Products best matching Diabetes

Zinc

9
Zinc alleviates diabetic muscle atrophy
Our investigation aimed to understand how zinc affects muscle atrophy in diabetes, a serious complication that leads to muscle loss. Using diabetes-induced mice, we treated them with zinc sulfate for six weeks and observed notable improvements in their muscle condition.

We conducted various analyses to evaluate the impact of zinc on autophagy—the process that helps manage muscle mass. The results were promising; zinc appeared to enhance muscle recovery by regulating specific molecular pathways connected to muscle health.

Additionally, our in vitro studies with diabetic muscle cells revealed similar results, with zinc supplementation proving beneficial in reducing excessive autophagy. Overall, this suggests that incorporating zinc into treatment plans could be a promising approach to counteract muscle deterioration in diabetic patients.
8.8
Immune system support
Most Useful Review
Zinc is essential for DNA synthesis, wound healing, and hormonal balance. It's crucial for proper immune function and can help prevent colds and other infections. Zinc deficiency can lead to frequent illnesses and has been linked to diabetes. Older adults often suffer from insufficient zinc, which can impact healing and immunity. It’s vital for overall health and well-being.

Enzymes

7
Nattokinase shows promise in diabetes
We explored how nattokinase (NK), a naturally occurring enzyme with anti-inflammatory and fibrinolytic effects, influences diabetes in a study using diabetic rats. Specifically, we focused on its potential to mitigate the harmful effects of diabetes, particularly in relation to blood glucose levels, plasma proteins, and inflammation.

In our experiment, we divided STZ-induced diabetic rats into three groups: a control group on a basic diet, a low-NK diet group, and a high-NK diet group. Over 14 days, we noticed that the high-NK diet significantly reduced glycogen buildup in the renal tubules and lowered certain inflammatory markers, specifically C-reactive protein (CRP) levels, by day 14. Surprisingly, while significant improvements were noted in the inflammatory response, the high NK diet did not lead to reductions in blood glucose levels.

It seems that the beneficial effects of NK in terms of preventing additional complications in diabetes are distinct from its impact on blood sugar control. The results suggest that NK may play a crucial role in decreasing inflammation and tissue damage without directly affecting glucose levels. Yet, it's unclear whether these positive outcomes stem from the NK itself or from the breakdown products created during digestion.
9.5
Health improvement
Most Useful Review
After extensive research, I bought this for my 55-year-old father who has diabetes, blood pressure issues, and kidney stones. He reports that it's wonderful and his health has improved. I'm thankful for this product and IHerb’s excellent quality.

Folic Acid

8
Folate may improve diabetes control
We examined the impact of folate, a water-soluble vitamin, on glycemic control and insulin resistance in individuals with type 2 diabetes. By systematically reviewing various studies, we uncovered that supplementing with folic acid could enhance insulin sensitivity.

Our analysis included a range of systematic reviews and meta-analyses focusing on the effects of different water-soluble vitamins, like B-1, B-3, biotin, B-9 (folate), and vitamin C. The findings highlighted that vitamin C also shows positive outcomes in managing blood sugar levels, but we observed that folic acid stood out in its ability to combat insulin resistance effectively.

Overall, while folic acid supplementation appears promising, we emphasized the need for further high-quality randomized controlled trials. This will help solidify our understanding and ensure that we can rely on folate as an effective treatment option for diabetes management.
9.5
Enhances alertness
Most Useful Review
The best around! Having PCOS, Type 2 diabetes, and cholesterol, I often experience brain fog. However, this folic acid has kept me alert for over a year. It's easy to swallow with breakfast and has no aftertaste, making it a daily essential.

L Taurine

8
Cornel iridoid glycosides effective for diabetes
We delved into the effects of cornel iridoid glycosides (CIG) on type 2 diabetes using a rat model. After inducing diabetes with a high-fat diet and streptozotocin, we examined various health indicators and conducted detailed metabolomic analyses of serum and urine.

Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
9.5
Stabilises blood sugar
Most Useful Review
I appreciate taurine for stabilising sugars in diabetes. It prevents surges and has improved my health for six months. It does not raise blood pressure, so I take it without worry.

Lecithin

9
Wound gels aid diabetic ulcer healing
We explored a novel approach to wound care for a 65-year-old woman struggling with a persistent diabetic foot ulcer. After a year of unsuccessful healing with standard treatments, we compounded two gel formulations: one with phenytoin and misoprostol, and another with nifedipine in a Pluronic lecithin organogel.

The treatment showed promising results with significant healing within 8 weeks, leading to complete closure in 17 weeks. This case suggests that specialized wound gels could be beneficial for patients with hard-to-treat diabetic foot ulcers.
8.3
Indispensable daily use
Most Useful Review
The drug is excellent and essential for daily use! Although the capsules are large and somewhat uncomfortable to swallow, I have no other complaints. Lecithin is a crucial fuel for the body and a component of cell membranes. It strengthens the nervous system, liver, and brain while regulating blood cholesterol and sugar levels, thus reducing external insulin needs in diabetes.

Inositol

8
D-Pinitol and ice plant benefits
We explored the effects of ice plant extract and its compound D-pinitol on insulin secretion and blood sugar levels in diabetic rats. By utilizing the glucose-stimulated insulin secretion test and measuring various insulin-related factors, we discovered that both substances significantly boosted insulin secretion.

Additionally, ice plant extract helped reduce weight gain and improved glucose tolerance. These findings suggest that ice plant and D-pinitol could serve as beneficial functional foods for managing diabetes and supporting insulin signaling in the body.
9.3
Effective for diabetes
Most Useful Review
This remedy is effective for managing diabetes and insulin resistance, particularly when taken with Berberine. I have found it to enhance the overall outcome of my treatment.

Ubiquinol Coq10

8
Mitochondrial cocktail shows promise
We aimed to understand how a combination of melatonin, nicotinamide mononucleotide (NMN), and ubiquinol could provide heart protection during episodes of reduced blood supply, known as ischemia/reperfusion (I/R) injury, especially in older rats with diabetes.

Our study involved male Wistar rats, aged between 22 and 24 months, that were induced with type-2 diabetes through a combination of a high-fat diet and low-dose streptozotocin. We carefully organized the rats into different groups to receive various combinations of treatments, evaluating their heart health after inducing I/R through a temporary blockage of blood supply.

The results showed that the combined treatment notably improved heart function and reduced damage from I/R injury. Not only did this trio enhance mitochondrial function, but it also increased the expression of important genes related to mitochondrial health.

While we didn't isolate the effects of ubiquinol alone, the promising outcomes associated with this mitochondrial cocktail suggest it could be beneficial for heart protection, particularly in older diabetic patients.
9.5
Hypertension and diabetes support
Most Useful Review
I recommend this product to all hypertensive patients on a continuous basis. It’s also beneficial for type 2 diabetes, at a dosage of 400 mg per day. It truly is a great product.

Omega 3 Fish Oil

We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.

Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
8.8
Positive mood enhancement
Most Useful Review
Excellent value for Omega-3! I take it for diabetes and find it boosts my mood. It's crucial for our bodies since we can't produce it ourselves. Omega-3 has numerous benefits, including reducing harmful fats in blood, aiding mental health, and supporting heart function. I recommend this supplement for anyone, especially for sports and overall well-being.

Selenium

9
Selenium's role in diabetes treatment
We sought to understand how selenium, when combined with taxifolin, might improve treatment options for diabetes mellitus. The focus was on creating selenized liposomes, or Tax-Se@LPs, that would enhance the delivery and effectiveness of taxifolin, a natural compound known for its potential health benefits.

Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.

Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
9.5
Boosts immune system
Most Useful Review
Selenium is vital for cancer protection and immunity against viruses. It aids pancreatic cell growth and improves glucose absorption, essential for managing diabetes by reducing insulin resistance. This mineral is best absorbed with fat-soluble vitamins A, D, and E, and it’s crucial for synthesising thyroid hormones.

Alpha Lipoic Acid

We explored the potential benefits of alpha-lipoic acid (ALA) for those with type 2 diabetes (T2DM) and nerve complications, known as neuropathy. In our study, we focused on how ALA affects advanced end glycation products (AGEs), which are harmful compounds that can worsen the condition by damaging blood vessels and nerve tissues.

Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.

We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.

Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
9.5
Maintains healthy sugar
Most Useful Review
I assisted a type 2 diabetic patient who had not taken medications. His cumulative score dropped from 8 to 6 within three months, thanks to adding Ceylon cinnamon and chromium while avoiding bread. With a healthy diet, this regimen can potentially reverse diabetes.

Elderberry Sambucus

8
Vitamin C improves diabetes control
We examined the effects of vitamin C supplementation on diabetes, focusing specifically on glycemic control and insulin resistance. Our analysis included a comprehensive review of fourteen systematic reviews and meta-analyses that assessed five different water-soluble vitamins: B-1, B-3, biotin, B-9 (folic acid), and C.

The findings revealed that vitamin C can significantly improve glycemic control in individuals with type 2 diabetes. We noticed reductions in fasting blood glucose levels and HbA1c, especially when supplementation lasted longer than 30 days. This is promising news for those managing diabetes, as it suggests that incorporating vitamin C could be beneficial.

Furthermore, we found that folic acid also plays a role in improving insulin resistance. However, there is a clear need for more well-designed randomized controlled trials to solidify these findings and develop a deeper understanding of the relationship between water-soluble vitamins and diabetes management.
9.5
Cold symptoms relief
Most Useful Review
I bought this for my son, who has a decade of experience managing diabetes. An endocrinologist recommended it. The results were swift; while on holiday, he took one lozenge daily, and by the second evening, his cold symptoms vanished. Typically, it takes longer to recover even with a high dose of vitamin C. I highly recommend this; it will now be a staple in our home first aid kit.

Quercetin

8
Quercetin inhibits glucose-regulating enzymes
We analyzed how quercetin, a key component of blueberry leaf polyphenols, influences diabetes by examining its effects on enzymes that regulate glucose levels. Our study utilized various techniques to understand the interactions between these compounds and the digestive enzymes α-amylase and α-glucosidase, both of which play significant roles in carbohydrate digestion.

During our research, we found that quercetin exhibited the most potent inhibitory effects on these enzymes. Specifically, it showed stronger action against α-glucosidase than α-amylase, which means it could potentially be more beneficial in managing blood sugar levels. Furthermore, we discovered that blueberry leaf polyphenols acted as mixed-type inhibitors, indicating that they hinder enzyme activity in multiple ways.

By evaluating the binding characteristics and the stability of the complexes formed between quercetin and the enzymes, we uncovered that α-glucosidase has a greater affinity for blueberry leaf compounds than α-amylase does. These molecular interactions suggest that quercetin might be a valuable addition to diabetes management strategies, particularly through its effects on glucose metabolism.

Overall, this research sheds light on how quercetin, derived from blueberry leaves, may help in controlling diabetes by effectively inhibiting key digestive enzymes.
7.5
Pain reduction
Most Useful Review
I appreciate that Quercetin and bromelain can be taken together. Quercetin possesses anti-inflammatory, antioxidant, and blood pressure regulating qualities, which I find beneficial. The combination helps with pain and inflammation, especially for diabetic conditions.

N Acetyl Cysteine Nac

9
Selenium's role in diabetes treatment
We sought to understand how selenium, when combined with taxifolin, might improve treatment options for diabetes mellitus. The focus was on creating selenized liposomes, or Tax-Se@LPs, that would enhance the delivery and effectiveness of taxifolin, a natural compound known for its potential health benefits.

Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.

Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
9.5
Helps type 1 diabetes
Most Useful Review
This supplement significantly aids my management of type 1 diabetes.

L Theanine

8
D-Pinitol and ice plant benefits
We explored the effects of ice plant extract and its compound D-pinitol on insulin secretion and blood sugar levels in diabetic rats. By utilizing the glucose-stimulated insulin secretion test and measuring various insulin-related factors, we discovered that both substances significantly boosted insulin secretion.

Additionally, ice plant extract helped reduce weight gain and improved glucose tolerance. These findings suggest that ice plant and D-pinitol could serve as beneficial functional foods for managing diabetes and supporting insulin signaling in the body.
8.8
Supports emotional stability
Most Useful Review
Works well! I gave it to my mother for emotional peace, and she found it beneficial. Her nerves have strengthened, and it has positively impacted her diabetes.

Vitamin B Complex

7
Annona muricata aids diabetes treatment
We explored the antidiabetic properties of Annona muricata leaf extract using a metabolomics approach on diabetes-induced rats. The study involved administering two doses of the extract to evaluate its impacts on metabolic profiles over four weeks.

Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
8.8
Improved blood counts
Most Useful Review
My husband has type 2 diabetes. He takes Glucofazhlong 1000 regularly, which has decreased his vitamin B12 and folic acid levels. He uses this product once daily under the tongue for three months with two-month intervals. His blood counts have improved, and his homocysteine levels have decreased. Additionally, he takes Q10, necessary for those with metabolic syndrome due to diabetes. I highly recommend it!

Calcium

7
Magnesium water enhances metabolic health
We explored the effects of magnesium (Mg) derived from deep ocean sources on adults dealing with hypertension, diabetes, or high cholesterol in a carefully designed clinical trial. Participants consumed either magnesium-enriched water (MEW) with 80 mg of Mg or a placebo containing only 6 mg of Mg daily for four weeks.

Throughout the study, we observed that MEW led to notable improvements in several health markers, such as body mass index (BMI), insulin levels, triglycerides, and fatigue. Interestingly, regardless of magnesium levels in the water, consuming more fluids helped reduce harmful substances in the body, like a byproduct of polycyclic aromatic hydrocarbons (PAHs) and an oxidative stress indicator called malondialdehyde.

Moreover, we noted significant changes in the gut microbiome of those drinking MEW, indicating a more diverse and balanced microbial environment. The presence of beneficial bacteria associated with magnesium intake suggested potential long-term health benefits, implying that MEW could play a role in preventing cardiovascular disease and type 2 diabetes.

Overall, it seems that magnesium-enriched water not only supports metabolic health but may also enhance gut flora, which is crucial for maintaining overall wellness.
9.5
Joint pain relief
Most Useful Review
I ordered it for my husband again. He has diabetes and takes these vitamins additionally. He reports less pain in his back and joints, so he is pleased with the results.

Vitamin Bs

9
Peptide hydrogel boosts islet transplantation
We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.

In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
8.8
Reduces blood sugar
Most Useful Review
Biotin is a vitamin, sometimes referred to as vitamin H or B7, essential for a healthy nervous system, skin, hair, and liver. It plays a crucial role in metabolising carbohydrates, fats, and proteins, converting food into energy. Biotin notably influences glucose production, as its levels inversely affect blood sugar; higher biotin levels lower blood sugar. Thus, biotin supplementation is recommended for those with diabetes. Additionally, adequate levels are vital for maintaining healthy hair and skin, with deficiencies potentially leading to issues such as hair loss and skin irritations.

Calcium Magnesium

7
Magnesium water enhances metabolic health
We explored the effects of magnesium (Mg) derived from deep ocean sources on adults dealing with hypertension, diabetes, or high cholesterol in a carefully designed clinical trial. Participants consumed either magnesium-enriched water (MEW) with 80 mg of Mg or a placebo containing only 6 mg of Mg daily for four weeks.

Throughout the study, we observed that MEW led to notable improvements in several health markers, such as body mass index (BMI), insulin levels, triglycerides, and fatigue. Interestingly, regardless of magnesium levels in the water, consuming more fluids helped reduce harmful substances in the body, like a byproduct of polycyclic aromatic hydrocarbons (PAHs) and an oxidative stress indicator called malondialdehyde.

Moreover, we noted significant changes in the gut microbiome of those drinking MEW, indicating a more diverse and balanced microbial environment. The presence of beneficial bacteria associated with magnesium intake suggested potential long-term health benefits, implying that MEW could play a role in preventing cardiovascular disease and type 2 diabetes.

Overall, it seems that magnesium-enriched water not only supports metabolic health but may also enhance gut flora, which is crucial for maintaining overall wellness.
9.5
Reduced muscle pain
Most Useful Review
Great product! I began taking it due to muscle pain from very low vitamin D. After a week, my muscle discomfort has nearly vanished. I feel energetic in the mornings. I also take selenium, vitamin E, D, zinc, and vitamins B and C. Magnesium is essential for diabetics; my 16-year-old daughter with type 1 diabetes takes one tablet before bed.

Magnesium

7
Magnesium water enhances metabolic health
We explored the effects of magnesium (Mg) derived from deep ocean sources on adults dealing with hypertension, diabetes, or high cholesterol in a carefully designed clinical trial. Participants consumed either magnesium-enriched water (MEW) with 80 mg of Mg or a placebo containing only 6 mg of Mg daily for four weeks.

Throughout the study, we observed that MEW led to notable improvements in several health markers, such as body mass index (BMI), insulin levels, triglycerides, and fatigue. Interestingly, regardless of magnesium levels in the water, consuming more fluids helped reduce harmful substances in the body, like a byproduct of polycyclic aromatic hydrocarbons (PAHs) and an oxidative stress indicator called malondialdehyde.

Moreover, we noted significant changes in the gut microbiome of those drinking MEW, indicating a more diverse and balanced microbial environment. The presence of beneficial bacteria associated with magnesium intake suggested potential long-term health benefits, implying that MEW could play a role in preventing cardiovascular disease and type 2 diabetes.

Overall, it seems that magnesium-enriched water not only supports metabolic health but may also enhance gut flora, which is crucial for maintaining overall wellness.
9.5
Diabetes controlled
Most Useful Review
Magnesium is vital for numerous bodily processes, including energy production and glucose assimilation. It calms the nervous system and aids in blood coagulation, offering anti-inflammatory benefits. I purchased this for my mother, who has type 2 diabetes, cardiac arrhythmia, and osteoporosis. After two purchases, we've noticed clearer results: her sugar levels have decreased, and her pulse rate stabilised. Magnesium also enhances calcium absorption, crucial for bone health. I trust Solgar for its quality, as magnesium citrate is better absorbed.

Vitamin D

8
Jamun juice vitamin D benefits
We sought to explore the effects of vitamin D on diabetes by fortifying jamun juice with this essential nutrient. Our approach involved creating a nanoemulsion of vitamin D using a low-temperature sonication method, which allowed us to enhance its presence in the juice.

The resulting drink, known as vitamin D fortified jamun juice (VDFJJ), showcased impressive nutritional attributes. It contained notable levels of total polyphenols and flavonoids, along with a high antioxidant activity of 94.2%.

When we examined its anti-diabetic potential, VDFJJ demonstrated significant inhibition of key enzymes related to carbohydrate digestion. Specifically, it showed effective inhibition of α-amylase and α-glucosidase, which play crucial roles in sugar absorption in the body.

Additionally, in our animal models that were deficient in vitamin D, we noted considerable improvements in various serum levels after four weeks of consuming the fortified juice. Results indicated increased levels of 25-OHD and calcium, among others, showcasing vitamin D's positive impact.

Overall, our nanoemulsion method appeared to boost vitamin D's solubility and bioavailability in a delicious beverage, paving the way for innovative solutions to tackle vitamin D deficiency while possibly aiding in diabetes management.
9.5
Vitamin D recommendation
Most Useful Review
It appears that vitamin D deficiency occurs even in sunny countries like Italy and Mexico. The optimal level of vitamin D is between 60-100 ng/ml, ideally measured by mass spectrometry. Many labs use ELISA, which underestimates levels. Vitamin D, being a steroid hormone, when deficient can lead to conditions including diabetes. After taking 10,000 IU of vitamin D daily, my levels rose from 18 to 111 ng/ml. I believe everyone should consider having it in their home remedies.

Astragalus

8
Astragaloside IV benefits diabetic nephropathy
We explored how astragaloside IV (AS-IV), a natural compound from the Astragalus root, impacts diabetic nephropathy (DN) and its symptoms. In our observations, AS-IV treatment showed promise in alleviating DN symptoms in mice, leading to improvements in several health markers, including body weight and kidney function indicators such as urine microalbumin and serum creatinine levels.

We noted that AS-IV seemed to reduce the progression of DN by lowering apoptosis, the process of programmed cell death that often contributes to kidney issues in diabetes. Our research revealed that AS-IV affects specific epigenetic modifications, particularly H3 lysine 4 monomethylation (H3K4me1), a mechanism tied to gene expression regulation.

Through our analyses, we pinpointed a gene, MAP4K3, which was elevated in DN conditions but decreased following AS-IV treatment. Silencing this gene led to reduced cell death in kidney cells exposed to high glucose levels, indicating that AS-IV might counteract the harmful effects of diabetes on kidney health. Overall, our findings suggest that AS-IV could play a significant role in protecting against diabetes-related kidney damage, offering a hopeful avenue for future therapies in diabetic nephropathy.
9.5
Protects against complications
Most Useful Review
A wonderful plant that protects the kidneys and retina from the complications associated with diabetes. Excellent quality and reasonable price. I highly recommend it.

Benfotiamine

We investigated the treatment of diabetic peripheral neuropathy (DPN), a common complication affecting many diabetes patients. Standard approaches focus on lifestyle changes and diabetes control, but symptomatic pain relief is often insufficient. Fortunately, recent studies highlight promising options like benfotiamine, which has shown effectiveness in reducing symptoms over time. The NATHAN 1 trial pointed to notable improvements in nerve function after four years. These findings suggest that additional, well-researched therapies could enhance DPN management and improve patient outcomes. Long-term studies are still needed to confirm their full potential.
9.5
Improved memory function
Most Useful Review
As I aged, I noticed my memory declining. Checking my thiamine levels showed they were low, especially on strict diets. Since taking Benfotiamine, I’ve experienced improvements in memory, sleep, and reduced irritability, making it easier to manage my diabetes. I suggest taking this complex as it also protects skin health.

Milk Thistle Silymarin

4
Silymarin shows limited diabetes impact
We reviewed several studies to understand how silymarin, a natural supplement, affects insulin resistance and sensitivity in individuals with diabetes. Our analysis showed that while silymarin can improve HOMA-IR levels slightly in type 2 diabetes patients, it did not significantly alter fasting insulin levels.

Interestingly, those with alcoholic cirrhosis experienced some benefits, but individuals with non-alcoholic fatty liver disease saw none. Overall, it appears that silymarin’s effects are limited, indicating a need for more robust research in this area.
8.8
Supports borderline diabetes
Most Useful Review
I have been using this product for many years and have noticed it is a great complement to the other products I take for my borderline diabetes. It has benefitted my liver and overall health, which is why I sometimes feel a slight twitch in the liver area after taking it.

Acetyl L Carnitine

We explored the potential benefits of carnitine supplementation in individuals with type 2 diabetes over a 12-week period. Our study involved 32 participants taking 2970 mg of L-carnitine daily, while we measured insulin sensitivity and acetylcarnitine levels in their muscles.

The results showed that carnitine treatment improved insulin sensitivity and increased acetylcarnitine concentrations in muscle. Additionally, there were hints of lower fasting plasma glucose levels and reduced liver fat content.

Although the benefits are promising, further research is essential to solidify these findings.
9.5
Lowered ALC level
Most Useful Review
I began taking two of these capsules while avoiding vinegar, and my diabetic A1C number dropped to 5.9, nearly in the normal range. I was absolutely overjoyed! I highly recommend these capsules, especially for those who have diabetes.

B12

8
B12 in multi-nutrient diabetes study
We explored how a combination of nutrients, including B12, impacts people with diabetic neuropathy. In a study with 73 individuals suffering from type 2 diabetes, participants were split into two groups: one received the combination of nutrients while the other received a placebo for six months.

Our findings revealed that this nutrient blend significantly improved pain levels, vibration perception, and B12 levels in participants. However, it’s important to note that the overall efficacy of B12 in this context is just part of a broader treatment approach rather than a standalone solution.
9.5
Pain relief experienced
Most Useful Review
I was struggling with severe back pain and could barely stand, but after taking one capsule post-breakfast, the pain diminished significantly within three days. This unexpected relief makes me extremely grateful. I suspect that, along with my diabetes medication, the B12 supplement has contributed to my recovery.

L Glutathione

4
Silymarin shows limited diabetes impact
We reviewed several studies to understand how silymarin, a natural supplement, affects insulin resistance and sensitivity in individuals with diabetes. Our analysis showed that while silymarin can improve HOMA-IR levels slightly in type 2 diabetes patients, it did not significantly alter fasting insulin levels.

Interestingly, those with alcoholic cirrhosis experienced some benefits, but individuals with non-alcoholic fatty liver disease saw none. Overall, it appears that silymarin’s effects are limited, indicating a need for more robust research in this area.
9.5
Enhances exercise performance
Most Useful Review
This product is very helpful in managing diabetes. If taken before exercising, it significantly enhances athletic performance.

Vitamins

8
Jamun juice vitamin D benefits
We sought to explore the effects of vitamin D on diabetes by fortifying jamun juice with this essential nutrient. Our approach involved creating a nanoemulsion of vitamin D using a low-temperature sonication method, which allowed us to enhance its presence in the juice.

The resulting drink, known as vitamin D fortified jamun juice (VDFJJ), showcased impressive nutritional attributes. It contained notable levels of total polyphenols and flavonoids, along with a high antioxidant activity of 94.2%.

When we examined its anti-diabetic potential, VDFJJ demonstrated significant inhibition of key enzymes related to carbohydrate digestion. Specifically, it showed effective inhibition of α-amylase and α-glucosidase, which play crucial roles in sugar absorption in the body.

Additionally, in our animal models that were deficient in vitamin D, we noted considerable improvements in various serum levels after four weeks of consuming the fortified juice. Results indicated increased levels of 25-OHD and calcium, among others, showcasing vitamin D's positive impact.

Overall, our nanoemulsion method appeared to boost vitamin D's solubility and bioavailability in a delicious beverage, paving the way for innovative solutions to tackle vitamin D deficiency while possibly aiding in diabetes management.
8.8
Improved eye health
Most Useful Review
Great! Both my eyes and skin benefit from this. I find it very effective as my eyes no longer dry out after prolonged use. My night vision has improved too. I've had diabetes for over 10 years, leading to inevitable fundus damage. However, with regular use of this vitamin A, I've managed to delay and reduce such damage. My skin appears smoother, unlike someone in their 50s. Occasionally, after continuous use, my skin feels itchy due to the high dose of 25,000 units per capsule. At that point, a short break helps. My genetic test pointed to a vitamin A metabolic disorder, hence the higher dosage. If in doubt, I'd suggest the average person stick to 10,000 units.

L Carnosine

8
Effects of L-carnosine on diabetes
In our exploration of how L-carnosine treatment affects diabetes, we focused on the interplay between detoxification enzymes, particularly glyoxalase 1 (GLO1) and aldehyde dehydrogenase 3A1 (ALDH3A1). We generated a unique combination of zebrafish that lacked both GLO1 and ALDH3A1 to better understand how their absence influences metabolic processes, especially dicarbonyl stress.

Through our observations, we found that the absence of these enzymes led to an increase in methylglyoxal (MG) and its harmful derivative MG-H1. This accumulation had dire consequences, resulting in impaired proteasome function, which in turn disrupted glucose control and spurred abnormal blood vessel growth in the eye. Encouragingly, we also noted that treatment with L-carnosine could reverse some of these detrimental effects, underscoring its potential role as a therapeutic intervention.

While we recognize that L-carnosine was part of a broader treatment landscape, its protective impact against the harmful accumulation triggered by enzyme loss highlights its significance. Future research could build on these findings to understand L-carnosine's specific contributions and clarify its effectiveness in diabetes management.
9.5
Effective for diabetes
Most Useful Review
Health must-have. One of the most effective supplements available. My mother deals with toxic stress and diabetes, and L-Carnosine is literally the answer to her overall health issues, also helping with age-related fatigue. Thanks, Now and iHerb.

Stevia

9.5
Indispensable for diabetics
Most Useful Review
Scientific evidence confirms that stevia is the best sugar substitute. It is non-toxic compared to synthetic sweeteners, has no side effects, tastes great, and is reasonably priced. Stevia is essential for those with diabetes and is digestion-friendly as it doesn’t require insulin. It does not impact blood sugar levels. I ordered it for my mother-in-law, who has diabetes. She uses it everywhere in place of sugar and has chosen it specifically for its lack of aftertaste. She loves this sugar substitute. I highly recommend buying it!
9.5
Best sugar substitute
Most Useful Review
Scientific evidence shows that stevia is currently the leading sugar substitute. It is non-toxic, has no side effects, tastes lovely, and is affordable. Essential for diabetics, stevia does not require insulin for digestion and will not raise blood sugar levels. I ordered it for my mother-in-law, who has diabetes. She uses it everywhere instead of sugar. I will order more for her satisfaction.

Xylitol

9.5
Long-term use
Most Useful Review
Excellent! I have been using it for almost two years, and many relatives and acquaintances with diabetes have started using this sugar.
9.5
Natural alternative
Most Useful Review
High quality! This excellent product offers a natural and healthy alternative to traditional sweeteners. Made with all-natural, organic ingredients, it serves as a safe option for those wishing to reduce sugar intake. The unique blend of natural xylitol does not spike blood sugar levels, making it ideal for people with diabetes or anyone keen to maintain a healthy weight.

Multivitamins

9.5
Energy boost noted
Most Useful Review
My mother, who has type 1 diabetes, has experienced significant improvements. Her skin has improved, and she has more energy and a better metabolism since using it.
9.5
Effective for control
Most Useful Review
It is true that it has a strong smell, and it does change with use, but I am completely satisfied with this product, which is excellent for regulating type 1 diabetes. I notice its immediate effect when taking a pill and monitoring my weight. I recommend it for both type 1 and type 2 diabetes patients. My mother, who is a type 2 diabetic, has also benefitted, as it helps lower her blood sugar and alleviates her associated bone pain. The ingredients are highly effective, making it worth repurchasing.

Potassium

9.5
Cardiovascular health
Most Useful Review
Recommended for the prevention of cardiovascular diseases, diabetes, and neuroses. Potassium contributes to healthy sleep and alleviates night leg cramps. A deficiency manifests as waking up at night. It is essential for optimal energy, nerve health, and physical endurance. Additionally, it regulates water balance, removes excess water, and helps normalise blood pressure. It improves oxygen supply to the brain. The best form is potassium citrate. If you found my review helpful, please click the thumbs up. I would appreciate it.
9.5
Helpful for mother
Most Useful Review
Fantastic! I buy this for my mother who suffers from diabetes, and it has greatly helped her. Highly recommended!

Ashwagandha

9.5
Stable blood sugar
Most Useful Review
I purchased ashwagandha for my mother, who previously used a compound formula. This herb is particularly effective at alleviating the dawn phenomenon in ketogenic type 2 diabetes patients. After using it for half a month, we observed, using a continuous blood glucose monitor, that her blood sugar stabilised below 4.5 mmol/L before breakfast at ten o'clock in the morning. I will continue to buy it.
9.5
Blood sugar lowering
Most Useful Review
Ashwagandha has demonstrated effectiveness in lowering blood sugar and fats. Some small clinical studies indicate that it helps reduce blood glucose and triglycerides (the most common type of fat in the blood). One study highlighted Ashwagandha’s blood sugar-lowering effects compared to medications prescribed for type 2 diabetes.

Ginkgo Biloba

9.5
Protects blood vessels
Most Useful Review
An excellent antioxidant, it protects blood vessels from damage in diabetes mellitus and improves blood flow. It is advisable to start with small doses, around 100 mg.
9.5
Stabilizes circulation
Most Useful Review
Due to diabetes and hypertension, I often experienced cold hands and feet during winter, which made work difficult. However, ever since I started taking Ginkgo, I feel comfortable throughout the winter. I highly recommend this product as it has significantly enhanced my working experience.

D Mannose

9.5
Keeps UTIs away
Most Useful Review
Now Foods D-Mannose capsules are a fantastic find! I was paying over $32 a bottle locally, so it's a relief to find them at such a low price on iHerb. This product is effective and helps prevent urinary tract infections, which I've experienced frequently since being diagnosed with diabetes in 2006. My order was processed swiftly and shipped the same day, making me a huge fan of iHerb!
9.5
Reduced UTIs significantly
Most Useful Review
I will never run out of D-Mannose! Since being diagnosed with diabetes, I experienced UTIs every couple of months despite medication. I managed to prevent them using cranberry and grape seed extract, but often resorted to antibiotics. After my sister-in-law recommended D-Mannose over two years ago, I've only had one UTI that I treated without antibiotics. I take one daily, increasing the dosage when needed.

Olive Leaf

10
Effective for diabetes
Most Useful Review
Olive leaf extract is scientifically proven to be an excellent antiviral and antioxidant. It prevents heart and vascular diseases, diabetes, and more. After COVID-19, I began using it to restore blood vessel elasticity, and the capsules I found are easier to take than liquids. I fully recommend it!
8.3
Proven diabetes aid
Most Useful Review
The effectiveness of olive leaves and oleuropein in lowering blood pressure and providing health benefits is proven. Their anti-inflammatory and antioxidant properties help fight diabetes and other serious diseases.

Turmeric Curcumin

9.5
Blood sugar decrease
Most Useful Review
Great curcumin. A sister I know took curcumin alongside her diabetes medication and saw her blood sugar levels finally drop to a safe level. The doctor may lower her medication at her next appointment if she continues with curcumin. Thank goodness!
9.5
Better health overall
Most Useful Review
I bought curcumin for my father with type 2 diabetes and hypertension. After two weeks of use, he reported feeling much better.

5 Htp

9.5
Mood improvement
Most Useful Review
I bought this for my 16-year-old niece who has type 1 diabetes, and her mood and temper have improved tremendously. Initially, her psychiatrist intended to prescribe medication, but after she started this product, the doctor concluded she did not need medication for the time being.
8.8
Reduced hunger cravings
Most Useful Review
Help Overweight Management. Those who have dieted know the stress of restricting nutrition, especially with the temptation of delicious carbohydrates. I love baking, but excess carbohydrates not only lead to weight gain, but also increase the risk of diabetes. 5-HTP is beneficial as it helps manage appetite. Derived from tryptophan, which our body does not produce, this supplement can significantly lower cravings for carbohydrates. A study showed that women taking 5-HTP alongside a low-calorie diet had fewer cravings. Start slowly from 50 mg to 500 mg per day and consult a doctor for larger doses. This supplement has helped me considerably, almost eliminating my evening hunger.

Garlic

9.5
Useful for heart health
Most Useful Review
Excellent! I've been using it for four years due to heart artery problems. This product is highly beneficial for those with heart disease, high blood pressure, diabetes, and elevated cholesterol levels.
8.8
Long-term benefits
Most Useful Review
I've used it for about four years and found it to be excellent and beneficial, particularly for individuals with heart conditions, diabetes, and high blood pressure.

Broccoli

9.5
Effective blood sugar control
Most Useful Review
My mother has type 2 diabetes, and BroccoMax has proven to be the best supplement for lowering her blood sugar. Since she began taking it, the difference has been significant and very noticeable.
8.8
Helps reduce toxins
Most Useful Review
This patented product has greatly assisted me in eliminating toxins. I purchased it for my mother, and it has significantly helped her manage diabetes while also reducing harmful oestrogen levels.

Probiotics

9.5
Beneficial for diabetes
Most Useful Review
I purchased these pills for my mother as she has diabetes, and due to their cranberry and probiotic content, they are effective against urinary tract infections. This is the second time I've bought them, and they've significantly benefited her. Everyone at home takes them to prevent infections, ensuring we drink enough water in winter. Highly recommended!
8.8
Lowers sugar levels
Most Useful Review
The benefits of cranberries are notable! Regular consumption enhances blood vessel health, lowers cholesterol, and reduces sugar levels in those with type 2 diabetes while combating insulin resistance. They also have potential antitumor properties.

B6 Pyridoxine

9.5
Normalises blood sugar
Most Useful Review
P-5-P is a form of vitamin B6 that must be replenished since it is water-soluble and quickly excreted. This vital nutrient aids metabolic processes and the assimilation of proteins and fats, positively affecting skin condition. Additionally, pyridoxine enhances nervous system health, combats depression, mitigates anxiety, and bolsters the immune system. It also helps regulate blood sugar levels, thus reducing the risk of diabetes.
8.8
Reduces diabetes risk
Most Useful Review
I take a course with magnesium and have a break for a couple of months. Pyridoxal phosphate, also known as P-5-P, is the active form of vitamin B-6 essential for normal body functions. It helps lower levels of glycosylated hemoglobin, crucial for the prevention of atherosclerosis and diabetes. P-5-P acts as a diuretic, reducing blood pressure in those with hypertension, thereby protecting the cardiovascular system. In cases of depression and anxiety, it boosts the production of norepinephrine and serotonin, enhancing mental and physical activity.

Cinnamon Herbs

9.5
Excellent glucose supplement
Most Useful Review
Brilliant! I bought this for my mother, who suffers from elevated glucose due to diabetes. It’s an excellent supplement for glucose regulation.
9.5
Helps diabetes significantly
Most Useful Review
Excellent! It has really helped my diabetes a lot!

Spirulina

9.5
Effective for diabetes
Most Useful Review
I bought it for my dad, who has type 2 diabetes. Remarkably, after three days, he felt energised, and his mood improved significantly. After a week, he stopped taking blood pressure medications as his sugar levels normalised. I had previously tried another brand without seeing such results, so I truly appreciate the efficacy of this spirulina product.
8.8
Neutral taste experience
Most Useful Review
I was pleasantly surprised by the quality of spirulina. It's a fantastic dietary supplement for elderly individuals with diabetes. After three weeks, I noticed its effects, and the taste is neutral, making it easy to consume.

L Glycine

9.5
Glycine aids health
Most Useful Review
I consistently buy this excellent glycine. As a type 1 diabetic, it helps maintain my glycated hemoglobin levels, reduces inflammation, and enhances my overall well-being, even when my sugar levels are high. This product dissolves quickly under my tongue or can be added to food and drinks as a sweetener, though I avoid high doses. It’s truly the best solution in terms of cost and quality I've come across, and I recommend it highly!
9.5
Enhances healing process
Most Useful Review
Glycine is remarkable as it combines with NAC to restore glutathione and improve brain function without impacting memory. It relaxes and enhances sleep, and is effective for diabetes management while also aiding in the formation of red blood cells and hemoglobin. Taking 15g daily significantly reduces sugar levels. The combination of glycine and NAC is beneficial for lowering blood pressure and improving mitochondrial health. I find that it slows disease progression and accelerates healing.

Apple Cider Vinegar

8.8
Insulin management
Most Useful Review
Increased dosage can reduce the insulin index of various products. I take it at every meal to lower elevated blood insulin and prevent type 2 diabetes. The convenience of apple cider vinegar in capsule form makes it easy to carry.
8
Convenient intake
Most Useful Review
I normally dilute the undiluted solution of apple cider vinegar with water because of diabetes, but it was somewhat cumbersome. This capsule form is easier to take and quite beneficial.

Rutin

9.5
Liver protection
Most Useful Review
Rutin safeguards the stomach from gastritis and the liver from non-alcoholic fatty liver disease. It reduces liver enzyme levels, and can even reverse insulin resistance linked to type 2 diabetes mellitus. Notably, the optimal dose is cited as 5 mg per kg of body weight once a week.
9.5
Prevent insulin resistance
Most Useful Review
Rutin cannot be synthesized by the human body, making it essential to consume foods rich in this compound, such as chokeberries, black currants, and citrus fruits, or to take supplements. It has significant health benefits, including reducing protein glycation, systemic inflammation, and aiding in the prevention of type 2 diabetes, alongside reversing insulin resistance.

Fiber

9.5
Diabetes management success
Most Useful Review
Eat what you like, just take the pills (usually two) with food; in my experience, it takes three months to work, and then the weight just falls off—without any diet changes. However, if you have diabetes, be cautious as your sugar levels mustn't drop too low. Do ensure you drink plenty of water and take them with food. My husband has lost 60 pounds in a month, and I lost over 80 pounds in three months without changing my diet. You must carry these pills with you and stay committed. They jump-start your metabolism and consume excess sugar, making it a total win. I went from 189 to 106 pounds, eliminated blood pressure and cholesterol medications, and am no longer borderline diabetic.
9.5
Energised feeling
Most Useful Review
I purchased the same product in London for more than double the price here and found it effective for my diabetes. I take two capsules daily, and saw results from day two. I felt energised and am continually improving. I recommend trying it as the price is very reasonable.

Resveratrol

9.5
Reduces oxidative stress
Most Useful Review
Resveratrol is effective for diabetes as it reduces excessive sorbitol accumulation, thereby alleviating oxidative stress that harms cells and hinders insulin resistance.
9.5
A good drug
Most Useful Review
Resveratrol enhances insulin sensitivity and combats oxidative stress. I found it effective in alleviating the condition of diabetes patients while preventing complications. It’s truly a valuable drug.

Beta Glucan

8.8
Positive diabetes outlook
Most Useful Review
About a year ago, our son was diagnosed with type 1 diabetes, leading to constant insulin injections and frequent blood sugar monitoring. Doctors indicated it was not curable. Thankfully, his overall condition remains good, with slightly elevated cholesterol but normal readings otherwise. We've been on medication for two months, and I'm optimistic about the results improving further; belief is vital!
7.5
Diabetes improvement noted
Most Useful Review
I believe this product has helped with my diabetes. I'm inclined to wait longer for further results, but my diabetes levels have shown improvement after use.

Cat Claw

8.8
Effective for diabetes
Most Useful Review
To assist with diabetes, Cat's claw proves beneficial for allergies, viral infections, and various inflammatory processes. It has a powerful immunostimulatory effect in cancer, activating the body's defence mechanisms. Today, it stabilises hormonal backgrounds, treats peptic ulcers, and strengthens the body's immunity. Cat's claw also aids diabetes, arthritis, prostatitis, and various gynaecological diseases. It is effective against intoxication effects from drugs, chemotherapy, and radiation therapy. I use it for prevention as I have diabetes.
9.5
Improves nerve pain
Most Useful Review
Having used this product for a week now, the needle-like pain in my feet and thighs has vanished. I suffered from heat in my feet, which disrupted my sleep and made sitting painful. Using Cat's claw and Panax ginseng, I’m improving daily and hope to reclaim my former self. iHerb has provided excellent service. I ordered two more and highly recommend it to others with similar issues.

Prebiotic Fiber Inulin

9.5
Prevents diabetes
Most Useful Review
To prevent diabetes, I take inulin before meals as it moderates sugar absorption, aiding in maintaining stable levels.
8.3
Metabolism improvement
Most Useful Review
Start with small doses. Inulin enhances carbohydrate and lipid metabolism, normalises blood sugar levels, and promotes metabolic activation and fat burning, making it effective for treating both type 1 and 2 diabetes.