 Nordic Naturals, Prenatal DHA, 90 Soft Gels | | |
Vitamin D3 may aid inflammationElevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25 Dihydroxy Vitamin D3. We aimed to understand whether vitamin D3 can have a beneficial effect on reflux esophagitis (RE), a condition caused by stomach acid irritating the esophagus. To explore this, we conducted experiments on seventy male Sprague-Dawley rats, dividing them into groups to study both acute and chronic forms of RE. We treated some of these rats with varying doses of vitamin D3, while others did not receive this treatment, allowing us to compare differences in inflammation levels.
The results showed that the levels of important pro-inflammatory proteins—IL-1β, IL-6, and IL-8—were significantly elevated in the rats suffering from RE. However, when we treated the rats with vitamin D3, we observed a notable reduction in these inflammatory markers, but only in the acute RE group. Unfortunately, similar benefits were not evident in the chronic RE group, and vitamin D3 did not improve the overall condition of the esophagus on a structural level.
Interestingly, our histopathological examinations revealed varying degrees of esophageal damage, regardless of vitamin D3 treatment. While elevated serum calcium levels were noted following vitamin D3 treatment, this did not translate into improvements in chronic RE cases. Overall, our findings point to a potential protective role of vitamin D3 in early-stage reflux esophagitis, suggesting that it might help manage inflammation at the beginning of this condition. No reflux observed Most Useful Review 20 people found this helpful This is the only DHA I prescribe to my patients. It's clean, regulated, and vital for foetal brain and eye development in the third trimester. If you want a clever baby who meets milestones easily, buy this product. The small capsules are easy to swallow and cause minimal reflux. It's best taken with food for optimal absorption. |
 Solgar, Omega 3, EPA & DHA, Triple Strength, 950 mg, 100 Softgels | | |
Resolvin D1's role in GERD treatmentResolvin D1 attenuates acid-induced DNA damage in esophageal epithelial cells and rat models of acid reflux. We investigated the role of resolvin D1 (RvD1) in protecting esophageal epithelial cells from damage caused by acid reflux. Through exposure tests, we found that RvD1 could effectively block oxidative stress and DNA damage linked to acid exposure.
Notably, RvD1 not only reduced harmful reactive oxygen species but also enhanced the cell's ability to repair DNA damage, signaling a promising potential for treatment in patients with gastroesophageal reflux disease. However, we need more studies to confirm its benefits in clinical settings. No reflux Most Useful Review Excellent! Perfect! No reflux :) |
 Natrol, Omega-3 Fish Oil, Lemon, 1,000 mg, 150 Softgels | | |
Resolvin D1's role in GERD treatmentResolvin D1 attenuates acid-induced DNA damage in esophageal epithelial cells and rat models of acid reflux. We investigated the role of resolvin D1 (RvD1) in protecting esophageal epithelial cells from damage caused by acid reflux. Through exposure tests, we found that RvD1 could effectively block oxidative stress and DNA damage linked to acid exposure.
Notably, RvD1 not only reduced harmful reactive oxygen species but also enhanced the cell's ability to repair DNA damage, signaling a promising potential for treatment in patients with gastroesophageal reflux disease. However, we need more studies to confirm its benefits in clinical settings. Reflux improvement Most Useful Review 11 people found this helpful Changed my life. This product has been one of the best I've taken, aiding my digestion and joint issues. I had torn both my shoulder labrums, and this supplement has helped me recover to about 90%. Previously, I struggled with severe acid reflux, but now I can enjoy coffee without any problems. Excellent product! |
 Carlson, Wild Norwegian, Elite Omega-3 Gems®, Natural Lemon, 120 Soft Gels | | |
Resolvin D1's role in GERD treatmentResolvin D1 attenuates acid-induced DNA damage in esophageal epithelial cells and rat models of acid reflux. We investigated the role of resolvin D1 (RvD1) in protecting esophageal epithelial cells from damage caused by acid reflux. Through exposure tests, we found that RvD1 could effectively block oxidative stress and DNA damage linked to acid exposure.
Notably, RvD1 not only reduced harmful reactive oxygen species but also enhanced the cell's ability to repair DNA damage, signaling a promising potential for treatment in patients with gastroesophageal reflux disease. However, we need more studies to confirm its benefits in clinical settings. Easy to swallow Most Useful Review No reflux. This product does not repeat after taking it, and the capsules are simple to swallow. |
 Deva, Vegan Omega-3 DHA, 200 mg, 90 Softgels | | |
Resolvin D1's role in GERD treatmentResolvin D1 attenuates acid-induced DNA damage in esophageal epithelial cells and rat models of acid reflux. We investigated the role of resolvin D1 (RvD1) in protecting esophageal epithelial cells from damage caused by acid reflux. Through exposure tests, we found that RvD1 could effectively block oxidative stress and DNA damage linked to acid exposure.
Notably, RvD1 not only reduced harmful reactive oxygen species but also enhanced the cell's ability to repair DNA damage, signaling a promising potential for treatment in patients with gastroesophageal reflux disease. However, we need more studies to confirm its benefits in clinical settings. Relief from reflux Most Useful Review Excellent! This plant-based omega 3 doesn't taste of fish, and I feel better using it as fish omega caused me reflux. |
 NOW Foods, Omega-3 Fish Oil, 1000 mg, 180 EPA - 120 DHA, Odor Controlled, Enteric Coated, 90 Softgels | | |
Resolvin D1's role in GERD treatmentResolvin D1 attenuates acid-induced DNA damage in esophageal epithelial cells and rat models of acid reflux. We investigated the role of resolvin D1 (RvD1) in protecting esophageal epithelial cells from damage caused by acid reflux. Through exposure tests, we found that RvD1 could effectively block oxidative stress and DNA damage linked to acid exposure.
Notably, RvD1 not only reduced harmful reactive oxygen species but also enhanced the cell's ability to repair DNA damage, signaling a promising potential for treatment in patients with gastroesophageal reflux disease. However, we need more studies to confirm its benefits in clinical settings. Easier to tolerate Most Useful Review This fish oil concentrate is produced under strict quality control. I find it easier to tolerate than other fish oils, as it is enteric-coated to prevent reflux and has no strong odour. |
 BioGaia, Protectis Baby, Probiotic Drops with Vitamin D3, 0.34 fl oz (10 ml) | | |
Probiotic aids infant reflux issuesLactobacillus reuteri accelerates gastric emptying and improves regurgitation in infants. We explored how Lactobacillus reuteri affects regurgitation and gastric emptying in infants suffering from gastroesophageal reflux. By following 42 infants for 30 days, with some receiving the probiotic and others a placebo, we witnessed notable results.
Infants taking Lactobacillus reuteri showed significantly reduced episodes of regurgitation and faster gastric emptying. This probiotic appears to ease discomfort related to reflux, offering parents a potential solution to this common issue. Significant improvement Most Useful Review 17 people found this helpful Fussy baby? Buy these drops and thank me later! My NICU baby suffered from reflux, but after using these drops, his condition improved drastically. They worked just as well as the pricier version I initially used. I can’t recommend them highly enough. |
 NOW Foods, Magnesium Citrate, 400 mg, 120 Veg Capsules (133 mg per Capsule) | | |
Magnesium alginate effectively treats LPRMagnesium alginate in patients with laryngopharyngeal reflux. We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors. Reduced reflux discomfort Most Useful Review 45 people found this helpful Good evening, we are from Ukraine! I wish you all the best in this challenging time. This magnesium was prescribed by my doctor, so I take three capsules before bedtime as directed. The capsules are large, necessitating plenty of water. My gastrointestinal tract has improved, and the reflux gastritis has ceased to trouble me. My nervousness during PMS has also disappeared. |
 Nature's Bounty, Magnesium, 500 mg, 100 Coated Tablets | | |
Magnesium alginate effectively treats LPRMagnesium alginate in patients with laryngopharyngeal reflux. We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors. Reduced reflux symptoms Most Useful Review Great! I love it. It significantly improves my acid reflux! It also works wonders for heartburn and constipation too! |
 Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) | | |
Magnesium alginate effectively treats LPRMagnesium alginate in patients with laryngopharyngeal reflux. We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors. Reduces burning sensation Most Useful Review 2 people found this helpful Doctor prescribed antacids for acid reflux, but I opted for a natural remedy. Whenever I feel a burn in my stomach, I take a few of these tablets and find I no longer need antacids. It also aids digestion. |
 American Health, Ester-C with Citrus Bioflavonoids, 1,000 mg, 90 Capsules | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. No reflux experienced Most Useful Review 2 people found this helpful I find Ester-C to be the best vitamin C as it uses calcium ascorbate, which prevents heartburn or reflux. With my sensitive stomach, I handle this product very well, and it contains no added sugar or harmful sweeteners. It’s worth noting that sugar can hinder vitamin C absorption, so this formulation is ideal. |
 American Health, Ester-C with Citrus Bioflavonoids, 1,000 mg, 120 Vegetarian Tablets | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. No reflux issues Most Useful Review 4 people found this helpful Great product! The Ester-C formulation does not cause the acid reflux problems that regular Vitamin C does. |
 Jarrow Formulas, L-Glutamine, 1,000 mg, 100 Tablets | | |
Effectiveness of L-glutamine unclearNaturopathic Approach to Functional Dyspepsia: A Case Report. We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.
The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.
However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux. Eliminates reflux Most Useful Review 17 people found this helpful Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it. |
 NOW Foods, C-1000 with Bioflavonoids, 250 Veg Capsules | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. Relief from heartburn Most Useful Review My wife and I have tried a few other vitamin C brands that gave her terrible heartburn. We've been taking NOW vitamin C for some time now (on our second bottle), and she hasn't experienced any heartburn or acid reflux issues from it. The pills aren't tiny, but I find them easy to swallow. I can't recall when I last felt unwell, and I truly believe that taking vitamin C is the primary reason. I currently take two tablets daily (2,000 mg in total), one with breakfast and one with dinner. I usually increase to four when I've been around sick people. |
 Solaray, Timed Release Vitamin C with Rose Hips & Acerola, 1,000 mg, 250 Tablets | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. No reflux issue Most Useful Review 3 people found this helpful Good! Despite its size, the capsule has a coating that makes it easy to swallow. The two-stage time release allows for longer bioavailability compared to regular vitamin C. It has no flavor whatsoever and does not cause me acid reflux or any aftertaste, even when taken at bedtime. It is very beneficial for iron absorption. |
 Solgar, Ester-C® Plus, Vitamin C, 1,000 mg, 180 Tablets | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. Less acid reflux Most Useful Review It is easy to chew. Eat and take the vitamin C! Thanks to that, there is less acid reflux. |
 Solaray, Buffered Super Bio Vitamin C, 1,000 mg, 250 VegCaps (500 mg per Capsule) | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. Reflux relief Most Useful Review This vitamin C doesn't cause me reflux, which has been a welcome change after trying several other options that did. |
 Garden of Life, Vitamin Code, RAW Vitamin C, 60 Vegan Capsules | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. No reflux issues Most Useful Review I found this vitamin C to be the only one my husband can tolerate. He suffers from severe gastritis, and with other brands, he suddenly experiences reflux. This vitamin C does not cause that reaction. |
 NOW Foods, C-1000, 250 Tablets | | |
Vitamin C aids omeprazole therapyAntioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions. Amazing stomach tolerance Most Useful Review This product has been easy on my stomach! I suffer from acid reflux, and regular Vitamin C often upset my stomach. To my surprise, I had no trouble with these 1000mg tablets, even on an empty stomach. One a day is sufficient, but I might increase the dosage to two if I feel a cold coming on. |
 Garden of Life, Primal Defense, Ultra, Ultimate Probiotic Formula, 90 UltraZorbe Vegetarian Capsules | | |
Probiotics repair DNA in GERD sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer. Significant improvement Most Useful Review 2 people found this helpful Excellent product; it is a bit pricey, but certainly worth it 100%. I felt much better after my reflux gastritis and dysbacteriosis. |
 NOW Foods, Acidophilus Two Billion, 2 Billion CFU, 250 Veg Capsules | | |
Probiotic supplement reduces GERD symptomsEfficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. We aimed to find out how a food supplement containing probiotics, peptides, and vitamins impacts individuals with mild-to-moderate gastroesophageal reflux disease (GERD). In a thorough study, 56 participants were divided into two groups; one received the active supplement while the other got a placebo for 28 days.
The results were promising, showing a notable decrease in heartburn frequency and severity for those on the supplement. Additionally, they reported taking fewer over-the-counter medications, and their quality of life improved compared to the placebo group. This suggests that dietary supplements might offer a beneficial alternative for managing GERD symptoms. Eliminated heartburn Most Useful Review 3 people found this helpful The acidophilus bacillus thrives in the stomach, being the only beneficial bacterium able to survive in such acidic conditions, preventing Helicobacter pylori from settling. Thanks to acidophilus, my stomach remains healthy and prevents heartburn, as a very acidic environment ensures that the sphincter closes tightly, stopping stomach contents from refluxing into the oesophagus. This is how I overcame reflux esophagitis that had troubled me for years. |
 21st Century, Acidophilus Probiotic Blend, 150 Capsules | | |
Probiotic supplement reduces GERD symptomsEfficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. We aimed to find out how a food supplement containing probiotics, peptides, and vitamins impacts individuals with mild-to-moderate gastroesophageal reflux disease (GERD). In a thorough study, 56 participants were divided into two groups; one received the active supplement while the other got a placebo for 28 days.
The results were promising, showing a notable decrease in heartburn frequency and severity for those on the supplement. Additionally, they reported taking fewer over-the-counter medications, and their quality of life improved compared to the placebo group. This suggests that dietary supplements might offer a beneficial alternative for managing GERD symptoms. Prevents stomachaches Most Useful Review 12 people found this helpful I used to have severe stomachaches two to three times weekly. After starting these, I cancelled my doctor’s appointment as I hadn’t experienced pain in weeks. I had become resistant to all GERD medications. Since using this product, I’ve managed to stop taking those meds for years, but my acid reflux returns quickly if I run out. They are more affordable than my previous prescriptions, so I will continue using them. |
 Rainbow Light, Prenatal One™ Daily Multivitamin, High Potency, 150 Vegan Tablets | | |
No reflux symptoms Most Useful Review 1 people found this helpful No stomach irritation with this one. I've tried several multivitamins, and Rainbow Light is particularly gentle on my sensitive stomach. It doesn't cause reflux or nausea, making it ideal for me. I appreciate that I only need to take one tablet a day, rather than four. The tablets are not the smallest, but that doesn’t concern me. As for the smell, it's only slightly herby, which doesn’t bother me. No reflux issues Most Useful Review This antenatal multi is excellent. It’s easy to take and doesn’t cause reflux or make me feel sick like other ones do. I highly recommend it. |
 Garden of Life, Vitamin Code, RAW Prenatal, 90 Vegetarian Capsules | | |
Comfortable digestion Most Useful Review 1 people found this helpful This has been the best for tackling my reflux. I previously found it hard to swallow vitamins and experienced significant gastrointestinal discomfort. Since starting these, I feel much better without the usual disgust. It has transformed my vitamin routine. Natural composition Most Useful Review Luxury vitamins! In the later stages of pregnancy, my reflux has been concerning, but I appreciate the natural composition, which means no unpleasant vitamin burps. |
 NOW Foods, Apple Cider Vinegar, Extra Strength, 750 mg, 180 Tablets | | |
GutsyGum™ eases reflux symptomsEffect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal. We investigated whether GutsyGum™, a chewing gum with apple cider vinegar, could ease gastro-esophageal reflux (GER) symptoms after a reflux-heavy meal. In a double-blind study with 24 participants, we found that those who chewed GutsyGum™ reported significantly lower heartburn and acid reflux scores compared to those who used a placebo gum.
While there were positive trends in reducing symptoms like nausea and belching, these didn't reach statistical significance. Overall, GutsyGum™ shows promise for alleviating primary reflux symptoms, but it seems we still need to explore its full potential. Alleviates reflux symptoms Most Useful Review 16 people found this helpful Great acting nutraceutical! An excellent supplement to enhance protein absorption by improving stomach acidity. It's especially beneficial for those with low stomach acid, common in many. It helps regulate blood glucose, lowers triglycerides and LDL, normalises microflora, and reduces oxidative stress. Also effective against reflux and heartburn. |
 NOW Foods, Vitamin D-3, High Potency, 5,000 IU, 120 Softgels | | |
Vitamin D3 reduces early reflux inflammationElevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25 Dihydroxy Vitamin D3. We investigated how Vitamin D3 affects inflammation caused by reflux esophagitis—a condition where stomach acid irritates the esophagus. In our study, we used 70 male rats, dividing them into groups to examine the impact of Vitamin D3 at different doses on inflammation levels.
Our findings revealed that the levels of pro-inflammatory cytokines like IL-1β, IL-6, and IL-8 were significantly elevated in cases of acute reflux esophagitis. However, when we treated these rats with Vitamin D3, we observed that the inflammation markers decreased notably in the acute cases, while there wasn’t any significant change in the chronic cases.
Despite some improvements in cytokine levels with Vitamin D3, we noted that the overall morphological damage to the esophagus remained unchanged. Interestingly, while Vitamin D3 did raise serum calcium levels, it didn’t seem to help repair esophageal damage in the longer-term chronic setting.
These results suggest that while Vitamin D3 has the potential to mitigate inflammation in early stages of reflux esophagitis, it does not offer a complete solution regarding the physical damage caused by the condition over time. Effective dosage Most Useful Review This vitamin D is great for times when there’s a lack of sun. The dosage is good, there's no reflux, and the small cap size makes it easy to swallow. |
 Jarrow Formulas, Jarro-Dophilus EPS, 10 Billion CFU, 60 Veggie Capsules | | |
Lactobacillus improves infant reflux symptomsEffect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. We explored the impact of Lactobacillus reuteri NCIMB 30351 on common gastrointestinal issues in infants, focusing on gastroesophageal reflux. Conducted as a randomized and placebo-controlled trial, 90 infants received either the probiotic drops or a placebo for 25 days.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns. IBS improvement Most Useful Review 25 people found this helpful I'm surprised! I have tried probiotics before and they did nothing. This product is different; my IBS and reflux have noticeably improved in just four weeks. It's not perfect yet, but I'm hopeful for further improvement. |
 NOW Foods, Quercetin with Bromelain, 120 Veg Capsules | | |
Quercetin showed no significant benefitThe clinical effect of benesco™ on reflux symptoms: A double-blind randomized placebo-controlled trial. We conducted a double-blind, randomized placebo-controlled trial to evaluate how benesco™, a supplement containing quercetin, might help alleviate reflux symptoms. Our study involved 100 participants who were randomly assigned to receive either benesco™ or a placebo for six weeks.
The results showed that 39% of participants taking benesco™ experienced at least a 50% reduction in their reflux symptoms. However, this was not significantly different compared to the 47% success rate in the placebo group. Additionally, both groups reported a comparable number of reflux-free days and nights, offering no strong evidence that benesco™ is effective in treating reflux.
In conclusion, while we explored the potential of quercetin through benesco™, our findings indicate that it did not provide a significant benefit over the placebo. This suggests that those struggling with reflux might not find relief from this particular natural alternative. Effective for reflux Most Useful Review I purchased this for my mother in hopes of managing her IBS. The ingredients are very well formulated, and she found the capsule size acceptable. She loved it because it helped alleviate bloating, acid reflux, and heartburn. Quercetin is known as an antioxidant with anti-cancer properties and aids in fighting inflammation. I highly recommend it. |
 NOW Foods, Double Strength DHA-500 Fish Oil, 180 Softgels | | |
No reflux issues Most Useful Review 2 people found this helpful DHA is an essential part of my diet and the best omega I have tried. It leaves no odour, doesn't cause reflux, and is safe from mercury. As a nutritionist, I highly recommend this product. Good for reflux Most Useful Review 2 people found this helpful Fish oil is beneficial for brain and heart health. My eye doctor suggested this supplement for eye health. It’s a quality product that didn't cause reflux, nausea, or bad taste. Delivery was very prompt. |
 Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels | | |
No reflux issues Most Useful Review Exceptional. This is the best Omega 3 product I’ve tried. I’ve used about ten products, but this one stands out. The packaging is great, and it doesn’t trigger my reflux when taken between meals. Importantly, the EPA/DHA ratio is optimal according to research. Love it. No reflux experienced Most Useful Review Good purchase. I noticed the benefits quickly; the capsule is easy to swallow and doesn’t leave a fishy taste or cause reflux. Excellent product. |
 NOW Foods, Glutathione, 500 mg, 60 Veg Capsules | | |
Reflux relief Most Useful Review 13 people found this helpful This is the best glutathione I’ve ever taken. It's essential for a healthy liver, and I’ve noticed improvements in my skin, with my melasma nearly fading. I recommend it to anyone with reflux—my friend, who had seen multiple doctors without relief, tried this product and it worked wonders; she no longer suffers from reflux. I'm very grateful for the results. Digestive improvement Most Useful Review 1 people found this helpful Improved digestion 🌟👍 I would give this product more than five stars if I could. The quality of NOW products is excellent. I take a pill upon waking or an hour or two before meals, ideally with vitamin C for better absorption. After a month of use, I noticed significant improvement in my digestive system; I previously suffered from indigestion, but thankfully, it has improved greatly, relieving my nausea and reflux. The supply lasts about two months and it has no taste. May you be blessed. |
 Nordic Naturals, Arctic Cod Liver Oil, Lemon, 750 mg, 90 Soft Gels (250 mg per Soft Gel) | | |
No reflux noted Most Useful Review Best Cod Liver Oil with no fishy aftertaste or reflux. I only take 1 or 2 a day to maintain low cholesterol. I've been using fish oil for a long time, but for the last few years, I’ve exclusively chosen the Nordic brand for its quality. No reflux effect Most Useful Review This cod-liver oil capsules never give me reflux like other brands. I don’t detect any fishy taste and find them easy to swallow. |
 NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels | | |
Effective for reflux Most Useful Review 2 people found this helpful A fantastic product! I believe Lecithin is essential for everyone. My husband and I use it; he relies on it for liver support. He often experienced unpleasant sensations in his stomach, including heartburn and reflux. After starting the omega-3 complex, these symptoms disappeared almost immediately, and he continues to take it regularly. I highly recommend this sunflower Lecithin, which is GMO-free! Convenient capsules Most Useful Review This is the best product I've found on Iherb. The capsules are very convenient. My husband achieved excellent results in treating his reflux, and he also helped his father with chronic trigeminal facial nerve pain using it, alongside B vitamins. |
 NOW Foods, Milk Thistle Extract with Turmeric, 150 mg, 120 Veg Capsules | | |
Cleansing effects Most Useful Review 2 people found this helpful Under trial is an important food supplement for cleansing the liver and eliminating toxins. This reflects positively on skin health, enhances absorption of vitamins and minerals, aids in alleviating reflux esophagitis, balances stomach acidity, and reduces liver fat. Liver cleaning Most Useful Review I'm very pleased I tried this! I have been experiencing acid reflux and needed something to support my liver since I've been on numerous medications. Silymarin helped cleanse my liver effectively, and I'm glad I made this choice. |
 Doctor's Best, Glucosamine Chondroitin MSM with OptiMSM®, 240 Capsules | | |
No acid reflux Most Useful Review So glad I found this brand. Excellent quality, very agreeable with my particular system and no acid reflux. Easy to ingest, and I am starting to feel better. Quality makes a difference; these are affordable. Also on auto-ship, which is really convenient, and I will continue with it. Gastroesophageal relief Most Useful Review I bought this a long time ago, and it seems to have some unexpected benefits after taking it, as it relieves gastroesophageal reflux. |
 Doctor's Best, Hyaluronic Acid + Chondroitin Sulfate with BioCell Collagen, 180 Veggie Capsules | | |
Eased reflux symptoms Most Useful Review 1 people found this helpful I regularly consume this product, and although I was diagnosed with reflux esophagitis, I feel my condition has improved. It seems to positively affect the mucous membranes, too. Additionally, I had hip joint pain that caused a limp, but I am now walking comfortably. I've been using it consistently for about a year and can see its effects, despite the cost. I highly recommend it. Improved digestion Most Useful Review I have been dealing with acid reflux, and after reading various reviews, I was concerned due to the severity reported by many users. Fortunately, I have found relief without any resistance. My digestion has also improved significantly. |
 American Health, Papaya Enzyme with Chlorophyll, 250 Chewable Tablets | | |
Effective reflux remedy Most Useful Review 28 people found this helpful Superb remedy! I have suffered from superficial gastritis and reflux for a long time. This is one of the few products that helps me feel normal without unpleasant symptoms. Unlike other antacids, it truly alleviates my discomfort in the esophagus. I always keep it on hand and will continue to order it! Alternative for reflux Most Useful Review 2 people found this helpful This is a great alternative for alleviating reflux and dry mouth instead of unhealthy options. It also contains chlorophyll, which acts as an internal cleanser. |
 American Health, Original Chewable Papaya Enzyme, 45 mg, 600 Tablets (15 mg per Tablet) | | |
Stomach pain relief Most Useful Review 8 people found this helpful Amazing! My husband has battled gastric problems for four years. Last week, he woke up coughing from acid reflux, which was the last straw. Thankfully, I found this product. After just one day of use, along with Life Flora probiotics, his stomach pain disappeared, and he hasn't had any indigestion since starting this. It’s a fantastic product that truly saved my husband's stomach! Effective for acid reflux Most Useful Review 2 people found this helpful This is the best enzyme I've ever used, effective for acid reflux as well. It has a pleasant taste and an excellent price! |
 NOW Foods, Milk Thistle Extract, Double Strength, 300 mg, 200 Veg Capsules | | |
Reduced reflux symptoms Most Useful Review 2 people found this helpful I really liked this dietary supplement with milk thistle. My bile reflux has stopped, resulting in no more discomfort in my stomach after eating. It has helped cleanse my liver and normalise bile flow. I plan to continue taking it. Improved liver health Most Useful Review This product greatly supported my liver! I had indigestion and reflux, but after taking these capsules, I noticed a significant improvement in my condition. My appetite and mood returned, and the pain vanished. I feel cheerful now—this product really works! |
 NOW Foods, Flax Oil, 1,000 mg, 100 Softgels | | |
No reflux issue Most Useful Review Excellent! This flax oil is the best for Omega 3. It's vegan and easy to swallow, even though the capsule is large. Unlike cod liver oil, which caused me acidity and reflux, this one is gentle and doesn't lead to nausea. I recommend it to anyone advised by a nutrition consultant. No reflux benefits Most Useful Review I love this product! Unlike other flax oils, I don't experience reflux with this one, indicating better absorption. The quality is good, and I will certainly purchase it again. |
 American Health, Chewable Super Papaya Enzyme Plus, 360 Tablets | | |
Eliminates heartburn Most Useful Review 7 people found this helpful Bye-bye heartburn! Heartburn generally arises from insufficient stomach acid. This product effectively alleviates heartburn caused by low acid production, which accounts for 90% of acid reflux cases. Significant reduction Most Useful Review 4 people found this helpful My acid reflux has decreased by 90%. I've struggled with severe acid reflux, but this product has been ideal for me. Older individuals often produce insufficient stomach acid for digestion, leading to food refluxing alongside minimal acid. I highly recommend it. |
 NOW Foods, Super Omega 3-6-9, 1,200 mg, 90 Softgels | | |
No reflux experienced Most Useful Review A good fish oil with no reflux, unlike other brands I’ve tried. No reflux issue Most Useful Review Excellent Omega+ Fish Oil capsules! This is my second purchase of the 90 Softgel flip-top package, previously using a much larger bottle. The Omega Complex of 3-6-9, with 800 mg each of Borage Seed Oil, fish oil concentrate, and organic Flax Seed Oil, provides a perfect omega profile. Best of all, there's no reflux, making it ideal! |
 Source Naturals, Daily Essential Enzymes®, 500 mg, 240 Vegetarian Capsules | | |
Necessary for reflux Most Useful Review 2 people found this helpful These are essential for me. As I have acid reflux, they are a necessary purchase. I've been taking them for about five years — they truly work. I recommend these to anyone suffering from digestive issues. Ten stars, easy. Voice restoration Most Useful Review 1 people found this helpful These enzymes are remarkable! They restored my voice after I completely lost it due to acid reflux. I highly recommend them! |
 NOW Foods, B-50, 100 Veg Capsules | | |
No adverse reactions Most Useful Review The product contains the necessary B vitamins. I didn't experience any adverse reactions while taking this B complex alongside other supplements such as vitamin C with rose hips, D3, and ashwagandha. There was no acid reflux, and I feel less susceptible to muscle and nerve pains that people my age usually experience. No acidity reported Most Useful Review Vitamin B12 is only in micrograms. I experience a boost from the other B vitamins. I did not encounter any acidity or acid reflux with this supplement. The vitamin amounts are average, and I receive the energy I need throughout the day. I believe I will purchase it again in the future as it benefits my hormones and nerves. |
 NOW Foods, Super Enzymes, 180 Capsules | | |
Improved reflux symptoms Most Useful Review 18 people found this helpful At the age of 50, I developed reflux esophagitis due to poor digestive capacity. My symptoms have significantly improved since taking this product. The intense heartburn I experienced when eating certain foods, like curry, has eased considerably. Given the affordable price, I highly recommend it. Reduced heartburn incidents Most Useful Review 3 people found this helpful After learning enzymes could help with acid reflux, I decided to try this product. So far, it has worked wonders! When I take them with or before meals, I experience heartburn only 5% of the time. I've suffered from these issues my entire life and received prescriptions from GPs before, so this is a welcome change! |
 Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps | | |
No acid reflux Most Useful Review 2 people found this helpful This product meets everything I have read about how much bromelain to take and when to take it. Since starting this with Betain HCL and adjusting my diet, I have not experienced any acid reflux symptoms. I intend to keep taking this indefinitely. Keeps reflux at bay Most Useful Review Great! This is a very high-quality product that works effectively to keep acid reflux at bay. |
 NOW Foods, Odorless Garlic, Concentrated Extract, 50 mg, 250 Softgels (25 mg per Softgel) | | |
No aftertaste noted Most Useful Review This is by far the best garlic tablet I've tried. It has absolutely no aftertaste, reflux, or any symptoms at all after consumption! I will certainly purchase this product each time. No reflux experienced Most Useful Review Gentle on the stomach, it is indeed odourless. My mother is 81, and it does not cause her any reflux. I highly recommend it. |
 Kyolic, Aged Garlic Extract™, Cardiovascular Health, Original Formula 100, 600 mg, 300 Capsules (300 mg Per Capsule) | | |
No reflux issues Most Useful Review 1 people found this helpful Aged garlic extract is brilliant for heart health. It doesn’t leave any garlic aftertaste or cause reflux. Lower blood pressure Most Useful Review 1 people found this helpful Kyolic Aged Garlic Extract has been effective for me. My blood pressure readings are consistently lower since I began using it regularly, and my doctor has even taken me off medication. The capsules are easy to take, odourless, and have not caused any reflux. |
 NOW Foods, Certified Organic Inulin, Prebiotic Pure Powder, 8 oz (227 g) | | |
Reflux relief Most Useful Review It has resolved my issue of reflux and trapped gases, and I find it helpful overall. Medication-free reflux Most Useful Review This is my second order. I truly believe this prebiotic powder has helped me with my reflux. I am no longer taking reflux medication. |
 Pepto Bismol, Bismuth Subsalicylate, 262 mg, 40 Caplets | | |
Pain relief Most Useful Review 1 people found this helpful Magnificent! I always purchased this when travelling in the US and was thrilled to find it on IHerb. It works wonders for my exceptionally sensitive stomach, alleviating pain, reflux, and bloating. I always carry it with me; while I wouldn't recommend daily use, it’s invaluable for occasional stomach troubles! Reliable treatment Most Useful Review Excellent quality. Just what I needed. Pepto is a tried and trusted brand for good reason. I would highly recommend it; I use it for reflux and appreciate the compact packaging for on-the-go convenience. It’s consistently effective after meals or beforehand. Best value for money, too! |
 Jarrow Formulas, Methyl B-12, Extra Strength, Lemon, 1,000 mcg, 100 Chewable Tablets | | |
No worsening reflux Most Useful Review Nice! It tastes alright and seems strong enough while dissolving well without aggravating my reflux. I took this to help elevate my blood platelets, an issue from chemotherapy. I'm impressed with the quality, especially for the price. Improved reflux Most Useful Review Good value for money! Methylcobalamin is a bioavailable form of B12. I have stomach issues with reflux and low stomach acid, which leads to low B12. For me, a combination with Betaine HCL and Pepsin is essential. Stay healthy! |
 Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets | | |
Pain relief achieved Most Useful Review 60 people found this helpful Working preparation; relief for my mother’s reflux came quickly. After trying various medications with limited success, she began taking Elm. Within 3-4 days, the stomach pain subsided, and her mucous membranes started to heal. This product is effective for treating thinned gastric mucosa and may help normalise acidity when paired with enzymes. GERD pain reduction Most Useful Review 40 people found this helpful Slippery elm effectively manages GERD and reflux. My husband switched from PPI medication to taking two slippery elm capsules with meals. Although he still experienced pain occasionally, it has significantly reduced to twice a week. We also make a tea from the powder which alleviates pain immediately. |
 Tums, Ultra Strength Antacid, Assorted Berries, 1,000 mg, 160 Chewable Tablets | | |
Improved symptoms Most Useful Review 2 people found this helpful Fast shipping. I bought this because I have reflux symptoms. Taking one pill after each meal improved my symptoms within days. Helpful for reflux Most Useful Review 1 people found this helpful My mother experiences severe reflux, and this has helped her significantly. The size and taste are good, and the quality is excellent. |
 Nature's Way, NatureWorks®, Swedish Bitters, 3.38 fl oz (100 ml) | | |
Improves reflux symptoms Most Useful Review An excellent supplement for improving digestion. Bitters speed up bile movement, enhance intestinal motility, and promote regular bowel movements, which reduces my reflux. Following a nutritionist's advice, we are pleased with the results. Digestive relief Most Useful Review Really aids digestion. I have digestive issues, and sometimes food feels stuck. My reflux can be unbearable. Grapefruit helps, but this is perfect when I need more relief. I usually feel better within 5-10 minutes. The taste does not bother me. |
 NOW Foods, Slippery Elm, 400 mg, 100 Veg Capsules | | |
Pain relief achieved Most Useful Review 60 people found this helpful Working preparation; relief for my mother’s reflux came quickly. After trying various medications with limited success, she began taking Elm. Within 3-4 days, the stomach pain subsided, and her mucous membranes started to heal. This product is effective for treating thinned gastric mucosa and may help normalise acidity when paired with enzymes. GERD pain reduction Most Useful Review 40 people found this helpful Slippery elm effectively manages GERD and reflux. My husband switched from PPI medication to taking two slippery elm capsules with meals. Although he still experienced pain occasionally, it has significantly reduced to twice a week. We also make a tea from the powder which alleviates pain immediately. |
 NOW Foods, Zinc, 50 mg, 250 Tablets | | |
Effective with diet Most Useful Review Excellent for esophageal reflux, especially when combined with a proper diet. Symptoms disappeared Most Useful Review 1 people found this helpful After taking autophagy on an empty stomach in the morning, I experienced nausea, reflux, and headaches. Research showed it’s better not to take it on an empty stomach. Once I began taking it post-meals, those symptoms cleared up. Recently, I've switched to taking it at night rather than in the morning. |
 North American Herb & Spice, Oreganol, Oil of Wild Oregano, 1 fl oz (30 ml) | | |
Effective treatment Most Useful Review Following Dr. Karim Ali's advice, I took thyme oil with warm water, mastic capsules, licorice, and coconut butter for my heartburn, weak stomach acid, and reflux. Thankfully, I was cured. Now, I use thyme oil independently for indigestion and general health; it is an indispensable product. Instant relief Most Useful Review This product is a lifesaver for my reflux, providing immediate relief. I find it amazing, and its natural quality is exceptional. I wholeheartedly recommend it. |