In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
Most Useful Reviews
9
Effective flu prevention
5 people found this helpful
This zinc product has greatly improved my immune system. At the onset of flu season, I hardly get sick. It’s a great product from a reputable company and very affordable. I highly recommend this supplement!
Read More
9
No flu since use
1 people found this helpful
Remarkably, I haven’t had the flu or bronchitis since using this supplement. I even travelled to New Zealand and Australia without falling ill!
Read More
10
No flu episodes
Big dose Since I began taking zinc, my frequent flu episodes throughout the year have ceased. A splendid product.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
User Reviews
USERS' SCORE
Good
Based on 24 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Effective flu prevention
5 people found this helpful
This zinc product has greatly improved my immune system. At the onset of flu season, I hardly get sick. It’s a great product from a reputable company and very affordable. I highly recommend this supplement!
Read More
9
No flu since use
1 people found this helpful
Remarkably, I haven’t had the flu or bronchitis since using this supplement. I even travelled to New Zealand and Australia without falling ill!
Read More
10
No flu episodes
Big dose Since I began taking zinc, my frequent flu episodes throughout the year have ceased. A splendid product.
Read More
9
Improves flu resistance
This strong zinc supplement has been a fantastic addition to my health regimen. I've noticed improvements in my skin and overall resistance. I've remained healthy during the seasonal flu, which is very gratifying. The capsules are easy to swallow, and I highly recommend this effective product for immune support!
Read More
9
Boosts immunity, flu
This product is a great help for flu processes and enhances immunity. I recommend it as the doses are suitable.
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential benefits in managing cold and flu symptoms, and there is some evidence to suggest that it may help reduce the severity and duration of these illnesses. Several clinical studies have indicated that zinc supplements can shorten the duration of cold symptoms if taken within the first 24 hours of their onset. While zinc may not necessarily prevent you from getting the flu, it could aid in alleviating symptoms and supporting your immune system during illness.
It's important to consider the appropriate dosage and consult with a healthcare provider before starting any supplementation, as excessive zinc intake can lead to adverse effects. Zinc lozenges and supplements can be helpful, but they should be part of a broader approach to flu prevention that includes vaccinations, maintaining a healthy lifestyle, and good hygiene practices. If you experience flu symptoms, it's always a good idea to consult a healthcare professional for tailored advice and treatment options.
Based on user reviews, many individuals report seeing improvements in their immune system and a reduction in flu symptoms after a relatively short period of use. For instance, one user noted observable benefits just after one week of taking zinc supplements, stating, “I noticed an improvement in my immune system after about a week” Read Review. Another user echoed similar sentiments, emphasizing that after starting the supplement, they hadn't caught a cold or flu for months, suggesting a significant change in their health status over time Read Review.
Moreover, users have indicated that taking zinc promptly at the first signs of flu symptoms can also lead to quick relief, with some mentioning that it effectively manages their symptoms during flu season Read Review. While individual responses can vary, it seems that regular supplement intake may lead to noticeable results within a week, with continued benefits over a longer period of consistent use.
Based on recent research, zinc has demonstrated promising potential in the fight against influenza. Studies indicate that zinc plays a key role in modulating immune responses and may aid in reducing the severity and duration of flu symptoms. For instance, one study found that gargling with a mouthwash containing zinc significantly reduced both the frequency and severity of upper respiratory symptoms, although the exact contribution of zinc specifically remains unclear [1]. Another study highlighted zinc's indirect role in preventing the flu by lowering the expression levels of a molecule critical for influenza virus entry into cells, suggesting that it could be a part of preventive treatments [2].
Moreover, zinc's combination with natural compounds has been shown to reduce the viral loads of respiratory RNA viruses, including the flu, by significantly decreasing viral genome replication [3]. The extract of Euglena, which contains zinc, was observed to enhance the body's defense mechanisms against various strains of the influenza virus, showcasing its potential efficacy in flu treatment [4]. Overall, the collected evidence points towards zinc being a beneficial supplement for flu prevention and management, highlighting its importance in supporting immune health and reducing flu symptoms [5].
Based on user reviews, many individuals have reported significant improvements in their immune system and a notable decrease in flu-related symptoms since starting zinc supplementation. For instance, one user shared that they had not experienced any flu episodes throughout the year, crediting the zinc for their inner strength during flu season Read Review. Another reviewer noted the effectiveness of zinc in preventing illness, stating they traveled internationally without falling ill, which underscores the supplement's potential in maintaining health during flu outbreaks Read Review.
Moreover, several users have highlighted that taking zinc promptly at the onset of flu symptoms can lead to quicker relief. One user reported that it significantly helped manage flu symptoms and even aided in skin health Read Review. Many have praised the product's effectiveness to improve overall well-being and decrease the frequency of flu-like illnesses, with some stating they have experienced fewer colds or shorter durations of cold and flu episodes while consistently taking zinc Read Review. While results can vary from person to person, the collective feedback indicates that regular zinc supplementation may offer significant health benefits, particularly during peak flu seasons.
Users have reported positive experiences when combining zinc supplements with other vitamins and minerals to enhance their immune response against flu symptoms. For instance, one reviewer highlighted that taking zinc along with Vitamin C significantly improves effectiveness during flu season Read Review. Another user mentioned a daily regimen that includes zinc, magnesium, and Vitamin D3, which they found helpful in addressing flu-like symptoms Read Review. This suggests that the synergistic effects of these supplements could potentially offer greater protection and symptom relief when combating flu viruses.
Moreover, some users have explicitly shared their success in managing flu symptoms when zinc is combined with other supplements. For example, one user stated that taking zinc with quercetin effectively helped them eliminate flu-like respiratory illnesses Read Review. Another emphasized that their flu symptoms became more manageable when zinc was taken alongside Vitamin C and D3 Read Review. Overall, user feedback indicates that combining zinc with additional supportive nutrients may enhance immune function and offer more comprehensive flu protection.
While specific optimal dosing for zinc in treating flu isn't definitively established in the research, studies underscore its potential benefits for immune support and symptom management. One research study highlights that regular gargling with a mouthwash containing 0.075% zinc led to a notable reduction in the frequency and severity of respiratory symptoms, suggesting that this concentration might be effective for managing mild flu symptoms [1]. Additionally, zinc's role in reducing viral load and aiding recovery is well documented, indicating that including zinc in various forms, such as zinc picolinate or through natural sources like Euglena extract, can enhance the body's ability to combat influenza [3].
In conclusion, while more research is needed to pinpoint an exact optimal dose for zinc specifically targeting flu, the existing studies indicate incorporating zinc at moderate levels may help lessen symptom severity and support recovery. Doses commonly suggested range between 10 to 25 mg daily, but it's essential to consult a healthcare provider for tailored guidance and to avoid excessive intake, which can lead to negative side effects. This holistic approach empowers your immune system to tackle the flu more effectively while integrating dietary and supplementation strategies [5].
9
No flu symptoms
Observable benefits after a week of use. In comparison to other zinc supplements, I found this one to be the most effective. I noticed an improvement in my immune system after about a week. I haven't experienced any flu symptoms throughout the winter, which is unusual for me. Highly recommended!
7.5
Avoided flu illness
I've been using NOW Foods L-OptiZinc for six months, and I haven't caught a cold or flu, a significant change for me. After missing a few orders, I caught a scratchy throat a day after a traveller visited. I'm ordering again!
9
Effective for symptoms
1 people found this helpful
This product really helps if taken promptly at the first signs of flu symptoms.
10
No flu episodes
Big dose Since I began taking zinc, my frequent flu episodes throughout the year have ceased. A splendid product.
9
No flu since use
1 people found this helpful
Remarkably, I haven’t had the flu or bronchitis since using this supplement. I even travelled to New Zealand and Australia without falling ill!
7.5
Reduces flu symptoms
Whenever I feel flu approaching, I take this supplement, which helps to lessen flu symptoms. It also helps manage my acne.
7.5
Less flu duration
I love Now Opti-Zinc. It's easy to take and includes copper too. I experience fewer colds and shorter coughing spells during winter since using it, making it a valuable addition to my routine.
9
Improves immunity
5 people found this helpful
L-OptiZinc, a zinc complexed with amino acids, is better absorbed and has significantly improved my immune system. It's effective when taken with Vitamin C during flu season. The veggie capsules are an added bonus.
7.5
Effective for flu
I take one at bedtime with magnesium for sleep and alongside D3, K2, selenium, magnesium, and vitamin C to combat any flu-like symptoms that may arise.
9
Wipes flu-like illnesses
I take zinc daily along with quercetin, and it effectively wipes away flu-like respiratory illnesses.
7.5
Supports flu recovery
Excellent quality! It's helping me manage my flu symptoms with Vitamin C and Vitamin D3.
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9
Zinc and flavonoids combat flu
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
References
Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. doi:10.1371/journal.pone.0316807
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. doi:10.3390/nu13113911
Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. doi:10.1007/s12011-021-02859-z