Last update
5/3/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 26 Reviews
7.8
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Total Sugars
1 g
***
Includes 1 g Added Sugars
2%**
Calcium
157 mg
12%
Papain (from Papaya) (90,000 USP)
45 mg
***
Amylase (240 DU)
6 mg
***
Protease (from Papaya) (9,600 USP)
6 mg
***
Papaya Fruit (Carica papaya)
3 mg
***
Top Medical Research Studies
9
We investigated how a crude alkaloid extract from papaya leaves impacts Staphylococcus aureus, the bacteria responsible for food poisoning through its harmful enterotoxin A.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
Read More
Most Useful Reviews
9
Daily digestive maintenance
11 people found this helpful
This enzyme has become essential for my gastrointestinal health. One tablet post-meal prevents any bloating or heaviness. I'm now able to enjoy any food without concern, and I hardly recall needing other digestive aids. The tablets are sweet and tasty.
Read More
9
Digestive comfort
5 people found this helpful
These enzymes work wonders for bloating! They're affordably priced, especially in bulk, and help digest less healthy foods efficiently. They eliminate heaviness in my stomach and can even relieve mild heartburn with just one tablet. While they don't contain lipase for fat breakdown, at this price, it's hard to complain! Just a note for diabetics regarding sugar content.
Read More
9
Year-long use
2 people found this helpful
I’ve been using Papaya Enzyme for about a year. If I eat something that disrupts my stomach or overindulge, I chew three tablets, and I feel well again!
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We investigated how a crude alkaloid extract from papaya leaves impacts Staphylococcus aureus, the bacteria responsible for food poisoning through its harmful enterotoxin A.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 26 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Daily digestive maintenance
11 people found this helpful
This enzyme has become essential for my gastrointestinal health. One tablet post-meal prevents any bloating or heaviness. I'm now able to enjoy any food without concern, and I hardly recall needing other digestive aids. The tablets are sweet and tasty.
Read More
9
Digestive comfort
5 people found this helpful
These enzymes work wonders for bloating! They're affordably priced, especially in bulk, and help digest less healthy foods efficiently. They eliminate heaviness in my stomach and can even relieve mild heartburn with just one tablet. While they don't contain lipase for fat breakdown, at this price, it's hard to complain! Just a note for diabetics regarding sugar content.
Read More
9
Year-long use
2 people found this helpful
I’ve been using Papaya Enzyme for about a year. If I eat something that disrupts my stomach or overindulge, I chew three tablets, and I feel well again!
Read More
9
Comfort after feasts
1 people found this helpful
These enzymes have become my favourite! The large bottle is more economical than smaller packs, and they combine papain, amylase, and protease to support digestion. After over a year’s use, I can affirm they alleviate discomfort after feasting, significantly aiding in digesting heavy meals without any side effects.
Read More
9
Must-have for feasts
1 people found this helpful
These act like Mesima or Creon. After indulging in fatty or heavy foods during parties, I take 3 papaya tablets, and within half an hour, I feel light as if I haven't eaten at all. They are essential for birthdays and holidays!
Read More
Frequently Asked Questions
9
Must-have for feasts
1 people found this helpful
These act like Mesima or Creon. After indulging in fatty or heavy foods during parties, I take 3 papaya tablets, and within half an hour, I feel light as if I haven't eaten at all. They are essential for birthdays and holidays!
6
Eases overeating discomfort
19 people found this helpful
When I overindulge or eat rich foods, I take two or three tablets, which relieve discomfort within 10-15 minutes. The severity fades away thanks to papain. We always keep a jar of American Health papain at home for emergencies. The tablets are hard yet taste pleasant, making them easy to consume.
7.5
Positive support for digestion
3 people found this helpful
I gave this enzyme to my daughter experiencing digestive issues. The chewable tablets were easy for her to take without adverse reactions. After taking them three times a day, we saw positive results, and she now manages without them.
9
Comfort after feasts
1 people found this helpful
These enzymes have become my favourite! The large bottle is more economical than smaller packs, and they combine papain, amylase, and protease to support digestion. After over a year’s use, I can affirm they alleviate discomfort after feasting, significantly aiding in digesting heavy meals without any side effects.
7.5
Convenient option
3 people found this helpful
These natural papaya pills serve as a brilliant alternative to stronger medications like festal or mezim. They provide immediate relief from heaviness when food isn't well digested or after overeating. The convenience of chewing without water makes them an excellent addition to my wellbeing routine.
7.5
Prevents heaviness
4 people found this helpful
I use these enzymes around holiday celebrations, as my family indulges in large meals. They help prevent heaviness in my stomach by allowing the food to digest more efficiently, and I take them a few days before and after our feasting.
7.5
Improved nutrient absorption
235 people found this helpful
This is a wonderful supplement to take after meals. It greatly aids digestion, enabling better absorption of necessary nutrients and removal of toxins.
9
Year-long use
2 people found this helpful
I’ve been using Papaya Enzyme for about a year. If I eat something that disrupts my stomach or overindulge, I chew three tablets, and I feel well again!
7.5
Relief from heaviness
1 people found this helpful
Excellent! I bought these chewable enzymes for my child, who sometimes feels heaviness after food. I previously used probiotics from Animal Parade, but they were out of stock. These small, oval tablets dissolve easily and aid digestion. They quickly alleviate feelings of heaviness and bloating. I usually give 2 to my 6-year-old, and I occasionally take 3 myself. The effects are gentle but effective, promoting quicker digestive processes.
9
We investigated how a crude alkaloid extract from papaya leaves impacts Staphylococcus aureus, the bacteria responsible for food poisoning through its harmful enterotoxin A.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
We discovered that this extract significantly inhibits the growth of the bacteria and reduces the production of enterotoxin A. When tested, the extract led to a notable decrease in enterotoxin expression.
Although the papaya extract showed promise, it's essential to conduct further research to better understand its practical applications in food safety settings.
References
- Handayani L, Faridah DN, Kusumaningrum HD. Staphylococcal enterotoxin A gene-carrying Staphylococcus aureus isolated from foods and its control by crude alkaloid from papaya leaves. J Food Prot. 2014;77:1992. 10.4315/0362-028X.JFP-13-483
