Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
USERS' SCORE
Good
Based on 24 Reviews
8.8
Supplement Facts
Serving Size: 5 Drops
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
L.reuteriDSM 17938(L. reuteriProtectis®)
100 million CFU
†
Top Medical Research Studies
8
We explored the potential benefits of vitamin D supplementation for reducing the risk of influenza infections. Through a comprehensive analysis of multiple Randomized Controlled Trials (RCTs), we aimed to clarify whether taking vitamin D can help prevent the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
Read More
8
We conducted a practical study to investigate how daily vitamin D3 supplementation at 5000 IU might help reduce flu-like illnesses in healthcare workers. This was especially important during the COVID-19 pandemic, where preventing viral infections is crucial for those on the front lines.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
Read More
8
We investigated the intriguing link between sunlight exposure, vitamin D production, and flu incidence. The study revealed that higher levels of sunlight are associated with a noticeable decrease in flu cases, particularly during the severe H1N1 epidemic in the fall of 2009.
Our findings indicate that a 10% increase in relative sunlight can lower the flu index during September and October by about 1.1 points on a 10-point scale. This layer of sunlight acts like a shield, helping protect individuals from catching the flu, thanks in part to its role in vitamin D production in our bodies.
A complementary study in New York State backed up these observations, reinforcing the message that adequate sunlight might be key in reducing flu incidence.
Our findings indicate that a 10% increase in relative sunlight can lower the flu index during September and October by about 1.1 points on a 10-point scale. This layer of sunlight acts like a shield, helping protect individuals from catching the flu, thanks in part to its role in vitamin D production in our bodies.
A complementary study in New York State backed up these observations, reinforcing the message that adequate sunlight might be key in reducing flu incidence.
Read More
Most Useful Reviews
10
Gut restoration
129 people found this helpful
Fussy baby? Buy these now! My NICU baby had stomach issues after IV antibiotics. I initially tried a more expensive probiotic but found this one worked just as well and was cheaper. These drops have drastically improved his gut health, significantly reducing fussiness and reflux. I cannot recommend them highly enough!
Read More
7.5
Reduced discomfort
60 people found this helpful
These are a gift from god! I was sceptical about giving probiotics to my 4-month-old, but it was the best decision. He suffered from terrible gas and reflux, with painful nights. The doctors prescribed Zantac, but it didn’t address spitting up. This probiotic has greatly alleviated his reflux. Although he still spits up occasionally, it’s much less than before. He now poops every other day and the consistency has improved significantly.
Read More
9
Crying reduced
11 people found this helpful
Great for colic and food allergies. My daughter had colic, food allergies, and issues passing gas. After weeks of persistent crying, we switched to a suitable formula and started this product. Within three days, there was a noticeable reduction in her fussiness. By the week's end, she was passing gas easily and crying much less. I had tried multiple probiotics and remedies, but this one worked wonders!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
- All Researches
9
We recently examined how vitamin D impacts our body's response to influenza H1N1, an important viral infection. Utilizing 142 clinical cases from the Department of Otolaryngology at Sun Yat-sen University, we dug into the effects of vitamin D deficiency on chronic rhinosinusitis (CRS), a condition that frequently involves damage to the airway's lining. By studying airway organoids treated with vitamin D, we were able to simulate how this treatment might bolster our defenses against flu viruses and bacteria like Staphylococcus aureus.
Our observations showed that many patients with CRS suffered from vitamin D deficiency. Notably, those who received vitamin D treatment exhibited faster cell growth in the nasal epithelium. When exposed to the H1N1 virus, these treated organoids demonstrated a remarkable ability to fend off the infection better than those without vitamin D. This protection stemmed from enhancements in host defenses, including improved production of antimicrobial proteins, reduced inflammation, and better epithelial integrity—crucial factors in fighting off infections.
We also uncovered some fascinating insights about the biological mechanisms at work. Vitamin D seemed to actively influence how epithelial cells develop and repair themselves while managing immune responses against infections. These findings underscore the significance of addressing vitamin D deficiency, especially for those vulnerable to respiratory illnesses.
Our observations showed that many patients with CRS suffered from vitamin D deficiency. Notably, those who received vitamin D treatment exhibited faster cell growth in the nasal epithelium. When exposed to the H1N1 virus, these treated organoids demonstrated a remarkable ability to fend off the infection better than those without vitamin D. This protection stemmed from enhancements in host defenses, including improved production of antimicrobial proteins, reduced inflammation, and better epithelial integrity—crucial factors in fighting off infections.
We also uncovered some fascinating insights about the biological mechanisms at work. Vitamin D seemed to actively influence how epithelial cells develop and repair themselves while managing immune responses against infections. These findings underscore the significance of addressing vitamin D deficiency, especially for those vulnerable to respiratory illnesses.
Read More
8
We explored how vitamin D supplementation might help reduce the risk of respiratory infections, particularly the flu, in care homes. Our systematic review of several randomized controlled trials focused on interventions to reduce the transmission of acute respiratory infections, looking beyond just vaccines.
Our findings highlighted that high-dose vitamin D supplementation led to a significant decrease in the incidence of acute respiratory infections, reducing the likelihood of getting sick. Specifically, one trial indicated a 40% reduction in these infections among participants receiving vitamin D compared to those who did not.
However, not all studies we reviewed showed compelling results for related supplements like vitamins, minerals, probiotics, and herbal aids, which did not significantly impact infection rates. This means that while vitamin D supplementation shows promise, more research is needed to fully understand its effects and confirm its benefits in combating flu and other respiratory illnesses.
Our findings highlighted that high-dose vitamin D supplementation led to a significant decrease in the incidence of acute respiratory infections, reducing the likelihood of getting sick. Specifically, one trial indicated a 40% reduction in these infections among participants receiving vitamin D compared to those who did not.
However, not all studies we reviewed showed compelling results for related supplements like vitamins, minerals, probiotics, and herbal aids, which did not significantly impact infection rates. This means that while vitamin D supplementation shows promise, more research is needed to fully understand its effects and confirm its benefits in combating flu and other respiratory illnesses.
Read More
8
We conducted a practical study to investigate how daily vitamin D3 supplementation at 5000 IU might help reduce flu-like illnesses in healthcare workers. This was especially important during the COVID-19 pandemic, where preventing viral infections is crucial for those on the front lines.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
Read More
8
We explored the potential benefits of vitamin D supplementation for reducing the risk of influenza infections. Through a comprehensive analysis of multiple Randomized Controlled Trials (RCTs), we aimed to clarify whether taking vitamin D can help prevent the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
Read More
8
We investigated the intriguing link between sunlight exposure, vitamin D production, and flu incidence. The study revealed that higher levels of sunlight are associated with a noticeable decrease in flu cases, particularly during the severe H1N1 epidemic in the fall of 2009.
Our findings indicate that a 10% increase in relative sunlight can lower the flu index during September and October by about 1.1 points on a 10-point scale. This layer of sunlight acts like a shield, helping protect individuals from catching the flu, thanks in part to its role in vitamin D production in our bodies.
A complementary study in New York State backed up these observations, reinforcing the message that adequate sunlight might be key in reducing flu incidence.
Our findings indicate that a 10% increase in relative sunlight can lower the flu index during September and October by about 1.1 points on a 10-point scale. This layer of sunlight acts like a shield, helping protect individuals from catching the flu, thanks in part to its role in vitamin D production in our bodies.
A complementary study in New York State backed up these observations, reinforcing the message that adequate sunlight might be key in reducing flu incidence.
Read More
User Reviews
USERS' SCORE
Good
Based on 24 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
Gut restoration
129 people found this helpful
Fussy baby? Buy these now! My NICU baby had stomach issues after IV antibiotics. I initially tried a more expensive probiotic but found this one worked just as well and was cheaper. These drops have drastically improved his gut health, significantly reducing fussiness and reflux. I cannot recommend them highly enough!
Read More
7.5
Reduced discomfort
60 people found this helpful
These are a gift from god! I was sceptical about giving probiotics to my 4-month-old, but it was the best decision. He suffered from terrible gas and reflux, with painful nights. The doctors prescribed Zantac, but it didn’t address spitting up. This probiotic has greatly alleviated his reflux. Although he still spits up occasionally, it’s much less than before. He now poops every other day and the consistency has improved significantly.
Read More
9
Crying reduced
11 people found this helpful
Great for colic and food allergies. My daughter had colic, food allergies, and issues passing gas. After weeks of persistent crying, we switched to a suitable formula and started this product. Within three days, there was a noticeable reduction in her fussiness. By the week's end, she was passing gas easily and crying much less. I had tried multiple probiotics and remedies, but this one worked wonders!
Read More
9
Life-changing effects
7 people found this helpful
Worth every penny! I rarely write reviews, but this product is fantastic! I have five children and encountered numerous feeding issues, including reflux and gas. The doctor provided a sample of probiotics during a bout of diarrhoea, and it changed everything. My exclusively breastfed baby is now much happier, with less fussiness and gas. When we ran out, the results were disastrous, but after restarting, she improved within days. If your baby struggles with gas or fussiness, give this a try!
Read More
9
Reflux improvement
3 people found this helpful
The best we've used. Our pediatrician gave us samples of this probiotic, and it worked wonders for my 6-month-old who had reflux. After running out of samples, I tried a cheaper brand recommended by a friend, but within days, my baby began spitting up again. I ordered more from Amazon, and within two days of resuming the original, he hasn’t spat up at all and is also pooping better.
Read More
Frequently Asked Questions
7.5
Improves flu symptoms
1 people found this helpful
Quick fix for nausea, diarrhoea, tummy ache or even flu symptoms! This strain of bacteria is beneficial for children, particularly when they experience nausea, vomiting, diarrhoea, or flu-like symptoms. With just a few doses, I noticed a marked improvement! It's best used on an empty stomach a few minutes before food or drink. The taste is tolerable, even for babies. I can vouch for the quality as its action is remarkably fast. Within 2-3 days of taking this (as often as needed throughout the day), my child began to recover. I once used it on my elderly mother who had severe gastroenteritis, and after just one dose, she ceased vomiting. Continuing to take it every couple of hours helps balance gut bacteria.
7.5
Relieves reflux struggles
1 people found this helpful
There’s a good review about it that compelled me to try. My baby has colic and reflux, which always made feeding a challenge. Since starting this probiotic, he can drink his milk without struggle. I noticed a difference within four days. I wish I had tried it earlier!
6
Improves digestion quickly
I began using these for my infant as she had terrible reflux and an overall upset stomach. I was sceptical about the cost but thought it worthwhile to try. After using them for some time, her condition improved. However, I wasn’t sure if they were effective until I paused and didn’t reorder. Within two days, her stomach issues worsened. After waiting a few days to evaluate the situation, I reordered the probiotics. Within two days of restarting them, she was back to her usual cheerful self!
9
Effectively aids reflux
1 people found this helpful
מצוין! It helped me greatly with my twin babies. Reflux medication did not work, but this probiotic did.
9
Flu frequency decreased
I noticed a significant drop in the frequency of stomach flu! I alternate this with vitamins.
9
Great post-flu
This probiotic is great for babies! Recommended by our paediatrician for my 11-month-old (6 months then) post catching flu A. My baby loves taking it daily; it must taste alright. It’s much cheaper than going through a paediatrician, so I will keep buying from IHerb.
7.5
Supports immune system
My kids enjoy taking this every day. It seems to work well on their immune systems. I will see how it helps during the flu season.
8
We explored how vitamin D supplementation might help reduce the risk of respiratory infections, particularly the flu, in care homes. Our systematic review of several randomized controlled trials focused on interventions to reduce the transmission of acute respiratory infections, looking beyond just vaccines.
Our findings highlighted that high-dose vitamin D supplementation led to a significant decrease in the incidence of acute respiratory infections, reducing the likelihood of getting sick. Specifically, one trial indicated a 40% reduction in these infections among participants receiving vitamin D compared to those who did not.
However, not all studies we reviewed showed compelling results for related supplements like vitamins, minerals, probiotics, and herbal aids, which did not significantly impact infection rates. This means that while vitamin D supplementation shows promise, more research is needed to fully understand its effects and confirm its benefits in combating flu and other respiratory illnesses.
Our findings highlighted that high-dose vitamin D supplementation led to a significant decrease in the incidence of acute respiratory infections, reducing the likelihood of getting sick. Specifically, one trial indicated a 40% reduction in these infections among participants receiving vitamin D compared to those who did not.
However, not all studies we reviewed showed compelling results for related supplements like vitamins, minerals, probiotics, and herbal aids, which did not significantly impact infection rates. This means that while vitamin D supplementation shows promise, more research is needed to fully understand its effects and confirm its benefits in combating flu and other respiratory illnesses.
8
We conducted a practical study to investigate how daily vitamin D3 supplementation at 5000 IU might help reduce flu-like illnesses in healthcare workers. This was especially important during the COVID-19 pandemic, where preventing viral infections is crucial for those on the front lines.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
Our study involved 255 healthcare workers who received the vitamin D3 supplement for at least two months and compared them to a control group of 2827 workers who did not receive the supplement. We asked participants to monitor themselves for any flu-like symptoms and report for COVID-19 testing accordingly.
The results were promising; those supplementing with vitamin D experienced a significant reduction in the incidence of flu-like illnesses. The numbers showed a noteworthy drop in non-COVID-19 flu-like illness rates among those taking the supplement. However, when it came to COVID-19 related flu-like illnesses, the difference was not statistically significant.
Overall, our exploration of vitamin D3's effects suggests that it may be a beneficial addition to the health routines of healthcare workers to stave off flu-like illnesses, although its influence on COVID-19 specifically requires further investigation.
5
We conducted a randomized, double-blind, controlled trial to explore whether vitamin D supplementation could lower the risk of flu among young children. The study involved 248 participants aged two to five years from daycare centers in Taiwan, who were divided into two groups: one received 2000 IU of vitamin D daily, while the other group received a placebo for one month.
The results were intriguing. We found an 84% relative risk reduction for flu infection in the vitamin D group compared to the placebo group. However, this finding did not achieve statistical significance, which means we can't be certain of its importance. The data suggested that the placebo group might have a higher chance of getting the flu, but again, the results were not definitive.
Additionally, no significant differences were observed in terms of enterovirus infections between the two groups, and the same trend was seen among household members of the children. Everyone who received the vitamin D treatment managed to raise their vitamin D levels above 30 ng/ml, indicating that the supplementation was effective in boosting their vitamin D status.
Overall, while vitamin D supplementation might offer some protective effect against flu in preschoolers, the evidence does not strongly support this. We recommend further research to fully understand the impact.
The results were intriguing. We found an 84% relative risk reduction for flu infection in the vitamin D group compared to the placebo group. However, this finding did not achieve statistical significance, which means we can't be certain of its importance. The data suggested that the placebo group might have a higher chance of getting the flu, but again, the results were not definitive.
Additionally, no significant differences were observed in terms of enterovirus infections between the two groups, and the same trend was seen among household members of the children. Everyone who received the vitamin D treatment managed to raise their vitamin D levels above 30 ng/ml, indicating that the supplementation was effective in boosting their vitamin D status.
Overall, while vitamin D supplementation might offer some protective effect against flu in preschoolers, the evidence does not strongly support this. We recommend further research to fully understand the impact.
References
- Willcox ML, Lavu D, Yousaf U, Dalton S, Roberts N, et al. The effectiveness of interventions to reduce the transmission of acute respiratory infections in care homes: a systematic review. J Public Health (Oxf). 2024;46:551. doi:10.1093/pubmed/fdae178
- Liao S, Huang Y, Zhang J, Xiong Q, Chi M, et al. Vitamin D promotes epithelial tissue repair and host defense responses against influenza H1N1 virus and Staphylococcus aureus infections. Respir Res. 2023;24:175. doi:10.1186/s12931-023-02477-4
- van Helmond N, Brobyn TL, LaRiccia PJ, Cafaro T, Hunter K, et al. Vitamin D3 Supplementation at 5000 IU Daily for the Prevention of Influenza-like Illness in Healthcare Workers: A Pragmatic Randomized Clinical Trial. Nutrients. 2022;15. doi:10.3390/nu15010180
- Arora J, Patel DR, Nicol MJ, Field CJ, Restori KH, et al. Vitamin D and the Ability to Produce 1,25(OH)D Are Critical for Protection from Viral Infection of the Lungs. Nutrients. 2022;14. doi:10.3390/nu14153061
- Huang YN, Chi H, Chiu NC, Huang CY, Li ST, et al. A randomized trial of vitamin D supplementation to prevent seasonal influenza and enterovirus infection in children. J Microbiol Immunol Infect. 2022;55:803. doi:10.1016/j.jmii.2022.01.003
- Zhu Z, Zhu X, Gu L, Zhan Y, Chen L, et al. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials. Front Nutr. 2021;8:799709. doi:10.3389/fnut.2021.799709
- Godan Hauptman A, Lukić-Grlić A, Vraneš J, Milošević M, Gagro A. The effect of standard-dose wintertime vitamin D supplementation on influenza infection in immunized nursing home elderly residents. Croat Med J. 2021;62:495.
- Abioye AI, Bromage S, Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob Health. 2021;6. doi:10.1136/bmjgh-2020-003176
- Slusky DJG, Zeckhauser RJ. Sunlight and Protection Against Influenza. Econ Hum Biol. 2021;40:100942. doi:10.1016/j.ehb.2020.100942
