Last update
3/16/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
Top Medical Research Studies
8
We explored how silymarin helps with obesity and muscle atrophy in mice. In our study, we divided the mice into three groups: a control group on a normal diet, another group on a high-fat diet, and a third group receiving silymarin alongside the high-fat diet.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
Read More
8
Our investigation focused on how dietary milk thistle seeds and seed oil impact obesity-related intestinal, liver, and lipid issues, specifically in genetically obese rats. After five weeks, we found that rats supplemented with milk thistle seeds showed more significant improvements in liver fat and cholesterol levels compared to those receiving seed oil.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Read More
8
Milk thistle extract may aid obesity
We explored the potential of a silymarin-enriched extract from milk thistle to aid in managing obesity and related inflammation. This study tested the extract's effect on activating thermogenesis in a model of obesity induced by a high-fat diet.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Read More
Most Useful Reviews
9
Enhanced energy levels
6 people found this helpful
Initially sceptical, I found Silymarin effective for my fatty liver caused by obesity. Within two weeks, my GGT levels decreased by 20, and I feel significantly better—more energetic and free from heartburn. I’m pleased with the results from taking two capsules daily.
Read More
7.5
Significant improvement
38 people found this helpful
Although I rarely drink alcohol, I have obesity-related fatty liver. I resumed taking milk thistle after a long break, and my blood tests markedly improved after one bottle. I had been sceptical due to my previous lack of results, but I am now continuing with it as it seems to help.
Read More
9
Weight reduction success
3 people found this helpful
Two and a half years ago, my doctor warned me to change my diet to avoid cirrhosis. Since then, I’ve embraced a healthier lifestyle, lost 25 kg, and used milk thistle to support my liver recovery through my obesity journey. I can attest that this approach works.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
- All Researches
9
Silybum marianum shows potential benefits
We examined a new oral supplement that combines prebiotics, yeast β-glucans, minerals, and Silybum marianum to see how it impacts obesity. Using a controlled study with mice, we found that this combination significantly improved energy balance and reduced inflammation.
After 28 days of treatment, mice on a high-fat diet showed lower blood sugar and fat levels, along with reduced liver damage indicators. While these findings are promising, it's essential to continue research to confirm these effects in humans.
After 28 days of treatment, mice on a high-fat diet showed lower blood sugar and fat levels, along with reduced liver damage indicators. While these findings are promising, it's essential to continue research to confirm these effects in humans.
Read More
8
Milk thistle extract may aid obesity
We explored the potential of a silymarin-enriched extract from milk thistle to aid in managing obesity and related inflammation. This study tested the extract's effect on activating thermogenesis in a model of obesity induced by a high-fat diet.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Read More
8
We explored how silymarin helps with obesity and muscle atrophy in mice. In our study, we divided the mice into three groups: a control group on a normal diet, another group on a high-fat diet, and a third group receiving silymarin alongside the high-fat diet.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
Read More
8
Our investigation focused on how dietary milk thistle seeds and seed oil impact obesity-related intestinal, liver, and lipid issues, specifically in genetically obese rats. After five weeks, we found that rats supplemented with milk thistle seeds showed more significant improvements in liver fat and cholesterol levels compared to those receiving seed oil.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Read More
8
We investigated how milk thistle cold press oil (MTO) influences obesity and related health problems. In a study with mice on a high-fat diet, MTO was given for the last eight weeks. We found that MTO effectively reduced obesity, high blood sugar, and hypertension, while promoting healthier fat cell functions.
Additionally, MTO helped lower inflammation in both fat and liver tissues, and improved liver health as well. These positive outcomes suggest that MTO may be a valuable addition to the diets of those dealing with obesity and its complications.
Additionally, MTO helped lower inflammation in both fat and liver tissues, and improved liver health as well. These positive outcomes suggest that MTO may be a valuable addition to the diets of those dealing with obesity and its complications.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Enhanced energy levels
6 people found this helpful
Initially sceptical, I found Silymarin effective for my fatty liver caused by obesity. Within two weeks, my GGT levels decreased by 20, and I feel significantly better—more energetic and free from heartburn. I’m pleased with the results from taking two capsules daily.
Read More
7.5
Significant improvement
38 people found this helpful
Although I rarely drink alcohol, I have obesity-related fatty liver. I resumed taking milk thistle after a long break, and my blood tests markedly improved after one bottle. I had been sceptical due to my previous lack of results, but I am now continuing with it as it seems to help.
Read More
9
Weight reduction success
3 people found this helpful
Two and a half years ago, my doctor warned me to change my diet to avoid cirrhosis. Since then, I’ve embraced a healthier lifestyle, lost 25 kg, and used milk thistle to support my liver recovery through my obesity journey. I can attest that this approach works.
Read More
8
Bile flow improvement
2 people found this helpful
I've found that Silymarin improves bile flow, which is essential for preventing stone formation. It’s especially beneficial for individuals with hepatitis or obesity. I experienced relief from spasms within 20 minutes of taking it, and its anti-inflammatory effects were quite noticeable.
Read More
6
Quality product
I purchased this supplement due to poor liver values linked to my obesity and multiple supplements I've been taking. Despite my Asteraceae allergy, I've had no adverse effects. The large capsules seem effective.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Reguero M, Reglero G, Quintela JC, Ramos-Ruiz R, Ramírez de Molina A, et al. Silymarin-Enriched Extract from Milk Thistle Activates Thermogenesis in a Preclinical Model of High-Fat-Diet-Induced Obesity to Relieve Systemic Meta-Inflammation. Nutrients. 2024;16. 10.3390/nu16234166
- Santamarina AB, de Freitas JA, Franco LAM, Nehmi-Filho V, Fonseca JV, et al. Nutraceutical blends predict enhanced health via microbiota reshaping improving cytokines and life quality: a Brazilian double-blind randomized trial. Sci Rep. 2024;14:11127. 10.1038/s41598-024-61909-3
- Nehmi-Filho V, Santamarina AB, de Freitas JA, Trarbach EB, de Oliveira DR, et al. Novel nutraceutical supplements with yeast β-glucan, prebiotics, minerals, and (silymarin) ameliorate obesity-related metabolic and clinical parameters: A double-blind randomized trial. Front Endocrinol (Lausanne). 2022;13:1089938. 10.3389/fendo.2022.1089938
- Kim S, You Y, Kim OK, Lee J, Chung JW, et al. Silymarin Prevents High-Fat Diet-Induced Muscle Atrophy by Regulating Protein Degradation and Synthesis in Mice. J Med Food. 2022;25:793. 10.1089/jmf.2021.K.0175
- Opyd PM, Jurgoński A. Intestinal, liver and lipid disorders in genetically obese rats are more efficiently reduced by dietary milk thistle seeds than their oil. Sci Rep. 2021;11:20895. 10.1038/s41598-021-00397-1
- Nehmi VA, Murata GM, Moraes RCM, Lima GCA, De Miranda DA, et al. A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice. J Integr Med. 2021;19:439. 10.1016/j.joim.2021.05.002
- Shen HH, Alex R, Bellner L, Raffaele M, Licari M, et al. Milk thistle seed cold press oil attenuates markers of the metabolic syndrome in a mouse model of dietary-induced obesity. J Food Biochem. 2020;44:e13522. 10.1111/jfbc.13522
- Guarino G, Strollo F, Carbone L, Della Corte T, Letizia M, et al. Bioimpedance analysis, metabolic effects and safety of the association Berberis aristata/Bilybum marianum: a 52-week double-blind, placebo-controlled study in obese patients with type 2 diabetes. J Biol Regul Homeost Agents. 2017;31:495.
Data last updated:
