Last update
4/17/2026

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2) 
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%
📅 Last updated:

Top Medical Research Studies

9
Panthenol mask improves skin barrier
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.

Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.

The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.

Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More

Most Useful Reviews

7
Reduced acne symptoms
4 people found this helpful
I struggle with metabolising fat and sugar, but vitamin B has increased my appetite and reduced postprandial fatigue. My acne has decreased too. Since it's time-release, there's no need to take it multiple times a day, and I appreciate that it's affordable and easy to maintain.
Read More
8
Reduced sebum production
2 people found this helpful
A good vitamin B supplement that you can't buy in Japan. There are no supplements here with so many B vitamins. I only drink it once a day with meals. After taking this, I've noticed a decrease in sebum production from my face and body. Acne has also become less frequent, and I feel my skin has improved. I will continue to drink it.
Read More
6
Helps early healing
1 people found this helpful
I was searching for a sustained release vitamin due to my acne and canker sores. Although it has an unpleasant taste and smell, it’s effective. I only take it during breakouts, and it really helps heal the spots before they worsen. I highly recommend it.
Read More

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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Panthenol mask improves skin barrier
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.

Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.

The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.

Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 8 Reviews
7.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7
Reduced acne symptoms
4 people found this helpful
I struggle with metabolising fat and sugar, but vitamin B has increased my appetite and reduced postprandial fatigue. My acne has decreased too. Since it's time-release, there's no need to take it multiple times a day, and I appreciate that it's affordable and easy to maintain.
Read More
8
Reduced sebum production
2 people found this helpful
A good vitamin B supplement that you can't buy in Japan. There are no supplements here with so many B vitamins. I only drink it once a day with meals. After taking this, I've noticed a decrease in sebum production from my face and body. Acne has also become less frequent, and I feel my skin has improved. I will continue to drink it.
Read More
6
Helps early healing
1 people found this helpful
I was searching for a sustained release vitamin due to my acne and canker sores. Although it has an unpleasant taste and smell, it’s effective. I only take it during breakouts, and it really helps heal the spots before they worsen. I highly recommend it.
Read More
8
Affordable option
The cost performance is excellent; it's inexpensive per pill and very effective. I use it primarily for treating acne.
Read More
7
Improved skin condition
This works wonders for my skin and hair; I also take it with vitamin E and A. My skin looks healthier, less oily, and has fewer acne issues.
Read More

Frequently Asked Questions

7
Improved skin condition
This works wonders for my skin and hair; I also take it with vitamin E and A. My skin looks healthier, less oily, and has fewer acne issues.
8
Reduced sebum production
2 people found this helpful
A good vitamin B supplement that you can't buy in Japan. There are no supplements here with so many B vitamins. I only drink it once a day with meals. After taking this, I've noticed a decrease in sebum production from my face and body. Acne has also become less frequent, and I feel my skin has improved. I will continue to drink it.
7
Reduced acne symptoms
4 people found this helpful
I struggle with metabolising fat and sugar, but vitamin B has increased my appetite and reduced postprandial fatigue. My acne has decreased too. Since it's time-release, there's no need to take it multiple times a day, and I appreciate that it's affordable and easy to maintain.
9
Panthenol mask improves skin barrier
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.

Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.

The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.

References

  1. Zhang X, Tao H, Deng Y, He X, Zhang Z, et al. Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes. J Cosmet Dermatol. 2024;23:2109. 10.1111/jocd.16231
  2. Al-Sharnoby HA, Al-Bakary RH, Nassar SO, Mesbah RAM. The Efficacy of Intense Pulsed Light Versus Topical Nicotinamide 4% in Treatment of Acne Vulgaris. Photodermatol Photoimmunol Photomed. 2025;41:e70025. 10.1111/phpp.70025
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