Last update
5/23/2026
Research Authors

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size:  1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 170 mg L-OptiZinc® Monomethionine)
30 mg
273%
Copper(from 3 mg Copper Amino Acid Chelate)
0.3 mg
33%
📅 Last updated:

Top Medical Research Studies

We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More

Most Useful Reviews

9
No heartburn noted
Despite having a slight smell, I found the size small and easy to drink. It does not cause heartburn, allowing me to continue taking it without issue.
Read More
7.5
Effective but queasy
I am currently practising the Fujikawa theory. It has a slight smell, but it is an easy-to-take size. I had heard it occasionally causes symptoms like heartburn. When I took several tablets at once, I felt queasy and experienced loose stools, so I only took one tablet. Overall, I found it effective and believe it is of high quality.
Read More

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Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No heartburn noted
Despite having a slight smell, I found the size small and easy to drink. It does not cause heartburn, allowing me to continue taking it without issue.
Read More
7.5
Effective but queasy
I am currently practising the Fujikawa theory. It has a slight smell, but it is an easy-to-take size. I had heard it occasionally causes symptoms like heartburn. When I took several tablets at once, I felt queasy and experienced loose stools, so I only took one tablet. Overall, I found it effective and believe it is of high quality.
Read More

Frequently Asked Questions

9
No heartburn noted
Despite having a slight smell, I found the size small and easy to drink. It does not cause heartburn, allowing me to continue taking it without issue.
7.5
Effective but queasy
I am currently practising the Fujikawa theory. It has a slight smell, but it is an easy-to-take size. I had heard it occasionally causes symptoms like heartburn. When I took several tablets at once, I felt queasy and experienced loose stools, so I only took one tablet. Overall, I found it effective and believe it is of high quality.
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.

References

  1. Hayashi A, Taki Y, Arai K, Sato S, Higashizono K, et al. Esophageal ulcer related to zinc deficiency following a total gastrectomy. Nutrition. 2023;110:111999. 10.1016/j.nut.2023.111999
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