Last update
4/4/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
Top Medical Research Studies
9.5
We evaluated the effects of Silybum marianum, a herbal remedy, on menopausal symptoms, particularly hot flashes. In a well-structured study with eighty women, half were given S. marianum extract while the other half received a placebo over 12 weeks.
Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.
This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.
This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Read More
8
Silymarin shows promise for osteoporosis
We delved into the potential effects of silymarin, derived from milk thistle, on osteoporosis, which is particularly concerning for postmenopausal women. The study highlighted how silymarin could promote bone formation and aid in fracture healing by demonstrating antioxidant properties.
In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
Read More
4
We investigated the effects of naturopathic botanical supplements, including silybum marianum, and dietary changes on hormone levels in premenopausal women over five menstrual cycles.
The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.
While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.
Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.
While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.
Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
Read More
Most Useful Reviews
9
Post-menopause refreshment
2 people found this helpful
Excellent! During menopause, I noticed my liver function declined. Drinking this before bed has me feeling refreshed in the mornings. I would like to continue using it for a while longer.
Read More
7.5
Symptoms improvement
1 people found this helpful
My liver function worsened during menopause, with elevated values. After six months on this product, I’ve noticed slight improvement. I’ll continue using it to see further effects.
Read More
7.5
Improved energy
52 people found this helpful
Effective ants for dullness! I realised that my liver was burdened while approaching menopause. I used to rely on energy drinks but now I can move when I find it hard! I’ve been drinking a combination of products, but this one is more reasonable and effective. If you are a middle-aged person feeling tired and dull, you should definitely try this. I’m grateful to have discovered it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
- All Researches
9.5
We evaluated the effects of Silybum marianum, a herbal remedy, on menopausal symptoms, particularly hot flashes. In a well-structured study with eighty women, half were given S. marianum extract while the other half received a placebo over 12 weeks.
Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.
This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.
This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Read More
9.5
We investigated the effectiveness of the Phyto-Female Complex, a herbal blend, designed to alleviate menopausal symptoms in women aged 44-65. In a controlled trial involving 50 participants, those taking the herbal formula experienced a notable reduction in hot flushes and night sweats over three months.
By the end of the study, 47% of women in the treatment group reported no hot flushes, while only 19% in the placebo group saw similar relief. Participants also enjoyed better sleep quality, highlighting the Formula's potential as a safe option for managing menopausal discomfort.
By the end of the study, 47% of women in the treatment group reported no hot flushes, while only 19% in the placebo group saw similar relief. Participants also enjoyed better sleep quality, highlighting the Formula's potential as a safe option for managing menopausal discomfort.
Read More
8
Silymarin shows promise for osteoporosis
We delved into the potential effects of silymarin, derived from milk thistle, on osteoporosis, which is particularly concerning for postmenopausal women. The study highlighted how silymarin could promote bone formation and aid in fracture healing by demonstrating antioxidant properties.
In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
Read More
4
We investigated the effects of naturopathic botanical supplements, including silybum marianum, and dietary changes on hormone levels in premenopausal women over five menstrual cycles.
The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.
While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.
Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.
While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.
Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Post-menopause refreshment
2 people found this helpful
Excellent! During menopause, I noticed my liver function declined. Drinking this before bed has me feeling refreshed in the mornings. I would like to continue using it for a while longer.
Read More
7.5
Symptoms improvement
1 people found this helpful
My liver function worsened during menopause, with elevated values. After six months on this product, I’ve noticed slight improvement. I’ll continue using it to see further effects.
Read More
7.5
Improved energy
52 people found this helpful
Effective ants for dullness! I realised that my liver was burdened while approaching menopause. I used to rely on energy drinks but now I can move when I find it hard! I’ve been drinking a combination of products, but this one is more reasonable and effective. If you are a middle-aged person feeling tired and dull, you should definitely try this. I’m grateful to have discovered it.
Read More
7.5
Better mornings
28 people found this helpful
I’ve been using this for liver care alongside my chronic illness medications. I take one tablet in the morning, and since I started, I wake up feeling better and move quickly. Menopause had made my days heavy, but I feel my liver has improved thanks to silymarin. I will continue taking these supplements for my health.
Read More
7.5
Detox benefits
I started taking milk thistle during a detox protocol and continued for overall body maintenance. Since then, my skin has cleared up, digestion has improved, and my critical days have become more manageable. It's advisable to take it as a preventive measure before menopause, as my nutritionist suggested.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Saberi Z, Gorji N, Memariani Z, Moeini R, Shirafkan H, et al. Evaluation of the effect of Silybum marianum extract on menopausal symptoms: A randomized, double-blind placebo-controlled trial. Phytother Res. 2020;34:3359. 10.1002/ptr.6789
- Mohd Fozi NF, Mazlan M, Shuid AN, Isa Naina M. Milk thistle: a future potential anti-osteoporotic and fracture healing agent. Curr Drug Targets. 2013;14:1659. PubMed
- Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW. A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev. 2007;16:1601. PubMed
- Rotem C, Kaplan B. Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study. Gynecol Endocrinol. 2007;23:117. PubMed
Data last updated:
