Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
USERS' SCORE
Good
Based on 8 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%
Top Medical Research Studies
9
We explored the effectiveness of folic acid in alleviating menopausal hot flashes in a clinical trial involving 70 women. Participants were randomly assigned to receive either folic acid or a placebo for four weeks.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
Read More
8
We conducted a randomized placebo-controlled trial involving 48 healthy postmenopausal women, testing the impact of folic acid on plasma homocysteine levels—a potential risk factor for cardiovascular issues and osteoporosis. After 16-17 weeks, we observed that those taking folic acid had significantly lower homocysteine levels compared to the placebo group (10.33 μmol/l vs 13.21 μmol/l).
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
Read More
7
We aimed to explore how folic acid influences sexual function in postmenopausal women. This triple-blind randomized controlled trial, conducted in Tehran, involved 100 women receiving either a daily folic acid supplement or a placebo for eight weeks.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
Read More
Most Useful Reviews
9
Supports menopause transition
Folic Acid is very good value for money! I take it regularly! It effectively restores all mucous tissues and aids in healing women's reproductive organs. While often associated only with pregnancy, this acid is also beneficial for experiencing menopause smoothly, both during and after it! After 40, it's absolutely essential for the female body. It also plays a role in cellular metabolism and boosts metabolic rate!
Read More
7.5
Energy boost for women
Folic acid plays a crucial role in regenerating new cells and preserving old ones, boosting energy levels. Regular intake leads to fresh, smooth skin, thick shiny hair, and strong nails. It also enhances mood, particularly during PMS and menopause, positively impacting the nervous system and metabolism. The quality is high and the pill size is convenient.
Read More
9
Preserves youthfulness
Regular intake of folic acid helps women maintain their youth. This vitamin promotes new cell growth and preserves existing ones, contributing to smooth skin, thick hair, and strong nails. It also enhances mood, particularly useful during PMS and menopause when emotional sensitivity is heightened. My wife feels satisfied with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
- All Researches
9
We explored the effectiveness of folic acid in alleviating menopausal hot flashes in a clinical trial involving 70 women. Participants were randomly assigned to receive either folic acid or a placebo for four weeks.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
Read More
8
We conducted a randomized placebo-controlled trial involving 48 healthy postmenopausal women, testing the impact of folic acid on plasma homocysteine levels—a potential risk factor for cardiovascular issues and osteoporosis. After 16-17 weeks, we observed that those taking folic acid had significantly lower homocysteine levels compared to the placebo group (10.33 μmol/l vs 13.21 μmol/l).
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
Read More
7
We aimed to explore how folic acid influences sexual function in postmenopausal women. This triple-blind randomized controlled trial, conducted in Tehran, involved 100 women receiving either a daily folic acid supplement or a placebo for eight weeks.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
Read More
7
We examined how folic acid supplements impact homocysteine levels in postmenopausal women over six months. Our findings suggest that after menopause, homocysteine levels rise significantly, presenting a cardiovascular risk.
While folic acid is a safe and affordable option, our study indicates that it may help lower homocysteine, potentially offering some protection against heart disease in this group. However, more research is needed to fully understand its effectiveness.
While folic acid is a safe and affordable option, our study indicates that it may help lower homocysteine, potentially offering some protection against heart disease in this group. However, more research is needed to fully understand its effectiveness.
Read More
7
Folate impacts menopause bone density
We investigated whether folates, vitamin B12, or homocysteine levels predict changes in bone density among postmenopausal women. Over five years, we measured these factors in 161 healthy volunteers, focusing on vertebral bone mineral density (BMD).
Our findings revealed that folates were significantly associated with BMD changes, indicating that low folate levels could contribute to bone density decline. However, we found no significant link between variations in BMD and homocysteine or vitamin B12 levels.
This highlights the potential importance of folate levels in supporting bone health during menopause.
Our findings revealed that folates were significantly associated with BMD changes, indicating that low folate levels could contribute to bone density decline. However, we found no significant link between variations in BMD and homocysteine or vitamin B12 levels.
This highlights the potential importance of folate levels in supporting bone health during menopause.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports menopause transition
Folic Acid is very good value for money! I take it regularly! It effectively restores all mucous tissues and aids in healing women's reproductive organs. While often associated only with pregnancy, this acid is also beneficial for experiencing menopause smoothly, both during and after it! After 40, it's absolutely essential for the female body. It also plays a role in cellular metabolism and boosts metabolic rate!
Read More
7.5
Energy boost for women
Folic acid plays a crucial role in regenerating new cells and preserving old ones, boosting energy levels. Regular intake leads to fresh, smooth skin, thick shiny hair, and strong nails. It also enhances mood, particularly during PMS and menopause, positively impacting the nervous system and metabolism. The quality is high and the pill size is convenient.
Read More
9
Preserves youthfulness
Regular intake of folic acid helps women maintain their youth. This vitamin promotes new cell growth and preserves existing ones, contributing to smooth skin, thick hair, and strong nails. It also enhances mood, particularly useful during PMS and menopause when emotional sensitivity is heightened. My wife feels satisfied with the results.
Read More
7.5
Menopause support
Helps with menopause in combination with other supplements.
Read More
7.5
Aids recovery from menopause
Its price is low compared to the great quality it offers. I highly recommend it! My mum takes it because it helps her recover from bleeding issues caused by her menopause.
Read More
Frequently Asked Questions
9
Preserves youthfulness
Regular intake of folic acid helps women maintain their youth. This vitamin promotes new cell growth and preserves existing ones, contributing to smooth skin, thick hair, and strong nails. It also enhances mood, particularly useful during PMS and menopause when emotional sensitivity is heightened. My wife feels satisfied with the results.
7.5
Improves skin condition
1 people found this helpful
Folic acid is vital for our health. But why do we need it? It enhances immunity, supports heart and blood vessel function, and aids in blood cell formation, particularly with iron deficiency. For women, it’s an essential vitamin: it regenerates new cells and preserves old ones, keeping skin fresh and smooth, while making hair thick and shiny, and nails strong. Regular intake improves mood, notably helping with PMS and menopause.
7.5
Aids recovery from menopause
Its price is low compared to the great quality it offers. I highly recommend it! My mum takes it because it helps her recover from bleeding issues caused by her menopause.
7.5
Energy boost for women
Folic acid plays a crucial role in regenerating new cells and preserving old ones, boosting energy levels. Regular intake leads to fresh, smooth skin, thick shiny hair, and strong nails. It also enhances mood, particularly during PMS and menopause, positively impacting the nervous system and metabolism. The quality is high and the pill size is convenient.
9
Supports menopause transition
Folic Acid is very good value for money! I take it regularly! It effectively restores all mucous tissues and aids in healing women's reproductive organs. While often associated only with pregnancy, this acid is also beneficial for experiencing menopause smoothly, both during and after it! After 40, it's absolutely essential for the female body. It also plays a role in cellular metabolism and boosts metabolic rate!
7.5
Menopause support
Helps with menopause in combination with other supplements.
9
We explored the effectiveness of folic acid in alleviating menopausal hot flashes in a clinical trial involving 70 women. Participants were randomly assigned to receive either folic acid or a placebo for four weeks.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
Our findings showed that folic acid significantly reduced the severity, duration, and frequency of hot flashes compared to the placebo. With these positive results, folic acid emerges as an affordable and accessible alternative treatment for managing menopausal symptoms.
7
We aimed to explore how folic acid influences sexual function in postmenopausal women. This triple-blind randomized controlled trial, conducted in Tehran, involved 100 women receiving either a daily folic acid supplement or a placebo for eight weeks.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
While results indicated that folic acid may positively affect sexual function according to the Female Sexual Function Index, the small sample size and short duration mean we should interpret these findings with caution. More extensive studies are necessary to validate these promising initial results.
8
We conducted a randomized placebo-controlled trial involving 48 healthy postmenopausal women, testing the impact of folic acid on plasma homocysteine levels—a potential risk factor for cardiovascular issues and osteoporosis. After 16-17 weeks, we observed that those taking folic acid had significantly lower homocysteine levels compared to the placebo group (10.33 μmol/l vs 13.21 μmol/l).
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
However, we found no significant correlations between homocysteine levels and factors like BMI and parity, though slight correlations with age and duration of menopause were noted. This suggests folic acid may help manage homocysteine, beneficial for heart health and bone density after menopause.
4
We conducted a phase III double-blind, placebo-controlled trial to assess the effects of folic acid supplementation on hot flushes in postmenopausal women. This study, which took place across nine hospitals in England, involved 164 women who reported experiencing at least 50 hot flushes each week. Participants were randomly assigned to take either a daily 5 mg folic acid tablet or a placebo for 12 weeks.
Throughout this period, we asked participants to document the frequency and severity of their hot flushes using a Sloan Diary, along with answering questions from validated quality of life scales at regular intervals. When we analyzed the data, we found that while women taking folic acid experienced a mean reduction in their Hot Flush Score, this decrease was not statistically significant compared to those on placebo.
Specifically, the difference in improvement between the folic acid group and the placebo group was marginal, indicating no clear advantage of folic acid in alleviating hot flushes over the study duration. However, some enhancements were noted in emotional and overall quality of life scores among the folic acid group at week 8, suggesting potential benefits that may require further exploration.
Ultimately, this study did not establish folic acid as a proven treatment for reducing hot flushes in postmenopausal women, highlighting the need for more comprehensive research to confirm its effects.
Throughout this period, we asked participants to document the frequency and severity of their hot flushes using a Sloan Diary, along with answering questions from validated quality of life scales at regular intervals. When we analyzed the data, we found that while women taking folic acid experienced a mean reduction in their Hot Flush Score, this decrease was not statistically significant compared to those on placebo.
Specifically, the difference in improvement between the folic acid group and the placebo group was marginal, indicating no clear advantage of folic acid in alleviating hot flushes over the study duration. However, some enhancements were noted in emotional and overall quality of life scores among the folic acid group at week 8, suggesting potential benefits that may require further exploration.
Ultimately, this study did not establish folic acid as a proven treatment for reducing hot flushes in postmenopausal women, highlighting the need for more comprehensive research to confirm its effects.
7
We explored how folic acid might affect cardiovascular health during menopause, particularly concerning high levels of homocysteine, which can damage blood vessels. The study reviewed existing literature and found that folic acid supplementation is effective in reducing these high homocysteine levels. Additionally, it was noted that folate could improve endothelial function, helping to protect postmenopausal women from heart-related issues. This suggests that incorporating folic acid could be beneficial for cardiovascular health during and after menopause.
References
- Asadi M, Riazi H, Abbasinazari M, Majd HA, Montazeri A. Effect of folic acid on the sexual function of postmenopausal women: a triple-blind randomized controlled trial. J Sex Med. 2023;20:1180. 10.1093/jsxmed/qdad086
- Almassinokiani F, Kashanian M, Akbari P, Mossayebi E, Sadeghian E. Folic acid supplementation reduces plasma homocysteine in postmenopausal women. J Obstet Gynaecol. 2016;36:492. 10.3109/01443615.2015.1091811
- Bani S, Hasanpour S, Farzad Rik L, Hasankhani H, Sharami SH. The effect of folic Acid on menopausal hot flashes: a randomized clinical trial. J Caring Sci. 2013;2:131. 10.5681/jcs.2013.016
- Sultan N, Khan MA, Malik S. Effect of folic acid supplementation on homocysteine level in postmenopausal women. J Ayub Med Coll Abbottabad. 2007;19:78.
- Cagnacci A, Bagni B, Zini A, Cannoletta M, Generali M, et al. Relation of folates, vitamin B12 and homocysteine to vertebral bone mineral density change in postmenopausal women. A five-year longitudinal evaluation. Bone. 2008;42:314. 10.1016/j.bone.2007.10.022
- Rejnmark L, Vestergaard P, Hermann AP, Brot C, Eiken P, et al. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women. Calcif Tissue Int. 2008;82:1. 10.1007/s00223-007-9087-0
- Villa P, Suriano R, Costantini B, Macrì F, Ricciardi L, et al. Hyperhomocysteinemia and cardiovascular risk in postmenopausal women: the role of folate supplementation. Clin Chem Lab Med. 2007;45:130.
- Vázquez-Lorente H, Herrera-Quintana L, Molina-López J, Gamarra Y, Planells E. Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B, and folate in a postmenopausal population. J Trace Elem Med Biol. 2022;71:126942. 10.1016/j.jtemb.2022.126942
- Ewies A, Ahmed I, Al-Azzawi F, Pitkin J, Gupta P, et al. Folic acid supplementation in postmenopausal women with hot flushes: phase III randomised double-blind placebo-controlled trial. BJOG. 2021;128:2024. 10.1111/1471-0528.16739
