Overview
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.1
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
13 mcg (500 IU)
63%
Calcium (as Calcium Citrate)
630 mg
48%
Top Medical Research Studies
1
We set out to explore the impact of calcium and vitamin D supplements on menopause-related symptoms among postmenopausal women. In the Women's Health Initiative Calcium/Vitamin D Trial, over 34,000 women participated, receiving either the supplements or a placebo over an average of 5.7 years.
Our results revealed that women taking the calcium and vitamin D supplements experienced no significant differences in menopause symptoms, including sleep disturbances and emotional well-being, compared to those on the placebo. This suggests that the combination does not have the expected benefits for managing menopause symptoms.
Our results revealed that women taking the calcium and vitamin D supplements experienced no significant differences in menopause symptoms, including sleep disturbances and emotional well-being, compared to those on the placebo. This suggests that the combination does not have the expected benefits for managing menopause symptoms.
Read More
4
We conducted a controlled study to understand how calcium and vitamin D3 supplements affect healthy, early postmenopausal women who already had sufficient calcium and vitamin D levels.
Sixteen women participated in our three-week trial, where they took either calcium, calcium plus vitamin D3, or a placebo. While calcium intake did increase urinary calcium excretion in the calcium group, the addition of vitamin D3 did not provide significant extra benefits.
Ultimately, the findings suggest that these supplements have only minor and uncertain effects on calcium balance in those already adequately provided with these nutrients.
Sixteen women participated in our three-week trial, where they took either calcium, calcium plus vitamin D3, or a placebo. While calcium intake did increase urinary calcium excretion in the calcium group, the addition of vitamin D3 did not provide significant extra benefits.
Ultimately, the findings suggest that these supplements have only minor and uncertain effects on calcium balance in those already adequately provided with these nutrients.
Read More
7
Calcium aids bone density, not fractures
We examined how calcium supplements impact bone mineral density and fracture risk among women transitioning through menopause. Our analysis included a diverse group of nearly 1,500 women followed for over a decade.
We found that while calcium supplementation helped reduce the annual loss of bone density, particularly in premenopausal women, it did not decrease the risk of fractures. This suggests that while calcium may support bone health, it doesn't necessarily protect against fractures during menopause.
We found that while calcium supplementation helped reduce the annual loss of bone density, particularly in premenopausal women, it did not decrease the risk of fractures. This suggests that while calcium may support bone health, it doesn't necessarily protect against fractures during menopause.
Read More
Most Useful Reviews
9
Improved health benefits
4 people found this helpful
Gorgeous calcium. My family and I take 2 capsules daily along with vitamin K2, ensuring calcium reaches our bones and teeth rather than soft tissues. Since starting, our nails have improved, and my teeth no longer react to sweets or temperature. I found this helpful, especially during menopause.
Read More
7.5
Pain relief
4 people found this helpful
I began taking calcium on my endocrinologist's advice to support my bones during menopause, which can cause thinning and vulnerabilities. Since starting, my joint pain has diminished, and I feel more energetic. The citrate form is well absorbed. I highly recommend it.
Read More
9
Effective treatment
2 people found this helpful
This calcium preparation is excellent, as it helps without upsetting my stomach. I have experienced terrible bone pain with early menopause, but since switching to this digestible form, my cramps have ceased, and bone pain has lessened. I wholeheartedly recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.1
- All Researches
9
Calcium absorption improved with treatment
We investigated how combining alendronate with vitamin D affects calcium absorption in postmenopausal women with low bone density. This clinical trial involved 56 women and used a double-blind, placebo-controlled design.
After one month, those receiving the treatment showed a significant increase in calcium absorption, while the placebo group saw no notable change. Additionally, participants on the treatment experienced improved vitamin D levels.
While the findings are promising for managing osteoporosis, more research is needed to understand the precise mechanisms behind these effects.
After one month, those receiving the treatment showed a significant increase in calcium absorption, while the placebo group saw no notable change. Additionally, participants on the treatment experienced improved vitamin D levels.
While the findings are promising for managing osteoporosis, more research is needed to understand the precise mechanisms behind these effects.
Read More
8
We conducted an observational study to explore how a combination of calcium, vitamin D3, soy isoflavones, and inulin might reduce hot flushes in post-menopausal women.
Involving 135 participants, we found that those taking the supplement experienced a notable decrease in hot flushes compared to those who weren't treated.
Specifically, after six months, women in the supplement group reported an average reduction of about 3.7 hot flushes, while the untreated group showed significantly less improvement.
This suggests that calcium and vitamin D, along with other dietary components, could be helpful in managing menopausal symptoms.
Involving 135 participants, we found that those taking the supplement experienced a notable decrease in hot flushes compared to those who weren't treated.
Specifically, after six months, women in the supplement group reported an average reduction of about 3.7 hot flushes, while the untreated group showed significantly less improvement.
This suggests that calcium and vitamin D, along with other dietary components, could be helpful in managing menopausal symptoms.
Read More
8
Calcium, Vitamin D, and Fractures
We examined how calcium and vitamin D treatment affects bone health in older adults. Research shows that elderly individuals lose bone mass at a steady rate, increasing their fracture risk. While calcium supplementation shows promise in slowing bone loss, particularly in older women, its effectiveness in preventing fractures remains uncertain.
Additionally, vitamin D deficiency is common in this age group, and its supplementation can help slow bone loss, especially in winter. Overall, combining calcium and vitamin D may lower hip fracture risks for those who are frail.
Additionally, vitamin D deficiency is common in this age group, and its supplementation can help slow bone loss, especially in winter. Overall, combining calcium and vitamin D may lower hip fracture risks for those who are frail.
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8
Calcium maltobionate supports bone health
We conducted a study to investigate how calcium maltobionate affects bone density in healthy Japanese women, particularly focusing on those who are pre- and post-menopausal. In a well-structured trial, 48 women aged between 30 and 69 were randomly divided into two groups: one received calcium maltobionate tablets while the other took a placebo designed to mimic the calcium content.
Over 24 weeks, we measured changes in facial and calcaneal bone density along with bone resorption markers. Our results indicated that facial bone mineral density declines more rapidly than that of other areas like the lumbar spine. Importantly, we observed that continuous intake of calcium maltobionate helped to slow down this decline in bone density for women in both menopausal stages, suggesting its potential role in osteoporosis prevention.
Overall, we found that facial bone mineral density may serve as an important indicator of bone health in middle-aged women. While our study highlights the beneficial aspects of calcium maltobionate, it’s essential to note that the individual effects of calcium itself could not be isolated from the compound used in the treatment.
Over 24 weeks, we measured changes in facial and calcaneal bone density along with bone resorption markers. Our results indicated that facial bone mineral density declines more rapidly than that of other areas like the lumbar spine. Importantly, we observed that continuous intake of calcium maltobionate helped to slow down this decline in bone density for women in both menopausal stages, suggesting its potential role in osteoporosis prevention.
Overall, we found that facial bone mineral density may serve as an important indicator of bone health in middle-aged women. While our study highlights the beneficial aspects of calcium maltobionate, it’s essential to note that the individual effects of calcium itself could not be isolated from the compound used in the treatment.
Read More
7
Vitamin D3 and calcium reduce fractures
We examined how daily oral supplementation of vitamin D3 and calcium impacts hip fractures in those over 65. After reviewing several studies and following strict guidelines, we found that taking 800 IU of vitamin D3 alongside 1200 mg of calcium significantly reduces hip and non-vertebral fractures.
However, the treatment did not improve bone density in the femoral neck. This highlights the importance of supplements in fracture prevention while encouraging a comprehensive approach to bone health, especially during menopause.
However, the treatment did not improve bone density in the femoral neck. This highlights the importance of supplements in fracture prevention while encouraging a comprehensive approach to bone health, especially during menopause.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved health benefits
4 people found this helpful
Gorgeous calcium. My family and I take 2 capsules daily along with vitamin K2, ensuring calcium reaches our bones and teeth rather than soft tissues. Since starting, our nails have improved, and my teeth no longer react to sweets or temperature. I found this helpful, especially during menopause.
Read More
7.5
Pain relief
4 people found this helpful
I began taking calcium on my endocrinologist's advice to support my bones during menopause, which can cause thinning and vulnerabilities. Since starting, my joint pain has diminished, and I feel more energetic. The citrate form is well absorbed. I highly recommend it.
Read More
9
Effective treatment
2 people found this helpful
This calcium preparation is excellent, as it helps without upsetting my stomach. I have experienced terrible bone pain with early menopause, but since switching to this digestible form, my cramps have ceased, and bone pain has lessened. I wholeheartedly recommend it.
Read More
9
Bone health support
1 people found this helpful
I give this calcium citrate to my parents to prevent osteoporosis during menopause, and it's far superior to other products. I would appreciate a positive click on my review. Stay healthy!
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9
Supports daily intake
1 people found this helpful
I buy this calcium again as I’m over 50 and need it before menopause. It meets the daily intake and maintains my health. While the tablets are large, they’re manageable, and I’ve had no joint pain.
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Frequently Asked Questions
9
Improved well-being
Easily digestible calcium with good quality. The chelated calcium citrate is well absorbed, and I only need 2 tablets compared to others that suggest 4. The neutral taste helps with bone strength, and I noticed improvements in my joints, hair, and nails a few weeks after starting this during menopause.
7.5
Pain relief
4 people found this helpful
I began taking calcium on my endocrinologist's advice to support my bones during menopause, which can cause thinning and vulnerabilities. Since starting, my joint pain has diminished, and I feel more energetic. The citrate form is well absorbed. I highly recommend it.
9
Effective treatment
2 people found this helpful
This calcium preparation is excellent, as it helps without upsetting my stomach. I have experienced terrible bone pain with early menopause, but since switching to this digestible form, my cramps have ceased, and bone pain has lessened. I wholeheartedly recommend it.
9
Improved health benefits
4 people found this helpful
Gorgeous calcium. My family and I take 2 capsules daily along with vitamin K2, ensuring calcium reaches our bones and teeth rather than soft tissues. Since starting, our nails have improved, and my teeth no longer react to sweets or temperature. I found this helpful, especially during menopause.
6
Enhanced absorption
1 people found this helpful
This citrated calcium is better absorbed than gluconates or carbonates. It absorbs well with vitamin D3, plus phosphorus and magnesium. I find it effective, though the tablets are sizable. I notice my nails suffer without calcium, especially during menopause.
4
Calcium and vitamin D effects on bone
Our evaluation focused on how calcium combined with vitamin D influences bone health during menopause. We reviewed nine clinical trials and found that while vitamin D supplementation improved certain bone health markers, it didn’t significantly lower fracture risk for postmenopausal women without osteoporosis.
Notably, doses between 800 to 1000 IU paired with calcium showed some benefits in bone mineral density. However, higher doses didn't seem to prevent fractures. Thus, while these supplements enhanced vitamin D levels and some aspects of bone remodeling, the overall effect on fracture risk remains unclear.
Notably, doses between 800 to 1000 IU paired with calcium showed some benefits in bone mineral density. However, higher doses didn't seem to prevent fractures. Thus, while these supplements enhanced vitamin D levels and some aspects of bone remodeling, the overall effect on fracture risk remains unclear.
8
We conducted an observational study to explore how a combination of calcium, vitamin D3, soy isoflavones, and inulin might reduce hot flushes in post-menopausal women.
Involving 135 participants, we found that those taking the supplement experienced a notable decrease in hot flushes compared to those who weren't treated.
Specifically, after six months, women in the supplement group reported an average reduction of about 3.7 hot flushes, while the untreated group showed significantly less improvement.
This suggests that calcium and vitamin D, along with other dietary components, could be helpful in managing menopausal symptoms.
Involving 135 participants, we found that those taking the supplement experienced a notable decrease in hot flushes compared to those who weren't treated.
Specifically, after six months, women in the supplement group reported an average reduction of about 3.7 hot flushes, while the untreated group showed significantly less improvement.
This suggests that calcium and vitamin D, along with other dietary components, could be helpful in managing menopausal symptoms.
1
We set out to explore the impact of calcium and vitamin D supplements on menopause-related symptoms among postmenopausal women. In the Women's Health Initiative Calcium/Vitamin D Trial, over 34,000 women participated, receiving either the supplements or a placebo over an average of 5.7 years.
Our results revealed that women taking the calcium and vitamin D supplements experienced no significant differences in menopause symptoms, including sleep disturbances and emotional well-being, compared to those on the placebo. This suggests that the combination does not have the expected benefits for managing menopause symptoms.
Our results revealed that women taking the calcium and vitamin D supplements experienced no significant differences in menopause symptoms, including sleep disturbances and emotional well-being, compared to those on the placebo. This suggests that the combination does not have the expected benefits for managing menopause symptoms.
7
Vitamin D3 and calcium reduce fractures
We examined how daily oral supplementation of vitamin D3 and calcium impacts hip fractures in those over 65. After reviewing several studies and following strict guidelines, we found that taking 800 IU of vitamin D3 alongside 1200 mg of calcium significantly reduces hip and non-vertebral fractures.
However, the treatment did not improve bone density in the femoral neck. This highlights the importance of supplements in fracture prevention while encouraging a comprehensive approach to bone health, especially during menopause.
However, the treatment did not improve bone density in the femoral neck. This highlights the importance of supplements in fracture prevention while encouraging a comprehensive approach to bone health, especially during menopause.
7
Calcium aids bone density, not fractures
We examined how calcium supplements impact bone mineral density and fracture risk among women transitioning through menopause. Our analysis included a diverse group of nearly 1,500 women followed for over a decade.
We found that while calcium supplementation helped reduce the annual loss of bone density, particularly in premenopausal women, it did not decrease the risk of fractures. This suggests that while calcium may support bone health, it doesn't necessarily protect against fractures during menopause.
We found that while calcium supplementation helped reduce the annual loss of bone density, particularly in premenopausal women, it did not decrease the risk of fractures. This suggests that while calcium may support bone health, it doesn't necessarily protect against fractures during menopause.
References
- Reis AR, Santos RKF, Dos Santos CB, Santos BDC, de Carvalho GB, et al. Supplementation of vitamin D isolated or calcium-associated with bone remodeling and fracture risk in postmenopausal women without osteoporosis: A systematic review of randomized clinical trials. Nutrition. 2023;116:112151. 10.1016/j.nut.2023.112151
- Manoj P, Derwin R, George S. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis. Int J Older People Nurs. 2023;18:e12492. 10.1111/opn.12492
- Bailey RL, Zou P, Wallace TC, McCabe GP, Craig BA, et al. Calcium Supplement Use Is Associated With Less Bone Mineral Density Loss, But Does Not Lessen the Risk of Bone Fracture Across the Menopause Transition: Data From the Study of Women's Health Across the Nation. JBMR Plus. 2020;4:e10246. 10.1002/jbm4.10246
- Cianci A, Colacurci N, Paoletti AM, Perino A, Cicinelli E, et al. Soy isoflavones, inulin, calcium, and vitamin D3 in post-menopausal hot flushes: an observational study. Clin Exp Obstet Gynecol. 2015;42:743.
- LeBlanc ES, Hedlin H, Qin F, Desai M, Wactawski-Wende J, et al. Calcium and vitamin D supplementation do not influence menopause-related symptoms: Results of the Women's Health Initiative Trial. Maturitas. 2015;81:377. 10.1016/j.maturitas.2015.04.007
- Genç S, Ömer B, Aycan-Üstyol E, Kumral A, Gürdöl F. Bone turnover markers and vitamin D status in postmenopausal Turkish women. Int J Vitam Nutr Res. 2012;82:27. 10.1024/0300-9831/a000091
- Shapses SA, Kendler DL, Robson R, Hansen KE, Sherrell RM, et al. Effect of alendronate and vitamin D₃ on fractional calcium absorption in a double-blind, randomized, placebo-controlled trial in postmenopausal osteoporotic women. J Bone Miner Res. 2011;26:1836. 10.1002/jbmr.395
- Floreani A, Carderi I, Ferrara F, Rizzotto ER, Luisetto G, et al. A 4-year treatment with clodronate plus calcium and vitamin D supplements does not improve bone mass in primary biliary cirrhosis. Dig Liver Dis. 2007;39:544.
- Tfelt-Hansen J, Tørring O. Calcium and vitamin D3 supplements in calcium and vitamin D3 sufficient early postmenopausal healthy women. Eur J Clin Nutr. 2004;58:1420.
- Cummings SR. Bone mass and bone loss in the elderly: a special case?. Int J Fertil Menopausal Stud. 1993;38 Suppl 2:92.
- Atteia HH, Ahmed SF, Askar ME, Sakr AT. Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats. Biol Trace Elem Res. 2024. 10.1007/s12011-024-04476-y
- Cocetta V, Zorzi M, Bejor S, Cesta MC, De Pizzol M, et al. Retrospective Analysis of the Effect of Postmenopausal Women Medications on SARS-CoV-2 Infection Progression. Life (Basel). 2024;14. 10.3390/life14091107
- Suehiro D, Ikeda N, Hirooka K, Ihara A, Fukami K, et al. Decrease in Facial Bone Density with Aging and Maintenance Effect of Calcium Maltobionate Ingestion in Japanese Adult Women: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial. Nutrients. 2025;17. 10.3390/nu17020262
- Hou J, Mao H, Xie P, Cui Y, Rong M. The effect of different traditional Chinese exercises on bone mineral density in menopausal women: a systematic review and network meta-analysis. Front Public Health. 2024;12:1430608. 10.3389/fpubh.2024.1430608
