Mizolastine and proteoglycan effectiveEffects of combination of mizolastine and proteoglycan on chronic urticaria: a randomized controlled trial.
We set out to understand how a combination of mizolastine and proteoglycan affects chronic urticaria, a condition often marked by itchy hives. In our study, we divided participants into two groups: one receiving a combination treatment that included mizolastine and proteoglycan, while the other group was treated with a similar regimen minus proteoglycan.
Over the course of four weeks, those in the treatment group experienced a significant drop in their symptoms, with 44 out of 56 showing a decline of 60% or more on the symptoms decline index. Notably, this group also had a lower relapse rate over the following two months compared to the control group.
Although calcium gluconate was part of the treatment, we found it challenging to isolate its direct impact on the improvement of hives since other factors were at play in the combined treatment approach. Overall, the results suggest that while calcium was included in the regimen, it was the combination of mizolastine and proteoglycan that primarily led to the observed improvements.
Read More
Calcium's role in hives unclearMembrane-filtration based plasma exchanges for atypical hemolytic uremic syndrome: Audit of efficacy and safety.
We assessed the effects of calcium treatment in a study focused on plasma exchanges for patients with atypical hemolytic uremic syndrome (aHUS). While the research primarily investigated the safety and efficacy of a plasma exchange, calcium was used during the procedure to prevent complications.
Interestingly, we found that administering intravenous calcium gluconate was associated with a lower incidence of certain adverse events during plasma exchange. However, the specific impact on hives or skin reactions was not directly analyzed within the study.
Overall, the findings suggest that while calcium treatment shows some protective effects during plasma exchanges, it did not provide conclusive evidence about its effectiveness against hives. Thus, we cannot definitively state that calcium effectively addresses hive-related issues in this context.
Read More