5/19/2025
Last update
5/19/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.4
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%**
Total Sugars
0 g
†
Incl. 0 g Added Sugars
0%**
Intelliflora™ Blend:
150 mg5 billion CFUs
Lactobacillus crispatus LBV 88
†
Lactobacillus rhamnosus LBV 96
†
Lactobacillus gasseri LBV 150N
†
Lactobacillus jensenii LBV 116
†
Top Medical Research Studies
9
Probiotic may stabilize estrogen levels
We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Read More
9
We investigated how orally administered probiotics, particularly Lactobacillus rhamnosus, can impact the vaginal flora of postmenopausal women. In a randomized, double-blind study, participants received either probiotic capsules or a placebo for 14 days.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Read More
8
We explored the role of Lactobacillus in postmenopausal women through a detailed analysis of vaginal microbiota and inflammation markers.
This study involved a subset of women from a larger trial, assessing various treatment options for vulvovaginal discomfort.
We found that even after menopause, Lactobacillus dominance correlates with reduced inflammatory markers in the vagina. This indicates that keeping a healthy balance of Lactobacillus can still positively influence vaginal health post-menopause.
This study involved a subset of women from a larger trial, assessing various treatment options for vulvovaginal discomfort.
We found that even after menopause, Lactobacillus dominance correlates with reduced inflammatory markers in the vagina. This indicates that keeping a healthy balance of Lactobacillus can still positively influence vaginal health post-menopause.
Read More
Most Useful Reviews
9
Yeast infections free
32 people found this helpful
Best to balance pH! If you suffer from recurring yeast infections during perimenopause, this is what you need! After having several infections, my doctor advised that my stress and perimenopause were to blame. I tried this product from my local grocery store and have been yeast infection free for six months. I’ve even subscribed to it as a prime member for regular delivery!
Read More
9
UTIs resolved
7 people found this helpful
Works great for recurring UTIs. After menopause, I experienced frequent UTIs. My doctor put me on progesterone, but the issues persisted. I tried Azo Probiotics and haven't had a UTI since. I highly recommend it!
Read More
7.5
Irritation relief
5 people found this helpful
The best, fast-acting daily capsule! If you're having minor irritations from perimenopause and hormonal changes, you must try this! After negative tests for BV and yeast, I was frustrated. My doctor suggested boric acid, which worked initially but the irritation returned. My cousin recommended this probiotic – I chose it because I trust the AZO brand, and it did not disappoint. It worked quickly, alleviating irritation and even assisting with slight dryness. Healthy Vijay! Yay!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.4
- All Researches
9
Probiotics improve post-menopausal vaginal health
We explored the potential of probiotics to enhance vaginal health in post-menopausal women. Through a clinical trial involving 50 participants aged 45 to 65, we administered a daily probiotic supplement for 28 days.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
Read More
9
Lactobacillus effective for vaginal health
We evaluated the effects of VagiBIOM, a Lactobacillus-based vaginal suppository, on vaginal health among peri- and premenopausal women facing bacterial vaginosis (BV). In a randomized, double-blind, placebo-controlled trial with 66 participants, we measured changes in vaginal pH and health after 4 weeks of treatment.
Results showed significant improvements in vaginal health index scores and reductions in vaginal pH and itching symptoms. Notably, two Lactobacillus species identified in the treatment group indicated enhanced vaginal microbiome diversity. VagiBIOM appears effective in relieving BV-related symptoms in women experiencing menopause.
Results showed significant improvements in vaginal health index scores and reductions in vaginal pH and itching symptoms. Notably, two Lactobacillus species identified in the treatment group indicated enhanced vaginal microbiome diversity. VagiBIOM appears effective in relieving BV-related symptoms in women experiencing menopause.
Read More
9
Probiotic may stabilize estrogen levels
We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Read More
9
We investigated how orally administered probiotics, particularly Lactobacillus rhamnosus, can impact the vaginal flora of postmenopausal women. In a randomized, double-blind study, participants received either probiotic capsules or a placebo for 14 days.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Read More
This study explored the effects of Pterocarpus mildbraedii water extract on vaginal dysbiosis and cardiovascular disease risks in a menopausal rat model. We found that the extract shows estrogen-like properties which can positively influence vaginal health and potentially reduce cardiovascular concerns.
Using several analysis methods, we noted that the extract helps maintain healthy Lactobacillus levels, vital for vaginal flora, and can combat oxidative stress. Overall, Pterocarpus mildbraedii emerges as a promising candidate for addressing menopause-related health issues.
Using several analysis methods, we noted that the extract helps maintain healthy Lactobacillus levels, vital for vaginal flora, and can combat oxidative stress. Overall, Pterocarpus mildbraedii emerges as a promising candidate for addressing menopause-related health issues.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Yeast infections free
32 people found this helpful
Best to balance pH! If you suffer from recurring yeast infections during perimenopause, this is what you need! After having several infections, my doctor advised that my stress and perimenopause were to blame. I tried this product from my local grocery store and have been yeast infection free for six months. I’ve even subscribed to it as a prime member for regular delivery!
Read More
9
UTIs resolved
7 people found this helpful
Works great for recurring UTIs. After menopause, I experienced frequent UTIs. My doctor put me on progesterone, but the issues persisted. I tried Azo Probiotics and haven't had a UTI since. I highly recommend it!
Read More
7.5
Irritation relief
5 people found this helpful
The best, fast-acting daily capsule! If you're having minor irritations from perimenopause and hormonal changes, you must try this! After negative tests for BV and yeast, I was frustrated. My doctor suggested boric acid, which worked initially but the irritation returned. My cousin recommended this probiotic – I chose it because I trust the AZO brand, and it did not disappoint. It worked quickly, alleviating irritation and even assisting with slight dryness. Healthy Vijay! Yay!
Read More
6
Natural balance restoration
1 people found this helpful
I chose probiotics for women's health for a long time and have read many positive reviews about this supplement. It has a good quality composition, poses no side effects, and is easy to use. I hope it will help restore the natural balance of good and bad bacteria during menopause. For optimal results, one should take it for at least six weeks.
Read More
7.5
Health improvement
This daily probiotic is safe for pregnant women. During menopause, it's common to experience ailments in sensitive areas, but by regularly taking probiotics, I can enhance my health.
Read More
Frequently Asked Questions
6
Natural balance restoration
1 people found this helpful
I chose probiotics for women's health for a long time and have read many positive reviews about this supplement. It has a good quality composition, poses no side effects, and is easy to use. I hope it will help restore the natural balance of good and bad bacteria during menopause. For optimal results, one should take it for at least six weeks.
7.5
Health improvement
This daily probiotic is safe for pregnant women. During menopause, it's common to experience ailments in sensitive areas, but by regularly taking probiotics, I can enhance my health.
9
Probiotics improve post-menopausal vaginal health
We explored the potential of probiotics to enhance vaginal health in post-menopausal women. Through a clinical trial involving 50 participants aged 45 to 65, we administered a daily probiotic supplement for 28 days.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
9
Probiotic may stabilize estrogen levels
We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
References
- Sandrine MNY, Michel BG, Bibi-Farouck AO, Ngo Bahebeck P, Emmanuel OP, et al. In silico molecular docking and predictive ADME properties, in vitro antioxidant scavenging capacities, and in vivo pharmacological activities to study the potential of Pterocarpus mildbraedii's Harms (Fabaceae) in preventing vaginal dysbiosis and risk factors for cardiovascular disease in an estropause rat model. Fitoterapia. 2025;183:106496. 10.1016/j.fitote.2025.106496
- Dabeer S, Tripathi AK, Weiss D, Vikulina T, Ofotokun I, et al. Combined Sequential Antiretroviral Therapy-Induced Immune Reconstitution Bone Loss and Estrogen Deficiency Bone Loss are Cumulative in Mice Models. J Infect Dis. 2024. 10.1093/infdis/jiae643
- Zeng Q, Shu H, Pan H, Zhang Y, Fan L, et al. Associations of vaginal microbiota with the onset, severity, and type of symptoms of genitourinary syndrome of menopause in women. Front Cell Infect Microbiol. 2024;14:1402389. 10.3389/fcimb.2024.1402389
- De Leo V, Governini L, Ponchia R, Recalcati D, Murina F. Effectiveness of Combination of Tibolone and Plus Lactoferrin in Postmenopausal Women with Vulvar Vestibular Pain: A Preliminary Report. Nutrients. 2024;16. 10.3390/nu16142378
- Harahap IA, Moszak M, Czlapka-Matyasik M, Skrypnik K, Bogdański P, et al. Effects of daily probiotic supplementation with on calcium status, bone metabolism biomarkers, and bone mineral density in postmenopausal women: a controlled and randomized clinical study. Front Nutr. 2024;11:1401920. 10.3389/fnut.2024.1401920
- Byrne EH, Song H, Srinivasan S, Fredricks DN, Reed SD, et al. Association between vaginal microbiota and vaginal inflammatory immune markers in postmenopausal women. Menopause. 2024;31:575. 10.1097/GME.0000000000002362
- Resciniti SM, Biesiekierski JR, Ghasem-Zadeh A, Moschonis G. The Effectiveness of a Lactobacilli-Based Probiotic Food Supplement on Bone Mineral Density and Bone Metabolism in Australian Early Postmenopausal Women: Protocol for a Double-Blind Randomized Placebo-Controlled Trial. Nutrients. 2024;16. 10.3390/nu16081150
- Vicariotto F, Malfa P, Viciani E, Dell'Atti F, Squarzanti DF, et al. Efficacy of PBS067, subsp. BL050, and LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial. Nutrients. 2024;16. 10.3390/nu16030402
- Vivekanandan V, Khan ZH, Venugopal G, Musunuru B, Mishra P, et al. VagiBIOM Lactobacillus suppository improves vaginal health index in perimenopausal women with bacterial vaginosis: a randomized control trial. Sci Rep. 2024;14:3317. 10.1038/s41598-024-53770-1
- Bayat Z, Damirchi A, Hasannejad-Bibalan M, Babaei P. Metabotropic Effect of Probiotic Supplementation and High-Intensity Interval Training in Menopause-Induced Metabolic Syndrome in Rats. J Menopausal Med. 2023;29:29. 10.6118/jmm.22037
- Sawada D, Sugawara T, Hirota T, Nakamura Y. Effects of CP2305 on Mild Menopausal Symptoms in Middle-Aged Women. Nutrients. 2022;14. 10.3390/nu14091695
- Bhardwaj A, Sapra L, Madan D, Ahuja V, Sharma HP, et al. Gut-resident Tregs (GTregs) play a pivotal role in maintaining bone health under post-menopausal osteoporotic conditions. J Leukoc Biol. 2025. 10.1093/jleuko/qiaf008
- Honda S, Tominaga Y, Espadaler-Mazo J, Huedo P, Aguiló M, et al. Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women. J Med Food. 2024;27:720. 10.1089/jmf.2023.k.0320
- Kwak YK, Daroczy K, Colque P, Kühn I, Möllby R, et al. Persistence of Lactobacilli in Postmenopausal Women - A Double-Blind, Randomized, Pilot Study. Gynecol Obstet Invest. 2017;82:144. 10.1159/000446946
- Bisanz JE, Seney S, McMillan A, Vongsa R, Koenig D, et al. A systems biology approach investigating the effect of probiotics on the vaginal microbiome and host responses in a double blind, placebo-controlled clinical trial of post-menopausal women. PLoS One. 2014;9:e104511. 10.1371/journal.pone.0104511
- Parma M, Dindelli M, Caputo L, Redaelli A, Quaranta L, et al. The role of vaginal Lactobacillus Rhamnosus (Normogin®) in preventing Bacterial Vaginosis in women with history of recurrences, undergoing surgical menopause: a prospective pilot study. Eur Rev Med Pharmacol Sci. 2013;17:1399.
- Petricevic L, Unger FM, Viernstein H, Kiss H. Randomized, double-blind, placebo-controlled study of oral lactobacilli to improve the vaginal flora of postmenopausal women. Eur J Obstet Gynecol Reprod Biol. 2008;141:54. 10.1016/j.ejogrb.2008.06.003
- Reid G, Burton J, Hammond JA, Bruce AW. Nucleic acid-based diagnosis of bacterial vaginosis and improved management using probiotic lactobacilli. J Med Food. 2004;7:223.
