Last update
3/18/2026
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Infographics
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 38 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
Top Medical Research Studies
9
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More
9
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.
We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.
However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.
However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More
Most Useful Reviews
10
Effective for acne
189 people found this helpful
I'm amazed! After years of battling acne linked to sugar and hormones, I discovered that liver health affects skin. I began taking milk thistle, which lowered my blood sugar and supported my liver. Within a week, my skin improved immensely and I could enjoy sweets without suffering breakouts.
Read More
8
Mood and skin
102 people found this helpful
This vitamin has greatly improved my mood and energy, alongside clearing some acne. I appreciate its ease of integration into my routine without interference with other supplements. I'm thoroughly pleased with the improvements it has made.
Read More
7
Bile and acne
102 people found this helpful
Milk thistle has been beneficial for my acne as I've understood that bile stagnation contributes to my skin issues. After three cans of silymarin, I noticed my acne disappearing and my bile flow improving. I take it every six months as a preventative measure.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.
We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.
However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.
However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More
9
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More
User Reviews
USERS' SCORE
Good
Based on 38 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
Effective for acne
189 people found this helpful
I'm amazed! After years of battling acne linked to sugar and hormones, I discovered that liver health affects skin. I began taking milk thistle, which lowered my blood sugar and supported my liver. Within a week, my skin improved immensely and I could enjoy sweets without suffering breakouts.
Read More
8
Mood and skin
102 people found this helpful
This vitamin has greatly improved my mood and energy, alongside clearing some acne. I appreciate its ease of integration into my routine without interference with other supplements. I'm thoroughly pleased with the improvements it has made.
Read More
7
Bile and acne
102 people found this helpful
Milk thistle has been beneficial for my acne as I've understood that bile stagnation contributes to my skin issues. After three cans of silymarin, I noticed my acne disappearing and my bile flow improving. I take it every six months as a preventative measure.
Read More
10
Transformed skin
100 people found this helpful
After struggling with acne for a decade, I've finally discovered a solution with Silymarin. Despite not living healthily, this supplement has cleansed my liver, leading to significant skin improvements. Now I can enjoy foods without worrying about breakouts. I'm thrilled with the transformation!
Read More
6
Acne cleansed by usage
95 people found this helpful
Caution is necessary! Silymarin has helped support my liver, though I experienced acne as a result of using it. After a couple of weeks, my skin improved significantly without causing further issues.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Bageorgou F, Li L, Beausillon C, Stennevin A, Ortiz-Brugués A, et al. Tolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study. J Cosmet Dermatol. 2023;22:2259. 10.1111/jocd.15705
- Saurat JH, Reygagne P, Josse G, Hamidou Z, Bianovici S, et al. Long-Term Use of Contributes to Homeostasis in Acne-Prone Skin-A 12-Month Follow-Up International "Real Life" Cohort Study. J Pers Med. 2022;13. 10.3390/jpm13010096
- Fontao F, von Engelbrechten M, Seilaz C, Sorg O, Saurat JH. Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention. J Eur Acad Dermatol Venereol. 2020;34:357. 10.1111/jdv.15926
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