Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Pantothenic Acid (Vitamin B-5) (From Calcium Pantothenate)
500 mg
10,000%
Calcium (From Calcium Pantothenate)
45 mg
3%
Top Medical Research Studies
8
We investigated how extracts from light, medium, and dark roasted coffee beans affect contractions in the ileum, which is part of the intestine. The aim was to see if these coffee extracts could help manage gastrointestinal motility disorders like diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
Read More
Most Useful Reviews
6
Cleared cystic acne
This has nearly cleared my cystic acne, which I'm very grateful for. To achieve this, I continue taking high dosages—12 tablets in the morning and 12 at night—starting the first week with 6 in the morning and 6 at night. While it effectively clears my skin, I initially experienced mild diarrhea as a side effect. The potency is impressive, and it also supports my nervous system.
Read More
0
No effect noted
Has no effect. It doesn't seem to work at all, and I experienced a lot of diarrhea. I plan not to use it in the future, as I believe it's better to take Vitamin B Complex. The quantity of 250 capsules is excessive, and I doubt I can consume them all over an extended period.
Read More
2
Slight improvement observed
1 people found this helpful
I used it based on recommendations for improving acne through vitamin consumption. Unfortunately, it caused diarrhea and unpleasant digestive symptoms. However, it's crucial to remember that reactions can differ among individuals. After about a month of use, I did notice a slight improvement in my acne.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We investigated how extracts from light, medium, and dark roasted coffee beans affect contractions in the ileum, which is part of the intestine. The aim was to see if these coffee extracts could help manage gastrointestinal motility disorders like diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.9
- All Reviews
- Positive Reviews
- Negative Reviews
6
Cleared cystic acne
This has nearly cleared my cystic acne, which I'm very grateful for. To achieve this, I continue taking high dosages—12 tablets in the morning and 12 at night—starting the first week with 6 in the morning and 6 at night. While it effectively clears my skin, I initially experienced mild diarrhea as a side effect. The potency is impressive, and it also supports my nervous system.
Read More
0
No effect noted
Has no effect. It doesn't seem to work at all, and I experienced a lot of diarrhea. I plan not to use it in the future, as I believe it's better to take Vitamin B Complex. The quantity of 250 capsules is excessive, and I doubt I can consume them all over an extended period.
Read More
2
Slight improvement observed
1 people found this helpful
I used it based on recommendations for improving acne through vitamin consumption. Unfortunately, it caused diarrhea and unpleasant digestive symptoms. However, it's crucial to remember that reactions can differ among individuals. After about a month of use, I did notice a slight improvement in my acne.
Read More
4
Diarrhea in mega doses
1 people found this helpful
I can't feel any effect. I took it to reduce sebum oil, but taking 3 or 4 mega dose tablets results in diarrhea. If I consume fewer tablets, I do not experience diarrhea.
Read More
Frequently Asked Questions
6
Cleared cystic acne
This has nearly cleared my cystic acne, which I'm very grateful for. To achieve this, I continue taking high dosages—12 tablets in the morning and 12 at night—starting the first week with 6 in the morning and 6 at night. While it effectively clears my skin, I initially experienced mild diarrhea as a side effect. The potency is impressive, and it also supports my nervous system.
2
Slight improvement observed
1 people found this helpful
I used it based on recommendations for improving acne through vitamin consumption. Unfortunately, it caused diarrhea and unpleasant digestive symptoms. However, it's crucial to remember that reactions can differ among individuals. After about a month of use, I did notice a slight improvement in my acne.
0
No effect noted
Has no effect. It doesn't seem to work at all, and I experienced a lot of diarrhea. I plan not to use it in the future, as I believe it's better to take Vitamin B Complex. The quantity of 250 capsules is excessive, and I doubt I can consume them all over an extended period.
4
Diarrhea in mega doses
1 people found this helpful
I can't feel any effect. I took it to reduce sebum oil, but taking 3 or 4 mega dose tablets results in diarrhea. If I consume fewer tablets, I do not experience diarrhea.
8
We investigated how extracts from light, medium, and dark roasted coffee beans affect contractions in the ileum, which is part of the intestine. The aim was to see if these coffee extracts could help manage gastrointestinal motility disorders like diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
References
- Duangjai A, Rawangkan A, Yosboonruang A, Ontawong A, Saokaew S, et al. Antispasmodic Activity of Light-Roasted Coffee Extract and Its Potential Use in Gastrointestinal Motility Disorders. Foods. 2024;13. 10.3390/foods13152307
