Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
110 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus sinensis) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**

Top Medical Research Studies

7
Vitamin C's unclear influenza impact
We explored the relationship between vitamin C and influenza, delving into various studies conducted from 2000 to June 2021. In our analysis of the research, we found eleven studies that specifically examined the effects of vitamin C on influenza.

While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.

Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.

Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
Read More
7
Vitamin C impacts respiratory mortality
We examined how serum levels of vitamin C could influence mortality rates from influenza and pneumonia. The study analyzed data from 7,428 participants aged 45 and older, utilizing information from the National Health and Nutrition Examination Survey (NHANES-III).

Through our research, we discovered that vitamin C, along with other antioxidants like carotenoids, showed a nonlinear relationship with mortality from these respiratory illnesses. Specifically, those in the third quartile of serum vitamin C displayed a lower risk of dying from influenza or pneumonia compared to those in the lowest quartile, with a hazard ratio of 0.38.

This implies that having a moderately high level of vitamin C may help reduce the risk of mortality from these diseases. However, the protective effect seemed to weaken for those in the highest quartile of vitamin C, suggesting a more complex relationship.

Overall, this study highlights the potential benefits of maintaining healthy levels of vitamin C in the blood, indicating that antioxidant intake may positively influence mortality risk among adults facing influenza or pneumonia. Nevertheless, more research is needed in diverse populations to confirm these findings and explore their implications further.
Read More
7
Vitamin C's impact on RTIs
We systematically reviewed how vitamin C affects respiratory tract infections (RTIs), including influenza. This involved analyzing results from numerous studies to understand how effective vitamin C is in either preventing these infections or alleviating their symptoms.

Our findings reveal that vitamin C supplementation can reduce the risk of RTIs, with a reported risk ratio of 0.96. This means that taking vitamin C may lower the chance of getting an RTI compared to not taking it at all.

Additionally, we observed that vitamin C can help shorten the duration of symptoms by approximately 9%, making recovery from a potential influenza infection a bit quicker. Interestingly, the benefits of vitamin C seemed to be more pronounced among men and in populations from middle-income countries, compared to women and those in higher-income areas.

While the results are promising, it’s essential to note that vitamin C alone might not be a complete solution for preventing influenza. More research is necessary to fully understand its effectiveness, particularly in light of other emerging viruses and health challenges.
Read More

Most Useful Reviews

9.5
Speeds recovery
This product is useful and helps combat influenza. It improves resistance to respiratory illnesses and alleviates sore throats, thereby speeding up recovery from influenza.
Read More
8
Minimises contamination
Ester-C protects against viruses. My wife and I take half tablets daily to guard ourselves, especially during influenza outbreaks. It effectively reduces the risk of contamination. I believe it’s better to take a small continuous dose than a larger one infrequently. It’s the best in terms of price and quality among its peers!
Read More
7.3
Excellent for immunity
I received a large package containing 180 capsules. It is excellent for boosting immunity, particularly when infected with influenza. The quantity provided is superb.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
  • All Researches
9
Vitamin C supports antiviral activity
We investigated the potential of a unique formulation combining vitamin C with a complex of alkaloids to combat the H1N1 influenza virus. Our approach involved creating nanoparticles that encapsulate both the alkaloid-rich fraction and ascorbic acid (vitamin C) to enhance the water solubility and bioavailability of these components.

The results were promising, showing that our formulated nanoparticles had a significant selective antiviral effect against the H1N1 virus, achieving an IC50 of 2.7 μg/mL. Notably, this effect was observed without harming the host cells, suggesting that the treatment could be both effective and safe.

However, it's important to note that while the presence of vitamin C in the formulation seems beneficial, we also included other active ingredients, making it difficult to assess the isolated impact of vitamin C alone. The combination of these elements appears to contribute to the overall effectiveness against influenza.

In summary, our findings indicate that this new delivery system might be a promising avenue for treating influenza viruses, with vitamin C playing a supportive role among other powerful components.
Read More
7
Vitamin C's unclear influenza impact
We explored the relationship between vitamin C and influenza, delving into various studies conducted from 2000 to June 2021. In our analysis of the research, we found eleven studies that specifically examined the effects of vitamin C on influenza.

While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.

Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.

Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
Read More
We investigated how an acupoint injection containing vitamin C and B complex affected pneumonia triggered by the influenza A virus in mice. In our study, we used 60 male mice that were divided into six groups to evaluate the effectiveness of the treatment. One group received the vitamin solution through acupoint injections, while others received it through different methods, including intraperitoneally and at non-target points.

Our findings indicated that the acupoint injections helped reduce inflammatory responses and oxidative stress in the lung tissue of the mice. We observed improvements in survival rates and longer survival times, despite no significant impact on the viral load in the lungs. This suggests that while vitamin injections can offer some protective benefits, they do not eliminate the virus itself.

Overall, while we found some positive effects of using the V+VCo solution, the results highlight the complexity of treating viral infections like influenza. It seems that vitamin C, combined with other vitamins, can be beneficial for managing symptoms, but it doesn't directly attack the virus.
Read More
7
Vitamin C impacts respiratory mortality
We examined how serum levels of vitamin C could influence mortality rates from influenza and pneumonia. The study analyzed data from 7,428 participants aged 45 and older, utilizing information from the National Health and Nutrition Examination Survey (NHANES-III).

Through our research, we discovered that vitamin C, along with other antioxidants like carotenoids, showed a nonlinear relationship with mortality from these respiratory illnesses. Specifically, those in the third quartile of serum vitamin C displayed a lower risk of dying from influenza or pneumonia compared to those in the lowest quartile, with a hazard ratio of 0.38.

This implies that having a moderately high level of vitamin C may help reduce the risk of mortality from these diseases. However, the protective effect seemed to weaken for those in the highest quartile of vitamin C, suggesting a more complex relationship.

Overall, this study highlights the potential benefits of maintaining healthy levels of vitamin C in the blood, indicating that antioxidant intake may positively influence mortality risk among adults facing influenza or pneumonia. Nevertheless, more research is needed in diverse populations to confirm these findings and explore their implications further.
Read More
7
Vitamin C's impact on RTIs
We systematically reviewed how vitamin C affects respiratory tract infections (RTIs), including influenza. This involved analyzing results from numerous studies to understand how effective vitamin C is in either preventing these infections or alleviating their symptoms.

Our findings reveal that vitamin C supplementation can reduce the risk of RTIs, with a reported risk ratio of 0.96. This means that taking vitamin C may lower the chance of getting an RTI compared to not taking it at all.

Additionally, we observed that vitamin C can help shorten the duration of symptoms by approximately 9%, making recovery from a potential influenza infection a bit quicker. Interestingly, the benefits of vitamin C seemed to be more pronounced among men and in populations from middle-income countries, compared to women and those in higher-income areas.

While the results are promising, it’s essential to note that vitamin C alone might not be a complete solution for preventing influenza. More research is necessary to fully understand its effectiveness, particularly in light of other emerging viruses and health challenges.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Speeds recovery
This product is useful and helps combat influenza. It improves resistance to respiratory illnesses and alleviates sore throats, thereby speeding up recovery from influenza.
Read More
8
Minimises contamination
Ester-C protects against viruses. My wife and I take half tablets daily to guard ourselves, especially during influenza outbreaks. It effectively reduces the risk of contamination. I believe it’s better to take a small continuous dose than a larger one infrequently. It’s the best in terms of price and quality among its peers!
Read More
7.3
Excellent for immunity
I received a large package containing 180 capsules. It is excellent for boosting immunity, particularly when infected with influenza. The quantity provided is superb.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Park JH, Lee Y, Choi M, Park E. The Role of Some Vitamins in Respiratory-related Viral Infections: A Narrative Review. Clin Nutr Res. 2023;12:77. doi:10.7762/cnr.2023.12.1.77
  2. Liu MJ, Han ZY, Wang HW, Yu CL, Xu XL, et al. [Effect and mechanism of acupoint injection on influenza A virus induced pneumonia in mice]. Zhongguo Zhen Jiu. 2022;42:1017. doi:10.13703/j.0255-2930.20210713-k0002
  3. Fahmy SA, Mahdy NK, Al Mulla H, ElMeshad AN, Issa MY, et al. PLGA/PEG Nanoparticles Loaded with Cyclodextrin- Alkaloid Complex and Ascorbic Acid with Promising Antimicrobial Activities. Pharmaceutics. 2022;14. doi:10.3390/pharmaceutics14010142
  4. Kang H, Hu H, Park SK. Serum antioxidant status and mortality from influenza and pneumonia in US adults. Public Health Nutr. 2022;25:1. doi:10.1017/S1368980022000027
  5. Abioye AI, Bromage S, Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob Health. 2021;6. doi:10.1136/bmjgh-2020-003176
  6. Márquez-Domínguez L, Reyes-Leyva J, Herrera-Camacho I, Santos-López G, Scior T. Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus. Molecules. 2020;25. doi:10.3390/molecules25184248
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