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SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 19 Reviews
8.8
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 120
Amount Per Serving
%DV
Alpha Lipoic Acid
600 mg
*
Top Medical Research Studies
8
Alpha-lipoic acid enhances wound healing
Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model.
Directly addresses diabetes treatment
We aimed to understand how alpha-lipoic acid (LA) affects wound healing in diabetic conditions. The study involved five groups of mice: healthy controls, wounded healthy mice, wounded diabetic mice, and two groups of wounded diabetic mice treated with different doses of LA for 14 days.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Read More
7
Alpha-Lipoic Acid reduces AGEs
Alpha-Lipoic Acid Treatment Reduces the Levels of Advanced End Glycation Products in Type 2 Diabetes Patients with Neuropathy.
Direct effect on diabetes treatment
We explored the potential benefits of alpha-lipoic acid (ALA) for those with type 2 diabetes (T2DM) and nerve complications, known as neuropathy. In our study, we focused on how ALA affects advanced end glycation products (AGEs), which are harmful compounds that can worsen the condition by damaging blood vessels and nerve tissues.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Read More
8
Alpha-lipoic acid enhances wound healing
Multifunctional hyaluronic acid microneedle patch enhances diabetic wound healing in diabetic infections.
Combines LA with peptide treatment.
We set out to explore how alpha-lipoic acid (LA) could help in the healing of diabetic wounds, which often struggle to heal due to a mix of factors like high blood sugar and infections. In our investigation, we combined LA with a specialized peptide using a unique self-assembly process that didn’t require extra help from outside sources.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
Read More
Most Useful Reviews
9.5
Manages neuropathy
I purchased this for my 87-year-old mother with diabetes. Doctors recommended alpha-lipoic acid to help her manage diabetic neuropathy. I found it much cheaper to buy online. It significantly alleviates her symptoms and helps lower her blood sugar levels, which may require adjustment of her medications.
Read More
9.5
Metabolism regulation
This medicine normalises metabolism between tissue cells and organs, aiding in reducing blood glucose levels and enhancing glucose absorption by liver cells. It helps overcome insulin resistance and regulates carbohydrate and fat metabolism, while also lowering "bad" cholesterol levels. It normalises liver function and improves nerve tissue conductivity. Lipoic acid supports weight loss by accelerating metabolism, but it is effective only when combined with diet and exercise. It also alleviates symptoms of diabetes, such as altered skin sensitivity, burning, and numbness.
Read More
8.8
Aging prevention
Alpha-lipoic acid is a daily support for my husband and me. At over 50, we require additional aids for an active lifestyle. Its antioxidant properties protect our brain, liver, and blood vessels from damage while regulating blood sugar and improving metabolism. The product’s price-to-quality ratio meets our needs perfectly.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
8
Alpha-lipoic acid enhances wound healing
Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model.
Directly addresses diabetes treatment
We aimed to understand how alpha-lipoic acid (LA) affects wound healing in diabetic conditions. The study involved five groups of mice: healthy controls, wounded healthy mice, wounded diabetic mice, and two groups of wounded diabetic mice treated with different doses of LA for 14 days.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Read More
8
Alpha-lipoic acid enhances wound healing
Multifunctional hyaluronic acid microneedle patch enhances diabetic wound healing in diabetic infections.
Combines LA with peptide treatment.
We set out to explore how alpha-lipoic acid (LA) could help in the healing of diabetic wounds, which often struggle to heal due to a mix of factors like high blood sugar and infections. In our investigation, we combined LA with a specialized peptide using a unique self-assembly process that didn’t require extra help from outside sources.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
Read More
7
Alpha-Lipoic Acid reduces AGEs
Alpha-Lipoic Acid Treatment Reduces the Levels of Advanced End Glycation Products in Type 2 Diabetes Patients with Neuropathy.
Direct effect on diabetes treatment
We explored the potential benefits of alpha-lipoic acid (ALA) for those with type 2 diabetes (T2DM) and nerve complications, known as neuropathy. In our study, we focused on how ALA affects advanced end glycation products (AGEs), which are harmful compounds that can worsen the condition by damaging blood vessels and nerve tissues.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8.8
9.5
Metabolism improvement
Alpha-lipoic acid was prescribed by my son’s endocrinologist for managing his type 2 diabetes. It positively affects fat and glucose metabolism, enhancing insulin sensitivity and lowering blood glucose levels. We've noticed significant improvements in his overall health and weight.
Read More
9.5
Supports diabetes treatment
Excellent alpha-lipoic acid supplement! The jar contains a convenient dosage of comfortable-sized capsules. The product’s quality is exceptional and highly beneficial for those managing diabetes.
9.5
Manages neuropathy
I purchased this for my 87-year-old mother with diabetes. Doctors recommended alpha-lipoic acid to help her manage diabetic neuropathy. I found it much cheaper to buy online. It significantly alleviates her symptoms and helps lower her blood sugar levels, which may require adjustment of her medications.
Read More
9.5
Essential for diabetes
This supplement is crucial for treating type 2 diabetes. It’s a regular purchase for my mother upon her doctor’s recommendation and effectively relieves her diabetic neuropathy symptoms.
9.5
Metabolism regulation
This medicine normalises metabolism between tissue cells and organs, aiding in reducing blood glucose levels and enhancing glucose absorption by liver cells. It helps overcome insulin resistance and regulates carbohydrate and fat metabolism, while also lowering "bad" cholesterol levels. It normalises liver function and improves nerve tissue conductivity. Lipoic acid supports weight loss by accelerating metabolism, but it is effective only when combined with diet and exercise. It also alleviates symptoms of diabetes, such as altered skin sensitivity, burning, and numbness.
Read More
