Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 4 Researches
9
USERS' SCORE
Good
Based on 16 Reviews
8.5
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Total Sugars
1 g
***
Includes 1 g Added Sugars
2%**
Calcium
157 mg
12%
Papain (from Papaya) (90,000 USP)
45 mg
***
Amylase (240 DU)
6 mg
***
Protease (from Papaya) (9,600 USP)
6 mg
***
Papaya Fruit (Carica papaya)
3 mg
***

Top Medical Research Studies

9
Promising vaccine approach for influenza
We explored a new vaccine approach using papaya mosaic virus particles fused with a short influenza peptide. This innovative structure showed promise in generating strong immune responses after just one dose in mice. The results indicated that vaccinated mice were significantly protected from the flu, suggesting that this could pave the way for an effective, broadly protective vaccine. While the study used mouse models, the findings could provide insights into future influenza vaccine development.
Read More
We explored how papaya mosaic virus (PapMV) nanoparticles can enhance the immune response to the flu vaccine in a study involving mice and ferrets. Adding PapMV nanoparticles as an adjuvant led to a quicker and stronger antibody response, measurable just five days post-vaccination.

Importantly, these nanoparticles helped protect against lethal flu infections within just ten days of vaccination. This rapid response is particularly critical during pandemics when swift immunity is vital.
Read More
We investigated the possibility of using papaya mosaic virus (PapMV) as a platform for a universal influenza vaccine. Our research demonstrated that the PapMV-CP-M2e vaccine can effectively trigger mice's immune response, producing antibodies that target influenza-infected cells.

While the vaccine showed great promise, particularly when combined with adjuvants like alum, our focus emphasized the enhanced immunogenicity of the virus-like particles (VLPs). This study marks a significant advancement in vaccine development, showcasing the potential of plant virus proteins in combating influenza.
Read More

Most Useful Reviews

9
Effective control
15 people found this helpful
I have suffered from severe acid reflux for over 11 years. I tried many times to come off medications like Omerazole only to return quickly. After a recommendation, I am so pleased with the results. I have finally managed to stop taking my standard medication and my symptoms are now completely under control thanks to this supplement. I'm a huge fan!
Read More
9
Phenomenal results
6 people found this helpful
My acid reflux can be troublesome and standard antacids don't suffice. This product, however, works phenomenally well. I was amazed by its effectiveness and highly recommend it!
Read More
9
Effective relief
Great for acid reflux. I take 2-3 after a meal and feel fine.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 4 Researches
9
  • All Researches
We explored the potential of using papaya mosaic virus nanoparticles as an adjuvant to boost seasonal flu vaccines. The study involved immunizing mice and ferrets, which showed a stronger immune response to the flu virus, particularly in terms of recognized viral proteins. This method not only improved antibody production but also initiated robust cellular immunity. Overall, the findings suggest that papaya nanoparticles could significantly enhance flu vaccine effectiveness, potentially offering broader protection during outbreaks.
Read More
We investigated the possibility of using papaya mosaic virus (PapMV) as a platform for a universal influenza vaccine. Our research demonstrated that the PapMV-CP-M2e vaccine can effectively trigger mice's immune response, producing antibodies that target influenza-infected cells.

While the vaccine showed great promise, particularly when combined with adjuvants like alum, our focus emphasized the enhanced immunogenicity of the virus-like particles (VLPs). This study marks a significant advancement in vaccine development, showcasing the potential of plant virus proteins in combating influenza.
Read More
9
Promising vaccine approach for influenza
We explored a new vaccine approach using papaya mosaic virus particles fused with a short influenza peptide. This innovative structure showed promise in generating strong immune responses after just one dose in mice. The results indicated that vaccinated mice were significantly protected from the flu, suggesting that this could pave the way for an effective, broadly protective vaccine. While the study used mouse models, the findings could provide insights into future influenza vaccine development.
Read More
We explored how papaya mosaic virus (PapMV) nanoparticles can enhance the immune response to the flu vaccine in a study involving mice and ferrets. Adding PapMV nanoparticles as an adjuvant led to a quicker and stronger antibody response, measurable just five days post-vaccination.

Importantly, these nanoparticles helped protect against lethal flu infections within just ten days of vaccination. This rapid response is particularly critical during pandemics when swift immunity is vital.
Read More

User Reviews

USERS' SCORE
Good
Based on 16 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective control
15 people found this helpful
I have suffered from severe acid reflux for over 11 years. I tried many times to come off medications like Omerazole only to return quickly. After a recommendation, I am so pleased with the results. I have finally managed to stop taking my standard medication and my symptoms are now completely under control thanks to this supplement. I'm a huge fan!
Read More
9
Phenomenal results
6 people found this helpful
My acid reflux can be troublesome and standard antacids don't suffice. This product, however, works phenomenally well. I was amazed by its effectiveness and highly recommend it!
Read More
9
Effective relief
Great for acid reflux. I take 2-3 after a meal and feel fine.
Read More
9
GERD control
Beyond excellent! This enzyme helps us control GERD and acid reflux. We felt relief immediately. Thanks, American Health and iHerb.
Read More
7.5
Excellent relief
This product is very nice for acid reflux and provides very good relief.
Read More

Frequently Asked Questions

9
GERD control
Beyond excellent! This enzyme helps us control GERD and acid reflux. We felt relief immediately. Thanks, American Health and iHerb.
9
Pain reduction
I am very satisfied! This really helps with acid reflux and stomach pain.
9
Surprising results
1 people found this helpful
I had little hope for papaya enzymes aiding my acid reflux but was pleasantly surprised by their effectiveness. Instead of relying on OTC medications, I chew two tablets, which have significantly helped. I highly recommend them.
7.5
Symptom reduction
4 people found this helpful
We bought this for relief from reflux esophagitis symptoms. After dinner, I noticed a reduction in stomach discomfort and waking at night after taking three tablets. This delightful result, especially for the price, encourages me to continue using it.
We explored how papaya mosaic virus (PapMV) nanoparticles can enhance the immune response to the flu vaccine in a study involving mice and ferrets. Adding PapMV nanoparticles as an adjuvant led to a quicker and stronger antibody response, measurable just five days post-vaccination.

Importantly, these nanoparticles helped protect against lethal flu infections within just ten days of vaccination. This rapid response is particularly critical during pandemics when swift immunity is vital.
9
Promising vaccine approach for influenza
We explored a new vaccine approach using papaya mosaic virus particles fused with a short influenza peptide. This innovative structure showed promise in generating strong immune responses after just one dose in mice. The results indicated that vaccinated mice were significantly protected from the flu, suggesting that this could pave the way for an effective, broadly protective vaccine. While the study used mouse models, the findings could provide insights into future influenza vaccine development.
We explored the potential of using papaya mosaic virus nanoparticles as an adjuvant to boost seasonal flu vaccines. The study involved immunizing mice and ferrets, which showed a stronger immune response to the flu virus, particularly in terms of recognized viral proteins. This method not only improved antibody production but also initiated robust cellular immunity. Overall, the findings suggest that papaya nanoparticles could significantly enhance flu vaccine effectiveness, potentially offering broader protection during outbreaks.

References

  1. Rioux G, Carignan D, Russell A, Bolduc M, Gagné MÈ, et al. Influence of PapMV nanoparticles on the kinetics of the antibody response to flu vaccine. J Nanobiotechnology. 2016;14:43. 10.1186/s12951-016-0200-2
  2. Carignan D, Thérien A, Rioux G, Paquet G, Gagné ML, et al. Engineering of the PapMV vaccine platform with a shortened M2e peptide leads to an effective one dose influenza vaccine. Vaccine. 2015;33:7245. 10.1016/j.vaccine.2015.10.123
  3. Savard C, Guérin A, Drouin K, Bolduc M, Laliberté-Gagné ME, et al. Improvement of the trivalent inactivated flu vaccine using PapMV nanoparticles. PLoS One. 2011;6:e21522. 10.1371/journal.pone.0021522
  4. Denis J, Acosta-Ramirez E, Zhao Y, Hamelin ME, Koukavica I, et al. Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform. Vaccine. 2008;26:3395. 10.1016/j.vaccine.2008.04.052
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