-2 and Bcl-x(L), were restored, which are crucial in promoting cell survival. Additionally, EPA supplementation normalized several important signaling pathways affected by thyroid hormone deficiency, which play vital roles in neuronal health.
Overall, our findings contribute valuable insight into how eicosapentaenoic acid can offer protective benefits for brain development during periods of stress caused by hypothyroidism, illuminating potential therapeutic pathways for ongoing investigations.
Through our research, we found that supplementing EPA, along with docosahexaenoic acid (DHA), significantly reduced signs of neuronal apoptosis, which is a controlled process of cell death that can be detrimental when excessive. Specifically, we observed decreases in DNA fragmentation and activation of an important mediator of cell death—caspase-3—in the cerebella of hypothyroid pups.
One of the key findings highlighted that EPA helped counteract increases in a pro-apoptotic protein called Bax. At the same time, levels of protective proteins, such as Bcl-2 and Bcl-x(L), were restored, which are crucial in promoting cell survival. Additionally, EPA supplementation normalized several important signaling pathways affected by thyroid hormone deficiency, which play vital roles in neuronal health.
Overall, our findings contribute valuable insight into how eicosapentaenoic acid can offer protective benefits for brain development during periods of stress caused by hypothyroidism, illuminating potential therapeutic pathways for ongoing investigations.
9.5
Softened dry skin
Most Useful Review
I absolutely love this omega! After just a few days of taking it, the difference in my skin and nails is evident. My elbows, often very dry due to hypothyroidism, feel smoother and softer after using this omega. We take it as a family, and I appreciate that one capsule contains 1000 mg of essential fatty acids. The capsule is large but easy to swallow.
Ginkgo Biloba
7
Ginkgo biloba supports hypothyroidism treatment
We investigated how Ginkgo biloba could help balance some of the challenges faced by hypothyroid mice under conditions of oxygen deprivation. In our study, we divided male Swiss mice into five groups, where some received Ginkgo biloba, while others were treated with Levothyroxine or were left untreated as controls.
We observed that Ginkgo biloba didn’t boost thyroid hormone levels, but it helped keep TSH levels steady. After treatment, the mice showed lower blood glucose, decreased oxidative stress, and inflammation, indicating a positive shift in their biochemical balance. This suggests Ginkgo biloba may reduce harmful effects related to hypoxia and hypothyroidism.
Importantly, we noticed Ginkgo biloba affected the signaling pathways involving endothelin-1 and nitric oxide in the aorta, which are crucial for vascular health. Overall, Ginkgo biloba appears to act as a therapeutic candidate, potentially offering a natural way to support cardiovascular function in hypothyroid conditions affected by low oxygen levels.
We observed that Ginkgo biloba didn’t boost thyroid hormone levels, but it helped keep TSH levels steady. After treatment, the mice showed lower blood glucose, decreased oxidative stress, and inflammation, indicating a positive shift in their biochemical balance. This suggests Ginkgo biloba may reduce harmful effects related to hypoxia and hypothyroidism.
Importantly, we noticed Ginkgo biloba affected the signaling pathways involving endothelin-1 and nitric oxide in the aorta, which are crucial for vascular health. Overall, Ginkgo biloba appears to act as a therapeutic candidate, potentially offering a natural way to support cardiovascular function in hypothyroid conditions affected by low oxygen levels.
9.5
Improved focus
Most Useful Review
Promotes clarity and focus! After battling brain fog due to hypothyroidism for years, I was eager for a solution. My grades in my postgraduate course were barely average as I struggled to form sentences for assignments and often forgot what I had read. However, with this brand, I felt energised, focused, and my memory improved significantly. I have a positive experience every time I take it, regardless of breaks in usage. It works anytime I take it.
Alpha Lipoic Acid
9
α-Lipoic acid mitigates oxidative damage
We evaluated how α-lipoic acid might help with oxidative stress in the epididymis caused by maternal hypothyroidism during a study involving rats. Pregnant rats were divided into two groups: those that were not exposed to an antithyroid drug called carbimazole and those that were. After the pups were born, we examined the male offspring about 100 days later.
Our results showed that the rats exposed to carbimazole had increased lipid peroxidation and elevated levels of harmful oxidative stress markers in their epididymis. These rats also had lower levels of important antioxidant enzymes and an increase in sperm DNA damage. Furthermore, we noted structural changes in the epididymis, which is crucial for sperm maturation.
However, when we supplemented the affected rats with α-lipoic acid during their developmental phase, many of these negative effects were significantly reduced. This treatment helped restore normal epididymal function, likely due to α-lipoic acid's powerful antioxidant properties and its influence on hormone regulation.
Thus, our findings highlight the potential of α-lipoic acid as a beneficial treatment in mitigating the oxidative damage associated with maternal hypothyroidism in offspring.
Our results showed that the rats exposed to carbimazole had increased lipid peroxidation and elevated levels of harmful oxidative stress markers in their epididymis. These rats also had lower levels of important antioxidant enzymes and an increase in sperm DNA damage. Furthermore, we noted structural changes in the epididymis, which is crucial for sperm maturation.
However, when we supplemented the affected rats with α-lipoic acid during their developmental phase, many of these negative effects were significantly reduced. This treatment helped restore normal epididymal function, likely due to α-lipoic acid's powerful antioxidant properties and its influence on hormone regulation.
Thus, our findings highlight the potential of α-lipoic acid as a beneficial treatment in mitigating the oxidative damage associated with maternal hypothyroidism in offspring.
8.8
Weight loss support
Most Useful Review
I have autoimmune thyroiditis, which has led to insulin resistance and hypothyroidism. Alpha lipoic acid has aided my weight loss, as many with AIT, like myself, face challenges in controlling their weight. Recommended by my doctor, I used it to manage insulin resistance. After three months, I lost 9 kg, despite not being strict with my diet and having decreased physical activity. I recommend it to anyone with a similar diagnosis who is struggling with weight loss.
Probiotics
7
We explored the protective role of brewer's yeast in combating the harmful effects of methimazole-induced hypothyroidism. In a study involving 48 rats, we divided them into control and experimental groups to assess the impact of methimazole and brewer's yeast on adrenal glands.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
9.5
Effective for digestion
Most Useful Review
I ordered saccharomyces to enhance my gastrointestinal health due to hypothyroidism and AIT, which had left my digestive system quite unbalanced. I faced constant discomfort, bloating, and thrush. Instead of buying numerous expensive enzyme and probiotic preparations, I opted for Boulardi saccharomyces. I took 2 capsules at night, and I've seen remarkable results—within days, the bloating and discomfort dissipated, and my stool normalised. Additionally, after experiencing stomach pain from hormone therapy pills, the discomfort eased within 15 minutes post-saccharomycetes intake. It's a definite favourite, and more affordable than pharmacy alternatives!
L Taurine
9
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
9.5
Increased energy levels
Most Useful Review
Really Works! I was pleasantly surprised at the effects, feeling a difference by the second day of taking it. My energy levels increased dramatically, and I felt revitalised! This is absolute happiness! My hypothyroidism seems more manageable now.
Enzymes
7
We explored the effects of a combination of magnesium, selenium, and coenzyme Q10 on the thyroid morphology in patients suffering from benign thyroid diseases, specifically looking at both hyperthyroidism and hypothyroidism. Our study involved 8 patients who received standard pharmacological treatment but also underwent additional therapy at our private institution.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
9.5
Supports thyroid recovery
Most Useful Review
I have bought this product multiple times for heart health. My husband has taken it for over five years, witnessing substantial improvement in his heart condition. I started it this year for my hypothyroidism and hyperlipidemia, and it appears to aid in restoring thyroid function while protecting cardiovascular health.
B12
7
We explored the protective role of brewer's yeast in combating the harmful effects of methimazole-induced hypothyroidism. In a study involving 48 rats, we divided them into control and experimental groups to assess the impact of methimazole and brewer's yeast on adrenal glands.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
9.5
Essential for energy
Most Useful Review
Excellent! Vitamin B12 is indispensable for the body. It boosts haemoglobin, benefits heart muscle, aids in DNA synthesis, and supports energy production. As many of us suffer from anaemia, B12 is vital. I take at least 1000 mcg in methylated sublingual form, which is absorbed immediately. Living with hypothyroidism, it is essential for me, and I consume it regularly with meals, avoiding other vitamins.
5 Htp
4
5-HTP shows limited benefit
We observed a study focusing on the effects of 5-hydroxytryptophan (5-HTP) in rats with hypothyroidism. The research involved male rats that were born to mothers on an iodide-free diet and later treated with methimazole, rendering them hypothyroid.
After the treatment concluded, both euthyroid (normal thyroid function) and hypothyroid rats received an injection of 5-HTP. What we discovered was that the behavioral reactions in hypothyroid rats were significantly milder compared to their euthyroid counterparts. This finding suggests that hypothyroidism may lead to decreased central serotonin function, resulting in reduced serotonergic activity.
While the study provides insight into the behavior of hypothyroid rats in response to 5-HTP, it indicates that treatment might not bring significant improvement in serotonin activity for those with hypothyroidism. Thus, while there is some behavioral impact observed, the extent of benefit from 5-HTP in treating hypothyroidism appears limited.
After the treatment concluded, both euthyroid (normal thyroid function) and hypothyroid rats received an injection of 5-HTP. What we discovered was that the behavioral reactions in hypothyroid rats were significantly milder compared to their euthyroid counterparts. This finding suggests that hypothyroidism may lead to decreased central serotonin function, resulting in reduced serotonergic activity.
While the study provides insight into the behavior of hypothyroid rats in response to 5-HTP, it indicates that treatment might not bring significant improvement in serotonin activity for those with hypothyroidism. Thus, while there is some behavioral impact observed, the extent of benefit from 5-HTP in treating hypothyroidism appears limited.
9.5
Better sleep quality
Most Useful Review
Finally, I sleep and feel refreshed. I had nearly forgotten what restful sleep felt like. With my hypothyroidism, the anticipation of getting enough sleep was often heavy on my mind. A week after starting treatment, I noticed positive changes; I fall asleep easier, feeling completely relaxed. I wake up feeling energetic and my appetite has decreased. Losing weight with hypothyroidism is tough, but I have begun to reach my weight goals.
Multivitamins
10
Restored thyroid levels
Most Useful Review
Back in the game! After being diagnosed with hypothyroidism and taking levothyroxine for a year and a half, I felt worse daily, suffering from heart palpitations and extreme anxiety. I suspected the medication early on and stopped it after three months, but my thyroxine levels dropped, so I resumed taking it. Thankfully, after some research and my sister's recommendation to try Gaia Adrenal Health and Gaia Thyroid Support, I stopped the levothyroxine. Now, six months later, I feel fantastic, and to my doctor's surprise, my thyroid levels are normal! No more levothyroxine for me, ever!!
9.5
Miraculous stress relief
Most Useful Review
Excellent product for managing stress and hypothyroidism. I've been taking one capsule daily with breakfast for the past week, and I've noticed a difference straight away: I feel more energetic throughout the day and have no stress at all and sleep better at night. It's a miraculous supplement for me, and I plan to continue using it for the rest of my life.
Iron
9.5
Improved energy
Most Useful Review
Super supplement! I've suffered from iron deficiency and hypothyroidism for years. Nothing helped until I tried this chelated iron. It greatly improved my condition, eliminating dizziness and fatigue. I take it regularly and will continue to monitor my ferritin levels. Overall, it’s a fantastic product for managing my iron levels.
9.5
Significant improvement
Most Useful Review
After struggling with anaemia for many years, I finally discovered my hemoglobin was 80 when it should be 120. I had attributed my weakness and hair loss to my mild hypothyroidism. Since taking Solgar iron supplements for 2.5 months, my hemoglobin has risen to 122, which is normal. My overall well-being has greatly improved, and my hair hardly falls out anymore. Although my ferritin levels are still low, I understand that it takes about six months of iron preparation to raise them. I am VERY SATISFIED.
Spirulina
8.8
Reduced hair loss
Most Useful Review
Since I have hypothyroidism, I experienced significant hair loss. However, after just two weeks of taking Spirulina, my hair loss has decreased by a third. I found that I was eating less, had less craving for sweets, and felt more energetic. I will definitely order more tablets as I experienced no nausea or side effects.
8.8
Improved wellbeing
Most Useful Review
SPIRULINA is an excellent choice if you want your body to express gratitude! This remarkable seaweed is packed with vitamins and minerals. Its nutrients boost the immune system, enhance digestion, and improve the function of the thyroid gland, making it highly beneficial for hypothyroidism. Personally, I take Spirulina twice daily and feel a constant surge of energy. It's a fabulous addition to my health routine!
Ubiquinol Coq10
8.8
Improves energy levels
Most Useful Review
I take this alongside Omega-3 and CLA to enhance my metabolism and energy levels, as I tend to tire easily due to chronic hypothyroidism. Ubiquinol is also advised for kidney and vascular diseases. I feel better on this supplement. I take it after meals, and the gel capsules are easy to swallow, without causing any side effects.
9.5
Increases strength
Most Useful Review
I have completely lost my thyroid gland due to hypothyroidism. For two years, I’ve taken ubiquinol with omega daily. It provides me with strength and energy, even during fasting. Many of my friends now take it. It’s an essential supplement for memory and brain function, replacing my previous medications, and I always stock up on it.
Fiber
8.8
Effective treatment
Most Useful Review
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.
8.8
Increased energy levels
Most Useful Review
I switched to a simpler iodine with vitamin K and appreciate the capsule size, which is easy to swallow. The vegetable iodine dosage is high, but not fully absorbed due to my hypothyroidism. My endocrinologist approved its use, and I take it alongside selenium for better absorption. After three months, I feel increased energy and recommend it.