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SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8
USERS' SCORE
Moderately Good
Based on 35 Reviews
7.9
Supplement Facts
Serving Size: 5 Drops
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
L.reuteriDSM 17938(L. reuteriProtectis®)
100 million CFU
†
Top Medical Research Studies
9.5
Lactobacillus reuteri reduces diarrhea
Lactobacillus reuteri protectis DSM 17938 at high doses versus placebo in children with acute gastroenteritis in a Pediatric Emergency Department.
High relevance for pediatric treatment
We conducted a randomized, controlled trial in a pediatric emergency department to evaluate how effective Lactobacillus reuteri DSM 17938 is for treating acute gastroenteritis in young children. Our findings revealed that the probiotic significantly reduced the duration and frequency of diarrhea compared to a placebo.
Specifically, children given L. reuteri experienced less watery diarrhea and shorter episodes than those receiving no treatment. This safe and easy-to-administer supplement could be a valuable addition to standard care, especially in reducing complications from gastroenteritis.
Specifically, children given L. reuteri experienced less watery diarrhea and shorter episodes than those receiving no treatment. This safe and easy-to-administer supplement could be a valuable addition to standard care, especially in reducing complications from gastroenteritis.
Read More
8
Lactobacillus reuteri aids diarrhea relief
Lactobacillus reuteri derived from horse alleviates Escherichia coli-induced diarrhea by modulating gut microbiota.
Relevant to probiotic treatments
We explored the effects of equine-derived Lactobacillus reuteri on diarrhea caused by E. coli. Our study highlighted that this probiotic could ease symptoms by improving gut microbiota balance and reinforcing the intestinal barrier.
We found that Lactobacillus reuteri supplementation not only curbed E. coli-induced diarrhea but also helped restore key tight junction proteins and adjusted levels of inflammatory markers. Additionally, it was effective in rebuilding beneficial gut bacteria that E. coli had diminished.
Overall, these findings point to the potential of Lactobacillus reuteri as a viable treatment option for diarrhea, with promising applications in probiotic product development.
We found that Lactobacillus reuteri supplementation not only curbed E. coli-induced diarrhea but also helped restore key tight junction proteins and adjusted levels of inflammatory markers. Additionally, it was effective in rebuilding beneficial gut bacteria that E. coli had diminished.
Overall, these findings point to the potential of Lactobacillus reuteri as a viable treatment option for diarrhea, with promising applications in probiotic product development.
Read More
8
Bile acid diarrhea management explored
Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea.
Significant findings on gut health
We explored the impact of Lactobacillus reuteri on diarrhea caused by bile acid metabolism disorders. By comparing healthy and affected piglets, we found that the treatment reduces the harmful compound CDCA-3β-glucuronide. This is achieved through the activation of certain pathways, including FXR-SIRT1-LKB1, which alleviates diarrhea and protects gut cells from apoptosis.
Overall, these results suggest that Lactobacillus reuteri could play a significant role in managing diarrhea related to bile acid disorders.
Overall, these results suggest that Lactobacillus reuteri could play a significant role in managing diarrhea related to bile acid disorders.
Read More
Most Useful Reviews
9.5
Magic for tummy troubles
I find this product incredibly useful for my children who suffer from stomach ache, diarrhoea, or constipation—it truly works like magic.
Read More
0
Disastrous experience
Gave it to my twins: NIGHTMARE. I regret trying this product on my newborn twins. After just two drops, chaos ensued—both babies screamed in painful reactions followed by episodes of very severe dark green diarrhoea. I immediately discontinued use due to the overwhelming distress and horrific smell. Thankfully, they improved shortly after stopping the probiotics.
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9.5
Life-changing experience
Worth every penny! I rarely write reviews, but this changed my life! As a mother of five, finding the right formula has been challenging. My baby experienced severe gas and fussiness, especially during bouts of diarrhea. After using these specific probiotics, they have helped with fussy behaviour tremendously. Although it takes weeks to see results, it’s so worth it!
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Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8
9.5
Lactobacillus reuteri reduces diarrhea
Lactobacillus reuteri protectis DSM 17938 at high doses versus placebo in children with acute gastroenteritis in a Pediatric Emergency Department.
High relevance for pediatric treatment
We conducted a randomized, controlled trial in a pediatric emergency department to evaluate how effective Lactobacillus reuteri DSM 17938 is for treating acute gastroenteritis in young children. Our findings revealed that the probiotic significantly reduced the duration and frequency of diarrhea compared to a placebo.
Specifically, children given L. reuteri experienced less watery diarrhea and shorter episodes than those receiving no treatment. This safe and easy-to-administer supplement could be a valuable addition to standard care, especially in reducing complications from gastroenteritis.
Specifically, children given L. reuteri experienced less watery diarrhea and shorter episodes than those receiving no treatment. This safe and easy-to-administer supplement could be a valuable addition to standard care, especially in reducing complications from gastroenteritis.
Read More
9
Effect of QP and L. reuteri on gut health
Dietary Qiwenghuangbo powder-enriched Limosilactobacillus reuteri protects the intestinal epithelium and alleviates inflammation via a strain-specific mechanism.
Relevant for gut health research
In our exploration of the effects of Qiwenghuangbo powder (QP) on weaned piglets, we found that a diet enriched with QP improved intestinal health and reduced diarrhea.
We noted that this improvement was linked to the enhanced growth and colonization of Limosilactobacillus reuteri, a beneficial bacteria.
Specifically, two strains of L. reuteri showed promise in alleviating inflammation and controlling harmful gut pathogens, confirming QP's potential for promoting gut health in young animals.
We noted that this improvement was linked to the enhanced growth and colonization of Limosilactobacillus reuteri, a beneficial bacteria.
Specifically, two strains of L. reuteri showed promise in alleviating inflammation and controlling harmful gut pathogens, confirming QP's potential for promoting gut health in young animals.
Read More
9
Probiotics reduce VAP and diarrhea
Probiotic prophylaxis to prevent ventilator-associated pneumonia in children on mechanical ventilation: A randomized double-blind clinical trial.
High relevance to prevention strategies.
We conducted a randomized, double-blind clinical trial to explore the role of probiotics in preventing ventilator-associated pneumonia (VAP) and diarrhea in children on mechanical ventilation. Our study included 72 children, divided into those receiving Limosilactobacillus reuteri probiotics and a placebo.
We found that probiotics significantly reduced the risk of VAP and diarrhea compared to the placebo. This indicates that probiotics could be an effective strategy for improving health outcomes in vulnerable pediatric patients.
We found that probiotics significantly reduced the risk of VAP and diarrhea compared to the placebo. This indicates that probiotics could be an effective strategy for improving health outcomes in vulnerable pediatric patients.
Read More
8
Vitamin D alleviates rotavirus diarrhea
1α,25-hydroxyvitamin D alleviated rotavirus infection induced ferroptosis in IPEC-J2 cells by regulating the ATF3-SLC7A11-GPX4 axis.
Study demonstrates vitamin D's relevance
We observed that rotavirus infection predominantly affects mature intestinal cells, leading to severe digestive issues, including diarrhea. This research delved into how 1α,25-hydroxyvitamin D (commonly known as vitamin D) might be influential in mitigating these detrimental effects. Various experiments were conducted with IPEC-J2 cells to analyze the impact of rotavirus on cell death and inflammation.
Our findings revealed that rotavirus not only led to cell death but also induced a specific form of cell death called ferroptosis. This situation was characterized by increased reactive oxygen species and decreased mitochondrial activity, factors that can worsen inflammation and damage gut cells. Interestingly, treatment with vitamin D significantly reduced these harmful effects. It appeared to operate through a specific pathway involving key proteins that protect cells from oxidative stress.
In summary, our study suggests that vitamin D has a protective role and inhibits rotavirus-induced cell damage and ferroptosis. By regulating certain cellular pathways, vitamin D may alleviate the intestinal distress caused by rotavirus, offering a potential therapeutic avenue against diarrhea linked to this virus. Overall, this research supports the consideration of vitamin D as a beneficial treatment in managing rotavirus infections and their associated symptoms.
Our findings revealed that rotavirus not only led to cell death but also induced a specific form of cell death called ferroptosis. This situation was characterized by increased reactive oxygen species and decreased mitochondrial activity, factors that can worsen inflammation and damage gut cells. Interestingly, treatment with vitamin D significantly reduced these harmful effects. It appeared to operate through a specific pathway involving key proteins that protect cells from oxidative stress.
In summary, our study suggests that vitamin D has a protective role and inhibits rotavirus-induced cell damage and ferroptosis. By regulating certain cellular pathways, vitamin D may alleviate the intestinal distress caused by rotavirus, offering a potential therapeutic avenue against diarrhea linked to this virus. Overall, this research supports the consideration of vitamin D as a beneficial treatment in managing rotavirus infections and their associated symptoms.
Read More
8
Bile acid diarrhea management explored
Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea.
Significant findings on gut health
We explored the impact of Lactobacillus reuteri on diarrhea caused by bile acid metabolism disorders. By comparing healthy and affected piglets, we found that the treatment reduces the harmful compound CDCA-3β-glucuronide. This is achieved through the activation of certain pathways, including FXR-SIRT1-LKB1, which alleviates diarrhea and protects gut cells from apoptosis.
Overall, these results suggest that Lactobacillus reuteri could play a significant role in managing diarrhea related to bile acid disorders.
Overall, these results suggest that Lactobacillus reuteri could play a significant role in managing diarrhea related to bile acid disorders.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 35 Reviews
7.9
10
Healthy gut emphasis
Probiotics are essential for a healthy gut in children. My baby has not experienced diarrhoea since birth, even when we introduced solids and new foods. I believe every baby should have this.
10
Colic and gas relief
Excellent for colic, diarrhoea, and gas relief. I keep reordering due to its effectiveness and reasonable price.
9.5
Magic for tummy troubles
I find this product incredibly useful for my children who suffer from stomach ache, diarrhoea, or constipation—it truly works like magic.
9.5
Lactose allergy solution
The quality is excellent. I used it for my infant son, who has a lactose allergy and had diarrhoea and constant gas. This product has helped him significantly.
9.5
Improved digestion
This great tool has corrected my child's digestion. Even with severe diarrhoea from teething, it has proved effective; I add it to his food without any taste or smell.
