Last update
3/24/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
110 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus sinensis) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**
Top Medical Research Studies
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
Read More
Most Useful Reviews
7.5
Child's nasal relief
1 people found this helpful
Helps improve nasal allergies. The child suffers from long-term nasal allergies, and though quercetin was ineffective, I give him two pills during inflammation. Otherwise, he often experiences a stuffy nose, which is very uncomfortable for him. However, the tablet is rather large, and he struggles to swallow it. I wouldn't recommend this for children.
Read More
9
Immune support
This high-quality product with natural ingredients helps well and does not cause allergies. There are no revealed side effects, and it comes in convenient packaging. It is suitable for all ages, supports health, and strengthens the immune system.
Read More
7.5
Positive change
1 people found this helpful
The pills are quite large, but they don't upset my stomach and provide a solid 1000mg of Vitamin C. They help with my allergies, although I still need to take Claritin daily. I've also started taking organic hemp extract to improve my immune system, but it may take time.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Child's nasal relief
1 people found this helpful
Helps improve nasal allergies. The child suffers from long-term nasal allergies, and though quercetin was ineffective, I give him two pills during inflammation. Otherwise, he often experiences a stuffy nose, which is very uncomfortable for him. However, the tablet is rather large, and he struggles to swallow it. I wouldn't recommend this for children.
Read More
9
Immune support
This high-quality product with natural ingredients helps well and does not cause allergies. There are no revealed side effects, and it comes in convenient packaging. It is suitable for all ages, supports health, and strengthens the immune system.
Read More
7.5
Positive change
1 people found this helpful
The pills are quite large, but they don't upset my stomach and provide a solid 1000mg of Vitamin C. They help with my allergies, although I still need to take Claritin daily. I've also started taking organic hemp extract to improve my immune system, but it may take time.
Read More
7.5
Digestible solution
Helpful for allergies and very easy to digest.
Read More
Frequently Asked Questions
7.5
Child's nasal relief
1 people found this helpful
Helps improve nasal allergies. The child suffers from long-term nasal allergies, and though quercetin was ineffective, I give him two pills during inflammation. Otherwise, he often experiences a stuffy nose, which is very uncomfortable for him. However, the tablet is rather large, and he struggles to swallow it. I wouldn't recommend this for children.
9
Immune support
This high-quality product with natural ingredients helps well and does not cause allergies. There are no revealed side effects, and it comes in convenient packaging. It is suitable for all ages, supports health, and strengthens the immune system.
7.5
Digestible solution
Helpful for allergies and very easy to digest.
References
- Jesenak M, Hrubisko M, Chudek J, Bystron J, Rennerova Z, et al. Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma. Sci Rep. 2025;15:7146. 10.1038/s41598-025-91830-2
