Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (from 405 mg Zinc Gluconate)
50 mg
455%
Top Medical Research Studies
8
We explored the effects of zinc on sleep by looking at how it might help with insomnia. In our study, we gave mice a zinc-containing yeast extract and monitored their behavior and brain activity. The results were quite promising.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
Read More
9
We conducted a double-blind, placebo-controlled study in a long-term care facility in Italy to assess whether nightly supplementation of melatonin, magnesium, and zinc could help improve primary insomnia in elderly residents. A total of 43 participants, mostly in their late 70s, were divided into two groups: one received a combination of these supplements, while the other received a placebo for eight weeks.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
Read More
8
We tested the effectiveness of a unique nutraceutical product, ElleN®, aimed at alleviating postmenopausal symptoms, particularly sleeplessness due to anxiety and hot flushes. This product contains several natural ingredients, including zinc, but we acknowledge that its effects are evaluated in combination with others. In our study, women experiencing mild to moderate/severe menopausal symptoms took one tablet daily for three months.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
Read More
Most Useful Reviews
7.5
Sleepiness at night
5 people found this helpful
For the last few years, I have grappled with insomnia. I tried numerous supplements, exercises, and changes to my sleeping environment, all with little success. Since starting zinc, however, I've noticed that I'm feeling unusually sleepy at night. It's early days yet, but I've been taking it for a week now, and I’m hopeful it might be providing the relief I need.
Read More
0
Negative side effects
3 people found this helpful
Unfortunately, zinc didn't work for me. After taking it for a week, I experienced strong heart palpitations, insomnia, and dizziness. When I got my levels checked, they showed high zinc, which prompted me to stop immediately. My advice is to be cautious and ensure you do thorough testing before starting any supplements, as they may not suit everyone.
Read More
0
Nausea and insomnia
Upon taking zinc, I began to experience nausea, even when I took it after meals. I would recommend starting at a lower dosage than 50mg, as that felt too strong for me. It also caused insomnia and disrupted my sleep quality. While it may be a good value for money, I won’t be repurchasing due to the side effects I encountered.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We conducted a double-blind, placebo-controlled study in a long-term care facility in Italy to assess whether nightly supplementation of melatonin, magnesium, and zinc could help improve primary insomnia in elderly residents. A total of 43 participants, mostly in their late 70s, were divided into two groups: one received a combination of these supplements, while the other received a placebo for eight weeks.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
Read More
8
We tested the effectiveness of a unique nutraceutical product, ElleN®, aimed at alleviating postmenopausal symptoms, particularly sleeplessness due to anxiety and hot flushes. This product contains several natural ingredients, including zinc, but we acknowledge that its effects are evaluated in combination with others. In our study, women experiencing mild to moderate/severe menopausal symptoms took one tablet daily for three months.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
Read More
8
We explored the effects of zinc on sleep by looking at how it might help with insomnia. In our study, we gave mice a zinc-containing yeast extract and monitored their behavior and brain activity. The results were quite promising.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Sleepiness at night
5 people found this helpful
For the last few years, I have grappled with insomnia. I tried numerous supplements, exercises, and changes to my sleeping environment, all with little success. Since starting zinc, however, I've noticed that I'm feeling unusually sleepy at night. It's early days yet, but I've been taking it for a week now, and I’m hopeful it might be providing the relief I need.
Read More
0
Negative side effects
3 people found this helpful
Unfortunately, zinc didn't work for me. After taking it for a week, I experienced strong heart palpitations, insomnia, and dizziness. When I got my levels checked, they showed high zinc, which prompted me to stop immediately. My advice is to be cautious and ensure you do thorough testing before starting any supplements, as they may not suit everyone.
Read More
0
Nausea and insomnia
Upon taking zinc, I began to experience nausea, even when I took it after meals. I would recommend starting at a lower dosage than 50mg, as that felt too strong for me. It also caused insomnia and disrupted my sleep quality. While it may be a good value for money, I won’t be repurchasing due to the side effects I encountered.
Read More
Frequently Asked Questions
7.5
Sleepiness at night
5 people found this helpful
For the last few years, I have grappled with insomnia. I tried numerous supplements, exercises, and changes to my sleeping environment, all with little success. Since starting zinc, however, I've noticed that I'm feeling unusually sleepy at night. It's early days yet, but I've been taking it for a week now, and I’m hopeful it might be providing the relief I need.
0
Negative side effects
3 people found this helpful
Unfortunately, zinc didn't work for me. After taking it for a week, I experienced strong heart palpitations, insomnia, and dizziness. When I got my levels checked, they showed high zinc, which prompted me to stop immediately. My advice is to be cautious and ensure you do thorough testing before starting any supplements, as they may not suit everyone.
0
Nausea and insomnia
Upon taking zinc, I began to experience nausea, even when I took it after meals. I would recommend starting at a lower dosage than 50mg, as that felt too strong for me. It also caused insomnia and disrupted my sleep quality. While it may be a good value for money, I won’t be repurchasing due to the side effects I encountered.
8
We explored the effects of zinc on sleep by looking at how it might help with insomnia. In our study, we gave mice a zinc-containing yeast extract and monitored their behavior and brain activity. The results were quite promising.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
9
We conducted a double-blind, placebo-controlled study in a long-term care facility in Italy to assess whether nightly supplementation of melatonin, magnesium, and zinc could help improve primary insomnia in elderly residents. A total of 43 participants, mostly in their late 70s, were divided into two groups: one received a combination of these supplements, while the other received a placebo for eight weeks.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
Throughout the study, we focused on measuring sleep quality using several tools, including the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale. After two months, we found that the group taking melatonin, magnesium, and zinc showed improvements in sleep quality and overall quality of life compared to the placebo group.
While the results are promising for the combination of these supplements, it's important to note that this study makes it challenging to determine the specific role that zinc alone may play in addressing insomnia. Nonetheless, the findings suggest that this combination could be beneficial for sleep in long-term care residents experiencing primary insomnia.
8
We tested the effectiveness of a unique nutraceutical product, ElleN®, aimed at alleviating postmenopausal symptoms, particularly sleeplessness due to anxiety and hot flushes. This product contains several natural ingredients, including zinc, but we acknowledge that its effects are evaluated in combination with others. In our study, women experiencing mild to moderate/severe menopausal symptoms took one tablet daily for three months.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
Notably, we observed a significant reduction in the Kupperman Index, an indicator of menopausal discomfort, particularly related to insomnia and anxiety linked with hot flushes. While the product was well-tolerated and didn't lead to any side effects, we are unable to specify the isolated effects of zinc because the benefits were observed in conjunction with other ingredients.
Overall, the findings suggest that natural supplements like ElleN® can be beneficial for managing menopausal symptoms without resorting to hormone replacement therapy, but we must be cautious in attributing the outcomes to zinc alone, given the combination with other components.
References
- Cappelli V, Morgante G, Di Sabatino A, Massaro MG, De Leo V. [Evaluation of the efficacy of a new nutraceutical product in the treatment of postmenopausal symptoms]. Minerva Ginecol. 2015;67:515.
- Cherasse Y, Saito H, Nagata N, Aritake K, Lazarus M, et al. Zinc-containing yeast extract promotes nonrapid eye movement sleep in mice. Mol Nutr Food Res. 2015;59:2087. 10.1002/mnfr.201500082
- Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. 10.1111/j.1532-5415.2010.03232.x
