Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.6
USERS' SCORE
Good
Based on 25 Reviews
8.7
Supplement Facts
Serving Size: 5 Drops
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
L.reuteriDSM 17938(L. reuteriProtectis®)
100 million CFU
†
Top Medical Research Studies
9.5
We explored how Lactobacillus reuteri affects regurgitation and gastric emptying in infants suffering from gastroesophageal reflux. By following 42 infants for 30 days, with some receiving the probiotic and others a placebo, we witnessed notable results.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
Read More
9
We conducted a study to see if Lactobacillus reuteri DSM 17938, given to newborns for their first three months, could lower rates of colic, reflux, and constipation.
In our trial, involving 589 infants across nine neonatal units in Italy, we compared the effects of the probiotic to a placebo. Parents kept detailed logs of various health issues, including regurgitation and crying episodes.
The results showed that using Lactobacillus reuteri reduced these gastrointestinal problems and the associated socioeconomic burden. It’s promising news for parents facing these challenges!
In our trial, involving 589 infants across nine neonatal units in Italy, we compared the effects of the probiotic to a placebo. Parents kept detailed logs of various health issues, including regurgitation and crying episodes.
The results showed that using Lactobacillus reuteri reduced these gastrointestinal problems and the associated socioeconomic burden. It’s promising news for parents facing these challenges!
Read More
9
We investigated the effects of Lactobacillus reuteri DSM 17938 on feeding tolerance and growth in preterm infants. In a study with 114 formula-fed infants, we divided participants into two groups—one receiving the probiotic and the other receiving no treatment.
Results showed fewer reflux episodes in the group taking probiotics, along with quicker feeding tolerance and improved growth markers. However, no significant differences were observed in infection rates. Overall, Lactobacillus reuteri appears beneficial for feeding tolerance and growth in preterm infants.
Results showed fewer reflux episodes in the group taking probiotics, along with quicker feeding tolerance and improved growth markers. However, no significant differences were observed in infection rates. Overall, Lactobacillus reuteri appears beneficial for feeding tolerance and growth in preterm infants.
Read More
Most Useful Reviews
10
Restored my son's gut
129 people found this helpful
If your baby is fussy or has reflux, buy these drops now! My NICU baby suffered after being on IV antibiotics, but after trying a pricier probiotic with no success, I switched to this one. It worked wonders for my son, alleviating his fussiness and making his reflux significantly better. Highly recommend!
Read More
7.5
Great for reflux
60 people found this helpful
These are a gift from heaven! Initially sceptical about probiotics for my 4-month-old due to the marketing hype, I decided to try since L. reuteri is present in some mothers' breast milk. This was the best decision! My little one previously suffered from terrible gas and reflux, which led to slow weight gain. After using these, the spitting up has significantly decreased, and he's now more comfortable, pooping normally.
Read More
9
Significant improvement
17 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby suffered from reflux, but after using these drops, his condition improved drastically. They worked just as well as the pricier version I initially used. I can’t recommend them highly enough.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.6
- All Researches
9.5
We explored how Lactobacillus reuteri affects regurgitation and gastric emptying in infants suffering from gastroesophageal reflux. By following 42 infants for 30 days, with some receiving the probiotic and others a placebo, we witnessed notable results.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
Read More
9
We investigated the effects of Lactobacillus reuteri DSM 17938 on feeding tolerance and growth in preterm infants. In a study with 114 formula-fed infants, we divided participants into two groups—one receiving the probiotic and the other receiving no treatment.
Results showed fewer reflux episodes in the group taking probiotics, along with quicker feeding tolerance and improved growth markers. However, no significant differences were observed in infection rates. Overall, Lactobacillus reuteri appears beneficial for feeding tolerance and growth in preterm infants.
Results showed fewer reflux episodes in the group taking probiotics, along with quicker feeding tolerance and improved growth markers. However, no significant differences were observed in infection rates. Overall, Lactobacillus reuteri appears beneficial for feeding tolerance and growth in preterm infants.
Read More
9
We explored how a specially formulated infant formula containing Lactobacillus reuteri (DSM 17938) affects regurgitation and gastric motility in babies struggling with functional regurgitation.
In a well-structured randomized controlled trial, infants took a test formula for four weeks, allowing us to measure changes in their gastric emptying rate and regurgitation frequency.
The results were promising: infants on the test formula experienced a significant decrease in daily regurgitations compared to the control group, highlighting the potential benefits of this formulation for managing reflux in infants.
In a well-structured randomized controlled trial, infants took a test formula for four weeks, allowing us to measure changes in their gastric emptying rate and regurgitation frequency.
The results were promising: infants on the test formula experienced a significant decrease in daily regurgitations compared to the control group, highlighting the potential benefits of this formulation for managing reflux in infants.
Read More
9
We conducted a study to see if Lactobacillus reuteri DSM 17938, given to newborns for their first three months, could lower rates of colic, reflux, and constipation.
In our trial, involving 589 infants across nine neonatal units in Italy, we compared the effects of the probiotic to a placebo. Parents kept detailed logs of various health issues, including regurgitation and crying episodes.
The results showed that using Lactobacillus reuteri reduced these gastrointestinal problems and the associated socioeconomic burden. It’s promising news for parents facing these challenges!
In our trial, involving 589 infants across nine neonatal units in Italy, we compared the effects of the probiotic to a placebo. Parents kept detailed logs of various health issues, including regurgitation and crying episodes.
The results showed that using Lactobacillus reuteri reduced these gastrointestinal problems and the associated socioeconomic burden. It’s promising news for parents facing these challenges!
Read More
8
We investigated how Vitamin D3 affects inflammation caused by reflux esophagitis—a condition where stomach acid irritates the esophagus. In our study, we used 70 male rats, dividing them into groups to examine the impact of Vitamin D3 at different doses on inflammation levels.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
Read More
User Reviews
USERS' SCORE
Good
Based on 25 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Restored my son's gut
129 people found this helpful
If your baby is fussy or has reflux, buy these drops now! My NICU baby suffered after being on IV antibiotics, but after trying a pricier probiotic with no success, I switched to this one. It worked wonders for my son, alleviating his fussiness and making his reflux significantly better. Highly recommend!
Read More
7.5
Great for reflux
60 people found this helpful
These are a gift from heaven! Initially sceptical about probiotics for my 4-month-old due to the marketing hype, I decided to try since L. reuteri is present in some mothers' breast milk. This was the best decision! My little one previously suffered from terrible gas and reflux, which led to slow weight gain. After using these, the spitting up has significantly decreased, and he's now more comfortable, pooping normally.
Read More
9
Significant improvement
17 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby suffered from reflux, but after using these drops, his condition improved drastically. They worked just as well as the pricier version I initially used. I can’t recommend them highly enough.
Read More
9
Reduced fussiness
11 people found this helpful
Great for colic and food allergies! My daughter faced severe colic and food allergies at just four weeks old. After trying reflux medications without success, I switched to a corn-free formula and introduced this product. Within days, her crying reduced drastically, and now she passes gas without difficulty. This product has made a remarkable difference!
Read More
9
Life-changing results
7 people found this helpful
Worth every penny!! I rarely write reviews, but this product is amazing! After a doctor suggested probiotics for my baby's diarrhoea, it transformed everything. My exclusively breastfed 6-month-old was previously fussy from reflux, but since using this probiotic, she has improved dramatically. I cannot recommend it highly enough; it truly changed our lives.
Read More
Frequently Asked Questions
7.5
Easier feeding
1 people found this helpful
My baby had colic and reflux, making feeding a challenge. Since using this probiotic, he drinks milk without struggle. I noticed a difference after about four days of use.
9
Significant improvement
6 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby had reflux and was in discomfort. After using these drops, his symptoms improved greatly. They are equally effective as the more expensive option I tried. I highly recommend these.
9
Effective treatment
I started using this on my infant due to severe reflux. Initially unsure about the cost, I saw positive results. After pausing, her symptoms worsened, but upon resuming the drops, her health improved quickly.
9
Significant improvement
17 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby suffered from reflux, but after using these drops, his condition improved drastically. They worked just as well as the pricier version I initially used. I can’t recommend them highly enough.
9
Significant improvement
2 people found this helpful
I’m so grateful for Biogaia Probiotics! After trying this, my baby’s reflux and colic improved significantly. The quality is excellent, and she tolerates the mild taste well. I highly recommend this product for any parent facing similar issues.
8
L. reuteri improves infant reflux symptoms
We aimed to assess how Lactobacillus reuteri NCIMB 30351 affects infants with gastroesophageal reflux and other gastrointestinal issues. In a controlled study with 90 infants, we found that those receiving L. reuteri experienced fewer episodes of regurgitation, reduced crying time, and improved bowel movements compared to those with a placebo.
Additionally, the probiotic showed a positive impact on gut microbiota while inhibiting harmful bacteria. With no reported adverse effects, L. reuteri appears to be a safe and effective option for managing reflux and related symptoms in infants.
Additionally, the probiotic showed a positive impact on gut microbiota while inhibiting harmful bacteria. With no reported adverse effects, L. reuteri appears to be a safe and effective option for managing reflux and related symptoms in infants.
9.5
We explored how Lactobacillus reuteri affects regurgitation and gastric emptying in infants suffering from gastroesophageal reflux. By following 42 infants for 30 days, with some receiving the probiotic and others a placebo, we witnessed notable results.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue.
8
We investigated how Vitamin D3 affects inflammation caused by reflux esophagitis—a condition where stomach acid irritates the esophagus. In our study, we used 70 male rats, dividing them into groups to examine the impact of Vitamin D3 at different doses on inflammation levels.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time.
9
We explored how a specially formulated infant formula containing Lactobacillus reuteri (DSM 17938) affects regurgitation and gastric motility in babies struggling with functional regurgitation.
In a well-structured randomized controlled trial, infants took a test formula for four weeks, allowing us to measure changes in their gastric emptying rate and regurgitation frequency.
The results were promising: infants on the test formula experienced a significant decrease in daily regurgitations compared to the control group, highlighting the potential benefits of this formulation for managing reflux in infants.
In a well-structured randomized controlled trial, infants took a test formula for four weeks, allowing us to measure changes in their gastric emptying rate and regurgitation frequency.
The results were promising: infants on the test formula experienced a significant decrease in daily regurgitations compared to the control group, highlighting the potential benefits of this formulation for managing reflux in infants.
8
This study explored the effects of Lactobacillus reuteri on regurgitation in breastfed infants. We closely monitored 40 infants, randomly assigning them to receive either L. reuteri or a placebo for four weeks.
By the end of the trial, those treated with the probiotic showed a significant decrease in daily regurgitation episodes, while only a few in the placebo group needed help for gastrointestinal issues.
Overall, our findings suggest that early administration of L. reuteri can be beneficial for preventing regurgitation in infants during their first month.
By the end of the trial, those treated with the probiotic showed a significant decrease in daily regurgitation episodes, while only a few in the placebo group needed help for gastrointestinal issues.
Overall, our findings suggest that early administration of L. reuteri can be beneficial for preventing regurgitation in infants during their first month.
References
- Wei J, Zhang J, Jiang Y, Lian T, Zhang P, et al. Elevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25 Dihydroxy Vitamin D3. In Vivo. 2023;37:79. doi:10.21873/invivo.13056
- Tyrsin OY, Tyrsin DY, Nemenov DG, Ruzov AS, Odintsova VE, et al. Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. Eur J Pediatr. 2024;183:2311. doi:10.1007/s00431-024-05473-y
- Cui X, Shi Y, Gao S, Xue X, Fu J. Effects of Lactobacillus reuteri DSM 17938 in preterm infants: a double-blinded randomized controlled study. Ital J Pediatr. 2019;45:140. doi:10.1186/s13052-019-0716-9
- Belei O, Olariu L, Dobrescu A, Marcovici T, Marginean O. Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?. J Neurogastroenterol Motil. 2018;24:51. doi:10.5056/jnm17059
- Indrio F, Riezzo G, Giordano P, Ficarella M, Miolla MP, et al. Effect of a Partially Hydrolysed Whey Infant Formula Supplemented with Starch and Lactobacillus reuteri DSM 17938 on Regurgitation and Gastric Motility. Nutrients. 2017;9. doi:10.3390/nu9111181
- Garofoli F, Civardi E, Indrio F, Mazzucchelli I, Angelini M, et al. The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants. Int J Food Sci Nutr. 2014;65:646. doi:10.3109/09637486.2014.898251
- Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168:228. doi:10.1001/jamapediatrics.2013.4367
- Indrio F, Riezzo G, Raimondi F, Bisceglia M, Filannino A, et al. Lactobacillus reuteri accelerates gastric emptying and improves regurgitation in infants. Eur J Clin Invest. 2011;41:417. doi:10.1111/j.1365-2362.2010.02425.x
